1otm - Revision history

OCA at 09:32, 16 August 2023

OCA — Wed, 16 Aug 2023 09:32:02 GMT

←Older revision		Revision as of 09:32, 16 August 2023
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	<StructureSection load='1otm' size='340' side='right'caption='[[1otm]], [[Resolution\|resolution]] 1.93Å' scene=''>		<StructureSection load='1otm' size='340' side='right'caption='[[1otm]], [[Resolution\|resolution]] 1.93Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1otm]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/~~"bacterium_monocytogenes_hominis"_nyfeldt_1932 "bacterium~~ monocytogenes ~~hominis" nyfeldt 1932~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1OTM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1OTM FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1otm]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Listeria_monocytogenes Listeria monocytogenes]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1OTM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1OTM FirstGlance]. <br>
-	</td></tr><tr id='~~related~~'><td class="sblockLbl"><b>[[~~Related_structure~~\|~~Related~~:]]</b></td><td class="sblockDat">~~<div style='overflow: auto; max~~-~~height: 3em;'>~~[[~~1d0b~~\|~~1d0b~~]]~~</div>~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.93Å</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1otm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1otm OCA], [https://pdbe.org/1otm PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1otm RCSB], [https://www.ebi.ac.uk/pdbsum/1otm PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1otm ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1otm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1otm OCA], [https://pdbe.org/1otm PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1otm RCSB], [https://www.ebi.ac.uk/pdbsum/1otm PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1otm ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[https://www.uniprot.org/uniprot/INLB_LISMO INLB_LISMO]] Mediates the entry of Listeria monocytogenes into cells.	+	[https://www.uniprot.org/uniprot/INLB_LISMO INLB_LISMO] Mediates the entry of Listeria monocytogenes into cells.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 32:		Line 32:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Bacterium monocytogenes hominis nyfeldt 1932]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Chapman, T]]	+	[[Category: Listeria monocytogenes]]
-	[[Category: Copp, J]]	+	[[Category: Chapman T]]
-	[[Category: Cossart, P]]	+	[[Category: Copp J]]
-	[[Category: Dramsi, S]]	+	[[Category: Cossart P]]
-	~~[[Category: Geer, P van der~~]]	+	[[Category: Dramsi S]]
-	[[Category: Ghosh, P]]	+	[[Category: Ghosh P]]
-	[[Category: Marino, M]]	+	[[Category: Marino M]]
-	[[Category: ~~Calcium-binding]]~~	+	[[Category: Van der Geer P]]
-	~~[[Category: Cell adhesion]]~~	+
-	~~[[Category: Inlb]]~~	+
-	~~[[Category: Internalin]]~~	+
-	~~[[Category: Invasion]]~~	+
-	~~[[Category: Listeria~~]]	+

OCA at 08:58, 21 April 2021

OCA — Wed, 21 Apr 2021 08:58:11 GMT

←Older revision		Revision as of 08:58, 21 April 2021
Line 3:		Line 3:
	<StructureSection load='1otm' size='340' side='right'caption='[[1otm]], [[Resolution\|resolution]] 1.93Å' scene=''>		<StructureSection load='1otm' size='340' side='right'caption='[[1otm]], [[Resolution\|resolution]] 1.93Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1otm]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/"bacterium_monocytogenes_hominis"_nyfeldt_1932 "bacterium monocytogenes hominis" nyfeldt 1932]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1OTM OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1OTM FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1otm]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/"bacterium_monocytogenes_hominis"_nyfeldt_1932 "bacterium monocytogenes hominis" nyfeldt 1932]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1OTM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1OTM FirstGlance]. <br>
-	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1d0b\|1d0b]]</td></tr>	+	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1d0b\|1d0b]]</div></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1otm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1otm OCA], [~~http~~://pdbe.org/1otm PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=1otm RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/1otm PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=1otm ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1otm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1otm OCA], [https://pdbe.org/1otm PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1otm RCSB], [https://www.ebi.ac.uk/pdbsum/1otm PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1otm ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[~~http~~://www.uniprot.org/uniprot/INLB_LISMO INLB_LISMO]] Mediates the entry of Listeria monocytogenes into cells.	+	[[https://www.uniprot.org/uniprot/INLB_LISMO INLB_LISMO]] Mediates the entry of Listeria monocytogenes into cells.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]

