1tj3 - Revision history

OCA at 06:30, 23 August 2023

OCA — Wed, 23 Aug 2023 06:30:41 GMT

←Older revision		Revision as of 06:30, 23 August 2023
Line 3:		Line 3:
	<StructureSection load='1tj3' size='340' side='right'caption='[[1tj3]], [[Resolution\|resolution]] 2.80Å' scene=''>		<StructureSection load='1tj3' size='340' side='right'caption='[[1tj3]], [[Resolution\|resolution]] 2.80Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1tj3]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Aphanocapsa_sp~~.~~_(strain_n-1) Aphanocapsa~~ sp. ~~(strain n-1)~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1TJ3 OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=1TJ3 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1tj3]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Synechocystis_sp._PCC_6803 Synechocystis sp. PCC 6803]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1TJ3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1TJ3 FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>~~	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.8Å</td></tr>
-	~~<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max~~-~~height: 3em;'>[[1tj4\|1tj4]]~~, [[~~1tj5~~\|~~1tj5~~]]~~</div>~~</td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
-	<tr id='~~gene~~'><td class="sblockLbl"><b>[[~~Gene~~\|~~Gene~~:]]</b></td><td class="sblockDat"~~>SPP ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&~~id=~~1148 Aphanocapsa sp. (strain N-1)])</td~~><~~/tr>~~	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1tj3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1tj3 OCA], [https://pdbe.org/1tj3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1tj3 RCSB], [https://www.ebi.ac.uk/pdbsum/1tj3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1tj3 ProSAT]</span></td></tr>
-	~~<tr id~~='~~activity'><td class~~=~~"sblockLbl"><b>Activity~~:~~</b></td><td class="sblockDat"><span class='plainlinks~~'>~~[http://en.wikipedia.org/wiki/Sucrose-phosphate_phosphatase Sucrose-phosphate phosphatase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.3.24 3.1.3.24]~~ </~~span~~></td></tr>	+
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=1tj3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1tj3 OCA], [~~http~~://pdbe.org/1tj3 PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=1tj3 RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/1tj3 PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=1tj3 ProSAT]</span></td></tr>	+
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/P74325_SYNY3 P74325_SYNY3]
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 34:		Line 34:
	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: ~~Sucrose-phosphate phosphatase~~]]	+	[[Category: Synechocystis sp. PCC 6803]]
-	[[Category: Borel, F]]	+	[[Category: Borel F]]
-	[[Category: Ferrer, J L]]	+	[[Category: Ferrer J-L]]
-	[[Category: Fieulaine, S]]	+	[[Category: Fieulaine S]]
-	[[Category: Lunn~~, J E]]~~	+	[[Category: Lunn JE]]
-	~~[[Category: Cyanobacteria]]~~	+
-	~~[[Category: Had superfamily]]~~	+
-	~~[[Category: Hydrolase]]~~	+
-	~~[[Category: Phosphoydrolase]]~~	+
-	~~[[Category: Sucrose~~]]	+

OCA at 11:52, 24 December 2020

OCA — Thu, 24 Dec 2020 11:52:58 GMT

←Older revision		Revision as of 11:52, 24 December 2020
Line 1:		Line 1:

	==X-Ray structure of the Sucrose-Phosphatase (SPP) from Synechocystis sp. PCC6803 in a closed conformation==		==X-Ray structure of the Sucrose-Phosphatase (SPP) from Synechocystis sp. PCC6803 in a closed conformation==
-	<StructureSection load='1tj3' size='340' side='right' caption='[[1tj3]], [[Resolution\|resolution]] 2.80Å' scene=''>	+	<StructureSection load='1tj3' size='340' side='right'caption='[[1tj3]], [[Resolution\|resolution]] 2.80Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1tj3]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Aphanocapsa_sp._(strain_n-1) Aphanocapsa sp. (strain n-1)]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1TJ3 OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1TJ3 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1tj3]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Aphanocapsa_sp._(strain_n-1) Aphanocapsa sp. (strain n-1)]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1TJ3 OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=1TJ3 FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1tj4\|1tj4]], [[1tj5\|1tj5]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1tj4\|1tj4]], [[1tj5\|1tj5]]</div></td></tr>
	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">SPP ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1148 Aphanocapsa sp. (strain N-1)])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">SPP ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1148 Aphanocapsa sp. (strain N-1)])</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Sucrose-phosphate_phosphatase Sucrose-phosphate phosphatase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.3.24 3.1.3.24] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Sucrose-phosphate_phosphatase Sucrose-phosphate phosphatase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.3.24 3.1.3.24] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1tj3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1tj3 OCA], [http://pdbe.org/1tj3 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1tj3 RCSB], [http://www.ebi.ac.uk/pdbsum/1tj3 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1tj3 ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=1tj3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1tj3 OCA], [http://pdbe.org/1tj3 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1tj3 RCSB], [http://www.ebi.ac.uk/pdbsum/1tj3 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1tj3 ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 33:		Line 33:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Large Structures]]
	[[Category: Sucrose-phosphate phosphatase]]		[[Category: Sucrose-phosphate phosphatase]]
	[[Category: Borel, F]]		[[Category: Borel, F]]

