1qsq - Revision history

OCA at 08:17, 14 February 2024

OCA — Wed, 14 Feb 2024 08:17:13 GMT

←Older revision		Revision as of 08:17, 14 February 2024
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	<StructureSection load='1qsq' size='340' side='right'caption='[[1qsq]], [[Resolution\|resolution]] 1.90Å' scene=''>		<StructureSection load='1qsq' size='340' side='right'caption='[[1qsq]], [[Resolution\|resolution]] 1.90Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1qsq]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Bpt4 Bpt4~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QSQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1QSQ FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1qsq]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_virus_T4 Escherichia virus T4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QSQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1QSQ FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>~~, ~~<scene name='pdbligand=HED:2-HYDROXYETHYL+DISULFIDE'>HED</scene></td></tr>~~	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.9Å</td></tr>
-	~~<tr id='related'><td class="sblockLbl"><b>~~[[~~Related_structure~~\|~~Related:~~]]~~</b></td><td class="sblockDat"><div style='overflow: auto~~; max-height: 3em;'>[[1ctw\|1ctw]], [[1cu0\|1cu0]], [[1cu2\|1cu2]], [[1cu3\|1cu3]], [[1cu6\|1cu6]], [[1cu5\|1cu5]], [[1cup\|1cup]], [[1cuq\|1cuq]], [[1cv0\|1cv0]], [[1cv1\|1cv1]], [[1cv4\|1cv4]], [[1cv3\|1cv3]], [[1cv5\|1cv5]], [[1cv6\|1cv6]], [[1cvk\|1cvk]], [[1d2w\|1d2w]], [[1d2y\|1d2y]], [[1d3f\|1d3f]], [[1d3j\|1d3j]]</div></td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=HED:2-HYDROXYETHYL+DISULFIDE'>HED</scene></td></tr>
-	<tr id='~~gene~~'><td class="sblockLbl"><b>[[~~Gene~~\|~~Gene~~:]]</b></td><td class="sblockDat"~~>GENE E ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&~~id=~~10665 BPT4])</td~~><~~/tr>~~	+
-	~~<tr id~~='~~activity'><td class~~=~~"sblockLbl"><b>Activity~~:~~</b~~></td><~~td class~~=~~"sblockDat"><span class~~=~~'plainlinks~~'>~~[https://en.wikipedia.org/wiki/Lysozyme Lysozyme], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.17 3.2.1.17]~~ </~~span~~></td></tr>	+
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1qsq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1qsq OCA], [https://pdbe.org/1qsq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1qsq RCSB], [https://www.ebi.ac.uk/pdbsum/1qsq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1qsq ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1qsq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1qsq OCA], [https://pdbe.org/1qsq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1qsq RCSB], [https://www.ebi.ac.uk/pdbsum/1qsq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1qsq ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[https://www.uniprot.org/uniprot/~~LYS_BPT4 LYS_BPT4~~]~~] Helps~~ to ~~release~~ the mature ~~phage~~ particles ~~from~~ the cell ~~wall by breaking~~ down the peptidoglycan.	+	[https://www.uniprot.org/uniprot/ENLYS_BPT4 ENLYS_BPT4] Endolysin with lysozyme activity that degrades host peptidoglycans and participates with the holin and spanin proteins in the sequential events which lead to the programmed host cell lysis releasing the mature viral particles. Once the holin has permeabilized the host cell membrane, the endolysin can reach the periplasm and break down the peptidoglycan layer.<ref>PMID:22389108</ref>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
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	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1qsq ConSurf].		</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1qsq ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
-	<div style="background-color:#fffaf0;">
-	== Publication Abstract from PubMed ==
-	In an attempt to identify a systematic relation between the structure of a protein and its folding kinetics, the rate of folding was determined for 20 mutants of T4 lysozyme in which a bulky, buried, nonpolar wild-type residue (Leu, Ile, Phe, Val, or Met) was substituted with alanine. Methionine, which approximated the size of the original side chain but which is of different shape and flexibility, was also substituted at most of the same sites. Mutations that substantially destabilize the protein and are located in the carboxy-terminal domain generally slow the rate of folding. Destabilizing mutations in the amino-terminal domain, however, have little effect on the rate of folding. Mutations that have little effect on stability tend to have little effect on the rate, no matter where they are located. These results suggest that, at the rate-limiting step, elements of structure in the C-terminal domain are formed and have a structure similar to that of the fully folded protein. Consistent with this, two variants that somewhat increase the rate of folding (Phe104 --> Met and Val149 --> Met) are located within the carboxy-terminal domain and maintain or improve packing with very little perturbation of the wild-type structure.
-
-	Methionine and alanine substitutions show that the formation of wild-type-like structure in the carboxy-terminal domain of T4 lysozyme is a rate-limiting step in folding.,Gassner NC, Baase WA, Lindstrom JD, Lu J, Dahlquist FW, Matthews BW Biochemistry. 1999 Nov 2;38(44):14451-60. PMID:10545167<ref>PMID:10545167</ref>
-
-	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	</div>
-	<div class="pdbe-citations 1qsq" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Bpt4~~]]	+	[[Category: Escherichia virus T4]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	~~[[Category: Lysozyme]]~~	+	[[Category: Baase WA]]
-	[[Category: Baase~~, W A~~]]	+	[[Category: Gassner NC]]
-	[[Category: Gassner~~, N C~~]]	+	[[Category: Lindstrom J]]
-	[[Category: Lindstrom, J]]	+	[[Category: Matthews BW]]
-	[[Category: Matthews~~, B W]]~~	+
-	~~[[Category: Cavity mutant]]~~	+
-	~~[[Category: Hydrolase]]~~	+
-	~~[[Category: Protein engineering]]~~	+
-	~~[[Category: Protein folding]]~~	+
-	~~[[Category: T4 lysozyme~~]]	+

