1ocq - Revision history

OCA at 12:35, 13 December 2023

OCA — Wed, 13 Dec 2023 12:35:29 GMT

←Older revision		Revision as of 12:35, 13 December 2023
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	<StructureSection load='1ocq' size='340' side='right'caption='[[1ocq]], [[Resolution\|resolution]] 1.08Å' scene=''>		<StructureSection load='1ocq' size='340' side='right'caption='[[1ocq]], [[Resolution\|resolution]] 1.08Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1ocq]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Atcc_700163 Atcc 700163~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1OCQ OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=1OCQ FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1ocq]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Salipaludibacillus_agaradhaerens Salipaludibacillus agaradhaerens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1OCQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1OCQ FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BGC:BETA-D-GLUCOSE'>BGC</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=IFM:5-HYDROXYMETHYL-3,4-DIHYDROXYPIPERIDINE'>IFM</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene~~></td></tr>~~	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.08Å</td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1a3h\|1a3h]], [[1e5j\|1e5j]], [[1h11\|1h11]], [[1h2j\|1h2j]], [[1h5v\|1h5v]], [[1hf6\|1hf6]], [[1qhz\|1qhz]], [[1qi0\|1qi0]], [[1qi2\|1qi2]], [[2a3h\|2a3h]], [[3a3h\|3a3h]], [[4a3h\|4a3h]], [[5a3h\|5a3h]], [[6a3h\|6a3h]], [[7a3h\|7a3h]], [[8a3h\|8a3h]]</div></td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BGC:BETA-D-GLUCOSE'>BGC</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=IFM:5-HYDROXYMETHYL-3,4-DIHYDROXYPIPERIDINE'>IFM</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Cellulase Cellulase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.4 3.2.1.4] </span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ocq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ocq OCA], [https://pdbe.org/1ocq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ocq RCSB], [https://www.ebi.ac.uk/pdbsum/1ocq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ocq ProSAT]</span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=1ocq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ocq OCA], [~~http~~://pdbe.org/1ocq PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=1ocq RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/1ocq PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=1ocq ProSAT]</span></td></tr>	+
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/GUN5_SALAG GUN5_SALAG]
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Atcc 700163]]
-	[[Category: Cellulase]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Davies~~, G J~~]]	+	[[Category: Salipaludibacillus agaradhaerens]]
-	[[Category: Macdonald, J]]	+	[[Category: Davies GJ]]
-	[[Category: Stick~~, R V~~]]	+	[[Category: Macdonald J]]
-	[[Category: Varrot, A]]	+	[[Category: Stick RV]]
-	[[Category: Withers~~, S G]]~~	+	[[Category: Varrot A]]
-	~~[[Category: Cellulose degradation]]~~	+	[[Category: Withers SG]]
-	~~[[Category: Endoglucanase]]~~	+
-	~~[[Category: Glycosidase]]~~	+
-	~~[[Category: Hydrolase~~]]	+

