1u0b - Revision history

OCA at 06:35, 23 August 2023

OCA — Wed, 23 Aug 2023 06:35:54 GMT

←Older revision		Revision as of 06:35, 23 August 2023
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	<StructureSection load='1u0b' size='340' side='right'caption='[[1u0b]], [[Resolution\|resolution]] 2.30Å' scene=''>		<StructureSection load='1u0b' size='340' side='right'caption='[[1u0b]], [[Resolution\|resolution]] 2.30Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1u0b]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1U0B OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1U0B FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1u0b]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli] and [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1U0B OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1U0B FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=ZN:ZINC+ION'>ZN</scene>~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.3Å</td></tr>
-	<tr id='~~activity~~'><td class="sblockLbl"><b>~~Activity~~:</b></td><td class="sblockDat"><~~span class~~='~~plainlinks~~'>~~[https://en.wikipedia.org/wiki/Cysteine--tRNA_ligase Cysteine--tRNA ligase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=6.1.1.16 6.1.1.16]~~ </~~span~~></td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1u0b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1u0b OCA], [https://pdbe.org/1u0b PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1u0b RCSB], [https://www.ebi.ac.uk/pdbsum/1u0b PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1u0b ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1u0b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1u0b OCA], [https://pdbe.org/1u0b PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1u0b RCSB], [https://www.ebi.ac.uk/pdbsum/1u0b PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1u0b ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/SYC_ECOLI SYC_ECOLI]
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Cysteine~~-~~-tRNA ligase~~]]	+	[[Category: Escherichia coli]]
		+	[[Category: Escherichia coli K-12]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Hauenstein, S]]	+	[[Category: Hauenstein S]]
-	[[Category: Hou~~, Y M~~]]	+	[[Category: Hou YM]]
-	[[Category: Perona~~, J J~~]]	+	[[Category: Perona JJ]]
-	[[Category: Zhang~~, C M]]~~	+	[[Category: Zhang CM]]
-	~~[[Category: Ligase-rna complex]]~~	+
-	~~[[Category: Protein-rna complex~~]]	+

OCA at 09:35, 29 September 2021

OCA — Wed, 29 Sep 2021 09:35:01 GMT

←Older revision		Revision as of 09:35, 29 September 2021
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	<StructureSection load='1u0b' size='340' side='right'caption='[[1u0b]], [[Resolution\|resolution]] 2.30Å' scene=''>		<StructureSection load='1u0b' size='340' side='right'caption='[[1u0b]], [[Resolution\|resolution]] 2.30Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1u0b]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1U0B OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1U0B FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1u0b]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1U0B OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1U0B FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://en.wikipedia.org/wiki/Cysteine--tRNA_ligase Cysteine--tRNA ligase], with EC number [~~http~~://www.brenda-enzymes.info/php/result_flat.php4?ecno=6.1.1.16 6.1.1.16] </span></td></tr>	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Cysteine--tRNA_ligase Cysteine--tRNA ligase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=6.1.1.16 6.1.1.16] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1u0b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1u0b OCA], [~~http~~://pdbe.org/1u0b PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=1u0b RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/1u0b PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=1u0b ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1u0b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1u0b OCA], [https://pdbe.org/1u0b PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1u0b RCSB], [https://www.ebi.ac.uk/pdbsum/1u0b PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1u0b ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==

OCA at 13:42, 25 December 2019

OCA — Wed, 25 Dec 2019 13:42:11 GMT

←Older revision		Revision as of 13:42, 25 December 2019
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	==Crystal structure of cysteinyl-tRNA synthetase binary complex with tRNACys==		==Crystal structure of cysteinyl-tRNA synthetase binary complex with tRNACys==
-	<StructureSection load='1u0b' size='340' side='right' caption='[[1u0b]], [[Resolution\|resolution]] 2.30Å' scene=''>	+	<StructureSection load='1u0b' size='340' side='right'caption='[[1u0b]], [[Resolution\|resolution]] 2.30Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1u0b]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1U0B OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1U0B FirstGlance]. <br>		<table><tr><td colspan='2'>[[1u0b]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1U0B OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1U0B FirstGlance]. <br>
Line 29:		Line 29:

	==See Also==		==See Also==
-	*[[Aminoacyl tRNA ~~Synthetase~~\|Aminoacyl tRNA ~~Synthetase~~]]	+	*[[Aminoacyl tRNA synthetase 3D structures\|Aminoacyl tRNA synthetase 3D structures]]
-	*[[~~TRNA~~\|~~TRNA~~]]	+	*[[Transfer RNA (tRNA)\|Transfer RNA (tRNA)]]
	== References ==		== References ==
	<references/>		<references/>
Line 36:		Line 36:
	</StructureSection>		</StructureSection>
	[[Category: Cysteine--tRNA ligase]]		[[Category: Cysteine--tRNA ligase]]
		+	[[Category: Large Structures]]
	[[Category: Hauenstein, S]]		[[Category: Hauenstein, S]]
	[[Category: Hou, Y M]]		[[Category: Hou, Y M]]

OCA at 08:32, 21 March 2018

OCA — Wed, 21 Mar 2018 08:32:45 GMT

←Older revision		Revision as of 08:32, 21 March 2018
Line 1:		Line 1:
		+
	==Crystal structure of cysteinyl-tRNA synthetase binary complex with tRNACys==		==Crystal structure of cysteinyl-tRNA synthetase binary complex with tRNACys==
	<StructureSection load='1u0b' size='340' side='right' caption='[[1u0b]], [[Resolution\|resolution]] 2.30Å' scene=''>		<StructureSection load='1u0b' size='340' side='right' caption='[[1u0b]], [[Resolution\|resolution]] 2.30Å' scene=''>
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	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Cysteine--tRNA_ligase Cysteine--tRNA ligase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=6.1.1.16 6.1.1.16] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Cysteine--tRNA_ligase Cysteine--tRNA ligase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=6.1.1.16 6.1.1.16] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1u0b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1u0b OCA], [http://pdbe.org/1u0b PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1u0b RCSB], [http://www.ebi.ac.uk/pdbsum/1u0b PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1u0b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1u0b OCA], [http://pdbe.org/1u0b PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1u0b RCSB], [http://www.ebi.ac.uk/pdbsum/1u0b PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1u0b ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 11:		Line 12:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/u0/1u0b_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/u0/1u0b_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1u0b ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
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	==See Also==		==See Also==
	*[[Aminoacyl tRNA Synthetase\|Aminoacyl tRNA Synthetase]]		*[[Aminoacyl tRNA Synthetase\|Aminoacyl tRNA Synthetase]]
		+	*[[TRNA\|TRNA]]
	== References ==		== References ==
	<references/>		<references/>

OCA at 13:38, 11 September 2015

OCA — Fri, 11 Sep 2015 13:38:32 GMT

←Older revision		Revision as of 13:38, 11 September 2015
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	<StructureSection load='1u0b' size='340' side='right' caption='[[1u0b]], [[Resolution\|resolution]] 2.30Å' scene=''>		<StructureSection load='1u0b' size='340' side='right' caption='[[1u0b]], [[Resolution\|resolution]] 2.30Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1u0b]] is a 2 chain structure ~~with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]~~. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1U0B OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1U0B FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1u0b]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1U0B OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1U0B FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">cysS ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 Escherichia coli])</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Cysteine--tRNA_ligase Cysteine--tRNA ligase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=6.1.1.16 6.1.1.16] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Cysteine--tRNA_ligase Cysteine--tRNA ligase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=6.1.1.16 6.1.1.16] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1u0b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1u0b OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1u0b RCSB], [http://www.ebi.ac.uk/pdbsum/1u0b PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1u0b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1u0b OCA], [http://pdbe.org/1u0b PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1u0b RCSB], [http://www.ebi.ac.uk/pdbsum/1u0b PDBsum]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
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	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 1u0b" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
Line 34:		Line 34:
	</StructureSection>		</StructureSection>
	[[Category: Cysteine--tRNA ligase]]		[[Category: Cysteine--tRNA ligase]]
-	[[Category: Escherichia coli]]
	[[Category: Hauenstein, S]]		[[Category: Hauenstein, S]]
	[[Category: Hou, Y M]]		[[Category: Hou, Y M]]