OCA at 15:27, 3 November 2021

OCA — Wed, 03 Nov 2021 15:27:40 GMT

OCA at 13:12, 16 December 2020

OCA — Wed, 16 Dec 2020 13:12:00 GMT

←Older revision		Revision as of 13:12, 16 December 2020
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	==CAVITY CREATING MUTATION==		==CAVITY CREATING MUTATION==
-	<StructureSection load='1qsq' size='340' side='right' caption='[[1qsq]], [[Resolution\|resolution]] 1.90Å' scene=''>	+	<StructureSection load='1qsq' size='340' side='right'caption='[[1qsq]], [[Resolution\|resolution]] 1.90Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1qsq]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Bpt4 Bpt4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QSQ OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1QSQ FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1qsq]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Bpt4 Bpt4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QSQ OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=1QSQ FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=HED:2-HYDROXYETHYL+DISULFIDE'>HED</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=HED:2-HYDROXYETHYL+DISULFIDE'>HED</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1ctw\|1ctw]], [[1cu0\|1cu0]], [[1cu2\|1cu2]], [[1cu3\|1cu3]], [[1cu6\|1cu6]], [[1cu5\|1cu5]], [[1cup\|1cup]], [[1cuq\|1cuq]], [[1cv0\|1cv0]], [[1cv1\|1cv1]], [[1cv4\|1cv4]], [[1cv3\|1cv3]], [[1cv5\|1cv5]], [[1cv6\|1cv6]], [[1cvk\|1cvk]], [[1d2w\|1d2w]], [[1d2y\|1d2y]], [[1d3f\|1d3f]], [[1d3j\|1d3j]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1ctw\|1ctw]], [[1cu0\|1cu0]], [[1cu2\|1cu2]], [[1cu3\|1cu3]], [[1cu6\|1cu6]], [[1cu5\|1cu5]], [[1cup\|1cup]], [[1cuq\|1cuq]], [[1cv0\|1cv0]], [[1cv1\|1cv1]], [[1cv4\|1cv4]], [[1cv3\|1cv3]], [[1cv5\|1cv5]], [[1cv6\|1cv6]], [[1cvk\|1cvk]], [[1d2w\|1d2w]], [[1d2y\|1d2y]], [[1d3f\|1d3f]], [[1d3j\|1d3j]]</div></td></tr>
	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">GENE E ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10665 BPT4])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">GENE E ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10665 BPT4])</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Lysozyme Lysozyme], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.17 3.2.1.17] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Lysozyme Lysozyme], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.17 3.2.1.17] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1qsq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1qsq OCA], [http://pdbe.org/1qsq PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1qsq RCSB], [http://www.ebi.ac.uk/pdbsum/1qsq PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1qsq ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=1qsq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1qsq OCA], [http://pdbe.org/1qsq PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1qsq RCSB], [http://www.ebi.ac.uk/pdbsum/1qsq PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1qsq ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 31:		Line 31:
	</div>		</div>
	<div class="pdbe-citations 1qsq" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 1qsq" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[Lysozyme 3D structures\|Lysozyme 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
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	</StructureSection>		</StructureSection>
	[[Category: Bpt4]]		[[Category: Bpt4]]
		+	[[Category: Large Structures]]
	[[Category: Lysozyme]]		[[Category: Lysozyme]]
	[[Category: Baase, W A]]		[[Category: Baase, W A]]