OCA at 07:11, 9 December 2020

OCA — Wed, 09 Dec 2020 07:11:24 GMT

←Older revision		Revision as of 07:11, 9 December 2020
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	==COMPLEX OF THE ENDOGLUCANASE CEL5A FROM BACILLUS AGARADHEARANS AT 1.08 ANGSTROM RESOLUTION with cellobio-derived isofagomine==		==COMPLEX OF THE ENDOGLUCANASE CEL5A FROM BACILLUS AGARADHEARANS AT 1.08 ANGSTROM RESOLUTION with cellobio-derived isofagomine==
-	<StructureSection load='1ocq' size='340' side='right' caption='[[1ocq]], [[Resolution\|resolution]] 1.08Å' scene=''>	+	<StructureSection load='1ocq' size='340' side='right'caption='[[1ocq]], [[Resolution\|resolution]] 1.08Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1ocq]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_700163 Atcc 700163]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1OCQ OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1OCQ FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1ocq]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_700163 Atcc 700163]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1OCQ OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=1OCQ FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BGC:BETA-D-GLUCOSE'>BGC</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=IFM:5-HYDROXYMETHYL-3,4-DIHYDROXYPIPERIDINE'>IFM</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BGC:BETA-D-GLUCOSE'>BGC</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=IFM:5-HYDROXYMETHYL-3,4-DIHYDROXYPIPERIDINE'>IFM</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1a3h\|1a3h]], [[1e5j\|1e5j]], [[1h11\|1h11]], [[1h2j\|1h2j]], [[1h5v\|1h5v]], [[1hf6\|1hf6]], [[1qhz\|1qhz]], [[1qi0\|1qi0]], [[1qi2\|1qi2]], [[2a3h\|2a3h]], [[3a3h\|3a3h]], [[4a3h\|4a3h]], [[5a3h\|5a3h]], [[6a3h\|6a3h]], [[7a3h\|7a3h]], [[8a3h\|8a3h]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1a3h\|1a3h]], [[1e5j\|1e5j]], [[1h11\|1h11]], [[1h2j\|1h2j]], [[1h5v\|1h5v]], [[1hf6\|1hf6]], [[1qhz\|1qhz]], [[1qi0\|1qi0]], [[1qi2\|1qi2]], [[2a3h\|2a3h]], [[3a3h\|3a3h]], [[4a3h\|4a3h]], [[5a3h\|5a3h]], [[6a3h\|6a3h]], [[7a3h\|7a3h]], [[8a3h\|8a3h]]</div></td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Cellulase Cellulase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.4 3.2.1.4] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Cellulase Cellulase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.4 3.2.1.4] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1ocq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ocq OCA], [http://pdbe.org/1ocq PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1ocq RCSB], [http://www.ebi.ac.uk/pdbsum/1ocq PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1ocq ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=1ocq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ocq OCA], [http://pdbe.org/1ocq PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1ocq RCSB], [http://www.ebi.ac.uk/pdbsum/1ocq PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1ocq ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
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	==See Also==		==See Also==
-	*[[Glucanase\|Glucanase]]	+	*[[Glucanase 3D structures\|Glucanase 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
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	[[Category: Atcc 700163]]		[[Category: Atcc 700163]]
	[[Category: Cellulase]]		[[Category: Cellulase]]
		+	[[Category: Large Structures]]
	[[Category: Davies, G J]]		[[Category: Davies, G J]]
	[[Category: Macdonald, J]]		[[Category: Macdonald, J]]

OCA at 07:42, 6 March 2019

OCA — Wed, 06 Mar 2019 07:42:11 GMT

←Older revision		Revision as of 07:42, 6 March 2019
Line 1:		Line 1:

	==COMPLEX OF THE ENDOGLUCANASE CEL5A FROM BACILLUS AGARADHEARANS AT 1.08 ANGSTROM RESOLUTION with cellobio-derived isofagomine==		==COMPLEX OF THE ENDOGLUCANASE CEL5A FROM BACILLUS AGARADHEARANS AT 1.08 ANGSTROM RESOLUTION with cellobio-derived isofagomine==
-	<StructureSection load='1ocq' size='340' side='right' caption='[[1ocq]], [[Resolution\|resolution]] 1.08Å' scene=''>	+	<StructureSection load='1ocq' size='340' side='right' caption='[[1ocq]], [[Resolution\|resolution]] 1.08Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1ocq]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_700163 Atcc 700163]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1OCQ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1OCQ FirstGlance]. <br>		<table><tr><td colspan='2'>[[1ocq]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_700163 Atcc 700163]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1OCQ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1OCQ FirstGlance]. <br>

OCA at 09:46, 30 January 2019

OCA — Wed, 30 Jan 2019 09:46:05 GMT

←Older revision		Revision as of 09:46, 30 January 2019
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	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/oc/1ocq_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/oc/1ocq_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>

