1ovi - Revision history

OCA at 09:21, 8 September 2021

OCA — Wed, 08 Sep 2021 09:21:59 GMT

←Older revision		Revision as of 09:21, 8 September 2021
Line 4:		Line 4:
	<StructureSection load='1ovi' size='340' side='right'caption='[[1ovi]]' scene=''>		<StructureSection load='1ovi' size='340' side='right'caption='[[1ovi]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1OVI FirstGlance]. <br>	+	<table><tr><td colspan='2'>For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1OVI FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1ovi FirstGlance], [~~http~~://www.ebi.ac.uk/pdbsum/1ovi PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=1ovi ProSAT]</span></td></tr>	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ovi FirstGlance], [https://www.ebi.ac.uk/pdbsum/1ovi PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ovi ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 10:19, 27 November 2019

OCA — Wed, 27 Nov 2019 10:19:41 GMT

←Older revision		Revision as of 10:19, 27 November 2019
Line 2:		Line 2:

	==A THREE DIMENSIONAL MODEL FOR BOVINE INTERFERON-TAU==		==A THREE DIMENSIONAL MODEL FOR BOVINE INTERFERON-TAU==
-	<StructureSection load='1ovi' size='340' side='right' caption='[[1ovi]]' scene=''>	+	<StructureSection load='1ovi' size='340' side='right'caption='[[1ovi]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1OVI FirstGlance]. <br>		<table><tr><td colspan='2'>For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1OVI FirstGlance]. <br>
Line 21:		Line 21:
	</StructureSection>		</StructureSection>
	[[Category: Theoretical Model]]		[[Category: Theoretical Model]]
		+	[[Category: Large Structures]]
	[[Category: Mitsui, Y]]		[[Category: Mitsui, Y]]
	[[Category: Saitoh, S]]		[[Category: Saitoh, S]]
	[[Category: Senda, T]]		[[Category: Senda, T]]

OCA at 07:49, 15 February 2018

OCA — Thu, 15 Feb 2018 07:49:30 GMT

←Older revision		Revision as of 07:49, 15 February 2018
Line 5:		Line 5:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1OVI FirstGlance]. <br>		<table><tr><td colspan='2'>For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1OVI FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ovi FirstGlance], [http://www.ebi.ac.uk/pdbsum/1ovi PDBsum]</span></td></tr>	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ovi FirstGlance], [http://www.ebi.ac.uk/pdbsum/1ovi PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1ovi ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 09:37, 11 February 2016

OCA — Thu, 11 Feb 2016 09:37:29 GMT

←Older revision		Revision as of 09:37, 11 February 2016
Line 1:		Line 1:
		+	{{Theoretical_model}}
		+
	==A THREE DIMENSIONAL MODEL FOR BOVINE INTERFERON-TAU==		==A THREE DIMENSIONAL MODEL FOR BOVINE INTERFERON-TAU==
	<StructureSection load='1ovi' size='340' side='right' caption='[[1ovi]]' scene=''>		<StructureSection load='1ovi' size='340' side='right' caption='[[1ovi]]' scene=''>
Line 18:		Line 20:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Theoretical Model]]
	[[Category: Mitsui, Y]]		[[Category: Mitsui, Y]]
	[[Category: Saitoh, S]]		[[Category: Saitoh, S]]
	[[Category: Senda, T]]		[[Category: Senda, T]]

OCA at 16:15, 11 September 2015

OCA — Fri, 11 Sep 2015 16:15:08 GMT

←Older revision		Revision as of 16:15, 11 September 2015
Line 13:		Line 13:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 1ovi" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>

OCA at 08:15, 6 January 2015

OCA — Tue, 06 Jan 2015 08:15:25 GMT

←Older revision		Revision as of 08:15, 6 January 2015
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1OVI FirstGlance]. <br>		<table><tr><td colspan='2'>For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1OVI FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ovi FirstGlance], [http://www.ebi.ac.uk/pdbsum/1ovi PDBsum]</span></td></tr>	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ovi FirstGlance], [http://www.ebi.ac.uk/pdbsum/1ovi PDBsum]</span></td></tr>
-	<table>	+	</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==

OCA at 00:04, 29 September 2014

OCA — Mon, 29 Sep 2014 00:04:08 GMT

←Older revision		Revision as of 00:04, 29 September 2014
Line 1:		Line 1:
-	~~{{Theoretical_model}}~~	+	==A THREE DIMENSIONAL MODEL FOR BOVINE INTERFERON-TAU==
		+	<StructureSection load='1ovi' size='340' side='right' caption='[[1ovi]]' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1OVI FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ovi FirstGlance], [http://www.ebi.ac.uk/pdbsum/1ovi PDBsum]</span></td></tr>
		+	<table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	The interferon-tau (IFN-tau) are type I IFN whose expression is restricted to the embryonic trophectoderm of the developing placenta of ruminant ungulate species, where they act as hormones of pregnancy. Here computer modeling has been used to generate homology models of bovine and ovine IFN-tau based on the refined crystal structure of murine IFN-beta. The IFN-tau structure, like that of MuIFN-beta, is based on five long alpha helices (A-E), one short helix in the middle of the loop connecting helices C and D and a long loop between helices A and B. BoIFN-tau differs from MuIFN-beta in three important respects. First, as in all IFN-tau, there is a carboxyl tail of nine amino acids that cannot be accurately modeled but that would have a length of approximately 30 A when fully extended. Second, like the IFN-alpha subtype, all IFN-tau have a three-amino acid insertion in loop AB and a likely disulfide bridge between Cys29 and Cys139 that lead to marked conformational differences between them and MuIFN-beta in a region (Leu22 to Arg33 in IFN-tau) believed to interact with the receptor. Third, all IFN-tau, as well as the related IFN-omega, possess a Gly at position 126 (rather than the equivalent Arg on MuIFN-beta and IFN-alpha) that will impair an extensive hydrogen bonding interaction between helix D and loop AB. As a result, the polypeptide segment around this region (Phe36 to Gln40) of loop AB is likely to be considerably more flexible than in other type I IFN.

