1rz2 - Revision history

OCA at 08:27, 14 February 2024

OCA — Wed, 14 Feb 2024 08:27:04 GMT

←Older revision		Revision as of 08:27, 14 February 2024
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	<StructureSection load='1rz2' size='340' side='right'caption='[[1rz2]], [[Resolution\|resolution]] 1.60Å' scene=''>		<StructureSection load='1rz2' size='340' side='right'caption='[[1rz2]], [[Resolution\|resolution]] 1.60Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1rz2]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Bacillus_anthracis_(strain_ames)~~ Bacillus anthracis ~~(strain ames)~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1RZ2 OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=1RZ2 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1rz2]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_anthracis_str._Ames Bacillus anthracis str. Ames]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1RZ2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1RZ2 FirstGlance]. <br>
-	</td></tr><tr id='~~related~~'><td class="sblockLbl"><b>[[~~Related_structure~~\|~~Related~~:]]</b></td><td class="sblockDat"~~><div style='overflow: auto; max-height: 3em;'>[[1ng5\|1ng5]]</div></td></tr>~~	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.6Å</td></tr>
-	~~<tr~~ id~~='gene'><td class~~="~~sblockLbl~~">~~<b>~~[[~~Gene~~\|~~Gene:~~]]~~</b></td><td class="sblockDat">BA4783 ([http://www~~.~~ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info~~&~~srchmode=5&id=198094 Bacillus anthracis (strain Ames)])~~</td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1rz2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1rz2 OCA], [https://pdbe.org/1rz2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1rz2 RCSB], [https://www.ebi.ac.uk/pdbsum/1rz2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1rz2 ProSAT], [https://www.topsan.org/Proteins/MCSG/1rz2 TOPSAN]</span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=1rz2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1rz2 OCA], [~~http~~://pdbe.org/1rz2 PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=1rz2 RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/1rz2 PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=1rz2 ProSAT], [~~http~~://www.topsan.org/Proteins/MCSG/1rz2 TOPSAN]</span></td></tr>	+
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/A0A6L8PZR0_BACAN A0A6L8PZR0_BACAN]
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
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	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1rz2 ConSurf].		</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1rz2 ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
-	<div style="background-color:#fffaf0;">
-	== Publication Abstract from PubMed ==
-	Surface proteins attached by sortases to the cell wall envelope of bacterial pathogens play important roles during infection. Sorting and attachment of these proteins is directed by C-terminal signals. Sortase B of S. aureus recognizes a motif NPQTN, cleaves the polypeptide after the Thr residue, and attaches the protein to pentaglycine cross-bridges. Sortase B of B. anthracis is thought to recognize the NPKTG motif, and attaches surface proteins to m-diaminopimelic acid cross-bridges. We have determined crystal structure of sortase B from B. anthracis and S. aureus at 1.6 and 2.0 A resolutions, respectively. These structures show a beta-barrel fold with alpha-helical elements on its outside, a structure thus far exclusive to the sortase family. A putative active site located on the edge of the beta-barrel is comprised of a Cys-His-Asp catalytic triad and presumably faces the bacterial cell surface. A putative binding site for the sorting signal is located nearby.
-
-	Structures of sortase B from Staphylococcus aureus and Bacillus anthracis reveal catalytic amino acid triad in the active site.,Zhang R, Wu R, Joachimiak G, Mazmanian SK, Missiakas DM, Gornicki P, Schneewind O, Joachimiak A Structure. 2004 Jul;12(7):1147-56. PMID:15242591<ref>PMID:15242591</ref>
-
-	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	</div>
-	<div class="pdbe-citations 1rz2" style="background-color:#fffaf0;"></div>
-	== References ==
-	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Bacillus anthracis str. Ames]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Gornicki, P]]	+	[[Category: Gornicki P]]
-	[[Category: Joachimiak, A]]	+	[[Category: Joachimiak A]]
-	~~[[Category: Structural genomic~~]]	+	[[Category: Wu R]]
-	[[Category: Wu, R]]	+	[[Category: Zhang R]]
-	[[Category: Zhang, R]]	+
-	~~[[Category: B. anthracis]]~~	+
-	~~[[Category: Mcsg]]~~	+
-	~~[[Category: PSI, Protein structure initiative]]~~	+
-	~~[[Category: Sortase b protein]]~~	+
-	~~[[Category: Unknown function~~]]	+