OCA at 14:19, 27 April 2017

OCA — Thu, 27 Apr 2017 14:19:24 GMT

←Older revision		Revision as of 14:19, 27 April 2017
Line 1:		Line 1:
		+
	==COMPLEX OF THE ENDOGLUCANASE CEL5A FROM BACILLUS AGARADHEARANS AT 1.08 ANGSTROM RESOLUTION with cellobio-derived isofagomine==		==COMPLEX OF THE ENDOGLUCANASE CEL5A FROM BACILLUS AGARADHEARANS AT 1.08 ANGSTROM RESOLUTION with cellobio-derived isofagomine==
	<StructureSection load='1ocq' size='340' side='right' caption='[[1ocq]], [[Resolution\|resolution]] 1.08Å' scene=''>		<StructureSection load='1ocq' size='340' side='right' caption='[[1ocq]], [[Resolution\|resolution]] 1.08Å' scene=''>
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	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1a3h\|1a3h]], [[1e5j\|1e5j]], [[1h11\|1h11]], [[1h2j\|1h2j]], [[1h5v\|1h5v]], [[1hf6\|1hf6]], [[1qhz\|1qhz]], [[1qi0\|1qi0]], [[1qi2\|1qi2]], [[2a3h\|2a3h]], [[3a3h\|3a3h]], [[4a3h\|4a3h]], [[5a3h\|5a3h]], [[6a3h\|6a3h]], [[7a3h\|7a3h]], [[8a3h\|8a3h]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1a3h\|1a3h]], [[1e5j\|1e5j]], [[1h11\|1h11]], [[1h2j\|1h2j]], [[1h5v\|1h5v]], [[1hf6\|1hf6]], [[1qhz\|1qhz]], [[1qi0\|1qi0]], [[1qi2\|1qi2]], [[2a3h\|2a3h]], [[3a3h\|3a3h]], [[4a3h\|4a3h]], [[5a3h\|5a3h]], [[6a3h\|6a3h]], [[7a3h\|7a3h]], [[8a3h\|8a3h]]</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Cellulase Cellulase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.4 3.2.1.4] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Cellulase Cellulase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.4 3.2.1.4] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ocq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ocq OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1ocq RCSB], [http://www.ebi.ac.uk/pdbsum/1ocq PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ocq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ocq OCA], [http://pdbe.org/1ocq PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1ocq RCSB], [http://www.ebi.ac.uk/pdbsum/1ocq PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1ocq ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
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	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1ocq ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
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	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 1ocq" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==

OCA at 08:15, 22 July 2015

OCA — Wed, 22 Jul 2015 08:15:37 GMT

←Older revision		Revision as of 08:15, 22 July 2015
Line 1:		Line 1:
-	==COMPLEX OF THE ENDOGLUCANASE CEL5A FROM BACILLUS AGARADHEARANS AT 1.08 ANGSTROM RESOLUTION ~~WITH CELLOBIO~~-~~DERIVED ISOFAGOMINE~~==	+	==COMPLEX OF THE ENDOGLUCANASE CEL5A FROM BACILLUS AGARADHEARANS AT 1.08 ANGSTROM RESOLUTION with cellobio-derived isofagomine==
	<StructureSection load='1ocq' size='340' side='right' caption='[[1ocq]], [[Resolution\|resolution]] 1.08Å' scene=''>		<StructureSection load='1ocq' size='340' side='right' caption='[[1ocq]], [[Resolution\|resolution]] 1.08Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1ocq]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Bacillus_agaradhaerens Bacillus agaradhaerens~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1OCQ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1OCQ FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1ocq]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_700163 Atcc 700163]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1OCQ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1OCQ FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BGC:BETA-D-GLUCOSE'>BGC</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=IFM:5-HYDROXYMETHYL-3,4-DIHYDROXYPIPERIDINE'>IFM</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BGC:BETA-D-GLUCOSE'>BGC</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=IFM:5-HYDROXYMETHYL-3,4-DIHYDROXYPIPERIDINE'>IFM</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1a3h\|1a3h]], [[1e5j\|1e5j]], [[1h11\|1h11]], [[1h2j\|1h2j]], [[1h5v\|1h5v]], [[1hf6\|1hf6]], [[1qhz\|1qhz]], [[1qi0\|1qi0]], [[1qi2\|1qi2]], [[2a3h\|2a3h]], [[3a3h\|3a3h]], [[4a3h\|4a3h]], [[5a3h\|5a3h]], [[6a3h\|6a3h]], [[7a3h\|7a3h]], [[8a3h\|8a3h]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1a3h\|1a3h]], [[1e5j\|1e5j]], [[1h11\|1h11]], [[1h2j\|1h2j]], [[1h5v\|1h5v]], [[1hf6\|1hf6]], [[1qhz\|1qhz]], [[1qi0\|1qi0]], [[1qi2\|1qi2]], [[2a3h\|2a3h]], [[3a3h\|3a3h]], [[4a3h\|4a3h]], [[5a3h\|5a3h]], [[6a3h\|6a3h]], [[7a3h\|7a3h]], [[8a3h\|8a3h]]</td></tr>
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Bacillus agaradhaerens~~]]	+	[[Category: Atcc 700163]]
	[[Category: Cellulase]]		[[Category: Cellulase]]
	[[Category: Davies, G J]]		[[Category: Davies, G J]]
-	[[Category: Macdonald, J M]]	+	[[Category: Macdonald, J]]
	[[Category: Stick, R V]]		[[Category: Stick, R V]]
	[[Category: Varrot, A]]		[[Category: Varrot, A]]