-	~~[[Image~~:~~1ovi~~.~~png\|left\|200px]]~~	+	A three-dimensional model of interferon-tau.,Senda T, Saitoh SI, Mitsui Y, Li J, Roberts RM J Interferon Cytokine Res. 1995 Dec;15(12):1053-60. PMID:8746786<ref>PMID:8746786</ref>

-	~~{{STRUCTURE_1ovi\| PDB=1ovi \| SCENE= }}~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	==~~=A THREE DIMENSIONAL MODEL FOR BOVINE INTERFERON-TAU===~~	+	== References ==
-		+	<references/>
-	~~{{ABSTRACT_PUBMED_8746786}}~~	+	__TOC__
-		+	</StructureSection>
-	~~==Reference~~==	+
-	<~~ref group="xtra">PMID:008746786<~~/~~ref~~><~~references group="xtra"~~/>	+
	[[Category: Mitsui, Y]]		[[Category: Mitsui, Y]]
	[[Category: Saitoh, S]]		[[Category: Saitoh, S]]
	[[Category: Senda, T]]		[[Category: Senda, T]]

OCA: Protected "1ovi" [edit=sysop:move=sysop]

OCA — Sun, 21 Oct 2012 09:52:47 GMT

Protected "1ovi" [edit=sysop:move=sysop]

←Older revision

Revision as of 09:52, 21 October 2012

OCA at 09:52, 21 October 2012

OCA — Sun, 21 Oct 2012 09:52:44 GMT

←Older revision		Revision as of 09:52, 21 October 2012
Line 1:		Line 1:
	{{Theoretical_model}}		{{Theoretical_model}}
-	~~{{Seed}}~~	+
	[[Image:1ovi.png\|left\|200px]]		[[Image:1ovi.png\|left\|200px]]

-	<!--
-	The line below this paragraph, containing "STRUCTURE_1ovi", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_1ovi\| PDB=1ovi \| SCENE= }}		{{STRUCTURE_1ovi\| PDB=1ovi \| SCENE= }}

	===A THREE DIMENSIONAL MODEL FOR BOVINE INTERFERON-TAU===		===A THREE DIMENSIONAL MODEL FOR BOVINE INTERFERON-TAU===

-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_8746786}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where 8746786 is the PubMed ID number.
-	-->
	{{ABSTRACT_PUBMED_8746786}}		{{ABSTRACT_PUBMED_8746786}}
-
-	==About this Structure==
-	Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1OVI OCA].

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~8746786~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:008746786</ref><references group="xtra"/>
	[[Category: Mitsui, Y]]		[[Category: Mitsui, Y]]
	[[Category: Saitoh, S]]		[[Category: Saitoh, S]]
	[[Category: Senda, T]]		[[Category: Senda, T]]
-
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Apr 8 09:09:27 2010''

OCA at 06:09, 8 April 2010

OCA — Thu, 08 Apr 2010 06:09:28 GMT

←Older revision		Revision as of 06:09, 8 April 2010
Line 1:		Line 1:
-	~~'''Theoretical Model'''~~	+	{{Theoretical_model}}
		+	{{Seed}}
		+	[[Image:1ovi.png\|left\|200px]]

-	The ~~entry 1OVI~~ is ~~a Theoretical Model titled 'A THREE DIMENSIONAL MODEL FOR BOVINE INTERFERON-TAU'~~.	+	<!--
		+	The line below this paragraph, containing "STRUCTURE_1ovi", creates the "Structure Box" on the page.
		+	You may change the PDB parameter (which sets the PDB file loaded into the applet)
		+	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
		+	or leave the SCENE parameter empty for the default display.
		+	-->
		+	{{STRUCTURE_1ovi\| PDB=1ovi \| SCENE= }}

-	~~[[Category:Theoretical Model]]~~	+	===A THREE DIMENSIONAL MODEL FOR BOVINE INTERFERON-TAU===


-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on ~~Wed Jul 30~~ 09:52:~~28 2008~~''	+	<!--
		+	The line below this paragraph, {{ABSTRACT_PUBMED_8746786}}, adds the Publication Abstract to the page
		+	(as it appears on PubMed at http://www.pubmed.gov), where 8746786 is the PubMed ID number.
		+	-->
		+	{{ABSTRACT_PUBMED_8746786}}
		+
		+	==About this Structure==
		+	Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1OVI OCA].
		+
		+	==Reference==
		+	<ref group="xtra">PMID:8746786</ref><references group="xtra"/>
		+	[[Category: Mitsui, Y]]
		+	[[Category: Saitoh, S]]
		+	[[Category: Senda, T]]
		+
		+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Apr 8 09:09:27 2010''