OCA at 13:36, 16 December 2020

OCA — Wed, 16 Dec 2020 13:36:42 GMT

←Older revision		Revision as of 13:36, 16 December 2020
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	==1.6A crystal structure of the protein BA4783/Q81L49 (similar to sortase B) from Bacillus anthracis.==		==1.6A crystal structure of the protein BA4783/Q81L49 (similar to sortase B) from Bacillus anthracis.==
-	<StructureSection load='1rz2' size='340' side='right' caption='[[1rz2]], [[Resolution\|resolution]] 1.60Å' scene=''>	+	<StructureSection load='1rz2' size='340' side='right'caption='[[1rz2]], [[Resolution\|resolution]] 1.60Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1rz2]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacillus_anthracis_(strain_ames) Bacillus anthracis (strain ames)]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1RZ2 OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1RZ2 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1rz2]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacillus_anthracis_(strain_ames) Bacillus anthracis (strain ames)]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1RZ2 OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=1RZ2 FirstGlance]. <br>
-	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1ng5\|1ng5]]</td></tr>	+	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1ng5\|1ng5]]</div></td></tr>
	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">BA4783 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=198094 Bacillus anthracis (strain Ames)])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">BA4783 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=198094 Bacillus anthracis (strain Ames)])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1rz2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1rz2 OCA], [http://pdbe.org/1rz2 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1rz2 RCSB], [http://www.ebi.ac.uk/pdbsum/1rz2 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1rz2 ProSAT], [http://www.topsan.org/Proteins/MCSG/1rz2 TOPSAN]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=1rz2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1rz2 OCA], [http://pdbe.org/1rz2 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1rz2 RCSB], [http://www.ebi.ac.uk/pdbsum/1rz2 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1rz2 ProSAT], [http://www.topsan.org/Proteins/MCSG/1rz2 TOPSAN]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Large Structures]]
	[[Category: Gornicki, P]]		[[Category: Gornicki, P]]
	[[Category: Joachimiak, A]]		[[Category: Joachimiak, A]]

OCA at 07:17, 8 March 2018

OCA — Thu, 08 Mar 2018 07:17:30 GMT

←Older revision		Revision as of 07:17, 8 March 2018
Line 1:		Line 1:
		+
	==1.6A crystal structure of the protein BA4783/Q81L49 (similar to sortase B) from Bacillus anthracis.==		==1.6A crystal structure of the protein BA4783/Q81L49 (similar to sortase B) from Bacillus anthracis.==
	<StructureSection load='1rz2' size='340' side='right' caption='[[1rz2]], [[Resolution\|resolution]] 1.60Å' scene=''>		<StructureSection load='1rz2' size='340' side='right' caption='[[1rz2]], [[Resolution\|resolution]] 1.60Å' scene=''>
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	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1ng5\|1ng5]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1ng5\|1ng5]]</td></tr>
	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">BA4783 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=198094 Bacillus anthracis (strain Ames)])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">BA4783 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=198094 Bacillus anthracis (strain Ames)])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1rz2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1rz2 OCA], [http://pdbe.org/1rz2 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1rz2 RCSB], [http://www.ebi.ac.uk/pdbsum/1rz2 PDBsum], [http://www.topsan.org/Proteins/MCSG/1rz2 TOPSAN]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1rz2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1rz2 OCA], [http://pdbe.org/1rz2 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1rz2 RCSB], [http://www.ebi.ac.uk/pdbsum/1rz2 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1rz2 ProSAT], [http://www.topsan.org/Proteins/MCSG/1rz2 TOPSAN]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 11:		Line 12:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/rz/1rz2_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/rz/1rz2_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>

OCA at 21:01, 8 February 2016

OCA — Mon, 08 Feb 2016 21:01:06 GMT

←Older revision		Revision as of 21:01, 8 February 2016
Line 15:		Line 15:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1rz2 ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 15:20, 10 September 2015

OCA — Thu, 10 Sep 2015 15:20:51 GMT

←Older revision		Revision as of 15:20, 10 September 2015
Line 2:		Line 2:
	<StructureSection load='1rz2' size='340' side='right' caption='[[1rz2]], [[Resolution\|resolution]] 1.60Å' scene=''>		<StructureSection load='1rz2' size='340' side='right' caption='[[1rz2]], [[Resolution\|resolution]] 1.60Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1rz2]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Bacillus_anthracis~~ Bacillus anthracis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1RZ2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1RZ2 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1rz2]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacillus_anthracis_(strain_ames) Bacillus anthracis (strain ames)]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1RZ2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1RZ2 FirstGlance]. <br>
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1ng5\|1ng5]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1ng5\|1ng5]]</td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">BA4783 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=~~1392~~ Bacillus anthracis])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">BA4783 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=198094 Bacillus anthracis (strain Ames)])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1rz2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1rz2 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1rz2 RCSB], [http://www.ebi.ac.uk/pdbsum/1rz2 PDBsum], [http://www.topsan.org/Proteins/MCSG/1rz2 TOPSAN]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1rz2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1rz2 OCA], [http://pdbe.org/1rz2 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1rz2 RCSB], [http://www.ebi.ac.uk/pdbsum/1rz2 PDBsum], [http://www.topsan.org/Proteins/MCSG/1rz2 TOPSAN]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 25:		Line 25:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 1rz2" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Bacillus anthracis]]
	[[Category: Gornicki, P]]		[[Category: Gornicki, P]]
	[[Category: Joachimiak, A]]		[[Category: Joachimiak, A]]

