1o9w - Revision history

OCA at 12:32, 13 December 2023

OCA — Wed, 13 Dec 2023 12:32:35 GMT

←Older revision		Revision as of 12:32, 13 December 2023
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	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1o9w]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1O9W OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1O9W FirstGlance]. <br>		<table><tr><td colspan='2'>[[1o9w]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1O9W OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1O9W FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.65Å</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1o9w FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1o9w OCA], [https://pdbe.org/1o9w PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1o9w RCSB], [https://www.ebi.ac.uk/pdbsum/1o9w PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1o9w ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1o9w FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1o9w OCA], [https://pdbe.org/1o9w PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1o9w RCSB], [https://www.ebi.ac.uk/pdbsum/1o9w PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1o9w ProSAT]</span></td></tr>
	</table>		</table>

OCA at 12:25, 1 February 2023

OCA — Wed, 01 Feb 2023 12:25:00 GMT

←Older revision		Revision as of 12:25, 1 February 2023
Line 3:		Line 3:
	<StructureSection load='1o9w' size='340' side='right'caption='[[1o9w]], [[Resolution\|resolution]] 1.65Å' scene=''>		<StructureSection load='1o9w' size='340' side='right'caption='[[1o9w]], [[Resolution\|resolution]] 1.65Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1o9w]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/~~"bacillus_coli"_migula_1895 "bacillus~~ coli~~" migula 1895~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1O9W OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1O9W FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1o9w]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1O9W OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1O9W FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1o9v\|1o9v]], [[1o9z\|1o9z]]</div></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1o9w FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1o9w OCA], [https://pdbe.org/1o9w PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1o9w RCSB], [https://www.ebi.ac.uk/pdbsum/1o9w PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1o9w ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1o9w FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1o9w OCA], [https://pdbe.org/1o9w PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1o9w RCSB], [https://www.ebi.ac.uk/pdbsum/1o9w PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1o9w ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[https://www.uniprot.org/uniprot/F17AG_ECOLX F17AG_ECOLX]] Essential fimbrial adhesion factor that mediates binding to N-acetylglucosamine-containing receptors in the host intestinal microvilli, leading to colonization of the intestinal tissue, and diarrhea or septicemia. Also confers adhesiveness to laminin and basement membranes.	+	[https://www.uniprot.org/uniprot/F17AG_ECOLX F17AG_ECOLX] Essential fimbrial adhesion factor that mediates binding to N-acetylglucosamine-containing receptors in the host intestinal microvilli, leading to colonization of the intestinal tissue, and diarrhea or septicemia. Also confers adhesiveness to laminin and basement membranes.
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 26:		Line 25:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Bacillus~~ coli ~~migula 1895~~]]	+	[[Category: Escherichia coli]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Bouckaert, J]]	+	[[Category: Bouckaert J]]
-	[[Category: Brosens, E]]	+	[[Category: Brosens E]]
-	[[Category: Buts, L]]	+	[[Category: Buts L]]
-	[[Category: Genst, E De]]	+	[[Category: De Genst E]]
-	[[Category: Greve, H De]]	+	[[Category: De Greve H]]
-	[[Category: Lahmann, M]]	+	[[Category: Lahmann M]]
-	[[Category: Loris, R]]	+	[[Category: Loris R]]
-	[[Category: Messens, J]]	+	[[Category: Messens J]]
-	[[Category: Oscarson, S]]	+	[[Category: Oscarson S]]
-	[[Category: Wyns, L]]	+	[[Category: Wyns L]]
-	~~[[Category: Bacterial adhesin]]~~	+
-	~~[[Category: Bacterial attachment]]~~	+
-	~~[[Category: Immunoglobulin fold]]~~	+
-	~~[[Category: Sugar binding protein]]~~	+
-	~~[[Category: Sugar binding protein pathogenesis~~]]	+

