1qjj - Revision history

OCA at 12:46, 13 December 2023

OCA — Wed, 13 Dec 2023 12:46:49 GMT

←Older revision		Revision as of 12:46, 13 December 2023
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	<StructureSection load='1qjj' size='340' side='right'caption='[[1qjj]], [[Resolution\|resolution]] 1.86Å' scene=''>		<StructureSection load='1qjj' size='340' side='right'caption='[[1qjj]], [[Resolution\|resolution]] 1.86Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1qjj]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Astacus_fluviatilis~~ Astacus ~~fluviatilis~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QJJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1QJJ FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1qjj]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Astacus_astacus Astacus astacus] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QJJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1QJJ FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=ZN:ZINC+ION'>ZN</scene>~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.86Å</td></tr>
-	<tr id='~~NonStdRes~~'><td class="sblockLbl"><b>[[~~Non-Standard_Residue~~\|~~NonStd Res~~:]]</b></td><td class="sblockDat"><scene name='pdbligand=HOA:HYDROXYAMINE'>HOA</scene>~~</td></tr>~~	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=HOA:HYDROXYAMINE'>HOA</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
-	~~<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1ast\|1ast]]~~, ~~[[1iaa\|1iaa]], [[1iab\|1iab]], [[1iac\|1iac]], [[1iad\|1iad]], [[1iae\|1iae]], [[1qji\|1qji]]~~<~~/div></td></tr>~~	+
-	~~<tr id~~='~~activity'><td class~~=~~"sblockLbl"><b>Activity~~:~~</b></td><td class="sblockDat"><span class='plainlinks~~'>~~[https://en.wikipedia.org/wiki/Astacin Astacin], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.24.21 3.4.24.21]~~ </~~span~~></td></tr>	+
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1qjj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1qjj OCA], [https://pdbe.org/1qjj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1qjj RCSB], [https://www.ebi.ac.uk/pdbsum/1qjj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1qjj ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1qjj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1qjj OCA], [https://pdbe.org/1qjj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1qjj RCSB], [https://www.ebi.ac.uk/pdbsum/1qjj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1qjj ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[https://www.uniprot.org/uniprot/ASTA_ASTAS ASTA_ASTAS]] This protease prefers to cleave in front of small aliphatic residues (P1'). The presence of Lys or Arg in the P1 and P2 position yields high-turnover substrates. In the P3 position the enzyme prefers Pro > Val > Leu > Ala > Gly.	+	[https://www.uniprot.org/uniprot/ASTA_ASTAS ASTA_ASTAS] This protease prefers to cleave in front of small aliphatic residues (P1'). The presence of Lys or Arg in the P1 and P2 position yields high-turnover substrates. In the P3 position the enzyme prefers Pro > Val > Leu > Ala > Gly.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
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	==See Also==		==See Also==
-	*[[Proteinase\|Proteinase]]	+	*[[Proteinase 3D structures\|Proteinase 3D structures]]
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	~~[[Category: Astacin]]~~	+	[[Category: Astacus astacus]]
-	[[Category: Astacus ~~fluviatilis~~]]	+
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: ~~Bode, W~~]]	+	[[Category: Synthetic construct]]
-	[[Category: ~~Grams, F]]~~	+	[[Category: Bode W]]
-	~~[[Category: Stocker,~~ W]]	+	[[Category: Grams F]]
-	[[Category: ~~Hydrolase-hydrolase inhibitor complex~~]]	+	[[Category: Stocker W]]
-	[[Category: ~~Metalloproteinase]]~~	+
-	~~[[Category: Metzincin~~]]	+