OCA at 02:07, 25 December 2014

OCA — Thu, 25 Dec 2014 02:07:05 GMT

←Older revision		Revision as of 02:07, 25 December 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1rz2]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacillus_anthracis Bacillus anthracis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1RZ2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1RZ2 FirstGlance]. <br>		<table><tr><td colspan='2'>[[1rz2]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacillus_anthracis Bacillus anthracis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1RZ2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1RZ2 FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1ng5\|1ng5]]</td></tr>	+	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1ng5\|1ng5]]</td></tr>
-	<tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">BA4783 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1392 Bacillus anthracis])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">BA4783 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1392 Bacillus anthracis])</td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1rz2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1rz2 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1rz2 RCSB], [http://www.ebi.ac.uk/pdbsum/1rz2 PDBsum], [http://www.topsan.org/Proteins/MCSG/1rz2 TOPSAN]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1rz2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1rz2 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1rz2 RCSB], [http://www.ebi.ac.uk/pdbsum/1rz2 PDBsum], [http://www.topsan.org/Proteins/MCSG/1rz2 TOPSAN]</span></td></tr>
-	<table>	+	</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
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	</StructureSection>		</StructureSection>
	[[Category: Bacillus anthracis]]		[[Category: Bacillus anthracis]]
-	[[Category: Gornicki, P.]]	+	[[Category: Gornicki, P]]
-	[[Category: Joachimiak, A.]]	+	[[Category: Joachimiak, A]]
-	[[Category: ~~MCSG, Midwest Center for~~ Structural ~~Genomics.~~]]	+	[[Category: Structural genomic]]
-	[[Category: Wu, R.]]	+	[[Category: Wu, R]]
-	[[Category: Zhang, R.]]	+	[[Category: Zhang, R]]
	[[Category: B. anthracis]]		[[Category: B. anthracis]]
	[[Category: Mcsg]]		[[Category: Mcsg]]
-	[[Category: ~~Midwest center for structural genomic]]~~	+	[[Category: PSI, Protein structure initiative]]
-	~~[[Category:~~ Protein structure initiative]]	+
-	~~[[Category: Psi~~]]	+
	[[Category: Sortase b protein]]		[[Category: Sortase b protein]]
-	[[Category: Structural genomic]]
	[[Category: Unknown function]]		[[Category: Unknown function]]

OCA at 17:12, 29 September 2014

OCA — Mon, 29 Sep 2014 17:12:54 GMT

←Older revision		Revision as of 17:12, 29 September 2014
Line 1:		Line 1:
-	[[~~Image:~~1rz2.~~png~~\|~~left~~\|200px]]	+	==1.6A crystal structure of the protein BA4783/Q81L49 (similar to sortase B) from Bacillus anthracis.==
		+	<StructureSection load='1rz2' size='340' side='right' caption='[[1rz2]], [[Resolution\|resolution]] 1.60Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[1rz2]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacillus_anthracis Bacillus anthracis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1RZ2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1RZ2 FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1ng5\|1ng5]]</td></tr>
		+	<tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">BA4783 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1392 Bacillus anthracis])</td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1rz2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1rz2 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1rz2 RCSB], [http://www.ebi.ac.uk/pdbsum/1rz2 PDBsum], [http://www.topsan.org/Proteins/MCSG/1rz2 TOPSAN]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/rz/1rz2_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Surface proteins attached by sortases to the cell wall envelope of bacterial pathogens play important roles during infection. Sorting and attachment of these proteins is directed by C-terminal signals. Sortase B of S. aureus recognizes a motif NPQTN, cleaves the polypeptide after the Thr residue, and attaches the protein to pentaglycine cross-bridges. Sortase B of B. anthracis is thought to recognize the NPKTG motif, and attaches surface proteins to m-diaminopimelic acid cross-bridges. We have determined crystal structure of sortase B from B. anthracis and S. aureus at 1.6 and 2.0 A resolutions, respectively. These structures show a beta-barrel fold with alpha-helical elements on its outside, a structure thus far exclusive to the sortase family. A putative active site located on the edge of the beta-barrel is comprised of a Cys-His-Asp catalytic triad and presumably faces the bacterial cell surface. A putative binding site for the sorting signal is located nearby.

