1qhz - Revision history

OCA at 10:03, 16 August 2023

OCA — Wed, 16 Aug 2023 10:03:53 GMT

←Older revision		Revision as of 10:03, 16 August 2023
Line 3:		Line 3:
	<StructureSection load='1qhz' size='340' side='right'caption='[[1qhz]], [[Resolution\|resolution]] 1.95Å' scene=''>		<StructureSection load='1qhz' size='340' side='right'caption='[[1qhz]], [[Resolution\|resolution]] 1.95Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1qhz]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Atcc_700163 Atcc 700163~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QHZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1QHZ FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1qhz]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Salipaludibacillus_agaradhaerens Salipaludibacillus agaradhaerens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QHZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1QHZ FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.95Å</td></tr>
-	<tr id='~~related~~'><td class="sblockLbl"><b>[[~~Related_structure~~\|~~Related~~:]]</b></td><td class="sblockDat"~~><div style='overflow: auto; max-height: 3em;'>[[1qi0\|1qi0]], [[1qi2\|1qi2]]</div></td></tr>~~	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
-	~~<tr~~ id~~='activity'><td class~~="~~sblockLbl~~"><~~b>Activity:</b></td><td class~~=~~"sblockDat"><span class~~=~~'plainlinks~~'>~~[https://en.wikipedia.org/wiki/Cellulase Cellulase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.4 3.2.1.4]~~ </~~span~~></td></tr>	+
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1qhz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1qhz OCA], [https://pdbe.org/1qhz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1qhz RCSB], [https://www.ebi.ac.uk/pdbsum/1qhz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1qhz ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1qhz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1qhz OCA], [https://pdbe.org/1qhz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1qhz RCSB], [https://www.ebi.ac.uk/pdbsum/1qhz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1qhz ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/GUN5_SALAG GUN5_SALAG]
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Atcc 700163]]
-	[[Category: Cellulase]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: ~~Davies, G J~~]]	+	[[Category: Salipaludibacillus agaradhaerens]]
-	[[Category: ~~Schulein, M~~]]	+	[[Category: Davies GJ]]
-	[[Category: ~~Varrot, A~~]]	+	[[Category: Schulein M]]
-	[[Category: ~~Cellulose degradation]]~~	+	[[Category: Varrot A]]
-	~~[[Category: Endoglucanase]]~~	+
-	~~[[Category: Glycoshydrolase family 5]]~~	+
-	~~[[Category: Hydrolase~~]]	+

OCA at 09:57, 15 September 2021

OCA — Wed, 15 Sep 2021 09:57:26 GMT

←Older revision		Revision as of 09:57, 15 September 2021
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	<StructureSection load='1qhz' size='340' side='right'caption='[[1qhz]], [[Resolution\|resolution]] 1.95Å' scene=''>		<StructureSection load='1qhz' size='340' side='right'caption='[[1qhz]], [[Resolution\|resolution]] 1.95Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1qhz]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Atcc_700163 Atcc 700163]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QHZ OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1QHZ FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1qhz]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Atcc_700163 Atcc 700163]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QHZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1QHZ FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1qi0\|1qi0]], [[1qi2\|1qi2]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1qi0\|1qi0]], [[1qi2\|1qi2]]</div></td></tr>
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://en.wikipedia.org/wiki/Cellulase Cellulase], with EC number [~~http~~://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.4 3.2.1.4] </span></td></tr>	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Cellulase Cellulase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.4 3.2.1.4] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1qhz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1qhz OCA], [~~http~~://pdbe.org/1qhz PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=1qhz RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/1qhz PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=1qhz ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1qhz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1qhz OCA], [https://pdbe.org/1qhz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1qhz RCSB], [https://www.ebi.ac.uk/pdbsum/1qhz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1qhz ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==

OCA at 09:44, 27 November 2019

OCA — Wed, 27 Nov 2019 09:44:49 GMT

←Older revision		Revision as of 09:44, 27 November 2019
Line 1:		Line 1:

	==NATIVE TETRAGONAL STRUCTURE OF THE ENDOGLUCANASE CEL5A FROM BACILLUS AGARADHAERENS==		==NATIVE TETRAGONAL STRUCTURE OF THE ENDOGLUCANASE CEL5A FROM BACILLUS AGARADHAERENS==
-	<StructureSection load='1qhz' size='340' side='right' caption='[[1qhz]], [[Resolution\|resolution]] 1.95Å' scene=''>	+	<StructureSection load='1qhz' size='340' side='right'caption='[[1qhz]], [[Resolution\|resolution]] 1.95Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1qhz]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_700163 Atcc 700163]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QHZ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1QHZ FirstGlance]. <br>		<table><tr><td colspan='2'>[[1qhz]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_700163 Atcc 700163]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QHZ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1QHZ FirstGlance]. <br>
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	</div>		</div>
	<div class="pdbe-citations 1qhz" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 1qhz" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[Glucanase 3D structures\|Glucanase 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
Line 34:		Line 37:
	[[Category: Atcc 700163]]		[[Category: Atcc 700163]]
	[[Category: Cellulase]]		[[Category: Cellulase]]
		+	[[Category: Large Structures]]
	[[Category: Davies, G J]]		[[Category: Davies, G J]]
	[[Category: Schulein, M]]		[[Category: Schulein, M]]

OCA at 07:51, 24 February 2018

OCA — Sat, 24 Feb 2018 07:51:56 GMT

←Older revision		Revision as of 07:51, 24 February 2018
Line 1:		Line 1:
		+
	==NATIVE TETRAGONAL STRUCTURE OF THE ENDOGLUCANASE CEL5A FROM BACILLUS AGARADHAERENS==		==NATIVE TETRAGONAL STRUCTURE OF THE ENDOGLUCANASE CEL5A FROM BACILLUS AGARADHAERENS==
	<StructureSection load='1qhz' size='340' side='right' caption='[[1qhz]], [[Resolution\|resolution]] 1.95Å' scene=''>		<StructureSection load='1qhz' size='340' side='right' caption='[[1qhz]], [[Resolution\|resolution]] 1.95Å' scene=''>
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	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1qi0\|1qi0]], [[1qi2\|1qi2]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1qi0\|1qi0]], [[1qi2\|1qi2]]</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Cellulase Cellulase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.4 3.2.1.4] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Cellulase Cellulase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.4 3.2.1.4] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1qhz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1qhz OCA], [http://pdbe.org/1qhz PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1qhz RCSB], [http://www.ebi.ac.uk/pdbsum/1qhz PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1qhz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1qhz OCA], [http://pdbe.org/1qhz PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1qhz RCSB], [http://www.ebi.ac.uk/pdbsum/1qhz PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1qhz ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
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	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/qh/1qhz_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/qh/1qhz_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1qhz ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
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	</div>		</div>
	<div class="pdbe-citations 1qhz" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 1qhz" style="background-color:#fffaf0;"></div>
-
-	==See Also==
-	*[[Glucanase\|Glucanase]]
	== References ==		== References ==
	<references/>		<references/>

OCA at 01:14, 12 September 2015

OCA — Sat, 12 Sep 2015 01:14:45 GMT

←Older revision		Revision as of 01:14, 12 September 2015
Line 2:		Line 2:
	<StructureSection load='1qhz' size='340' side='right' caption='[[1qhz]], [[Resolution\|resolution]] 1.95Å' scene=''>		<StructureSection load='1qhz' size='340' side='right' caption='[[1qhz]], [[Resolution\|resolution]] 1.95Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1qhz]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Bacillus_agaradhaerens Bacillus agaradhaerens~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QHZ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1QHZ FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1qhz]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_700163 Atcc 700163]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QHZ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1QHZ FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1qi0\|1qi0]], [[1qi2\|1qi2]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1qi0\|1qi0]], [[1qi2\|1qi2]]</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Cellulase Cellulase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.4 3.2.1.4] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Cellulase Cellulase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.4 3.2.1.4] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1qhz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1qhz OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1qhz RCSB], [http://www.ebi.ac.uk/pdbsum/1qhz PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1qhz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1qhz OCA], [http://pdbe.org/1qhz PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1qhz RCSB], [http://www.ebi.ac.uk/pdbsum/1qhz PDBsum]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
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	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 1qhz" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
Line 33:		Line 34:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Bacillus agaradhaerens~~]]	+	[[Category: Atcc 700163]]
	[[Category: Cellulase]]		[[Category: Cellulase]]
	[[Category: Davies, G J]]		[[Category: Davies, G J]]

