1qid - Revision history

OCA at 10:04, 16 August 2023

OCA — Wed, 16 Aug 2023 10:04:04 GMT

←Older revision		Revision as of 10:04, 16 August 2023
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	<StructureSection load='1qid' size='340' side='right'caption='[[1qid]], [[Resolution\|resolution]] 2.05Å' scene=''>		<StructureSection load='1qid' size='340' side='right'caption='[[1qid]], [[Resolution\|resolution]] 2.05Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1qid]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Torpedo_californica Torpedo~~ californica]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QID OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1QID FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1qid]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Tetronarce_californica Tetronarce californica]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QID OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1QID FirstGlance]. <br>
-	</td></tr><tr id='~~related~~'><td class="sblockLbl"><b>[[~~Related_structure~~\|~~Related~~:]]</b></td><td class="sblockDat">~~<div style='overflow: auto; max~~-~~height: 3em;'>[[1qie\|1qie]]~~, [[~~1qif~~\|~~1qif~~]]~~, [[1qig\|1qig]], [[1qih\|1qih]], [[1qii\|1qii]], [[1qij\|1qij]], [[1qik\|1qik]], [[1qim\|1qim]]</div></td></tr>~~	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.05Å</td></tr>
-	~~<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en~~.~~wikipedia.org/wiki/Acetylcholinesterase Acetylcholinesterase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.1.7 3.1.1.7] </span>~~</td></tr>	+
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1qid FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1qid OCA], [https://pdbe.org/1qid PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1qid RCSB], [https://www.ebi.ac.uk/pdbsum/1qid PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1qid ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1qid FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1qid OCA], [https://pdbe.org/1qid PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1qid RCSB], [https://www.ebi.ac.uk/pdbsum/1qid PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1qid ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[https://www.uniprot.org/uniprot/~~ACES_TORCA ACES_TORCA]~~] Terminates signal transduction at the neuromuscular junction by rapid hydrolysis of the acetylcholine released into the synaptic cleft. May be involved in cell-cell interactions.	+	[https://www.uniprot.org/uniprot/ACES_TETCF ACES_TETCF] Terminates signal transduction at the neuromuscular junction by rapid hydrolysis of the acetylcholine released into the synaptic cleft. May be involved in cell-cell interactions.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Acetylcholinesterase]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: ~~Torpedo~~ californica]]	+	[[Category: Tetronarce californica]]
-	[[Category: Kryger, G]]	+	[[Category: Kryger G]]
-	[[Category: Ravelli~~, R B.G~~]]	+	[[Category: Ravelli RBG]]
-	[[Category: Weik, M]]	+	[[Category: Weik M]]
-	~~[[Category: Alpha/beta hydrolase]]~~	+
-	~~[[Category: Catalytic triad]]~~	+
-	~~[[Category: Disulfide bond]]~~	+
-	~~[[Category: Glycosylated protein]]~~	+
-	~~[[Category: Hydrolase]]~~	+
-	~~[[Category: Neurotransmitter cleavage]]~~	+
-	~~[[Category: Radiation damage]]~~	+
-	~~[[Category: Serine hydrolase]]~~	+
-	~~[[Category: Time series~~]]	+