OCA at 13:31, 17 July 2019

OCA — Wed, 17 Jul 2019 13:31:11 GMT

←Older revision		Revision as of 13:31, 17 July 2019
Line 1:		Line 1:

	==Calcium-binding mutant of the internalin B LRR domain==		==Calcium-binding mutant of the internalin B LRR domain==
-	<StructureSection load='1otm' size='340' side='right' caption='[[1otm]], [[Resolution\|resolution]] 1.93Å' scene=''>	+	<StructureSection load='1otm' size='340' side='right'caption='[[1otm]], [[Resolution\|resolution]] 1.93Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1otm]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacterium_monocytogenes_hominis"_nyfeldt_1932 "bacterium monocytogenes hominis" nyfeldt 1932]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1OTM OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1OTM FirstGlance]. <br>		<table><tr><td colspan='2'>[[1otm]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacterium_monocytogenes_hominis"_nyfeldt_1932 "bacterium monocytogenes hominis" nyfeldt 1932]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1OTM OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1OTM FirstGlance]. <br>
Line 13:		Line 13:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ot/1otm_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ot/1otm_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
Line 33:		Line 33:
	</StructureSection>		</StructureSection>
	[[Category: Bacterium monocytogenes hominis nyfeldt 1932]]		[[Category: Bacterium monocytogenes hominis nyfeldt 1932]]
		+	[[Category: Large Structures]]
	[[Category: Chapman, T]]		[[Category: Chapman, T]]
	[[Category: Copp, J]]		[[Category: Copp, J]]

OCA at 09:30, 12 October 2017

OCA — Thu, 12 Oct 2017 09:30:19 GMT

←Older revision		Revision as of 09:30, 12 October 2017
Line 1:		Line 1:
		+
	==Calcium-binding mutant of the internalin B LRR domain==		==Calcium-binding mutant of the internalin B LRR domain==
	<StructureSection load='1otm' size='340' side='right' caption='[[1otm]], [[Resolution\|resolution]] 1.93Å' scene=''>		<StructureSection load='1otm' size='340' side='right' caption='[[1otm]], [[Resolution\|resolution]] 1.93Å' scene=''>
Line 4:		Line 5:
	<table><tr><td colspan='2'>[[1otm]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacterium_monocytogenes_hominis"_nyfeldt_1932 "bacterium monocytogenes hominis" nyfeldt 1932]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1OTM OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1OTM FirstGlance]. <br>		<table><tr><td colspan='2'>[[1otm]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacterium_monocytogenes_hominis"_nyfeldt_1932 "bacterium monocytogenes hominis" nyfeldt 1932]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1OTM OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1OTM FirstGlance]. <br>
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1d0b\|1d0b]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1d0b\|1d0b]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1otm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1otm OCA], [http://pdbe.org/1otm PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1otm RCSB], [http://www.ebi.ac.uk/pdbsum/1otm PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1otm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1otm OCA], [http://pdbe.org/1otm PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1otm RCSB], [http://www.ebi.ac.uk/pdbsum/1otm PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1otm ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==

OCA at 13:49, 9 February 2016

OCA — Tue, 09 Feb 2016 13:49:07 GMT

←Older revision		Revision as of 13:49, 9 February 2016
Line 16:		Line 16:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1otm ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 22:50, 10 September 2015