-	~~{{STRUCTURE_1rz2\| PDB=1rz2 \| SCENE= }}~~	+	Structures of sortase B from Staphylococcus aureus and Bacillus anthracis reveal catalytic amino acid triad in the active site.,Zhang R, Wu R, Joachimiak G, Mazmanian SK, Missiakas DM, Gornicki P, Schneewind O, Joachimiak A Structure. 2004 Jul;12(7):1147-56. PMID:15242591<ref>PMID:15242591</ref>

-	~~===1.6A crystal structure~~ of the ~~protein BA4783/Q81L49 (similar to sortase B) from Bacillus anthracis~~.~~===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_15242591}}~~	+	== References ==
-		+	<references/>
-	~~==About this Structure==~~	+	__TOC__
-	~~[[1rz2]] is a 1 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org~~/~~wiki/Bacillus_anthracis Bacillus anthracis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1RZ2 OCA].~~	+	</StructureSection>
-		+
-	==~~Reference~~==	+
-	<~~ref group="xtra">PMID:015242591<~~/~~ref~~><~~references group="xtra"~~/>	+
	[[Category: Bacillus anthracis]]		[[Category: Bacillus anthracis]]
	[[Category: Gornicki, P.]]		[[Category: Gornicki, P.]]

OCA: Protected "1rz2" [edit=sysop:move=sysop]

OCA — Fri, 04 Jan 2013 10:52:57 GMT

Protected "1rz2" [edit=sysop:move=sysop]

←Older revision

Revision as of 10:52, 4 January 2013

OCA at 10:52, 4 January 2013

OCA — Fri, 04 Jan 2013 10:52:55 GMT

←Older revision		Revision as of 10:52, 4 January 2013
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-	{{Seed}}
	[[Image:1rz2.png\|left\|200px]]		[[Image:1rz2.png\|left\|200px]]

-	<!--
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	{{STRUCTURE_1rz2\| PDB=1rz2 \| SCENE= }}		{{STRUCTURE_1rz2\| PDB=1rz2 \| SCENE= }}

	===1.6A crystal structure of the protein BA4783/Q81L49 (similar to sortase B) from Bacillus anthracis.===		===1.6A crystal structure of the protein BA4783/Q81L49 (similar to sortase B) from Bacillus anthracis.===

-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_15242591}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where 15242591 is the PubMed ID number.
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	{{ABSTRACT_PUBMED_15242591}}		{{ABSTRACT_PUBMED_15242591}}

	==About this Structure==		==About this Structure==
-	~~1RZ2~~ is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/~~Bacillus_anthracis_str._ames~~ Bacillus anthracis ~~str. ames~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1RZ2 OCA].	+	[[1rz2]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacillus_anthracis Bacillus anthracis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1RZ2 OCA].

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~15242591~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:015242591</ref><references group="xtra"/>
-	[[Category: Bacillus anthracis ~~str. ames~~]]	+	[[Category: Bacillus anthracis]]
	[[Category: Gornicki, P.]]		[[Category: Gornicki, P.]]
	[[Category: Joachimiak, A.]]		[[Category: Joachimiak, A.]]
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	[[Category: Sortase b protein]]		[[Category: Sortase b protein]]
	[[Category: Structural genomic]]		[[Category: Structural genomic]]
-		+	[[Category: Unknown function]]
-	~~''Page seeded by~~ [~~http~~:~~//oca.weizmann.ac.il/oca OCA~~ ] ~~on Tue Feb 17 03:14:53 2009''~~	+

OCA at 01:14, 17 February 2009

OCA — Tue, 17 Feb 2009 01:14:56 GMT

←Older revision		Revision as of 01:14, 17 February 2009
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	==Reference==		==Reference==
-	Structures of sortase B from Staphylococcus aureus and Bacillus anthracis reveal catalytic amino acid triad in the active site., Zhang R, Wu R, Joachimiak G, Mazmanian SK, Missiakas DM, Gornicki P, Schneewind O, Joachimiak A, Structure. 2004 Jul;12(7):1147-56. PMID:~~[http:~~//~~www.ncbi.nlm.nih.gov/pubmed/15242591 15242591]~~	+	<ref group="xtra">PMID:15242591</ref><references group="xtra"/>
	[[Category: Bacillus anthracis str. ames]]		[[Category: Bacillus anthracis str. ames]]
	[[Category: Gornicki, P.]]		[[Category: Gornicki, P.]]
Line 38:		Line 38:
	[[Category: Structural genomic]]		[[Category: Structural genomic]]

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on ~~Sun Nov 16~~ 17:51:~~07 2008~~''	+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 03:14:53 2009''