OCA at 10:27, 17 February 2021

OCA — Wed, 17 Feb 2021 10:27:52 GMT

←Older revision		Revision as of 10:27, 17 February 2021
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	<StructureSection load='1qjj' size='340' side='right'caption='[[1qjj]], [[Resolution\|resolution]] 1.86Å' scene=''>		<StructureSection load='1qjj' size='340' side='right'caption='[[1qjj]], [[Resolution\|resolution]] 1.86Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1qjj]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Astacus_fluviatilis Astacus fluviatilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QJJ OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1QJJ FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1qjj]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Astacus_fluviatilis Astacus fluviatilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QJJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1QJJ FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=HOA:HYDROXYAMINE'>HOA</scene></td></tr>		<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=HOA:HYDROXYAMINE'>HOA</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1ast\|1ast]], [[1iaa\|1iaa]], [[1iab\|1iab]], [[1iac\|1iac]], [[1iad\|1iad]], [[1iae\|1iae]], [[1qji\|1qji]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1ast\|1ast]], [[1iaa\|1iaa]], [[1iab\|1iab]], [[1iac\|1iac]], [[1iad\|1iad]], [[1iae\|1iae]], [[1qji\|1qji]]</div></td></tr>
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://en.wikipedia.org/wiki/Astacin Astacin], with EC number [~~http~~://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.24.21 3.4.24.21] </span></td></tr>	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Astacin Astacin], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.24.21 3.4.24.21] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1qjj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1qjj OCA], [~~http~~://pdbe.org/1qjj PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=1qjj RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/1qjj PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=1qjj ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1qjj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1qjj OCA], [https://pdbe.org/1qjj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1qjj RCSB], [https://www.ebi.ac.uk/pdbsum/1qjj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1qjj ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[~~http~~://www.uniprot.org/uniprot/ASTA_ASTAS ASTA_ASTAS]] This protease prefers to cleave in front of small aliphatic residues (P1'). The presence of Lys or Arg in the P1 and P2 position yields high-turnover substrates. In the P3 position the enzyme prefers Pro > Val > Leu > Ala > Gly.	+	[[https://www.uniprot.org/uniprot/ASTA_ASTAS ASTA_ASTAS]] This protease prefers to cleave in front of small aliphatic residues (P1'). The presence of Lys or Arg in the P1 and P2 position yields high-turnover substrates. In the P3 position the enzyme prefers Pro > Val > Leu > Ala > Gly.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
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	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1qjj ConSurf].		</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1qjj ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
		+
		+	==See Also==
		+	*[[Proteinase\|Proteinase]]
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>

OCA at 11:41, 10 May 2019

OCA — Fri, 10 May 2019 11:41:35 GMT

←Older revision		Revision as of 11:41, 10 May 2019
Line 1:		Line 1:

	==Structure of astacin with a hydroxamic acid inhibitor==		==Structure of astacin with a hydroxamic acid inhibitor==
-	<StructureSection load='1qjj' size='340' side='right' caption='[[1qjj]], [[Resolution\|resolution]] 1.86Å' scene=''>	+	<StructureSection load='1qjj' size='340' side='right'caption='[[1qjj]], [[Resolution\|resolution]] 1.86Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1qjj]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Astacus_fluviatilis Astacus fluviatilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QJJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1QJJ FirstGlance]. <br>		<table><tr><td colspan='2'>[[1qjj]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Astacus_fluviatilis Astacus fluviatilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QJJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1QJJ FirstGlance]. <br>
Line 16:		Line 16:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/qj/1qjj_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/qj/1qjj_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
Line 26:		Line 26:
	[[Category: Astacin]]		[[Category: Astacin]]
	[[Category: Astacus fluviatilis]]		[[Category: Astacus fluviatilis]]
		+	[[Category: Large Structures]]
	[[Category: Bode, W]]		[[Category: Bode, W]]
	[[Category: Grams, F]]		[[Category: Grams, F]]

OCA at 09:27, 2 January 2017

OCA — Mon, 02 Jan 2017 09:27:24 GMT

←Older revision		Revision as of 09:27, 2 January 2017
Line 1:		Line 1:
-	==~~STRUCTURE OF ASTACIN WITH A HYDROXAMIC ACID INHIBITOR~~==	+
		+	==Structure of astacin with a hydroxamic acid inhibitor==
	<StructureSection load='1qjj' size='340' side='right' caption='[[1qjj]], [[Resolution\|resolution]] 1.86Å' scene=''>		<StructureSection load='1qjj' size='340' side='right' caption='[[1qjj]], [[Resolution\|resolution]] 1.86Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1qjj]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Astacus_astacus~~ Astacus ~~astacus~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QJJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1QJJ FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1qjj]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Astacus_fluviatilis Astacus fluviatilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QJJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1QJJ FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=HOA:HYDROXYAMINE'>HOA</scene></td></tr>		<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=HOA:HYDROXYAMINE'>HOA</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1ast\|1ast]], [[1iaa\|1iaa]], [[1iab\|1iab]], [[1iac\|1iac]], [[1iad\|1iad]], [[1iae\|1iae]], [[1qji\|1qji]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1ast\|1ast]], [[1iaa\|1iaa]], [[1iab\|1iab]], [[1iac\|1iac]], [[1iad\|1iad]], [[1iae\|1iae]], [[1qji\|1qji]]</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Astacin Astacin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.24.21 3.4.24.21] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Astacin Astacin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.24.21 3.4.24.21] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1qjj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1qjj OCA], [http://pdbe.org/1qjj PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1qjj RCSB], [http://www.ebi.ac.uk/pdbsum/1qjj PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1qjj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1qjj OCA], [http://pdbe.org/1qjj PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1qjj RCSB], [http://www.ebi.ac.uk/pdbsum/1qjj PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1qjj ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 24:		Line 25:
	</StructureSection>		</StructureSection>
	[[Category: Astacin]]		[[Category: Astacin]]
-	[[Category: Astacus ~~astacus~~]]	+	[[Category: Astacus fluviatilis]]
	[[Category: Bode, W]]		[[Category: Bode, W]]
	[[Category: Grams, F]]		[[Category: Grams, F]]