OCA at 08:41, 21 March 2018

OCA — Wed, 21 Mar 2018 08:41:07 GMT

←Older revision		Revision as of 08:41, 21 March 2018
Line 1:		Line 1:
		+
	==X-Ray structure of the Sucrose-Phosphatase (SPP) from Synechocystis sp. PCC6803 in a closed conformation==		==X-Ray structure of the Sucrose-Phosphatase (SPP) from Synechocystis sp. PCC6803 in a closed conformation==
	<StructureSection load='1tj3' size='340' side='right' caption='[[1tj3]], [[Resolution\|resolution]] 2.80Å' scene=''>		<StructureSection load='1tj3' size='340' side='right' caption='[[1tj3]], [[Resolution\|resolution]] 2.80Å' scene=''>
Line 7:		Line 8:
	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">SPP ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1148 Aphanocapsa sp. (strain N-1)])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">SPP ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1148 Aphanocapsa sp. (strain N-1)])</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Sucrose-phosphate_phosphatase Sucrose-phosphate phosphatase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.3.24 3.1.3.24] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Sucrose-phosphate_phosphatase Sucrose-phosphate phosphatase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.3.24 3.1.3.24] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1tj3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1tj3 OCA], [http://pdbe.org/1tj3 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1tj3 RCSB], [http://www.ebi.ac.uk/pdbsum/1tj3 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1tj3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1tj3 OCA], [http://pdbe.org/1tj3 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1tj3 RCSB], [http://www.ebi.ac.uk/pdbsum/1tj3 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1tj3 ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 13:		Line 14:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/tj/1tj3_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/tj/1tj3_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1tj3 ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 00:42, 12 September 2015

OCA — Sat, 12 Sep 2015 00:42:06 GMT

←Older revision		Revision as of 00:42, 12 September 2015
Line 2:		Line 2:
	<StructureSection load='1tj3' size='340' side='right' caption='[[1tj3]], [[Resolution\|resolution]] 2.80Å' scene=''>		<StructureSection load='1tj3' size='340' side='right' caption='[[1tj3]], [[Resolution\|resolution]] 2.80Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1tj3]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Synechocystis_sp~~.~~_pcc_6803 Synechocystis~~ sp. ~~pcc 6803~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1TJ3 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1TJ3 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1tj3]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Aphanocapsa_sp._(strain_n-1) Aphanocapsa sp. (strain n-1)]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1TJ3 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1TJ3 FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1tj4\|1tj4]], [[1tj5\|1tj5]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1tj4\|1tj4]], [[1tj5\|1tj5]]</td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">SPP ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1148 ~~Synechocystis~~ sp. ~~PCC 6803~~])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">SPP ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1148 Aphanocapsa sp. (strain N-1)])</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Sucrose-phosphate_phosphatase Sucrose-phosphate phosphatase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.3.24 3.1.3.24] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Sucrose-phosphate_phosphatase Sucrose-phosphate phosphatase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.3.24 3.1.3.24] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1tj3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1tj3 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1tj3 RCSB], [http://www.ebi.ac.uk/pdbsum/1tj3 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1tj3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1tj3 OCA], [http://pdbe.org/1tj3 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1tj3 RCSB], [http://www.ebi.ac.uk/pdbsum/1tj3 PDBsum]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 27:		Line 27:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 1tj3" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>
Line 32:		Line 33:
	</StructureSection>		</StructureSection>
	[[Category: Sucrose-phosphate phosphatase]]		[[Category: Sucrose-phosphate phosphatase]]
-	[[Category: Synechocystis sp. pcc 6803]]
	[[Category: Borel, F]]		[[Category: Borel, F]]
	[[Category: Ferrer, J L]]		[[Category: Ferrer, J L]]