OCA at 09:57, 15 September 2021

OCA — Wed, 15 Sep 2021 09:57:45 GMT

←Older revision		Revision as of 09:57, 15 September 2021
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	<StructureSection load='1qid' size='340' side='right'caption='[[1qid]], [[Resolution\|resolution]] 2.05Å' scene=''>		<StructureSection load='1qid' size='340' side='right'caption='[[1qid]], [[Resolution\|resolution]] 2.05Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1qid]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Torpedo_californica Torpedo californica]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QID OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1QID FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1qid]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Torpedo_californica Torpedo californica]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QID OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1QID FirstGlance]. <br>
-	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1qie\|1qie]], [[1qif\|1qif]], [[1qig\|1qig]], [[1qih\|1qih]], [[1qii\|1qii]], [[1qij\|1qij]], [[1qik\|1qik]], [[1qim\|1qim]]</td></tr>	+	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1qie\|1qie]], [[1qif\|1qif]], [[1qig\|1qig]], [[1qih\|1qih]], [[1qii\|1qii]], [[1qij\|1qij]], [[1qik\|1qik]], [[1qim\|1qim]]</div></td></tr>
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://en.wikipedia.org/wiki/Acetylcholinesterase Acetylcholinesterase], with EC number [~~http~~://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.1.7 3.1.1.7] </span></td></tr>	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Acetylcholinesterase Acetylcholinesterase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.1.7 3.1.1.7] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1qid FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1qid OCA], [~~http~~://pdbe.org/1qid PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=1qid RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/1qid PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=1qid ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1qid FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1qid OCA], [https://pdbe.org/1qid PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1qid RCSB], [https://www.ebi.ac.uk/pdbsum/1qid PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1qid ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[~~http~~://www.uniprot.org/uniprot/ACES_TORCA ACES_TORCA]] Terminates signal transduction at the neuromuscular junction by rapid hydrolysis of the acetylcholine released into the synaptic cleft. May be involved in cell-cell interactions.	+	[[https://www.uniprot.org/uniprot/ACES_TORCA ACES_TORCA]] Terminates signal transduction at the neuromuscular junction by rapid hydrolysis of the acetylcholine released into the synaptic cleft. May be involved in cell-cell interactions.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]

OCA at 09:45, 27 November 2019

OCA — Wed, 27 Nov 2019 09:45:43 GMT

←Older revision		Revision as of 09:45, 27 November 2019
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	==SPECIFIC CHEMICAL AND STRUCTURAL DAMAGE AT NINE TIME POINTS (POINT A) CAUSED BY INTENSE SYNCHROTRON RADIATION TO TORPEDO CALIFORNICA ACETYLCHOLINESTERASE==		==SPECIFIC CHEMICAL AND STRUCTURAL DAMAGE AT NINE TIME POINTS (POINT A) CAUSED BY INTENSE SYNCHROTRON RADIATION TO TORPEDO CALIFORNICA ACETYLCHOLINESTERASE==
-	<StructureSection load='1qid' size='340' side='right' caption='[[1qid]], [[Resolution\|resolution]] 2.05Å' scene=''>	+	<StructureSection load='1qid' size='340' side='right'caption='[[1qid]], [[Resolution\|resolution]] 2.05Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1qid]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Torpedo_californica Torpedo californica]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QID OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1QID FirstGlance]. <br>		<table><tr><td colspan='2'>[[1qid]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Torpedo_californica Torpedo californica]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QID OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1QID FirstGlance]. <br>
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	</div>		</div>
	<div class="pdbe-citations 1qid" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 1qid" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[Acetylcholinesterase 3D structures\|Acetylcholinesterase 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
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	</StructureSection>		</StructureSection>
	[[Category: Acetylcholinesterase]]		[[Category: Acetylcholinesterase]]
		+	[[Category: Large Structures]]
	[[Category: Torpedo californica]]		[[Category: Torpedo californica]]
	[[Category: Kryger, G]]		[[Category: Kryger, G]]