OCA at 06:29, 31 January 2018

OCA — Wed, 31 Jan 2018 06:29:42 GMT

←Older revision		Revision as of 06:29, 31 January 2018
Line 1:		Line 1:
		+
	==CAVITY CREATING MUTATION==		==CAVITY CREATING MUTATION==
	<StructureSection load='1qsq' size='340' side='right' caption='[[1qsq]], [[Resolution\|resolution]] 1.90Å' scene=''>		<StructureSection load='1qsq' size='340' side='right' caption='[[1qsq]], [[Resolution\|resolution]] 1.90Å' scene=''>
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	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">GENE E ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10665 BPT4])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">GENE E ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10665 BPT4])</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Lysozyme Lysozyme], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.17 3.2.1.17] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Lysozyme Lysozyme], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.17 3.2.1.17] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1qsq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1qsq OCA], [http://pdbe.org/1qsq PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1qsq RCSB], [http://www.ebi.ac.uk/pdbsum/1qsq PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1qsq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1qsq OCA], [http://pdbe.org/1qsq PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1qsq RCSB], [http://www.ebi.ac.uk/pdbsum/1qsq PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1qsq ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 15:		Line 16:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/qs/1qsq_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/qs/1qsq_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
Line 30:		Line 31:
	</div>		</div>
	<div class="pdbe-citations 1qsq" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 1qsq" style="background-color:#fffaf0;"></div>
-
-	==See Also==
-	*[[Lysozyme 3D structures\|Lysozyme 3D structures]]
	== References ==		== References ==
	<references/>		<references/>

OCA at 08:32, 7 February 2016

OCA — Sun, 07 Feb 2016 08:32:00 GMT

←Older revision		Revision as of 08:32, 7 February 2016
Line 19:		Line 19:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1qsq ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 23:39, 9 September 2015

OCA — Wed, 09 Sep 2015 23:39:46 GMT

←Older revision		Revision as of 23:39, 9 September 2015
Line 2:		Line 2:
	<StructureSection load='1qsq' size='340' side='right' caption='[[1qsq]], [[Resolution\|resolution]] 1.90Å' scene=''>		<StructureSection load='1qsq' size='340' side='right' caption='[[1qsq]], [[Resolution\|resolution]] 1.90Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1qsq]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Enterobacteria_phage_t4 Enterobacteria phage t4~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QSQ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1QSQ FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1qsq]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Bpt4 Bpt4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QSQ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1QSQ FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=HED:2-HYDROXYETHYL+DISULFIDE'>HED</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=HED:2-HYDROXYETHYL+DISULFIDE'>HED</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1ctw\|1ctw]], [[1cu0\|1cu0]], [[1cu2\|1cu2]], [[1cu3\|1cu3]], [[1cu6\|1cu6]], [[1cu5\|1cu5]], [[1cup\|1cup]], [[1cuq\|1cuq]], [[1cv0\|1cv0]], [[1cv1\|1cv1]], [[1cv4\|1cv4]], [[1cv3\|1cv3]], [[1cv5\|1cv5]], [[1cv6\|1cv6]], [[1cvk\|1cvk]], [[1d2w\|1d2w]], [[1d2y\|1d2y]], [[1d3f\|1d3f]], [[1d3j\|1d3j]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1ctw\|1ctw]], [[1cu0\|1cu0]], [[1cu2\|1cu2]], [[1cu3\|1cu3]], [[1cu6\|1cu6]], [[1cu5\|1cu5]], [[1cup\|1cup]], [[1cuq\|1cuq]], [[1cv0\|1cv0]], [[1cv1\|1cv1]], [[1cv4\|1cv4]], [[1cv3\|1cv3]], [[1cv5\|1cv5]], [[1cv6\|1cv6]], [[1cvk\|1cvk]], [[1d2w\|1d2w]], [[1d2y\|1d2y]], [[1d3f\|1d3f]], [[1d3j\|1d3j]]</td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">GENE E ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10665 ~~Enterobacteria phage T4~~])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">GENE E ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10665 BPT4])</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Lysozyme Lysozyme], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.17 3.2.1.17] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Lysozyme Lysozyme], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.17 3.2.1.17] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1qsq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1qsq OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1qsq RCSB], [http://www.ebi.ac.uk/pdbsum/1qsq PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1qsq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1qsq OCA], [http://pdbe.org/1qsq PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1qsq RCSB], [http://www.ebi.ac.uk/pdbsum/1qsq PDBsum]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 29:		Line 29:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 1qsq" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
Line 36:		Line 37:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Enterobacteria phage t4~~]]	+	[[Category: Bpt4]]
	[[Category: Lysozyme]]		[[Category: Lysozyme]]
	[[Category: Baase, W A]]		[[Category: Baase, W A]]