OCA at 08:02, 6 January 2015

OCA — Tue, 06 Jan 2015 08:02:05 GMT

←Older revision		Revision as of 08:02, 6 January 2015
Line 1:		Line 1:
-	[[~~Image:~~1tj3.~~png~~\|~~left~~\|200px]]	+	==X-Ray structure of the Sucrose-Phosphatase (SPP) from Synechocystis sp. PCC6803 in a closed conformation==
		+	<StructureSection load='1tj3' size='340' side='right' caption='[[1tj3]], [[Resolution\|resolution]] 2.80Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[1tj3]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Synechocystis_sp._pcc_6803 Synechocystis sp. pcc 6803]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1TJ3 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1TJ3 FirstGlance]. <br>
		+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
		+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1tj4\|1tj4]], [[1tj5\|1tj5]]</td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">SPP ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1148 Synechocystis sp. PCC 6803])</td></tr>
		+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Sucrose-phosphate_phosphatase Sucrose-phosphate phosphatase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.3.24 3.1.3.24] </span></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1tj3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1tj3 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1tj3 RCSB], [http://www.ebi.ac.uk/pdbsum/1tj3 PDBsum]</span></td></tr>
		+	</table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/tj/1tj3_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Sucrose-phosphatase (SPP) catalyzes the final step in the pathway of sucrose biosynthesis in both plants and cyanobacteria, and the SPPs from these two groups of organisms are closely related. We have crystallized the enzyme from the cyanobacterium Synechocystis sp PCC 6803 and determined its crystal structure alone and in complex with various ligands. The protein consists of a core domain containing the catalytic site and a smaller cap domain that contains a glucose binding site. Two flexible hinge loops link the two domains, forming a structure that resembles a pair of sugar tongs. The glucose binding site plays a major role in determining the enzyme's remarkable substrate specificity and is also important for its inhibition by sucrose and glucose. It is proposed that the catalytic reaction is initiated by nucleophilic attack on the substrate by Asp9 and involves formation of a covalent phospho-Asp9-enzyme intermediate. From modeling based on the SPP structure, we predict that the noncatalytic SPP-like domain of the Synechocystis sucrose-phosphate synthase could bind sucrose-6(F)-phosphate and propose that this domain might be involved in metabolite channeling between the last two enzymes in the pathway of sucrose synthesis.

-	~~{{STRUCTURE_1tj3\| PDB=1tj3 \| SCENE= }}~~	+	The structure of a cyanobacterial sucrose-phosphatase reveals the sugar tongs that release free sucrose in the cell.,Fieulaine S, Lunn JE, Borel F, Ferrer JL Plant Cell. 2005 Jul;17(7):2049-58. Epub 2005 Jun 3. PMID:15937230<ref>PMID:15937230</ref>

-	~~===X-Ray structure~~ of the ~~Sucrose-Phosphatase (SPP) from Synechocystis sp~~. ~~PCC6803 in a closed conformation===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_15937230}}~~	+	== References ==
-		+	<references/>
-	~~==About this Structure==~~	+	__TOC__
-	~~[[1tj3]] is a 1 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org~~/~~wiki/Synechocystis_sp._pcc_6803 Synechocystis sp. pcc 6803]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1TJ3 OCA].~~	+	</StructureSection>
-		+
-	==~~Reference~~==	+
-	<~~ref group="xtra">PMID:015937230<~~/~~ref~~><~~references group="xtra"~~/>	+
	[[Category: Sucrose-phosphate phosphatase]]		[[Category: Sucrose-phosphate phosphatase]]
	[[Category: Synechocystis sp. pcc 6803]]		[[Category: Synechocystis sp. pcc 6803]]
-	[[Category: Borel, F.]]	+	[[Category: Borel, F]]
-	[[Category: Ferrer, J L.]]	+	[[Category: Ferrer, J L]]
-	[[Category: Fieulaine, S.]]	+	[[Category: Fieulaine, S]]
-	[[Category: Lunn, J E.]]	+	[[Category: Lunn, J E]]
	[[Category: Cyanobacteria]]		[[Category: Cyanobacteria]]
	[[Category: Had superfamily]]		[[Category: Had superfamily]]

OCA: Protected "1tj3" [edit=sysop:move=sysop]

OCA — Sat, 05 Jan 2013 11:54:21 GMT

Protected "1tj3" [edit=sysop:move=sysop]

←Older revision

Revision as of 11:54, 5 January 2013

OCA at 11:54, 5 January 2013

OCA — Sat, 05 Jan 2013 11:54:19 GMT

←Older revision		Revision as of 11:54, 5 January 2013
Line 1:		Line 1:
-	{{Seed}}
	[[Image:1tj3.png\|left\|200px]]		[[Image:1tj3.png\|left\|200px]]