OCA at 07:52, 24 February 2018

OCA — Sat, 24 Feb 2018 07:52:42 GMT

←Older revision		Revision as of 07:52, 24 February 2018
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		+
	==SPECIFIC CHEMICAL AND STRUCTURAL DAMAGE AT NINE TIME POINTS (POINT A) CAUSED BY INTENSE SYNCHROTRON RADIATION TO TORPEDO CALIFORNICA ACETYLCHOLINESTERASE==		==SPECIFIC CHEMICAL AND STRUCTURAL DAMAGE AT NINE TIME POINTS (POINT A) CAUSED BY INTENSE SYNCHROTRON RADIATION TO TORPEDO CALIFORNICA ACETYLCHOLINESTERASE==
	<StructureSection load='1qid' size='340' side='right' caption='[[1qid]], [[Resolution\|resolution]] 2.05Å' scene=''>		<StructureSection load='1qid' size='340' side='right' caption='[[1qid]], [[Resolution\|resolution]] 2.05Å' scene=''>
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	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1qie\|1qie]], [[1qif\|1qif]], [[1qig\|1qig]], [[1qih\|1qih]], [[1qii\|1qii]], [[1qij\|1qij]], [[1qik\|1qik]], [[1qim\|1qim]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1qie\|1qie]], [[1qif\|1qif]], [[1qig\|1qig]], [[1qih\|1qih]], [[1qii\|1qii]], [[1qij\|1qij]], [[1qik\|1qik]], [[1qim\|1qim]]</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Acetylcholinesterase Acetylcholinesterase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.1.7 3.1.1.7] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Acetylcholinesterase Acetylcholinesterase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.1.7 3.1.1.7] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1qid FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1qid OCA], [http://pdbe.org/1qid PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1qid RCSB], [http://www.ebi.ac.uk/pdbsum/1qid PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1qid FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1qid OCA], [http://pdbe.org/1qid PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1qid RCSB], [http://www.ebi.ac.uk/pdbsum/1qid PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1qid ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
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	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/qi/1qid_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/qi/1qid_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1qid ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
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	</div>		</div>
	<div class="pdbe-citations 1qid" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 1qid" style="background-color:#fffaf0;"></div>
-
-	==See Also==
-	*[[Acetylcholinesterase\|Acetylcholinesterase]]
	== References ==		== References ==
	<references/>		<references/>

OCA at 21:33, 11 September 2015

OCA — Fri, 11 Sep 2015 21:33:58 GMT

←Older revision		Revision as of 21:33, 11 September 2015
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	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1qie\|1qie]], [[1qif\|1qif]], [[1qig\|1qig]], [[1qih\|1qih]], [[1qii\|1qii]], [[1qij\|1qij]], [[1qik\|1qik]], [[1qim\|1qim]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1qie\|1qie]], [[1qif\|1qif]], [[1qig\|1qig]], [[1qih\|1qih]], [[1qii\|1qii]], [[1qij\|1qij]], [[1qik\|1qik]], [[1qim\|1qim]]</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Acetylcholinesterase Acetylcholinesterase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.1.7 3.1.1.7] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Acetylcholinesterase Acetylcholinesterase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.1.7 3.1.1.7] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1qid FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1qid OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1qid RCSB], [http://www.ebi.ac.uk/pdbsum/1qid PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1qid FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1qid OCA], [http://pdbe.org/1qid PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1qid RCSB], [http://www.ebi.ac.uk/pdbsum/1qid PDBsum]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
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	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 1qid" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==