OCA at 06:00, 28 April 2021

OCA — Wed, 28 Apr 2021 06:00:22 GMT

←Older revision		Revision as of 06:00, 28 April 2021
Line 3:		Line 3:
	<StructureSection load='1o9w' size='340' side='right'caption='[[1o9w]], [[Resolution\|resolution]] 1.65Å' scene=''>		<StructureSection load='1o9w' size='340' side='right'caption='[[1o9w]], [[Resolution\|resolution]] 1.65Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1o9w]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1O9W OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1O9W FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1o9w]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1O9W OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1O9W FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1o9v\|1o9v]], [[1o9z\|1o9z]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1o9v\|1o9v]], [[1o9z\|1o9z]]</div></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1o9w FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1o9w OCA], [~~http~~://pdbe.org/1o9w PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=1o9w RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/1o9w PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=1o9w ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1o9w FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1o9w OCA], [https://pdbe.org/1o9w PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1o9w RCSB], [https://www.ebi.ac.uk/pdbsum/1o9w PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1o9w ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[~~http~~://www.uniprot.org/uniprot/F17AG_ECOLX F17AG_ECOLX]] Essential fimbrial adhesion factor that mediates binding to N-acetylglucosamine-containing receptors in the host intestinal microvilli, leading to colonization of the intestinal tissue, and diarrhea or septicemia. Also confers adhesiveness to laminin and basement membranes.	+	[[https://www.uniprot.org/uniprot/F17AG_ECOLX F17AG_ECOLX]] Essential fimbrial adhesion factor that mediates binding to N-acetylglucosamine-containing receptors in the host intestinal microvilli, leading to colonization of the intestinal tissue, and diarrhea or septicemia. Also confers adhesiveness to laminin and basement membranes.
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==

OCA at 06:53, 24 July 2019

OCA — Wed, 24 Jul 2019 06:53:36 GMT

←Older revision		Revision as of 06:53, 24 July 2019
Line 1:		Line 1:

	==F17-aG lectin domain from Escherichia coli in complex with N-acetyl-glucosamine==		==F17-aG lectin domain from Escherichia coli in complex with N-acetyl-glucosamine==
-	<StructureSection load='1o9w' size='340' side='right' caption='[[1o9w]], [[Resolution\|resolution]] 1.65Å' scene=''>	+	<StructureSection load='1o9w' size='340' side='right'caption='[[1o9w]], [[Resolution\|resolution]] 1.65Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1o9w]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1O9W OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1O9W FirstGlance]. <br>		<table><tr><td colspan='2'>[[1o9w]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1O9W OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1O9W FirstGlance]. <br>
Line 19:		Line 19:
	</div>		</div>
	<div class="pdbe-citations 1o9w" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 1o9w" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[Adhesin 3D structures\|Adhesin 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
Line 24:		Line 27:
	</StructureSection>		</StructureSection>
	[[Category: Bacillus coli migula 1895]]		[[Category: Bacillus coli migula 1895]]
		+	[[Category: Large Structures]]
	[[Category: Bouckaert, J]]		[[Category: Bouckaert, J]]
	[[Category: Brosens, E]]		[[Category: Brosens, E]]

OCA at 09:45, 1 November 2017

OCA — Wed, 01 Nov 2017 09:45:25 GMT

←Older revision		Revision as of 09:45, 1 November 2017
Line 1:		Line 1:
		+
	==F17-aG lectin domain from Escherichia coli in complex with N-acetyl-glucosamine==		==F17-aG lectin domain from Escherichia coli in complex with N-acetyl-glucosamine==
	<StructureSection load='1o9w' size='340' side='right' caption='[[1o9w]], [[Resolution\|resolution]] 1.65Å' scene=''>		<StructureSection load='1o9w' size='340' side='right' caption='[[1o9w]], [[Resolution\|resolution]] 1.65Å' scene=''>
Line 5:		Line 6:
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1o9v\|1o9v]], [[1o9z\|1o9z]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1o9v\|1o9v]], [[1o9z\|1o9z]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1o9w FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1o9w OCA], [http://pdbe.org/1o9w PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1o9w RCSB], [http://www.ebi.ac.uk/pdbsum/1o9w PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1o9w FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1o9w OCA], [http://pdbe.org/1o9w PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1o9w RCSB], [http://www.ebi.ac.uk/pdbsum/1o9w PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1o9w ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==

OCA at 15:03, 10 September 2015

OCA — Thu, 10 Sep 2015 15:03:45 GMT

←Older revision		Revision as of 15:03, 10 September 2015
Line 2:		Line 2:
	<StructureSection load='1o9w' size='340' side='right' caption='[[1o9w]], [[Resolution\|resolution]] 1.65Å' scene=''>		<StructureSection load='1o9w' size='340' side='right' caption='[[1o9w]], [[Resolution\|resolution]] 1.65Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1o9w]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Escherichia_coli Escherichia~~ coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1O9W OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1O9W FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1o9w]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1O9W OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1O9W FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1o9v\|1o9v]], [[1o9z\|1o9z]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1o9v\|1o9v]], [[1o9z\|1o9z]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1o9w FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1o9w OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1o9w RCSB], [http://www.ebi.ac.uk/pdbsum/1o9w PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1o9w FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1o9w OCA], [http://pdbe.org/1o9w PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1o9w RCSB], [http://www.ebi.ac.uk/pdbsum/1o9w PDBsum]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 17:		Line 17:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 1o9w" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Escherichia~~ coli]]	+	[[Category: Bacillus coli migula 1895]]
	[[Category: Bouckaert, J]]		[[Category: Bouckaert, J]]
	[[Category: Brosens, E]]		[[Category: Brosens, E]]

