1p3e - Revision history

OCA at 09:36, 16 August 2023

OCA — Wed, 16 Aug 2023 09:36:28 GMT

←Older revision		Revision as of 09:36, 16 August 2023
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	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1p3e]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_intermedius Bacillus intermedius]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1P3E OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1P3E FirstGlance]. <br>		<table><tr><td colspan='2'>[[1p3e]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_intermedius Bacillus intermedius]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1P3E OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1P3E FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=MPD:(4S)~~-~~2-METHYL-2~~,~~4-PENTANEDIOL'>MPD</scene>~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.72Å</td></tr>
-	<tr id='~~related~~'><td class="sblockLbl"><b>[[~~Related_structure~~\|~~Related~~:]]</b></td><td class="sblockDat"><~~div style~~='~~overflow~~: ~~auto; max~~-~~height: 3em;~~'>~~[[1p3c\|1p3c]]~~</~~div~~></td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1p3e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1p3e OCA], [https://pdbe.org/1p3e PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1p3e RCSB], [https://www.ebi.ac.uk/pdbsum/1p3e PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1p3e ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1p3e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1p3e OCA], [https://pdbe.org/1p3e PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1p3e RCSB], [https://www.ebi.ac.uk/pdbsum/1p3e PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1p3e ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/Q9EXR9_BACIN Q9EXR9_BACIN]
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
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	[[Category: Bacillus intermedius]]		[[Category: Bacillus intermedius]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Akimkina~~, T V~~]]	+	[[Category: Akimkina TV]]
-	[[Category: Blagova~~, E V~~]]	+	[[Category: Blagova EV]]
-	[[Category: Chestukhina~~, G G~~]]	+	[[Category: Chestukhina GG]]
-	[[Category: Kostrov~~, S V~~]]	+	[[Category: Kostrov SV]]
-	[[Category: Kuranova~~, I P~~]]	+	[[Category: Kuranova IP]]
-	[[Category: Lamzin~~, V S~~]]	+	[[Category: Lamzin VS]]
-	[[Category: Levdikov~~, V M~~]]	+	[[Category: Levdikov VM]]
-	[[Category: Meijers, R]]	+	[[Category: Meijers R]]
-	[[Category: Rudenskaya~~, G N]]~~	+	[[Category: Rudenskaya GN]]
-	~~[[Category: Glu specific]]~~	+
-	~~[[Category: Hydrolase]]~~	+
-	~~[[Category: Serine protease~~]]	+

OCA at 09:24, 8 September 2021

OCA — Wed, 08 Sep 2021 09:24:41 GMT

←Older revision		Revision as of 09:24, 8 September 2021
Line 3:		Line 3:
	<StructureSection load='1p3e' size='340' side='right'caption='[[1p3e]], [[Resolution\|resolution]] 1.72Å' scene=''>		<StructureSection load='1p3e' size='340' side='right'caption='[[1p3e]], [[Resolution\|resolution]] 1.72Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1p3e]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Bacillus_intermedius Bacillus intermedius]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1P3E OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1P3E FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1p3e]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_intermedius Bacillus intermedius]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1P3E OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1P3E FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1p3c\|1p3c]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1p3c\|1p3c]]</div></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1p3e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1p3e OCA], [~~http~~://pdbe.org/1p3e PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=1p3e RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/1p3e PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=1p3e ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1p3e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1p3e OCA], [https://pdbe.org/1p3e PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1p3e RCSB], [https://www.ebi.ac.uk/pdbsum/1p3e PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1p3e ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==

OCA at 10:13, 27 November 2019

OCA — Wed, 27 Nov 2019 10:13:48 GMT

←Older revision		Revision as of 10:13, 27 November 2019
Line 1:		Line 1:

	==Structure of Glu endopeptidase in complex with MPD==		==Structure of Glu endopeptidase in complex with MPD==
-	<StructureSection load='1p3e' size='340' side='right' caption='[[1p3e]], [[Resolution\|resolution]] 1.72Å' scene=''>	+	<StructureSection load='1p3e' size='340' side='right'caption='[[1p3e]], [[Resolution\|resolution]] 1.72Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1p3e]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacillus_intermedius Bacillus intermedius]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1P3E OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1P3E FirstGlance]. <br>		<table><tr><td colspan='2'>[[1p3e]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacillus_intermedius Bacillus intermedius]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1P3E OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1P3E FirstGlance]. <br>
Line 32:		Line 32:
	</StructureSection>		</StructureSection>
	[[Category: Bacillus intermedius]]		[[Category: Bacillus intermedius]]
		+	[[Category: Large Structures]]
	[[Category: Akimkina, T V]]		[[Category: Akimkina, T V]]
	[[Category: Blagova, E V]]		[[Category: Blagova, E V]]