OCA at 16:23, 5 January 2015

OCA — Mon, 05 Jan 2015 16:23:58 GMT

←Older revision		Revision as of 16:23, 5 January 2015
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	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1ocq]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacillus_agaradhaerens Bacillus agaradhaerens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1OCQ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1OCQ FirstGlance]. <br>		<table><tr><td colspan='2'>[[1ocq]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacillus_agaradhaerens Bacillus agaradhaerens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1OCQ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1OCQ FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BGC:BETA-D-GLUCOSE'>BGC</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=IFM:5-HYDROXYMETHYL-3,4-DIHYDROXYPIPERIDINE'>IFM</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene><br>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BGC:BETA-D-GLUCOSE'>BGC</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=IFM:5-HYDROXYMETHYL-3,4-DIHYDROXYPIPERIDINE'>IFM</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1a3h\|1a3h]], [[1e5j\|1e5j]], [[1h11\|1h11]], [[1h2j\|1h2j]], [[1h5v\|1h5v]], [[1hf6\|1hf6]], [[1qhz\|1qhz]], [[1qi0\|1qi0]], [[1qi2\|1qi2]], [[2a3h\|2a3h]], [[3a3h\|3a3h]], [[4a3h\|4a3h]], [[5a3h\|5a3h]], [[6a3h\|6a3h]], [[7a3h\|7a3h]], [[8a3h\|8a3h]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1a3h\|1a3h]], [[1e5j\|1e5j]], [[1h11\|1h11]], [[1h2j\|1h2j]], [[1h5v\|1h5v]], [[1hf6\|1hf6]], [[1qhz\|1qhz]], [[1qi0\|1qi0]], [[1qi2\|1qi2]], [[2a3h\|2a3h]], [[3a3h\|3a3h]], [[4a3h\|4a3h]], [[5a3h\|5a3h]], [[6a3h\|6a3h]], [[7a3h\|7a3h]], [[8a3h\|8a3h]]</td></tr>
-	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Cellulase Cellulase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.4 3.2.1.4] </span></td></tr>	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Cellulase Cellulase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.4 3.2.1.4] </span></td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ocq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ocq OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1ocq RCSB], [http://www.ebi.ac.uk/pdbsum/1ocq PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ocq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ocq OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1ocq RCSB], [http://www.ebi.ac.uk/pdbsum/1ocq PDBsum]</span></td></tr>
-	<table>	+	</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
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	[[Category: Bacillus agaradhaerens]]		[[Category: Bacillus agaradhaerens]]
	[[Category: Cellulase]]		[[Category: Cellulase]]
-	[[Category: Davies, G J.]]	+	[[Category: Davies, G J]]
-	[[Category: Macdonald, J M.]]	+	[[Category: Macdonald, J M]]
-	[[Category: Stick, R V.]]	+	[[Category: Stick, R V]]
-	[[Category: Varrot, A.]]	+	[[Category: Varrot, A]]
-	[[Category: Withers, S G.]]	+	[[Category: Withers, S G]]
	[[Category: Cellulose degradation]]		[[Category: Cellulose degradation]]
	[[Category: Endoglucanase]]		[[Category: Endoglucanase]]
	[[Category: Glycosidase]]		[[Category: Glycosidase]]
	[[Category: Hydrolase]]		[[Category: Hydrolase]]

