1obr - Revision history

OCA at 06:31, 9 August 2023

OCA — Wed, 09 Aug 2023 06:31:18 GMT

←Older revision		Revision as of 06:31, 9 August 2023
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	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1obr]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermoactinomyces_vulgaris Thermoactinomyces vulgaris]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1OBR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1OBR FirstGlance]. <br>		<table><tr><td colspan='2'>[[1obr]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermoactinomyces_vulgaris Thermoactinomyces vulgaris]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1OBR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1OBR FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene~~></td></tr>~~	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.3Å</td></tr>
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Carboxypeptidase_T Carboxypeptidase T], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.17.18 3.4.17.18] </span></td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1obr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1obr OCA], [https://pdbe.org/1obr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1obr RCSB], [https://www.ebi.ac.uk/pdbsum/1obr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1obr ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1obr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1obr OCA], [https://pdbe.org/1obr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1obr RCSB], [https://www.ebi.ac.uk/pdbsum/1obr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1obr ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[https://www.uniprot.org/uniprot/CBPT_THEVU CBPT_THEVU]] Able to split off hydrophobic and basic amino acids with comparable efficiency.	+	[https://www.uniprot.org/uniprot/CBPT_THEVU CBPT_THEVU] Able to split off hydrophobic and basic amino acids with comparable efficiency.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Carboxypeptidase T]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
	[[Category: Thermoactinomyces vulgaris]]		[[Category: Thermoactinomyces vulgaris]]
-	[[Category: Obmolova, G]]	+	[[Category: Obmolova G]]
-	[[Category: Osterman, A]]	+	[[Category: Osterman A]]
-	[[Category: Polyakov, K]]	+	[[Category: Polyakov K]]
-	[[Category: Teplyakov, A]]	+	[[Category: Teplyakov A]]
-	~~[[Category: Carboxypeptidase]]~~	+
-	~~[[Category: Hydrolase~~]]	+

OCA at 07:17, 22 September 2021

OCA — Wed, 22 Sep 2021 07:17:16 GMT

←Older revision		Revision as of 07:17, 22 September 2021
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	<StructureSection load='1obr' size='340' side='right'caption='[[1obr]], [[Resolution\|resolution]] 2.30Å' scene=''>		<StructureSection load='1obr' size='340' side='right'caption='[[1obr]], [[Resolution\|resolution]] 2.30Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1obr]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Thermoactinomyces_vulgaris Thermoactinomyces vulgaris]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1OBR OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1OBR FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1obr]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermoactinomyces_vulgaris Thermoactinomyces vulgaris]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1OBR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1OBR FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://en.wikipedia.org/wiki/Carboxypeptidase_T Carboxypeptidase T], with EC number [~~http~~://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.17.18 3.4.17.18] </span></td></tr>	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Carboxypeptidase_T Carboxypeptidase T], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.17.18 3.4.17.18] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1obr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1obr OCA], [~~http~~://pdbe.org/1obr PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=1obr RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/1obr PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=1obr ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1obr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1obr OCA], [https://pdbe.org/1obr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1obr RCSB], [https://www.ebi.ac.uk/pdbsum/1obr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1obr ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[~~http~~://www.uniprot.org/uniprot/CBPT_THEVU CBPT_THEVU]] Able to split off hydrophobic and basic amino acids with comparable efficiency.	+	[[https://www.uniprot.org/uniprot/CBPT_THEVU CBPT_THEVU]] Able to split off hydrophobic and basic amino acids with comparable efficiency.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]

OCA at 14:08, 18 December 2019

OCA — Wed, 18 Dec 2019 14:08:31 GMT

←Older revision		Revision as of 14:08, 18 December 2019
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	==CARBOXYPEPTIDASE T==		==CARBOXYPEPTIDASE T==
-	<StructureSection load='1obr' size='340' side='right' caption='[[1obr]], [[Resolution\|resolution]] 2.30Å' scene=''>	+	<StructureSection load='1obr' size='340' side='right'caption='[[1obr]], [[Resolution\|resolution]] 2.30Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1obr]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Thermoactinomyces_vulgaris Thermoactinomyces vulgaris]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1OBR OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1OBR FirstGlance]. <br>		<table><tr><td colspan='2'>[[1obr]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Thermoactinomyces_vulgaris Thermoactinomyces vulgaris]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1OBR OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1OBR FirstGlance]. <br>
Line 31:		Line 31:

	==See Also==		==See Also==
-	*[[Carboxypeptidase\|Carboxypeptidase]]	+	*[[Carboxypeptidase 3D structures\|Carboxypeptidase 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
Line 37:		Line 37:
	</StructureSection>		</StructureSection>
	[[Category: Carboxypeptidase T]]		[[Category: Carboxypeptidase T]]
		+	[[Category: Large Structures]]
	[[Category: Thermoactinomyces vulgaris]]		[[Category: Thermoactinomyces vulgaris]]
	[[Category: Obmolova, G]]		[[Category: Obmolova, G]]