OCA at 13:40, 24 December 2014

OCA — Wed, 24 Dec 2014 13:40:34 GMT

←Older revision		Revision as of 13:40, 24 December 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1qsq]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Enterobacteria_phage_t4 Enterobacteria phage t4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QSQ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1QSQ FirstGlance]. <br>		<table><tr><td colspan='2'>[[1qsq]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Enterobacteria_phage_t4 Enterobacteria phage t4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QSQ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1QSQ FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=HED:2-HYDROXYETHYL+DISULFIDE'>HED</scene><br>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=HED:2-HYDROXYETHYL+DISULFIDE'>HED</scene></td></tr>
-	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1ctw\|1ctw]], [[1cu0\|1cu0]], [[1cu2\|1cu2]], [[1cu3\|1cu3]], [[1cu6\|1cu6]], [[1cu5\|1cu5]], [[1cup\|1cup]], [[1cuq\|1cuq]], [[1cv0\|1cv0]], [[1cv1\|1cv1]], [[1cv4\|1cv4]], [[1cv3\|1cv3]], [[1cv5\|1cv5]], [[1cv6\|1cv6]], [[1cvk\|1cvk]], [[1d2w\|1d2w]], [[1d2y\|1d2y]], [[1d3f\|1d3f]], [[1d3j\|1d3j]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1ctw\|1ctw]], [[1cu0\|1cu0]], [[1cu2\|1cu2]], [[1cu3\|1cu3]], [[1cu6\|1cu6]], [[1cu5\|1cu5]], [[1cup\|1cup]], [[1cuq\|1cuq]], [[1cv0\|1cv0]], [[1cv1\|1cv1]], [[1cv4\|1cv4]], [[1cv3\|1cv3]], [[1cv5\|1cv5]], [[1cv6\|1cv6]], [[1cvk\|1cvk]], [[1d2w\|1d2w]], [[1d2y\|1d2y]], [[1d3f\|1d3f]], [[1d3j\|1d3j]]</td></tr>
-	<tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">GENE E ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10665 Enterobacteria phage T4])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">GENE E ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10665 Enterobacteria phage T4])</td></tr>
-	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Lysozyme Lysozyme], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.17 3.2.1.17] </span></td></tr>	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Lysozyme Lysozyme], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.17 3.2.1.17] </span></td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1qsq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1qsq OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1qsq RCSB], [http://www.ebi.ac.uk/pdbsum/1qsq PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1qsq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1qsq OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1qsq RCSB], [http://www.ebi.ac.uk/pdbsum/1qsq PDBsum]</span></td></tr>
-	<table>	+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/LYS_BPT4 LYS_BPT4]] Helps to release the mature phage particles from the cell wall by breaking down the peptidoglycan.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 36:		Line 38:
	[[Category: Enterobacteria phage t4]]		[[Category: Enterobacteria phage t4]]
	[[Category: Lysozyme]]		[[Category: Lysozyme]]
-	[[Category: Baase, W A.]]	+	[[Category: Baase, W A]]
-	[[Category: Gassner, N C.]]	+	[[Category: Gassner, N C]]
-	[[Category: Lindstrom, J.]]	+	[[Category: Lindstrom, J]]
-	[[Category: Matthews, B W.]]	+	[[Category: Matthews, B W]]
	[[Category: Cavity mutant]]		[[Category: Cavity mutant]]
	[[Category: Hydrolase]]		[[Category: Hydrolase]]