OCA at 07:44, 15 February 2018

OCA — Thu, 15 Feb 2018 07:44:28 GMT

←Older revision		Revision as of 07:44, 15 February 2018
Line 1:		Line 1:
		+
	==Structure of Glu endopeptidase in complex with MPD==		==Structure of Glu endopeptidase in complex with MPD==
	<StructureSection load='1p3e' size='340' side='right' caption='[[1p3e]], [[Resolution\|resolution]] 1.72Å' scene=''>		<StructureSection load='1p3e' size='340' side='right' caption='[[1p3e]], [[Resolution\|resolution]] 1.72Å' scene=''>
Line 5:		Line 6:
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1p3c\|1p3c]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1p3c\|1p3c]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1p3e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1p3e OCA], [http://pdbe.org/1p3e PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1p3e RCSB], [http://www.ebi.ac.uk/pdbsum/1p3e PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1p3e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1p3e OCA], [http://pdbe.org/1p3e PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1p3e RCSB], [http://www.ebi.ac.uk/pdbsum/1p3e PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1p3e ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 11:		Line 12:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/p3/1p3e_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/p3/1p3e_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>

OCA at 01:41, 10 February 2016

OCA — Wed, 10 Feb 2016 01:41:21 GMT

←Older revision		Revision as of 01:41, 10 February 2016
Line 15:		Line 15:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1p3e ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 04:06, 11 September 2015

OCA — Fri, 11 Sep 2015 04:06:53 GMT

←Older revision		Revision as of 04:06, 11 September 2015
Line 5:		Line 5:
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1p3c\|1p3c]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1p3c\|1p3c]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1p3e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1p3e OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1p3e RCSB], [http://www.ebi.ac.uk/pdbsum/1p3e PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1p3e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1p3e OCA], [http://pdbe.org/1p3e PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1p3e RCSB], [http://www.ebi.ac.uk/pdbsum/1p3e PDBsum]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 25:		Line 25:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 1p3e" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>

OCA at 08:08, 6 January 2015

OCA — Tue, 06 Jan 2015 08:08:48 GMT

←Older revision		Revision as of 08:08, 6 January 2015
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1p3e]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacillus_intermedius Bacillus intermedius]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1P3E OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1P3E FirstGlance]. <br>		<table><tr><td colspan='2'>[[1p3e]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacillus_intermedius Bacillus intermedius]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1P3E OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1P3E FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene><br>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene></td></tr>
-	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1p3c\|1p3c]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1p3c\|1p3c]]</td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1p3e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1p3e OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1p3e RCSB], [http://www.ebi.ac.uk/pdbsum/1p3e PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1p3e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1p3e OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1p3e RCSB], [http://www.ebi.ac.uk/pdbsum/1p3e PDBsum]</span></td></tr>
-	<table>	+	</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 30:		Line 30:
	</StructureSection>		</StructureSection>
	[[Category: Bacillus intermedius]]		[[Category: Bacillus intermedius]]
-	[[Category: Akimkina, T V.]]	+	[[Category: Akimkina, T V]]
-	[[Category: Blagova, E V.]]	+	[[Category: Blagova, E V]]
-	[[Category: Chestukhina, G G.]]	+	[[Category: Chestukhina, G G]]
-	[[Category: Kostrov, S V.]]	+	[[Category: Kostrov, S V]]
-	[[Category: Kuranova, I P.]]	+	[[Category: Kuranova, I P]]
-	[[Category: Lamzin, V S.]]	+	[[Category: Lamzin, V S]]
-	[[Category: Levdikov, V M.]]	+	[[Category: Levdikov, V M]]
-	[[Category: Meijers, R.]]	+	[[Category: Meijers, R]]
-	[[Category: Rudenskaya, G N.]]	+	[[Category: Rudenskaya, G N]]
	[[Category: Glu specific]]		[[Category: Glu specific]]
	[[Category: Hydrolase]]		[[Category: Hydrolase]]
	[[Category: Serine protease]]		[[Category: Serine protease]]