OCA at 01:54, 25 December 2014

OCA — Thu, 25 Dec 2014 01:54:39 GMT

←Older revision		Revision as of 01:54, 25 December 2014
Line 7:		Line 7:
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1o9w FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1o9w OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1o9w RCSB], [http://www.ebi.ac.uk/pdbsum/1o9w PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1o9w FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1o9w OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1o9w RCSB], [http://www.ebi.ac.uk/pdbsum/1o9w PDBsum]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/F17AG_ECOLX F17AG_ECOLX]] Essential fimbrial adhesion factor that mediates binding to N-acetylglucosamine-containing receptors in the host intestinal microvilli, leading to colonization of the intestinal tissue, and diarrhea or septicemia. Also confers adhesiveness to laminin and basement membranes.
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==

OCA at 05:35, 22 December 2014

OCA — Mon, 22 Dec 2014 05:35:10 GMT

←Older revision		Revision as of 05:35, 22 December 2014
Line 1:		Line 1:
-	~~{{STRUCTURE_1o9w\| PDB=1o9w \| SCENE= }}~~	+	==F17-aG lectin domain from Escherichia coli in complex with N-acetyl-glucosamine==
-	===F17-aG lectin domain from Escherichia coli in complex with N-acetyl-glucosamine===	+	<StructureSection load='1o9w' size='340' side='right' caption='[[1o9w]], [[Resolution\|resolution]] 1.65Å' scene=''>
-	~~{{ABSTRACT_PUBMED_12864853}}~~	+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[1o9w]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1O9W OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1O9W FirstGlance]. <br>
		+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
		+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1o9v\|1o9v]], [[1o9z\|1o9z]]</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1o9w FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1o9w OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1o9w RCSB], [http://www.ebi.ac.uk/pdbsum/1o9w PDBsum]</span></td></tr>
		+	</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	The F17-G adhesin at the tip of flexible F17 fimbriae of enterotoxigenic Escherichia coli mediates binding to N-acetyl-beta-D-glucosamine-presenting receptors on the microvilli of the intestinal epithelium of ruminants. We report the 1.7 A resolution crystal structure of the lectin domain of F17-G, both free and in complex with N-acetylglucosamine. The monosaccharide is bound on the side of the ellipsoid-shaped protein in a conserved site around which all natural variations of F17-G are clustered. A model is proposed for the interaction between F17-fimbriated E. coli and microvilli with enhanced affinity compared with the binding constant we determined for F17-G binding to N-acetylglucosamine (0.85 mM-1). Unexpectedly, the F17-G structure reveals that the lectin domains of the F17-G, PapGII and FimH fimbrial adhesins all share the immunoglobulin-like fold of the structural components (pilins) of their fimbriae, despite lack of any sequence identity. Fold comparisons with pilin and chaperone structures of the chaperone/usher pathway highlight the central role of the C-terminal beta-strand G of the immunoglobulin-like fold and provides new insights into pilus assembly, function and adhesion.

-	~~==Function==~~	+	The fimbrial adhesin F17-G of enterotoxigenic Escherichia coli has an immunoglobulin-like lectin domain that binds N-acetylglucosamine.,Buts L, Bouckaert J, De Genst E, Loris R, Oscarson S, Lahmann M, Messens J, Brosens E, Wyns L, De Greve H Mol Microbiol. 2003 Aug;49(3):705-15. PMID:12864853<ref>PMID:12864853</ref>
-	~~[[http://www.uniprot.org/uniprot/F17AG_ECOLX F17AG_ECOLX]] Essential~~ fimbrial ~~adhesion factor~~ that ~~mediates binding to~~ N-acetylglucosamine~~-containing receptors in the host intestinal microvilli~~, ~~leading to colonization of the intestinal tissue~~, ~~and diarrhea or septicemia~~. ~~Also confers adhesiveness to laminin and basement membranes~~.	+