OCA at 21:37, 28 September 2014

OCA — Sun, 28 Sep 2014 21:37:36 GMT

←Older revision		Revision as of 21:37, 28 September 2014
Line 1:		Line 1:
-	[[~~Image:~~1qsq.~~png~~\|~~left~~\|200px]]	+	==CAVITY CREATING MUTATION==
		+	<StructureSection load='1qsq' size='340' side='right' caption='[[1qsq]], [[Resolution\|resolution]] 1.90Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[1qsq]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Enterobacteria_phage_t4 Enterobacteria phage t4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QSQ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1QSQ FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=HED:2-HYDROXYETHYL+DISULFIDE'>HED</scene><br>
		+	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1ctw\|1ctw]], [[1cu0\|1cu0]], [[1cu2\|1cu2]], [[1cu3\|1cu3]], [[1cu6\|1cu6]], [[1cu5\|1cu5]], [[1cup\|1cup]], [[1cuq\|1cuq]], [[1cv0\|1cv0]], [[1cv1\|1cv1]], [[1cv4\|1cv4]], [[1cv3\|1cv3]], [[1cv5\|1cv5]], [[1cv6\|1cv6]], [[1cvk\|1cvk]], [[1d2w\|1d2w]], [[1d2y\|1d2y]], [[1d3f\|1d3f]], [[1d3j\|1d3j]]</td></tr>
		+	<tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">GENE E ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10665 Enterobacteria phage T4])</td></tr>
		+	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Lysozyme Lysozyme], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.17 3.2.1.17] </span></td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1qsq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1qsq OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1qsq RCSB], [http://www.ebi.ac.uk/pdbsum/1qsq PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/qs/1qsq_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	In an attempt to identify a systematic relation between the structure of a protein and its folding kinetics, the rate of folding was determined for 20 mutants of T4 lysozyme in which a bulky, buried, nonpolar wild-type residue (Leu, Ile, Phe, Val, or Met) was substituted with alanine. Methionine, which approximated the size of the original side chain but which is of different shape and flexibility, was also substituted at most of the same sites. Mutations that substantially destabilize the protein and are located in the carboxy-terminal domain generally slow the rate of folding. Destabilizing mutations in the amino-terminal domain, however, have little effect on the rate of folding. Mutations that have little effect on stability tend to have little effect on the rate, no matter where they are located. These results suggest that, at the rate-limiting step, elements of structure in the C-terminal domain are formed and have a structure similar to that of the fully folded protein. Consistent with this, two variants that somewhat increase the rate of folding (Phe104 --> Met and Val149 --> Met) are located within the carboxy-terminal domain and maintain or improve packing with very little perturbation of the wild-type structure.

-	~~{{STRUCTURE_1qsq\| PDB=1qsq \| SCENE= }}~~	+	Methionine and alanine substitutions show that the formation of wild-type-like structure in the carboxy-terminal domain of T4 lysozyme is a rate-limiting step in folding.,Gassner NC, Baase WA, Lindstrom JD, Lu J, Dahlquist FW, Matthews BW Biochemistry. 1999 Nov 2;38(44):14451-60. PMID:10545167<ref>PMID:10545167</ref>

-	~~===CAVITY CREATING MUTATION===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_10545167}}~~	+
-		+
-	~~==About this Structure==~~	+
-	~~[[1qsq]] is~~ a ~~1 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Enterobacteria_phage_t4 Enterobacteria phage t4]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=1QSQ OCA].~~	+

	==See Also==		==See Also==
-	*[[~~Hen Egg-White (HEW)~~ Lysozyme\|~~Hen Egg-White (HEW)~~ Lysozyme]]	+	*[[Lysozyme 3D structures\|Lysozyme 3D structures]]
-		+	== References ==
-	==~~Reference~~==	+	<references/>
-	<~~ref group="xtra">PMID:010545167<~~/~~ref~~><~~references group="xtra"~~/>	+	__TOC__
		+	</StructureSection>
	[[Category: Enterobacteria phage t4]]		[[Category: Enterobacteria phage t4]]
	[[Category: Lysozyme]]		[[Category: Lysozyme]]