OCA at 06:35, 6 January 2015

OCA — Tue, 06 Jan 2015 06:35:32 GMT

←Older revision		Revision as of 06:35, 6 January 2015
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1qhz]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacillus_agaradhaerens Bacillus agaradhaerens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QHZ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1QHZ FirstGlance]. <br>		<table><tr><td colspan='2'>[[1qhz]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacillus_agaradhaerens Bacillus agaradhaerens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QHZ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1QHZ FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene><br>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
-	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1qi0\|1qi0]], [[1qi2\|1qi2]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1qi0\|1qi0]], [[1qi2\|1qi2]]</td></tr>
-	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Cellulase Cellulase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.4 3.2.1.4] </span></td></tr>	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Cellulase Cellulase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.4 3.2.1.4] </span></td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1qhz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1qhz OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1qhz RCSB], [http://www.ebi.ac.uk/pdbsum/1qhz PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1qhz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1qhz OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1qhz RCSB], [http://www.ebi.ac.uk/pdbsum/1qhz PDBsum]</span></td></tr>
-	<table>	+	</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
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	[[Category: Bacillus agaradhaerens]]		[[Category: Bacillus agaradhaerens]]
	[[Category: Cellulase]]		[[Category: Cellulase]]
-	[[Category: Davies, G J.]]	+	[[Category: Davies, G J]]
-	[[Category: Schulein, M.]]	+	[[Category: Schulein, M]]
-	[[Category: Varrot, A.]]	+	[[Category: Varrot, A]]
	[[Category: Cellulose degradation]]		[[Category: Cellulose degradation]]
	[[Category: Endoglucanase]]		[[Category: Endoglucanase]]
	[[Category: Glycoshydrolase family 5]]		[[Category: Glycoshydrolase family 5]]
	[[Category: Hydrolase]]		[[Category: Hydrolase]]

OCA at 23:10, 28 September 2014

OCA — Sun, 28 Sep 2014 23:10:30 GMT

←Older revision		Revision as of 23:10, 28 September 2014
Line 1:		Line 1:
-	[[~~Image:~~1qhz.~~png~~\|~~left~~\|200px]]	+	==NATIVE TETRAGONAL STRUCTURE OF THE ENDOGLUCANASE CEL5A FROM BACILLUS AGARADHAERENS==
		+	<StructureSection load='1qhz' size='340' side='right' caption='[[1qhz]], [[Resolution\|resolution]] 1.95Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[1qhz]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacillus_agaradhaerens Bacillus agaradhaerens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QHZ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1QHZ FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene><br>
		+	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1qi0\|1qi0]], [[1qi2\|1qi2]]</td></tr>
		+	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Cellulase Cellulase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.4 3.2.1.4] </span></td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1qhz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1qhz OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1qhz RCSB], [http://www.ebi.ac.uk/pdbsum/1qhz PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/qh/1qhz_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Glycoside hydrolases are ubiquitous enzymes involved in a diverse array of biological processes, from the breakdown of biomass, through to viral invasion and cellular signalling. Endoglucanase Cel5A from Bacillus agaradhaerens, classified into glycoside hydrolase family 5, has been studied in a catalytically inactive crystal form at low pH conditions, in which native and complex structures revealed the importance of ring distortion during catalysis. Here, we present the structure of Cel5A in a new crystal form obtained at higher pH values in which the enzyme is active "in-crystal". Native, cellotriosyl-enzyme intermediate and beta-d-cellobiose structures were solved at 1.95, 1.75 and 2.1 A resolution, respectively. These structures reveal two classes of conformational change: those caused by crystal-packing and pH, with others induced upon substrate binding. At pH 7 a histidine residue, His206, implicated in substrate-binding and catalysis, but previously far removed from the substrate-binding cleft, moves over 10 A into the active site cleft in order to interact with the substrate in the +2 subsite. Occupation of the -1 subsite by substrate induces a loop closure to optimise protein-ligand interactions. Cel5A, along with the unrelated family 45 and family 6 cellulases, provides further evidence of substantial conformational change in response to ligand binding for this class of hydrolytic enzyme.