-	<!--
-	The line below this paragraph, containing "STRUCTURE_1tj3", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_1tj3\| PDB=1tj3 \| SCENE= }}		{{STRUCTURE_1tj3\| PDB=1tj3 \| SCENE= }}

	===X-Ray structure of the Sucrose-Phosphatase (SPP) from Synechocystis sp. PCC6803 in a closed conformation===		===X-Ray structure of the Sucrose-Phosphatase (SPP) from Synechocystis sp. PCC6803 in a closed conformation===

-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_15937230}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where 15937230 is the PubMed ID number.
-	-->
	{{ABSTRACT_PUBMED_15937230}}		{{ABSTRACT_PUBMED_15937230}}

	==About this Structure==		==About this Structure==
-	~~1TJ3~~ is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Synechocystis_sp. Synechocystis sp.]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1TJ3 OCA].	+	[[1tj3]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Synechocystis_sp._pcc_6803 Synechocystis sp. pcc 6803]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1TJ3 OCA].

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~15937230~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:015937230</ref><references group="xtra"/>
-	[[Category: Sucrose-phosphatase]]	+	[[Category: Sucrose-phosphate phosphatase]]
-	[[Category: Synechocystis sp.]]	+	[[Category: Synechocystis sp. pcc 6803]]
	[[Category: Borel, F.]]		[[Category: Borel, F.]]
	[[Category: Ferrer, J L.]]		[[Category: Ferrer, J L.]]
Line 32:		Line 20:
	[[Category: Cyanobacteria]]		[[Category: Cyanobacteria]]
	[[Category: Had superfamily]]		[[Category: Had superfamily]]
		+	[[Category: Hydrolase]]
	[[Category: Phosphoydrolase]]		[[Category: Phosphoydrolase]]
	[[Category: Sucrose]]		[[Category: Sucrose]]
-
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 18 08:26:35 2009''

OCA at 06:26, 18 February 2009

OCA — Wed, 18 Feb 2009 06:26:36 GMT

←Older revision		Revision as of 06:26, 18 February 2009
Line 20:		Line 20:

	==About this Structure==		==About this Structure==
-	1TJ3 is a ~~[[Single protein]]~~ structure of sequence from [http://en.wikipedia.org/wiki/Synechocystis_sp. Synechocystis sp.]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1TJ3 OCA].	+	1TJ3 is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Synechocystis_sp. Synechocystis sp.]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1TJ3 OCA].

	==Reference==		==Reference==
-	The structure of a cyanobacterial sucrose-phosphatase reveals the sugar tongs that release free sucrose in the cell., Fieulaine S, Lunn JE, Borel F, Ferrer JL, Plant Cell. 2005 Jul;17(7):2049-58. Epub 2005 Jun 3. PMID:~~[http:~~//~~www.ncbi.nlm.nih.gov/pubmed/15937230 15937230]~~	+	<ref group="xtra">PMID:15937230</ref><references group="xtra"/>
-	~~[[Category: Single protein]]~~	+
	[[Category: Sucrose-phosphatase]]		[[Category: Sucrose-phosphatase]]
	[[Category: Synechocystis sp.]]		[[Category: Synechocystis sp.]]
Line 36:		Line 35:
	[[Category: Sucrose]]		[[Category: Sucrose]]

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on ~~Tue Jul 29 14~~:44:~~37 2008~~''	+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 18 08:26:35 2009''

OCA at 11:44, 29 July 2008

OCA — Tue, 29 Jul 2008 11:44:41 GMT

←Older revision		Revision as of 11:44, 29 July 2008
Line 1:		Line 1:
-	[[Image:1tj3.~~gif~~\|left\|200px]]	+	{{Seed}}
		+	[[Image:1tj3.png\|left\|200px]]

	<!--		<!--
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	{{STRUCTURE_1tj3\| PDB=1tj3 \| SCENE= }}		{{STRUCTURE_1tj3\| PDB=1tj3 \| SCENE= }}

-	~~'''~~X-Ray structure of the Sucrose-Phosphatase (SPP) from Synechocystis sp. PCC6803 in a closed conformation~~'''~~	+	===X-Ray structure of the Sucrose-Phosphatase (SPP) from Synechocystis sp. PCC6803 in a closed conformation===