OCA at 14:50, 28 September 2014

OCA — Sun, 28 Sep 2014 14:50:26 GMT

←Older revision		Revision as of 14:50, 28 September 2014
Line 1:		Line 1:
-	[[~~Image:~~1ocq.~~png~~\|~~left~~\|200px]]	+	==COMPLEX OF THE ENDOGLUCANASE CEL5A FROM BACILLUS AGARADHEARANS AT 1.08 ANGSTROM RESOLUTION WITH CELLOBIO-DERIVED ISOFAGOMINE==
		+	<StructureSection load='1ocq' size='340' side='right' caption='[[1ocq]], [[Resolution\|resolution]] 1.08Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[1ocq]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacillus_agaradhaerens Bacillus agaradhaerens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1OCQ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1OCQ FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BGC:BETA-D-GLUCOSE'>BGC</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=IFM:5-HYDROXYMETHYL-3,4-DIHYDROXYPIPERIDINE'>IFM</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene><br>
		+	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1a3h\|1a3h]], [[1e5j\|1e5j]], [[1h11\|1h11]], [[1h2j\|1h2j]], [[1h5v\|1h5v]], [[1hf6\|1hf6]], [[1qhz\|1qhz]], [[1qi0\|1qi0]], [[1qi2\|1qi2]], [[2a3h\|2a3h]], [[3a3h\|3a3h]], [[4a3h\|4a3h]], [[5a3h\|5a3h]], [[6a3h\|6a3h]], [[7a3h\|7a3h]], [[8a3h\|8a3h]]</td></tr>
		+	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Cellulase Cellulase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.4 3.2.1.4] </span></td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ocq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ocq OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1ocq RCSB], [http://www.ebi.ac.uk/pdbsum/1ocq PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/oc/1ocq_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Glycosidases are some of the most ubiquitous enzyme in nature. Their biological significance, coupled to their enormous catalytic prowess derived from tight binding of the transition state, is reflected in their importance as therapeutic targets. Many glycosidase inhibitors are known. Imino sugars are often potent inhibitors, yet many facets of their mode of action, such as their degree, if any, of transition-state "mimicry" and their protonation state when bound to the target glycosidase remain unclear. Atomic resolution analysis of the endoglucanase, Cel5A, in complex with a cellobio-derived isofagomine in conjunction with the pH dependence of Ki and kcat/KM reveals that this compound binds as a protonated sugar. Surprisingly, both the enzymatic nucleophile and the acid/base are unprotonated in the complex.

-	~~{{STRUCTURE_1ocq\| PDB=1ocq \| SCENE= }}~~	+	Direct observation of the protonation state of an imino sugar glycosidase inhibitor upon binding.,Varrot A, Tarling CA, Macdonald JM, Stick RV, Zechel DL, Withers SG, Davies GJ J Am Chem Soc. 2003 Jun 25;125(25):7496-7. PMID:12812472<ref>PMID:12812472</ref>

-	~~===COMPLEX OF THE ENDOGLUCANASE CEL5A FROM BACILLUS AGARADHEARANS AT 1.08 ANGSTROM RESOLUTION WITH CELLOBIO-DERIVED ISOFAGOMINE===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_12812472}}~~	+
-		+
-	~~==About this Structure==~~	+
-	~~[[1ocq]] is~~ a ~~1 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Bacillus_agaradhaerens Bacillus agaradhaerens]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=1OCQ OCA].~~	+

	==See Also==		==See Also==
	*[[Glucanase\|Glucanase]]		*[[Glucanase\|Glucanase]]
-		+	== References ==
-	==~~Reference~~==	+	<references/>
-	<~~ref group="xtra">PMID:012812472<~~/~~ref~~><~~references group="xtra"~~/>	+	__TOC__
		+	</StructureSection>
	[[Category: Bacillus agaradhaerens]]		[[Category: Bacillus agaradhaerens]]
	[[Category: Cellulase]]		[[Category: Cellulase]]

OCA at 21:07, 20 October 2012

OCA — Sat, 20 Oct 2012 21:07:58 GMT

←Older revision		Revision as of 21:07, 20 October 2012
Line 8:		Line 8:

	==About this Structure==		==About this Structure==
-	[[1ocq]] is a 1 chain structure ~~of [[Glucanase]]~~ with sequence from [http://en.wikipedia.org/wiki/Bacillus_agaradhaerens Bacillus agaradhaerens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1OCQ OCA].	+	[[1ocq]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacillus_agaradhaerens Bacillus agaradhaerens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1OCQ OCA].

	==See Also==		==See Also==

OCA: Protected "1ocq" [edit=sysop:move=sysop]

OCA — Fri, 27 Jul 2012 12:40:57 GMT

Protected "1ocq" [edit=sysop:move=sysop]

←Older revision

Revision as of 12:40, 27 July 2012