-	~~{{STRUCTURE_1qhz\| PDB=1qhz \| SCENE= }}~~	+	Insights into ligand-induced conformational change in Cel5A from Bacillus agaradhaerens revealed by a catalytically active crystal form.,Varrot A, Schulein M, Davies GJ J Mol Biol. 2000 Mar 31;297(3):819-28. PMID:10731432<ref>PMID:10731432</ref>

-	~~===NATIVE TETRAGONAL STRUCTURE OF THE ENDOGLUCANASE CEL5A FROM BACILLUS AGARADHAERENS===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_10731432}}~~	+
-		+
-	~~==About this Structure==~~	+
-	~~[[1qhz]] is~~ a ~~1 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Bacillus_agaradhaerens Bacillus agaradhaerens]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=1QHZ OCA].~~	+

	==See Also==		==See Also==
	*[[Glucanase\|Glucanase]]		*[[Glucanase\|Glucanase]]
-		+	== References ==
-	==~~Reference~~==	+	<references/>
-	<~~ref group="xtra">PMID:010731432<~~/~~ref~~><~~references group="xtra"~~/>	+	__TOC__
		+	</StructureSection>
	[[Category: Bacillus agaradhaerens]]		[[Category: Bacillus agaradhaerens]]
	[[Category: Cellulase]]		[[Category: Cellulase]]

OCA at 22:05, 20 October 2012

OCA — Sat, 20 Oct 2012 22:05:01 GMT

←Older revision		Revision as of 22:05, 20 October 2012
Line 8:		Line 8:

	==About this Structure==		==About this Structure==
-	[[1qhz]] is a 1 chain structure ~~of [[Glucanase]]~~ with sequence from [http://en.wikipedia.org/wiki/Bacillus_agaradhaerens Bacillus agaradhaerens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QHZ OCA].	+	[[1qhz]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacillus_agaradhaerens Bacillus agaradhaerens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QHZ OCA].

	==See Also==		==See Also==

OCA: Protected "1qhz" [edit=sysop:move=sysop]

OCA — Fri, 27 Jul 2012 15:12:13 GMT

Protected "1qhz" [edit=sysop:move=sysop]

←Older revision

Revision as of 15:12, 27 July 2012

OCA at 15:12, 27 July 2012

OCA — Fri, 27 Jul 2012 15:12:12 GMT

←Older revision		Revision as of 15:12, 27 July 2012
Line 1:		Line 1:
-	{{Seed}}
	[[Image:1qhz.png\|left\|200px]]		[[Image:1qhz.png\|left\|200px]]

-	<!--
-	The line below this paragraph, containing "STRUCTURE_1qhz", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_1qhz\| PDB=1qhz \| SCENE= }}		{{STRUCTURE_1qhz\| PDB=1qhz \| SCENE= }}

	===NATIVE TETRAGONAL STRUCTURE OF THE ENDOGLUCANASE CEL5A FROM BACILLUS AGARADHAERENS===		===NATIVE TETRAGONAL STRUCTURE OF THE ENDOGLUCANASE CEL5A FROM BACILLUS AGARADHAERENS===

-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_10731432}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where 10731432 is the PubMed ID number.
-	-->
	{{ABSTRACT_PUBMED_10731432}}		{{ABSTRACT_PUBMED_10731432}}

	==About this Structure==		==About this Structure==
-	~~1QHZ~~ is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Bacillus_agaradhaerens Bacillus agaradhaerens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QHZ OCA].	+	[[1qhz]] is a 1 chain structure of [[Glucanase]] with sequence from [http://en.wikipedia.org/wiki/Bacillus_agaradhaerens Bacillus agaradhaerens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QHZ OCA].
		+
		+	==See Also==
		+	*[[Glucanase\|Glucanase]]

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~10731432~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:010731432</ref><references group="xtra"/>
	[[Category: Bacillus agaradhaerens]]		[[Category: Bacillus agaradhaerens]]
	[[Category: Cellulase]]		[[Category: Cellulase]]
Line 33:		Line 24:
	[[Category: Glycoshydrolase family 5]]		[[Category: Glycoshydrolase family 5]]
	[[Category: Hydrolase]]		[[Category: Hydrolase]]
-
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 18 08:59:35 2009''