1p0u - Revision history

OCA at 18:54, 29 November 2023

OCA — Wed, 29 Nov 2023 18:54:48 GMT

←Older revision		Revision as of 18:54, 29 November 2023
Line 1:		Line 1:

	==Sheared G/C Base Pair==		==Sheared G/C Base Pair==
-	<StructureSection load='1p0u' size='340' side='right'caption='[[1p0u~~]], [[NMR_Ensembles_of_Models \| 10 NMR models~~]]' scene=''>	+	<StructureSection load='1p0u' size='340' side='right'caption='[[1p0u]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1p0u]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1P0U OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1P0U FirstGlance]. <br>		<table><tr><td colspan='2'>[[1p0u]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1P0U OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1P0U FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1p0u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1p0u OCA], [https://pdbe.org/1p0u PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1p0u RCSB], [https://www.ebi.ac.uk/pdbsum/1p0u PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1p0u ProSAT]</span></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1p0u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1p0u OCA], [https://pdbe.org/1p0u PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1p0u RCSB], [https://www.ebi.ac.uk/pdbsum/1p0u PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1p0u ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 20:		Line 21:
	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Chin~~, K H~~]]	+	[[Category: Chin KH]]
-	[[Category: Chou~~, S H]]~~	+	[[Category: Chou SH]]
-	~~[[Category: Dna]]~~	+
-	~~[[Category: Sheared gc base pair]]~~	+
-	~~[[Category: Single-residue loop]]~~	+
-	~~[[Category: Syn cytidine~~]]	+

OCA at 09:23, 8 September 2021

OCA — Wed, 08 Sep 2021 09:23:33 GMT

←Older revision		Revision as of 09:23, 8 September 2021
Line 3:		Line 3:
	<StructureSection load='1p0u' size='340' side='right'caption='[[1p0u]], [[NMR_Ensembles_of_Models \| 10 NMR models]]' scene=''>		<StructureSection load='1p0u' size='340' side='right'caption='[[1p0u]], [[NMR_Ensembles_of_Models \| 10 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1p0u]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1P0U OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1P0U FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1p0u]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1P0U OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1P0U FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1p0u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1p0u OCA], [~~http~~://pdbe.org/1p0u PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=1p0u RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/1p0u PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=1p0u ProSAT]</span></td></tr>	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1p0u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1p0u OCA], [https://pdbe.org/1p0u PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1p0u RCSB], [https://www.ebi.ac.uk/pdbsum/1p0u PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1p0u ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 09:50, 27 November 2019

OCA — Wed, 27 Nov 2019 09:50:41 GMT

←Older revision		Revision as of 09:50, 27 November 2019
Line 1:		Line 1:

	==Sheared G/C Base Pair==		==Sheared G/C Base Pair==
-	<StructureSection load='1p0u' size='340' side='right' caption='[[1p0u]], [[NMR_Ensembles_of_Models \| 10 NMR models]]' scene=''>	+	<StructureSection load='1p0u' size='340' side='right'caption='[[1p0u]], [[NMR_Ensembles_of_Models \| 10 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1p0u]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1P0U OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1P0U FirstGlance]. <br>		<table><tr><td colspan='2'>[[1p0u]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1P0U OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1P0U FirstGlance]. <br>
Line 19:		Line 19:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Large Structures]]
	[[Category: Chin, K H]]		[[Category: Chin, K H]]
	[[Category: Chou, S H]]		[[Category: Chou, S H]]

OCA at 07:28, 15 February 2018

OCA — Thu, 15 Feb 2018 07:28:33 GMT

←Older revision		Revision as of 07:28, 15 February 2018
Line 1:		Line 1:
		+
	==Sheared G/C Base Pair==		==Sheared G/C Base Pair==
	<StructureSection load='1p0u' size='340' side='right' caption='[[1p0u]], [[NMR_Ensembles_of_Models \| 10 NMR models]]' scene=''>		<StructureSection load='1p0u' size='340' side='right' caption='[[1p0u]], [[NMR_Ensembles_of_Models \| 10 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1p0u]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1P0U OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1P0U FirstGlance]. <br>		<table><tr><td colspan='2'>[[1p0u]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1P0U OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1P0U FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1p0u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1p0u OCA], [http://pdbe.org/1p0u PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1p0u RCSB], [http://www.ebi.ac.uk/pdbsum/1p0u PDBsum]</span></td></tr>	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1p0u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1p0u OCA], [http://pdbe.org/1p0u PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1p0u RCSB], [http://www.ebi.ac.uk/pdbsum/1p0u PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1p0u ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 15:30, 10 September 2015