OCA at 06:07, 20 October 2012

OCA — Sat, 20 Oct 2012 06:07:09 GMT

←Older revision		Revision as of 06:07, 20 October 2012
Line 8:		Line 8:

	==About this Structure==		==About this Structure==
-	[[1qsq]] is a 1 chain structure ~~of [[Hen Egg-White (HEW) Lysozyme]]~~ with sequence from [http://en.wikipedia.org/wiki/Enterobacteria_phage_t4 Enterobacteria phage t4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QSQ OCA].	+	[[1qsq]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Enterobacteria_phage_t4 Enterobacteria phage t4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QSQ OCA].

	==See Also==		==See Also==

OCA: Protected "1qsq" [edit=sysop:move=sysop]

OCA — Wed, 25 Jul 2012 12:10:46 GMT

Protected "1qsq" [edit=sysop:move=sysop]

←Older revision

Revision as of 12:10, 25 July 2012

←Older revision		Revision as of 15:27, 3 November 2021
Line 3:		Line 3:
	<StructureSection load='1qsq' size='340' side='right'caption='[[1qsq]], [[Resolution\|resolution]] 1.90Å' scene=''>		<StructureSection load='1qsq' size='340' side='right'caption='[[1qsq]], [[Resolution\|resolution]] 1.90Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1qsq]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Bpt4 Bpt4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QSQ OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=1QSQ FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1qsq]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Bpt4 Bpt4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QSQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1QSQ FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=HED:2-HYDROXYETHYL+DISULFIDE'>HED</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=HED:2-HYDROXYETHYL+DISULFIDE'>HED</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1ctw\|1ctw]], [[1cu0\|1cu0]], [[1cu2\|1cu2]], [[1cu3\|1cu3]], [[1cu6\|1cu6]], [[1cu5\|1cu5]], [[1cup\|1cup]], [[1cuq\|1cuq]], [[1cv0\|1cv0]], [[1cv1\|1cv1]], [[1cv4\|1cv4]], [[1cv3\|1cv3]], [[1cv5\|1cv5]], [[1cv6\|1cv6]], [[1cvk\|1cvk]], [[1d2w\|1d2w]], [[1d2y\|1d2y]], [[1d3f\|1d3f]], [[1d3j\|1d3j]]</div></td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1ctw\|1ctw]], [[1cu0\|1cu0]], [[1cu2\|1cu2]], [[1cu3\|1cu3]], [[1cu6\|1cu6]], [[1cu5\|1cu5]], [[1cup\|1cup]], [[1cuq\|1cuq]], [[1cv0\|1cv0]], [[1cv1\|1cv1]], [[1cv4\|1cv4]], [[1cv3\|1cv3]], [[1cv5\|1cv5]], [[1cv6\|1cv6]], [[1cvk\|1cvk]], [[1d2w\|1d2w]], [[1d2y\|1d2y]], [[1d3f\|1d3f]], [[1d3j\|1d3j]]</div></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">GENE E ([~~http~~://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10665 BPT4])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">GENE E ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10665 BPT4])</td></tr>
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://en.wikipedia.org/wiki/Lysozyme Lysozyme], with EC number [~~http~~://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.17 3.2.1.17] </span></td></tr>	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Lysozyme Lysozyme], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.17 3.2.1.17] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=1qsq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1qsq OCA], [~~http~~://pdbe.org/1qsq PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=1qsq RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/1qsq PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=1qsq ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1qsq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1qsq OCA], [https://pdbe.org/1qsq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1qsq RCSB], [https://www.ebi.ac.uk/pdbsum/1qsq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1qsq ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[~~http~~://www.uniprot.org/uniprot/LYS_BPT4 LYS_BPT4]] Helps to release the mature phage particles from the cell wall by breaking down the peptidoglycan.	+	[[https://www.uniprot.org/uniprot/LYS_BPT4 LYS_BPT4]] Helps to release the mature phage particles from the cell wall by breaking down the peptidoglycan.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]