OCA at 21:05, 7 February 2016

OCA — Sun, 07 Feb 2016 21:05:20 GMT

←Older revision		Revision as of 21:05, 7 February 2016
Line 19:		Line 19:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1qjj ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	__TOC__		__TOC__

OCA at 04:58, 10 September 2015

OCA — Thu, 10 Sep 2015 04:58:57 GMT

←Older revision		Revision as of 04:58, 10 September 2015
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	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1ast\|1ast]], [[1iaa\|1iaa]], [[1iab\|1iab]], [[1iac\|1iac]], [[1iad\|1iad]], [[1iae\|1iae]], [[1qji\|1qji]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1ast\|1ast]], [[1iaa\|1iaa]], [[1iab\|1iab]], [[1iac\|1iac]], [[1iad\|1iad]], [[1iae\|1iae]], [[1qji\|1qji]]</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Astacin Astacin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.24.21 3.4.24.21] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Astacin Astacin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.24.21 3.4.24.21] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1qjj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1qjj OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1qjj RCSB], [http://www.ebi.ac.uk/pdbsum/1qjj PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1qjj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1qjj OCA], [http://pdbe.org/1qjj PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1qjj RCSB], [http://www.ebi.ac.uk/pdbsum/1qjj PDBsum]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[http://www.uniprot.org/uniprot/~~ASTA_ASTFL ASTA_ASTFL~~]] This protease prefers to cleave in front of small aliphatic residues (P1'). The presence of Lys or Arg in the P1 and P2 position yields high-turnover substrates. In the P3 position the enzyme prefers Pro > Val > Leu > Ala > Gly.	+	[[http://www.uniprot.org/uniprot/ASTA_ASTAS ASTA_ASTAS]] This protease prefers to cleave in front of small aliphatic residues (P1'). The presence of Lys or Arg in the P1 and P2 position yields high-turnover substrates. In the P3 position the enzyme prefers Pro > Val > Leu > Ala > Gly.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]

OCA at 18:15, 24 December 2014

OCA — Wed, 24 Dec 2014 18:15:06 GMT

←Older revision		Revision as of 18:15, 24 December 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1qjj]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Astacus_astacus Astacus astacus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QJJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1QJJ FirstGlance]. <br>		<table><tr><td colspan='2'>[[1qjj]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Astacus_astacus Astacus astacus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QJJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1QJJ FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene><br>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
-	<tr><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=HOA:HYDROXYAMINE'>HOA</scene></td></tr>	+	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=HOA:HYDROXYAMINE'>HOA</scene></td></tr>
-	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1ast\|1ast]], [[1iaa\|1iaa]], [[1iab\|1iab]], [[1iac\|1iac]], [[1iad\|1iad]], [[1iae\|1iae]], [[1qji\|1qji]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1ast\|1ast]], [[1iaa\|1iaa]], [[1iab\|1iab]], [[1iac\|1iac]], [[1iad\|1iad]], [[1iae\|1iae]], [[1qji\|1qji]]</td></tr>
-	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Astacin Astacin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.24.21 3.4.24.21] </span></td></tr>	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Astacin Astacin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.24.21 3.4.24.21] </span></td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1qjj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1qjj OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1qjj RCSB], [http://www.ebi.ac.uk/pdbsum/1qjj PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1qjj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1qjj OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1qjj RCSB], [http://www.ebi.ac.uk/pdbsum/1qjj PDBsum]</span></td></tr>
-	<table>	+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/ASTA_ASTFL ASTA_ASTFL]] This protease prefers to cleave in front of small aliphatic residues (P1'). The presence of Lys or Arg in the P1 and P2 position yields high-turnover substrates. In the P3 position the enzyme prefers Pro > Val > Leu > Ala > Gly.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 23:		Line 25:
	[[Category: Astacin]]		[[Category: Astacin]]
	[[Category: Astacus astacus]]		[[Category: Astacus astacus]]
-	[[Category: Bode, W.]]	+	[[Category: Bode, W]]
-	[[Category: Grams, F.]]	+	[[Category: Grams, F]]
-	[[Category: Stocker, W~~.]]~~	+	[[Category: Stocker, W]]
-	~~[[Category: Astacin~~]]	+
	[[Category: Hydrolase-hydrolase inhibitor complex]]		[[Category: Hydrolase-hydrolase inhibitor complex]]
	[[Category: Metalloproteinase]]		[[Category: Metalloproteinase]]
	[[Category: Metzincin]]		[[Category: Metzincin]]