OCA — Thu, 10 Sep 2015 15:30:35 GMT

←Older revision		Revision as of 15:30, 10 September 2015
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1p0u]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1P0U OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1P0U FirstGlance]. <br>		<table><tr><td colspan='2'>[[1p0u]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1P0U OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1P0U FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1p0u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1p0u OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1p0u RCSB], [http://www.ebi.ac.uk/pdbsum/1p0u PDBsum]</span></td></tr>	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1p0u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1p0u OCA], [http://pdbe.org/1p0u PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1p0u RCSB], [http://www.ebi.ac.uk/pdbsum/1p0u PDBsum]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 13:		Line 13:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 1p0u" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>

OCA at 07:45, 6 January 2015

OCA — Tue, 06 Jan 2015 07:45:39 GMT

←Older revision		Revision as of 07:45, 6 January 2015
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1p0u]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1P0U OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1P0U FirstGlance]. <br>		<table><tr><td colspan='2'>[[1p0u]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1P0U OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1P0U FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1p0u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1p0u OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1p0u RCSB], [http://www.ebi.ac.uk/pdbsum/1p0u PDBsum]</span></td></tr>	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1p0u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1p0u OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1p0u RCSB], [http://www.ebi.ac.uk/pdbsum/1p0u PDBsum]</span></td></tr>
-	<table>	+	</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 17:		Line 17:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Chin, K H.]]	+	[[Category: Chin, K H]]
-	[[Category: Chou, S H.]]	+	[[Category: Chou, S H]]
	[[Category: Dna]]		[[Category: Dna]]
	[[Category: Sheared gc base pair]]		[[Category: Sheared gc base pair]]
	[[Category: Single-residue loop]]		[[Category: Single-residue loop]]
	[[Category: Syn cytidine]]		[[Category: Syn cytidine]]

OCA at 23:46, 28 September 2014

OCA — Sun, 28 Sep 2014 23:46:19 GMT

←Older revision		Revision as of 23:46, 28 September 2014
Line 1:		Line 1:
-	[[~~Image~~:1p0u.~~png\|left\|200px~~]]	+	==Sheared G/C Base Pair==
		+	<StructureSection load='1p0u' size='340' side='right' caption='[[1p0u]], [[NMR_Ensembles_of_Models \| 10 NMR models]]' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[1p0u]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1P0U OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1P0U FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1p0u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1p0u OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1p0u RCSB], [http://www.ebi.ac.uk/pdbsum/1p0u PDBsum]</span></td></tr>
		+	<table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Stable DNA loop structures closed by a novel G.C base-pair have been determined for the single-residue d(GXC) loops (X=A, T, G or C) in low-salt solution by high-resolution nuclear magnetic resonance (NMR) techniques. The closing G.C base-pair in these loops is not of the canonical Watson-Crick type, but adopts instead a unique sheared-type (trans Watson-Crick/sugar-edge) pairing, like those occurring in the sheared mismatched G.A or A.C base-pair, to draw the two opposite strands together. The cytidine residue in the closing base-pair is transformed into the rare syn domain to form two H-bonds with the guanine base and to prevent the steric clash between the G 2NH(2) and the C H-5 protons. Besides, the sugar pucker of the syn cytidine is still located in the regular C2'-endo domain, unlike the C3'-endo domain adopted for the pyrimidines of the out-of-alternation left-handed Z-DNA structure. The facile formation of the compact d(GXC) loops closed by a unique sheared-type G(anti).C(syn) base-pair demonstrates the great potential of the single-stranded d(GXC) triplet repeats to fold into stable hairpins.

-	~~{{STRUCTURE_1p0u\| PDB=1p0u \| SCENE= }}~~	+	Sheared-type G(anti).C(syn) base-pair: a unique d(GXC) loop closure motif.,Chin KH, Chou SH J Mol Biol. 2003 May 30;329(2):351-61. PMID:12758081<ref>PMID:12758081</ref>

-	~~===Sheared G~~/~~C Base Pair===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_12758081}}~~	+	== References ==
-		+	<references/>
-	==~~About this Structure~~==	+	__TOC__
-	~~[[1p0u]] is a 1 chain structure. Full experimental information is available from [http:~~//~~oca.weizmann.ac.il/oca-bin/ocashort?id=1P0U OCA].~~	+	</StructureSection>
	[[Category: Chin, K H.]]		[[Category: Chin, K H.]]
	[[Category: Chou, S H.]]		[[Category: Chou, S H.]]