OCA at 06:41, 14 March 2018

OCA — Wed, 14 Mar 2018 06:41:19 GMT

←Older revision		Revision as of 06:41, 14 March 2018
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	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ob/1obr_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ob/1obr_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
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	</div>		</div>
	<div class="pdbe-citations 1obr" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 1obr" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[Carboxypeptidase\|Carboxypeptidase]]
	== References ==		== References ==
	<references/>		<references/>

OCA at 09:46, 1 November 2017

OCA — Wed, 01 Nov 2017 09:46:35 GMT

←Older revision		Revision as of 09:46, 1 November 2017
Line 1:		Line 1:
		+
	==CARBOXYPEPTIDASE T==		==CARBOXYPEPTIDASE T==
	<StructureSection load='1obr' size='340' side='right' caption='[[1obr]], [[Resolution\|resolution]] 2.30Å' scene=''>		<StructureSection load='1obr' size='340' side='right' caption='[[1obr]], [[Resolution\|resolution]] 2.30Å' scene=''>
Line 5:		Line 6:
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Carboxypeptidase_T Carboxypeptidase T], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.17.18 3.4.17.18] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Carboxypeptidase_T Carboxypeptidase T], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.17.18 3.4.17.18] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1obr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1obr OCA], [http://pdbe.org/1obr PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1obr RCSB], [http://www.ebi.ac.uk/pdbsum/1obr PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1obr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1obr OCA], [http://pdbe.org/1obr PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1obr RCSB], [http://www.ebi.ac.uk/pdbsum/1obr PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1obr ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
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	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1obr ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
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	</div>		</div>
	<div class="pdbe-citations 1obr" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 1obr" style="background-color:#fffaf0;"></div>
-
-	==See Also==
-	*[[Carboxypeptidase\|Carboxypeptidase]]
	== References ==		== References ==
	<references/>		<references/>

OCA at 11:30, 11 September 2015

OCA — Fri, 11 Sep 2015 11:30:24 GMT

←Older revision		Revision as of 11:30, 11 September 2015
Line 5:		Line 5:
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Carboxypeptidase_T Carboxypeptidase T], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.17.18 3.4.17.18] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Carboxypeptidase_T Carboxypeptidase T], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.17.18 3.4.17.18] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1obr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1obr OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1obr RCSB], [http://www.ebi.ac.uk/pdbsum/1obr PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1obr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1obr OCA], [http://pdbe.org/1obr PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1obr RCSB], [http://www.ebi.ac.uk/pdbsum/1obr PDBsum]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 27:		Line 27:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 1obr" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==

OCA at 15:52, 25 December 2014

OCA — Thu, 25 Dec 2014 15:52:07 GMT

←Older revision		Revision as of 15:52, 25 December 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1obr]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Thermoactinomyces_vulgaris Thermoactinomyces vulgaris]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1OBR OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1OBR FirstGlance]. <br>		<table><tr><td colspan='2'>[[1obr]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Thermoactinomyces_vulgaris Thermoactinomyces vulgaris]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1OBR OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1OBR FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene><br>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
-	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Carboxypeptidase_T Carboxypeptidase T], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.17.18 3.4.17.18] </span></td></tr>	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Carboxypeptidase_T Carboxypeptidase T], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.17.18 3.4.17.18] </span></td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1obr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1obr OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1obr RCSB], [http://www.ebi.ac.uk/pdbsum/1obr PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1obr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1obr OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1obr RCSB], [http://www.ebi.ac.uk/pdbsum/1obr PDBsum]</span></td></tr>
-	<table>	+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/CBPT_THEVU CBPT_THEVU]] Able to split off hydrophobic and basic amino acids with comparable efficiency.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
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	[[Category: Carboxypeptidase T]]		[[Category: Carboxypeptidase T]]
	[[Category: Thermoactinomyces vulgaris]]		[[Category: Thermoactinomyces vulgaris]]
-	[[Category: Obmolova, G.]]	+	[[Category: Obmolova, G]]
-	[[Category: Osterman, A.]]	+	[[Category: Osterman, A]]
-	[[Category: Polyakov, K.]]	+	[[Category: Polyakov, K]]
-	[[Category: Teplyakov, A.]]	+	[[Category: Teplyakov, A]]
	[[Category: Carboxypeptidase]]		[[Category: Carboxypeptidase]]
	[[Category: Hydrolase]]		[[Category: Hydrolase]]