OCA — Thu, 10 Sep 2015 22:50:19 GMT

←Older revision		Revision as of 22:50, 10 September 2015
Line 2:		Line 2:
	<StructureSection load='1otm' size='340' side='right' caption='[[1otm]], [[Resolution\|resolution]] 1.93Å' scene=''>		<StructureSection load='1otm' size='340' side='right' caption='[[1otm]], [[Resolution\|resolution]] 1.93Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1otm]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Listeria_monocytogenes Listeria~~ monocytogenes]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1OTM OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1OTM FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1otm]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacterium_monocytogenes_hominis"_nyfeldt_1932 "bacterium monocytogenes hominis" nyfeldt 1932]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1OTM OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1OTM FirstGlance]. <br>
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1d0b\|1d0b]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1d0b\|1d0b]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1otm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1otm OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1otm RCSB], [http://www.ebi.ac.uk/pdbsum/1otm PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1otm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1otm OCA], [http://pdbe.org/1otm PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1otm RCSB], [http://www.ebi.ac.uk/pdbsum/1otm PDBsum]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 26:		Line 26:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 1otm" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Listeria~~ monocytogenes]]	+	[[Category: Bacterium monocytogenes hominis nyfeldt 1932]]
	[[Category: Chapman, T]]		[[Category: Chapman, T]]
	[[Category: Copp, J]]		[[Category: Copp, J]]

OCA at 07:11, 25 December 2014

OCA — Thu, 25 Dec 2014 07:11:24 GMT

←Older revision		Revision as of 07:11, 25 December 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1otm]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Listeria_monocytogenes Listeria monocytogenes]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1OTM OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1OTM FirstGlance]. <br>		<table><tr><td colspan='2'>[[1otm]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Listeria_monocytogenes Listeria monocytogenes]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1OTM OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1OTM FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1d0b\|1d0b]]</td></tr>	+	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1d0b\|1d0b]]</td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1otm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1otm OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1otm RCSB], [http://www.ebi.ac.uk/pdbsum/1otm PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1otm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1otm OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1otm RCSB], [http://www.ebi.ac.uk/pdbsum/1otm PDBsum]</span></td></tr>
-	<table>	+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/INLB_LISMO INLB_LISMO]] Mediates the entry of Listeria monocytogenes into cells.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 29:		Line 31:
	</StructureSection>		</StructureSection>
	[[Category: Listeria monocytogenes]]		[[Category: Listeria monocytogenes]]
-	[[Category: Chapman, T.]]	+	[[Category: Chapman, T]]
-	[[Category: Copp, J.]]	+	[[Category: Copp, J]]
-	[[Category: Cossart, P.]]	+	[[Category: Cossart, P]]
-	[[Category: Dramsi, S.]]	+	[[Category: Dramsi, S]]
-	[[Category: Geer, P van der.]]	+	[[Category: Geer, P van der]]
-	[[Category: Ghosh, P.]]	+	[[Category: Ghosh, P]]
-	[[Category: Marino, M.]]	+	[[Category: Marino, M]]
	[[Category: Calcium-binding]]		[[Category: Calcium-binding]]
	[[Category: Cell adhesion]]		[[Category: Cell adhesion]]

OCA at 19:46, 28 September 2014

OCA — Sun, 28 Sep 2014 19:46:58 GMT

←Older revision		Revision as of 19:46, 28 September 2014
Line 1:		Line 1:
-	[[~~Image:~~1otm.~~png~~\|~~left~~\|200px]]	+	==Calcium-binding mutant of the internalin B LRR domain==
		+	<StructureSection load='1otm' size='340' side='right' caption='[[1otm]], [[Resolution\|resolution]] 1.93Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[1otm]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Listeria_monocytogenes Listeria monocytogenes]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1OTM OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1OTM FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1d0b\|1d0b]]</td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1otm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1otm OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1otm RCSB], [http://www.ebi.ac.uk/pdbsum/1otm PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ot/1otm_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	The Listeria monocytogenes protein InlB promotes invasion of mammalian cells through activation of the receptor tyrosine kinase Met. The InlB N-cap, a approximately 40 residue part of the domain that binds Met, was previously observed to bind two calcium ions in a novel and unusually exposed manner. Because subsequent work raised questions about the existence of these calcium-binding sites, we assayed calcium binding in solution to the InlB N-cap. We show that calcium ions are bound with dissociation constants in the low micromolar range at the two identified sites, and that the sites interact with one another. We demonstrate that the calcium ions are not required for structure, and also find that they have no appreciable effect on Met activation or intracellular invasion. Therefore, our results indicate that the sites are fortuitous in InlB, but also suggest that the simple architecture of the sites may be adaptable for protein engineering purposes.