OCA at 14:39, 29 September 2014

OCA — Mon, 29 Sep 2014 14:39:40 GMT

←Older revision		Revision as of 14:39, 29 September 2014
Line 1:		Line 1:
-	~~[[Image:1qjj.png\|left\|200px]]~~	+	==STRUCTURE OF ASTACIN WITH A HYDROXAMIC ACID INHIBITOR==
-		+	<StructureSection load='1qjj' size='340' side='right' caption='[[1qjj]], [[Resolution\|resolution]] 1.86Å' scene=''>
-	~~{{STRUCTURE_1qjj\| PDB=1qjj \| SCENE= }}~~	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[1qjj]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Astacus_astacus Astacus astacus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QJJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1QJJ FirstGlance]. <br>
-	===STRUCTURE OF ASTACIN WITH A HYDROXAMIC ACID INHIBITOR===	+	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene><br>
-		+	<tr><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=HOA:HYDROXYAMINE'>HOA</scene></td></tr>
-		+	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1ast\|1ast]], [[1iaa\|1iaa]], [[1iab\|1iab]], [[1iac\|1iac]], [[1iad\|1iad]], [[1iae\|1iae]], [[1qji\|1qji]]</td></tr>
-	==~~About this Structure~~==	+	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Astacin Astacin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.24.21 3.4.24.21] </span></td></tr>
-	[[1qjj]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Astacus_astacus Astacus astacus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QJJ OCA].	+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1qjj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1qjj OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1qjj RCSB], [http://www.ebi.ac.uk/pdbsum/1qjj PDBsum]</span></td></tr>
-		+	<table>
-	==~~Reference~~==	+	== Evolutionary Conservation ==
-	<~~ref group~~="~~xtra~~">~~PMID~~:~~008756323~~</~~ref~~><~~references group~~="~~xtra~~"/>	+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/qj/1qjj_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	__TOC__
		+	</StructureSection>
	[[Category: Astacin]]		[[Category: Astacin]]
	[[Category: Astacus astacus]]		[[Category: Astacus astacus]]

OCA: Protected "1qjj" [edit=sysop:move=sysop]

OCA — Wed, 02 Jan 2013 09:47:42 GMT

Protected "1qjj" [edit=sysop:move=sysop]

←Older revision

Revision as of 09:47, 2 January 2013

OCA at 09:47, 2 January 2013

OCA — Wed, 02 Jan 2013 09:47:39 GMT

←Older revision		Revision as of 09:47, 2 January 2013
Line 1:		Line 1:
-	{{Seed}}
	[[Image:1qjj.png\|left\|200px]]		[[Image:1qjj.png\|left\|200px]]

-	<!--
-	The line below this paragraph, containing "STRUCTURE_1qjj", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_1qjj\| PDB=1qjj \| SCENE= }}		{{STRUCTURE_1qjj\| PDB=1qjj \| SCENE= }}

Line 14:		Line 7:

	==About this Structure==		==About this Structure==
-	~~1QJJ~~ is a 2 ~~chains~~ structure ~~of sequences~~ from [http://en.wikipedia.org/wiki/Astacus_astacus Astacus astacus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QJJ OCA].	+	[[1qjj]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Astacus_astacus Astacus astacus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QJJ OCA].

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~8756323~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:008756323</ref><references group="xtra"/>
	[[Category: Astacin]]		[[Category: Astacin]]
	[[Category: Astacus astacus]]		[[Category: Astacus astacus]]
Line 24:		Line 17:
	[[Category: Stocker, W.]]		[[Category: Stocker, W.]]
	[[Category: Astacin]]		[[Category: Astacin]]
		+	[[Category: Hydrolase-hydrolase inhibitor complex]]
		+	[[Category: Metalloproteinase]]
	[[Category: Metzincin]]		[[Category: Metzincin]]
-
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 16:30:13 2009''