OCA at 13:56, 28 September 2014

OCA — Sun, 28 Sep 2014 13:56:25 GMT

←Older revision		Revision as of 13:56, 28 September 2014
Line 1:		Line 1:
-	[[~~Image~~:1obr.~~png\|left~~\|200px]]	+	==CARBOXYPEPTIDASE T==
		+	<StructureSection load='1obr' size='340' side='right' caption='[[1obr]], [[Resolution\|resolution]] 2.30Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[1obr]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Thermoactinomyces_vulgaris Thermoactinomyces vulgaris]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1OBR OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1OBR FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene><br>
		+	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Carboxypeptidase_T Carboxypeptidase T], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.17.18 3.4.17.18] </span></td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1obr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1obr OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1obr RCSB], [http://www.ebi.ac.uk/pdbsum/1obr PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ob/1obr_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	The crystal structure of carboxypeptidase T from Thermoactinomyces vulgaris has been determined at 0.235-nm resolution by X-ray diffraction. Carboxypeptidase T is a remote homologue of mammalian Zn-carboxypeptidases. In spite of the low degree of amino acid sequence identity, the three-dimensional structure of carboxypeptidase T is very similar to that of pancreatic carboxypeptidases A and B. The core of the protein molecule is formed by an eight-stranded mixed beta sheet. The active site is located at the C-edge of the central (parallel) part of the beta sheet. The structural organization of the active centre appears to be essentially the same in the three carboxypeptidases. Amino acid residues directly involved in catalysis and binding of the C-terminal carboxyl of a substrate are strictly conserved. This suggests that the catalytic mechanism proposed for the pancreatic enzymes is applicable to carboxypeptidase T and to the whole family of Zn-carboxypeptidases. Comparison of the amino acid replacements at the primary specificity pocket of carboxypeptidases A, B and T provides an explanation of the unusual 'A+B' type of specificity of carboxypeptidase T. Four calcium-binding sites localized in the crystal structure of carboxypeptidase T could account for the high thermostability of the protein.

-	~~{{STRUCTURE_1obr\| PDB=1obr \| SCENE= }}~~	+	Crystal structure of carboxypeptidase T from Thermoactinomyces vulgaris.,Teplyakov A, Polyakov K, Obmolova G, Strokopytov B, Kuranova I, Osterman A, Grishin N, Smulevitch S, Zagnitko O, Galperina O, et al. Eur J Biochem. 1992 Sep 1;208(2):281-8. PMID:1521526<ref>PMID:1521526</ref>

-	~~===CARBOXYPEPTIDASE T===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_1521526}}~~	+
-		+
-	~~==About this Structure==~~	+
-	~~[[1obr]] is~~ a ~~1 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Thermoactinomyces_vulgaris Thermoactinomyces vulgaris]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=1OBR OCA].~~	+

	==See Also==		==See Also==
	*[[Carboxypeptidase\|Carboxypeptidase]]		*[[Carboxypeptidase\|Carboxypeptidase]]
-		+	== References ==
-	==~~Reference~~==	+	<references/>
-	<~~ref group="xtra">PMID:001521526<~~/~~ref~~><~~references group="xtra"~~/>	+	__TOC__
		+	</StructureSection>
	[[Category: Carboxypeptidase T]]		[[Category: Carboxypeptidase T]]
	[[Category: Thermoactinomyces vulgaris]]		[[Category: Thermoactinomyces vulgaris]]

OCA at 18:33, 20 October 2012

OCA — Sat, 20 Oct 2012 18:33:58 GMT

←Older revision		Revision as of 18:33, 20 October 2012
Line 8:		Line 8:

	==About this Structure==		==About this Structure==
-	[[1obr]] is a 1 chain structure ~~of [[Carboxypeptidase]]~~ with sequence from [http://en.wikipedia.org/wiki/Thermoactinomyces_vulgaris Thermoactinomyces vulgaris]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1OBR OCA].	+	[[1obr]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Thermoactinomyces_vulgaris Thermoactinomyces vulgaris]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1OBR OCA].

	==See Also==		==See Also==

OCA at 04:29, 27 July 2012

OCA — Fri, 27 Jul 2012 04:29:16 GMT

←Older revision		Revision as of 04:29, 27 July 2012
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	[[Image:1obr.png\|left\|200px]]		[[Image:1obr.png\|left\|200px]]

-	<!--
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	{{STRUCTURE_1obr\| PDB=1obr \| SCENE= }}		{{STRUCTURE_1obr\| PDB=1obr \| SCENE= }}

	===CARBOXYPEPTIDASE T===		===CARBOXYPEPTIDASE T===

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	==See Also==		==See Also==
-	*[[Carboxypeptidase]]	+	*[[Carboxypeptidase\|Carboxypeptidase]]

	==Reference==		==Reference==