-	~~{{STRUCTURE_1otm\| PDB=1otm \| SCENE= }}~~	+	Characterization of the calcium-binding sites of Listeria monocytogenes InlB.,Marino M, Banerjee M, Copp J, Dramsi S, Chapman T, van der Geer P, Cossart P, Ghosh P Biochem Biophys Res Commun. 2004 Apr 2;316(2):379-86. PMID:15020228<ref>PMID:15020228</ref>

-	~~===Calcium-binding mutant~~ of the ~~internalin B LRR domain===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_15020228}}~~	+	== References ==
-		+	<references/>
-	~~==About this Structure==~~	+	__TOC__
-	~~[[1otm]] is a 1 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Listeria_monocytogenes Listeria monocytogenes]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=1OTM OCA].~~	+	</StructureSection>
-		+
-	==~~Reference~~==	+
-	<~~ref group="xtra">PMID:015020228<~~/~~ref~~><~~references group="xtra"~~/>	+
	[[Category: Listeria monocytogenes]]		[[Category: Listeria monocytogenes]]
	[[Category: Chapman, T.]]		[[Category: Chapman, T.]]

OCA: Protected "1otm" [edit=sysop:move=sysop]

OCA — Wed, 12 Dec 2012 21:52:21 GMT

Protected "1otm" [edit=sysop:move=sysop]

←Older revision

Revision as of 21:52, 12 December 2012

OCA at 21:52, 12 December 2012

OCA — Wed, 12 Dec 2012 21:52:20 GMT

←Older revision		Revision as of 21:52, 12 December 2012
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-	{{Seed}}
	[[Image:1otm.png\|left\|200px]]		[[Image:1otm.png\|left\|200px]]

-	<!--
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	{{STRUCTURE_1otm\| PDB=1otm \| SCENE= }}		{{STRUCTURE_1otm\| PDB=1otm \| SCENE= }}

	===Calcium-binding mutant of the internalin B LRR domain===		===Calcium-binding mutant of the internalin B LRR domain===

-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_15020228}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where 15020228 is the PubMed ID number.
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	{{ABSTRACT_PUBMED_15020228}}		{{ABSTRACT_PUBMED_15020228}}

	==About this Structure==		==About this Structure==
-	~~1OTM~~ is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Listeria_monocytogenes Listeria monocytogenes]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1OTM OCA].	+	[[1otm]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Listeria_monocytogenes Listeria monocytogenes]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1OTM OCA].

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~15020228~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:015020228</ref><references group="xtra"/>
	[[Category: Listeria monocytogenes]]		[[Category: Listeria monocytogenes]]
	[[Category: Chapman, T.]]		[[Category: Chapman, T.]]
Line 33:		Line 21:
	[[Category: Marino, M.]]		[[Category: Marino, M.]]
	[[Category: Calcium-binding]]		[[Category: Calcium-binding]]
		+	[[Category: Cell adhesion]]
	[[Category: Inlb]]		[[Category: Inlb]]
	[[Category: Internalin]]		[[Category: Internalin]]
	[[Category: Invasion]]		[[Category: Invasion]]
	[[Category: Listeria]]		[[Category: Listeria]]
-
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 10:15:05 2009''