OCA at 23:59, 28 September 2014

OCA — Sun, 28 Sep 2014 23:59:44 GMT

←Older revision		Revision as of 23:59, 28 September 2014
Line 1:		Line 1:
-	[[~~Image:~~1p3e.~~png~~\|~~left~~\|200px]]	+	==Structure of Glu endopeptidase in complex with MPD==
		+	<StructureSection load='1p3e' size='340' side='right' caption='[[1p3e]], [[Resolution\|resolution]] 1.72Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[1p3e]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacillus_intermedius Bacillus intermedius]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1P3E OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1P3E FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene><br>
		+	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1p3c\|1p3c]]</td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1p3e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1p3e OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1p3e RCSB], [http://www.ebi.ac.uk/pdbsum/1p3e PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/p3/1p3e_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Extracellular glutamyl endopeptidase from Bacillus intermedius (BIEP) is a chymotrypsin-like serine protease which cleaves the peptide bond on the carboxyl side of glutamic acid. Its three-dimensional structure was determined for C222(1) and C2 crystal forms of BIEP to 1.5 and 1.75 A resolution, respectively. The topology of BIEP diverges from the most common chymotrypsin architecture, because one of the domains consists of a beta-sandwich consisting of two antiparallel beta-sheets and two helices. In the C2 crystals, a 2-methyl-2,4-pentanediol (MPD) molecule was found in the substrate binding site, mimicking a glutamic acid. This enabled the identification of the residues involved in the substrate recognition. The presence of the MPD molecule causes a change in the active site; the interaction between two catalytic residues (His47 and Ser171) is disrupted. The N-terminal end of the enzyme is involved in the formation of the substrate binding pocket. This indicates a direct relation between zymogen activation and substrate charge compensation.

-	~~{{STRUCTURE_1p3e\| PDB=1p3e \| SCENE= }}~~	+	The crystal structure of glutamyl endopeptidase from Bacillus intermedius reveals a structural link between zymogen activation and charge compensation.,Meijers R, Blagova EV, Levdikov VM, Rudenskaya GN, Chestukhina GG, Akimkina TV, Kostrov SV, Lamzin VS, Kuranova IP Biochemistry. 2004 Mar 16;43(10):2784-91. PMID:15005613<ref>PMID:15005613</ref>

-	~~===Structure~~ of ~~Glu endopeptidase in complex with MPD===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_15005613}}~~	+	== References ==
-		+	<references/>
-	~~==About this Structure==~~	+	__TOC__
-	~~[[1p3e]] is a 1 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Bacillus_intermedius Bacillus intermedius]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=1P3E OCA].~~	+	</StructureSection>
-		+
-	==~~Reference~~==	+
-	<~~ref group="xtra">PMID:015005613<~~/~~ref~~><~~references group="xtra"~~/>	+
	[[Category: Bacillus intermedius]]		[[Category: Bacillus intermedius]]
	[[Category: Akimkina, T V.]]		[[Category: Akimkina, T V.]]

OCA: Protected "1p3e" [edit=sysop:move=sysop]

OCA — Wed, 19 Dec 2012 11:48:07 GMT

Protected "1p3e" [edit=sysop:move=sysop]

←Older revision

Revision as of 11:48, 19 December 2012

OCA at 11:48, 19 December 2012

OCA — Wed, 19 Dec 2012 11:48:04 GMT

←Older revision		Revision as of 11:48, 19 December 2012
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-	{{Seed}}
	[[Image:1p3e.png\|left\|200px]]		[[Image:1p3e.png\|left\|200px]]

-	<!--
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	{{STRUCTURE_1p3e\| PDB=1p3e \| SCENE= }}		{{STRUCTURE_1p3e\| PDB=1p3e \| SCENE= }}

	===Structure of Glu endopeptidase in complex with MPD===		===Structure of Glu endopeptidase in complex with MPD===

-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_15005613}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where 15005613 is the PubMed ID number.
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	{{ABSTRACT_PUBMED_15005613}}		{{ABSTRACT_PUBMED_15005613}}

	==About this Structure==		==About this Structure==
-	~~1P3E~~ is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Bacillus_intermedius Bacillus intermedius]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1P3E OCA].	+	[[1p3e]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacillus_intermedius Bacillus intermedius]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1P3E OCA].

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~15005613~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:015005613</ref><references group="xtra"/>
	[[Category: Bacillus intermedius]]		[[Category: Bacillus intermedius]]
	[[Category: Akimkina, T V.]]		[[Category: Akimkina, T V.]]
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	[[Category: Rudenskaya, G N.]]		[[Category: Rudenskaya, G N.]]
	[[Category: Glu specific]]		[[Category: Glu specific]]
		+	[[Category: Hydrolase]]
	[[Category: Serine protease]]		[[Category: Serine protease]]
-
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 14:23:39 2009''