OCA at 19:59, 25 December 2014

OCA — Thu, 25 Dec 2014 19:59:33 GMT

←Older revision		Revision as of 19:59, 25 December 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1qid]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Torpedo_californica Torpedo californica]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QID OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1QID FirstGlance]. <br>		<table><tr><td colspan='2'>[[1qid]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Torpedo_californica Torpedo californica]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QID OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1QID FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1qie\|1qie]], [[1qif\|1qif]], [[1qig\|1qig]], [[1qih\|1qih]], [[1qii\|1qii]], [[1qij\|1qij]], [[1qik\|1qik]], [[1qim\|1qim]]</td></tr>	+	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1qie\|1qie]], [[1qif\|1qif]], [[1qig\|1qig]], [[1qih\|1qih]], [[1qii\|1qii]], [[1qij\|1qij]], [[1qik\|1qik]], [[1qim\|1qim]]</td></tr>
-	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Acetylcholinesterase Acetylcholinesterase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.1.7 3.1.1.7] </span></td></tr>	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Acetylcholinesterase Acetylcholinesterase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.1.7 3.1.1.7] </span></td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1qid FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1qid OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1qid RCSB], [http://www.ebi.ac.uk/pdbsum/1qid PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1qid FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1qid OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1qid RCSB], [http://www.ebi.ac.uk/pdbsum/1qid PDBsum]</span></td></tr>
-	<table>	+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/ACES_TORCA ACES_TORCA]] Terminates signal transduction at the neuromuscular junction by rapid hydrolysis of the acetylcholine released into the synaptic cleft. May be involved in cell-cell interactions.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
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	[[Category: Acetylcholinesterase]]		[[Category: Acetylcholinesterase]]
	[[Category: Torpedo californica]]		[[Category: Torpedo californica]]
-	[[Category: Kryger, G.]]	+	[[Category: Kryger, G]]
-	[[Category: Ravelli, R B.G.]]	+	[[Category: Ravelli, R B.G]]
-	[[Category: Weik, M.]]	+	[[Category: Weik, M]]
	[[Category: Alpha/beta hydrolase]]		[[Category: Alpha/beta hydrolase]]
	[[Category: Catalytic triad]]		[[Category: Catalytic triad]]

OCA at 20:46, 28 September 2014

OCA — Sun, 28 Sep 2014 20:46:32 GMT

←Older revision		Revision as of 20:46, 28 September 2014
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-	[[~~Image:~~1qid.~~png~~\|~~left~~\|200px]]	+	==SPECIFIC CHEMICAL AND STRUCTURAL DAMAGE AT NINE TIME POINTS (POINT A) CAUSED BY INTENSE SYNCHROTRON RADIATION TO TORPEDO CALIFORNICA ACETYLCHOLINESTERASE==
		+	<StructureSection load='1qid' size='340' side='right' caption='[[1qid]], [[Resolution\|resolution]] 2.05Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[1qid]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Torpedo_californica Torpedo californica]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QID OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1QID FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1qie\|1qie]], [[1qif\|1qif]], [[1qig\|1qig]], [[1qih\|1qih]], [[1qii\|1qii]], [[1qij\|1qij]], [[1qik\|1qik]], [[1qim\|1qim]]</td></tr>
		+	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Acetylcholinesterase Acetylcholinesterase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.1.7 3.1.1.7] </span></td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1qid FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1qid OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1qid RCSB], [http://www.ebi.ac.uk/pdbsum/1qid PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/qi/1qid_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Radiation damage is an inherent problem in x-ray crystallography. It usually is presumed to be nonspecific and manifested as a gradual decay in the overall quality of data obtained for a given crystal as data collection proceeds. Based on third-generation synchrotron x-ray data, collected at cryogenic temperatures, we show for the enzymes Torpedo californica acetylcholinesterase and hen egg white lysozyme that synchrotron radiation also can cause highly specific damage. Disulfide bridges break, and carboxyl groups of acidic residues lose their definition. Highly exposed carboxyls, and those in the active site of both enzymes, appear particularly susceptible. The catalytic triad residue, His-440, in acetylcholinesterase, also appears to be much more sensitive to radiation damage than other histidine residues. Our findings have direct practical implications for routine x-ray data collection at high-energy synchrotron sources. Furthermore, they provide a direct approach for studying the radiation chemistry of proteins and nucleic acids at a detailed, structural level and also may yield information concerning putative "weak links" in a given biological macromolecule, which may be of structural and functional significance.