-	~~==About this Structure==~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	~~[[1o9w]] is~~ a ~~1 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Escherichia_coli Escherichia coli]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=1O9W OCA].~~	+	</div>
-		+	== References ==
-	==~~Reference~~==	+	<references/>
-	~~<ref group="xtra">PMID:012864853</ref>~~<references ~~group="xtra"~~/><~~references~~/>	+	__TOC__
		+	</StructureSection>
	[[Category: Escherichia coli]]		[[Category: Escherichia coli]]
-	[[Category: Bouckaert, J.]]	+	[[Category: Bouckaert, J]]
-	[[Category: Brosens, E.]]	+	[[Category: Brosens, E]]
-	[[Category: Buts, L.]]	+	[[Category: Buts, L]]
-	[[Category: Genst, E De.]]	+	[[Category: Genst, E De]]
-	[[Category: Greve, H De.]]	+	[[Category: Greve, H De]]
-	[[Category: Lahmann, M.]]	+	[[Category: Lahmann, M]]
-	[[Category: Loris, R.]]	+	[[Category: Loris, R]]
-	[[Category: Messens, J.]]	+	[[Category: Messens, J]]
-	[[Category: Oscarson, S.]]	+	[[Category: Oscarson, S]]
-	[[Category: Wyns, L.]]	+	[[Category: Wyns, L]]
	[[Category: Bacterial adhesin]]		[[Category: Bacterial adhesin]]
	[[Category: Bacterial attachment]]		[[Category: Bacterial attachment]]

OCA at 10:31, 16 April 2014

OCA — Wed, 16 Apr 2014 10:31:55 GMT

←Older revision		Revision as of 10:31, 16 April 2014
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-	[[Image:1o9w.png\|left\|200px]]
-
-	<!--
-	The line below this paragraph, containing "STRUCTURE_1o9w", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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	{{STRUCTURE_1o9w\| PDB=1o9w \| SCENE= }}		{{STRUCTURE_1o9w\| PDB=1o9w \| SCENE= }}
-
	===F17-aG lectin domain from Escherichia coli in complex with N-acetyl-glucosamine===		===F17-aG lectin domain from Escherichia coli in complex with N-acetyl-glucosamine===
		+	{{ABSTRACT_PUBMED_12864853}}

-		+	==Function==
-	~~<!--~~	+	[[http://www.uniprot.org/uniprot/F17AG_ECOLX F17AG_ECOLX]] Essential fimbrial adhesion factor that mediates binding to N-acetylglucosamine-containing receptors in the host intestinal microvilli, leading to colonization of the intestinal tissue, and diarrhea or septicemia. Also confers adhesiveness to laminin and basement membranes.
-	~~The line below this paragraph, {{ABSTRACT_PUBMED_12864853}}, adds the Publication Abstract to the page~~	+
-	~~(as it appears on PubMed at~~ http://www.~~pubmed~~.~~gov)~~, ~~where 12864853 is~~ the ~~PubMed ID number~~.	+
-	~~-->~~	+
-	~~{{ABSTRACT_PUBMED_12864853}}~~	+

	==About this Structure==		==About this Structure==
Line 22:		Line 10:

	==Reference==		==Reference==
-	<ref group="xtra">PMID:012864853</ref><~~ref~~ group="xtra"~~>PMID:012777763<~~/~~ref><ref group="xtra">PMID:001675211</ref~~><references ~~group="xtra"~~/>	+	<ref group="xtra">PMID:012864853</ref><references group="xtra"/><references/>
	[[Category: Escherichia coli]]		[[Category: Escherichia coli]]
	[[Category: Bouckaert, J.]]		[[Category: Bouckaert, J.]]

OCA at 09:50, 18 January 2012

OCA — Wed, 18 Jan 2012 09:50:36 GMT

←Older revision		Revision as of 09:50, 18 January 2012
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	{{STRUCTURE_1o9w\| PDB=1o9w \| SCENE= }}		{{STRUCTURE_1o9w\| PDB=1o9w \| SCENE= }}

-	===F17-~~AG LECTIN DOMAIN FROM ESCHERICHIA COLI IN COMPLEX WITH~~ N-~~ACETYL~~-~~GLUCOSAMINE~~===	+	===F17-aG lectin domain from Escherichia coli in complex with N-acetyl-glucosamine===


Line 22:		Line 22:

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~12864853~~</ref><ref group="xtra">PMID:~~12777763~~</ref><ref group="xtra">PMID:~~1675211~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:012864853</ref><ref group="xtra">PMID:012777763</ref><ref group="xtra">PMID:001675211</ref><references group="xtra"/>
	[[Category: Escherichia coli]]		[[Category: Escherichia coli]]
	[[Category: Bouckaert, J.]]		[[Category: Bouckaert, J.]]
Line 37:		Line 37:
	[[Category: Bacterial attachment]]		[[Category: Bacterial attachment]]
	[[Category: Immunoglobulin fold]]		[[Category: Immunoglobulin fold]]
-	[[Category: ~~Lectin~~]]	+	[[Category: Sugar binding protein]]
-	[[Category: ~~Pathogenesis~~]]	+	[[Category: Sugar binding protein pathogenesis]]