-	~~==Overview==~~	+	<!--
-	~~Sucrose-phosphatase (SPP) catalyzes the final step in the pathway of sucrose biosynthesis in both plants and cyanobacteria~~, ~~and~~ the ~~SPPs from these two groups of organisms are closely related. We have crystallized~~ the ~~enzyme from the cyanobacterium Synechocystis sp PCC 6803 and determined its crystal structure alone and in complex with various ligands~~. ~~The protein consists of a core domain containing the catalytic site and a smaller cap domain that contains a glucose binding site~~. ~~Two flexible hinge loops link the two domains~~, forming a structure that resembles a pair of sugar tongs. The glucose binding site plays a major role in determining the enzyme's remarkable substrate specificity and is also important for its inhibition by sucrose and glucose. It is ~~proposed that~~ the ~~catalytic reaction is initiated by nucleophilic attack on the substrate by Asp9 and involves formation of a covalent phospho-Asp9-enzyme intermediate~~. ~~From modeling based on the SPP structure, we predict that the noncatalytic SPP~~-~~like domain of the Synechocystis sucrose~~-~~phosphate synthase could bind sucrose-6(F)-phosphate and propose that this domain might be involved in metabolite channeling between the last two enzymes in the pathway of sucrose synthesis.~~	+	The line below this paragraph, {{ABSTRACT_PUBMED_15937230}}, adds the Publication Abstract to the page
		+	(as it appears on PubMed at http://www.pubmed.gov), where 15937230 is the PubMed ID number.
		+	-->
		+	{{ABSTRACT_PUBMED_15937230}}

	==About this Structure==		==About this Structure==
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	[[Category: Phosphoydrolase]]		[[Category: Phosphoydrolase]]
	[[Category: Sucrose]]		[[Category: Sucrose]]
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on ~~Sat May 3 10~~:00:31 2008''	+
		+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 29 14:44:37 2008''

OCA at 07:00, 3 May 2008

OCA — Sat, 03 May 2008 07:00:32 GMT

←Older revision		Revision as of 07:00, 3 May 2008
Line 1:		Line 1:
	[[Image:1tj3.gif\|left\|200px]]		[[Image:1tj3.gif\|left\|200px]]

-	~~{{Structure~~	+	<!--
-	~~\|PDB= 1tj3 \|SIZE=350\|CAPTION=~~ <~~scene name='initialview01'>1tj3</scene>, resolution 2.80Å~~	+	The line below this paragraph, containing "STRUCTURE_1tj3", creates the "Structure Box" on the page.
-	~~\|SITE=~~	+	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	~~\|LIGAND= <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>~~	+	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	~~\|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Sucrose~~-~~phosphatase Sucrose~~-~~phosphatase]~~, ~~with EC number [http://www~~.~~brenda-enzymes.info/php/result_flat.php4?ecno=3.1.3.24 3.1.3.24] </span>~~	+	or leave the SCENE parameter empty for the default display.
-	~~\|GENE= SPP~~ (~~[http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1143 Synechocystis sp.]~~)	+	-->
-	~~\|DOMAIN=~~	+	{{STRUCTURE_1tj3\| PDB=1tj3 \| SCENE= }}
-	~~\|RELATEDENTRY=[[1tj4\|1TJ4]]~~, ~~[[1tj5\|1TJ5]]~~	+
-	~~\|RESOURCES=<span class='plainlinks'>[http://oca~~.~~weizmann.ac.il/oca~~-~~docs/fgij/fg.htm?mol=1tj3 FirstGlance], [http://oca.weizmann.ac.il/oca~~-~~bin/ocaids?id~~=1tj3 ~~OCA], [http://www.ebi.ac.uk/pdbsum/1tj3 PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId~~=~~1tj3 RCSB]</span>~~	+
-	}}	+

	'''X-Ray structure of the Sucrose-Phosphatase (SPP) from Synechocystis sp. PCC6803 in a closed conformation'''		'''X-Ray structure of the Sucrose-Phosphatase (SPP) from Synechocystis sp. PCC6803 in a closed conformation'''
Line 30:		Line 27:
	[[Category: Fieulaine, S.]]		[[Category: Fieulaine, S.]]
	[[Category: Lunn, J E.]]		[[Category: Lunn, J E.]]
-	[[Category: ~~cyanobacteria~~]]	+	[[Category: Cyanobacteria]]
-	[[Category: ~~had~~ superfamily]]	+	[[Category: Had superfamily]]
-	[[Category: ~~phosphoydrolase~~]]	+	[[Category: Phosphoydrolase]]
-	[[Category: ~~sucrose~~]]	+	[[Category: Sucrose]]
-		+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 10:00:31 2008''
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on ~~Sun Mar 30 23~~:56:46 2008''	+