-	~~{{STRUCTURE_1qid\| PDB=1qid \| SCENE= }}~~	+	Specific chemical and structural damage to proteins produced by synchrotron radiation.,Weik M, Ravelli RB, Kryger G, McSweeney S, Raves ML, Harel M, Gros P, Silman I, Kroon J, Sussman JL Proc Natl Acad Sci U S A. 2000 Jan 18;97(2):623-8. PMID:10639129<ref>PMID:10639129</ref>

-	~~===SPECIFIC CHEMICAL AND STRUCTURAL DAMAGE AT NINE TIME POINTS (POINT A) CAUSED BY INTENSE SYNCHROTRON RADIATION TO TORPEDO CALIFORNICA ACETYLCHOLINESTERASE===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_10639129}}~~	+
-		+
-	~~==About this Structure==~~	+
-	~~[[1qid]] is~~ a ~~1 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Torpedo_californica Torpedo californica]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=1QID OCA].~~	+

	==See Also==		==See Also==
	*[[Acetylcholinesterase\|Acetylcholinesterase]]		*[[Acetylcholinesterase\|Acetylcholinesterase]]
-		+	== References ==
-	==~~Reference~~==	+	<references/>
-	<~~ref group="xtra">PMID:010639129<~~/~~ref~~><~~references group="xtra"~~/>	+	__TOC__
		+	</StructureSection>
	[[Category: Acetylcholinesterase]]		[[Category: Acetylcholinesterase]]
	[[Category: Torpedo californica]]		[[Category: Torpedo californica]]

OCA at 20:51, 20 October 2012

OCA — Sat, 20 Oct 2012 20:51:29 GMT

←Older revision		Revision as of 20:51, 20 October 2012
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	==About this Structure==		==About this Structure==
-	[[1qid]] is a 1 chain structure ~~of [[Acetylcholinesterase]]~~ with sequence from [http://en.wikipedia.org/wiki/Torpedo_californica Torpedo californica]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QID OCA].	+	[[1qid]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Torpedo_californica Torpedo californica]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QID OCA].

	==See Also==		==See Also==

OCA at 11:50, 27 July 2012

OCA — Fri, 27 Jul 2012 11:50:48 GMT

←Older revision		Revision as of 11:50, 27 July 2012
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	[[Image:1qid.png\|left\|200px]]		[[Image:1qid.png\|left\|200px]]

-	<!--
-	The line below this paragraph, containing "STRUCTURE_1qid", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_1qid\| PDB=1qid \| SCENE= }}		{{STRUCTURE_1qid\| PDB=1qid \| SCENE= }}

	===SPECIFIC CHEMICAL AND STRUCTURAL DAMAGE AT NINE TIME POINTS (POINT A) CAUSED BY INTENSE SYNCHROTRON RADIATION TO TORPEDO CALIFORNICA ACETYLCHOLINESTERASE===		===SPECIFIC CHEMICAL AND STRUCTURAL DAMAGE AT NINE TIME POINTS (POINT A) CAUSED BY INTENSE SYNCHROTRON RADIATION TO TORPEDO CALIFORNICA ACETYLCHOLINESTERASE===

-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_10639129}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where 10639129 is the PubMed ID number.
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	{{ABSTRACT_PUBMED_10639129}}		{{ABSTRACT_PUBMED_10639129}}

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	==See Also==		==See Also==
-	*[[Acetylcholinesterase]]	+	*[[Acetylcholinesterase\|Acetylcholinesterase]]

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~10639129~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:010639129</ref><references group="xtra"/>
	[[Category: Acetylcholinesterase]]		[[Category: Acetylcholinesterase]]
	[[Category: Torpedo californica]]		[[Category: Torpedo californica]]
Line 35:		Line 24:
	[[Category: Disulfide bond]]		[[Category: Disulfide bond]]
	[[Category: Glycosylated protein]]		[[Category: Glycosylated protein]]
		+	[[Category: Hydrolase]]
	[[Category: Neurotransmitter cleavage]]		[[Category: Neurotransmitter cleavage]]
	[[Category: Radiation damage]]		[[Category: Radiation damage]]
	[[Category: Serine hydrolase]]		[[Category: Serine hydrolase]]
	[[Category: Time series]]		[[Category: Time series]]

OCA: Protected "1qid" [edit=sysop:move=sysop]

OCA — Sun, 26 Dec 2010 20:55:20 GMT

Protected "1qid" [edit=sysop:move=sysop]

←Older revision

Revision as of 20:55, 26 December 2010