OCA: Protected "1p0u" [edit=sysop:move=sysop]

OCA — Wed, 12 Dec 2012 21:48:44 GMT

Protected "1p0u" [edit=sysop:move=sysop]

←Older revision

Revision as of 21:48, 12 December 2012

OCA at 21:48, 12 December 2012

OCA — Wed, 12 Dec 2012 21:48:40 GMT

←Older revision		Revision as of 21:48, 12 December 2012
Line 1:		Line 1:
-	{{Seed}}
	[[Image:1p0u.png\|left\|200px]]		[[Image:1p0u.png\|left\|200px]]

-	<!--
-	The line below this paragraph, containing "STRUCTURE_1p0u", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_1p0u\| PDB=1p0u \| SCENE= }}		{{STRUCTURE_1p0u\| PDB=1p0u \| SCENE= }}

	===Sheared G/C Base Pair===		===Sheared G/C Base Pair===

-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_12758081}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where 12758081 is the PubMed ID number.
-	-->
	{{ABSTRACT_PUBMED_12758081}}		{{ABSTRACT_PUBMED_12758081}}

	==About this Structure==		==About this Structure==
-	Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1P0U OCA].	+	[[1p0u]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1P0U OCA].
-		+
-	~~==Reference==~~	+
-	~~Sheared-type G(anti).C(syn) base-pair: a unique d(GXC) loop closure motif., Chin KH, Chou SH, J Mol Biol. 2003 May 30;329(2):351-61. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12758081 12758081]~~	+
	[[Category: Chin, K H.]]		[[Category: Chin, K H.]]
	[[Category: Chou, S H.]]		[[Category: Chou, S H.]]
-	[[Category: ~~Nmr~~]]	+	[[Category: Dna]]
	[[Category: Sheared gc base pair]]		[[Category: Sheared gc base pair]]
	[[Category: Single-residue loop]]		[[Category: Single-residue loop]]
	[[Category: Syn cytidine]]		[[Category: Syn cytidine]]
-
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 06:56:55 2008''

OCA at 03:57, 28 July 2008

OCA — Mon, 28 Jul 2008 03:57:02 GMT

←Older revision		Revision as of 03:57, 28 July 2008
Line 1:		Line 1:
-	[[Image:1p0u.~~gif~~\|left\|200px]]	+	{{Seed}}
		+	[[Image:1p0u.png\|left\|200px]]

	<!--		<!--
Line 9:		Line 10:
	{{STRUCTURE_1p0u\| PDB=1p0u \| SCENE= }}		{{STRUCTURE_1p0u\| PDB=1p0u \| SCENE= }}

-	~~'''~~Sheared G/C Base Pair~~'''~~	+	===Sheared G/C Base Pair===


-	~~==Overview==~~	+	<!--
-	~~Stable DNA loop structures closed by a novel G.C base~~-~~pair have been determined for the single~~-~~residue d(GXC) loops (X=A~~, T, ~~G or C) in low-salt solution by high-resolution nuclear magnetic resonance (NMR) techniques. The closing G.C base-pair in these loops is not of~~ the ~~canonical Watson-Crick type, but adopts instead a unique sheared-type~~ (~~trans Watson-Crick~~/~~sugar-edge) pairing, like those occurring in the sheared mismatched G~~.~~A or A~~.C base-pair, to draw the two opposite strands together. The cytidine residue in the closing base-pair is transformed into the rare syn domain to form two H-bonds with the guanine base and to prevent the steric clash between the G 2NH(2) ~~and the C H-5 protons. Besides~~, ~~the sugar pucker of the syn cytidine~~ is ~~still located in~~ the ~~regular C2'-endo domain, unlike the C3'-endo domain adopted for the pyrimidines of the out-of-alternation left-handed Z-DNA structure~~. ~~The facile formation of the compact d(GXC) loops closed by a unique sheared~~-~~type G(anti).C(syn) base~~-~~pair demonstrates the great potential of the single-stranded d(GXC) triplet repeats to fold into stable hairpins.~~	+	The line below this paragraph, {{ABSTRACT_PUBMED_12758081}}, adds the Publication Abstract to the page
		+	(as it appears on PubMed at http://www.pubmed.gov), where 12758081 is the PubMed ID number.
		+	-->
		+	{{ABSTRACT_PUBMED_12758081}}

	==About this Structure==		==About this Structure==
-	Full ~~crystallographic~~ information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1P0U OCA].	+	Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1P0U OCA].

	==Reference==		==Reference==
Line 26:		Line 30:
	[[Category: Single-residue loop]]		[[Category: Single-residue loop]]
	[[Category: Syn cytidine]]		[[Category: Syn cytidine]]
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on ~~Sat May 3 04~~:32:25 2008''	+
		+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 06:56:55 2008''