OCA at 12:30, 6 January 2015

OCA — Tue, 06 Jan 2015 12:30:07 GMT

←Older revision		Revision as of 12:30, 6 January 2015
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1u0b]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1U0B OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1U0B FirstGlance]. <br>		<table><tr><td colspan='2'>[[1u0b]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1U0B OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1U0B FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene><br>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
-	<tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">cysS ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 Escherichia coli])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">cysS ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 Escherichia coli])</td></tr>
-	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Cysteine--tRNA_ligase Cysteine--tRNA ligase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=6.1.1.16 6.1.1.16] </span></td></tr>	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Cysteine--tRNA_ligase Cysteine--tRNA ligase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=6.1.1.16 6.1.1.16] </span></td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1u0b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1u0b OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1u0b RCSB], [http://www.ebi.ac.uk/pdbsum/1u0b PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1u0b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1u0b OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1u0b RCSB], [http://www.ebi.ac.uk/pdbsum/1u0b PDBsum]</span></td></tr>
-	<table>	+	</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 35:		Line 35:
	[[Category: Cysteine--tRNA ligase]]		[[Category: Cysteine--tRNA ligase]]
	[[Category: Escherichia coli]]		[[Category: Escherichia coli]]
-	[[Category: Hauenstein, S.]]	+	[[Category: Hauenstein, S]]
-	[[Category: Hou, Y M.]]	+	[[Category: Hou, Y M]]
-	[[Category: Perona, J J.]]	+	[[Category: Perona, J J]]
-	[[Category: Zhang, C M.]]	+	[[Category: Zhang, C M]]
	[[Category: Ligase-rna complex]]		[[Category: Ligase-rna complex]]
	[[Category: Protein-rna complex]]		[[Category: Protein-rna complex]]

OCA at 22:17, 28 September 2014

OCA — Sun, 28 Sep 2014 22:17:23 GMT

←Older revision		Revision as of 22:17, 28 September 2014
Line 1:		Line 1:
-	[[~~Image:~~1u0b.~~png~~\|~~left~~\|200px]]	+	==Crystal structure of cysteinyl-tRNA synthetase binary complex with tRNACys==
		+	<StructureSection load='1u0b' size='340' side='right' caption='[[1u0b]], [[Resolution\|resolution]] 2.30Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[1u0b]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1U0B OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1U0B FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene><br>
		+	<tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">cysS ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 Escherichia coli])</td></tr>
		+	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Cysteine--tRNA_ligase Cysteine--tRNA ligase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=6.1.1.16 6.1.1.16] </span></td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1u0b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1u0b OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1u0b RCSB], [http://www.ebi.ac.uk/pdbsum/1u0b PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/u0/1u0b_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	The crystal structure of Escherichia coli cysteinyl-tRNA synthetase (CysRS) bound to tRNA(Cys) at a resolution of 2.3 A reveals base-specific and shape-selective interactions across an extensive protein-RNA recognition interface. The complex contains a mixed alpha/beta C-terminal domain, which is disordered in the unliganded enzyme. This domain makes specific hydrogen bonding interactions with all three bases of the GCA anticodon. The tRNA anticodon stem is bent sharply toward the enzyme as compared with its conformation when bound to elongation factor Tu, providing an essential basis for shape-selective recognition. The CysRS structure also reveals interactions of conserved enzyme groups with the sugar-phosphate backbone in the D loop, adjacent to an unusual G15.G48 tertiary base pair previously implicated in tRNA aminoacylation. A combined mutational analysis of enzyme and tRNA groups at G15.G48 supports the notion that contacts between CysRS and the sugar-phosphate backbone contribute to recognition by indirect readout.

-	~~{{STRUCTURE_1u0b\| PDB=1u0b \| SCENE= }}~~	+	Shape-selective RNA recognition by cysteinyl-tRNA synthetase.,Hauenstein S, Zhang CM, Hou YM, Perona JJ Nat Struct Mol Biol. 2004 Nov;11(11):1134-41. Epub 2004 Oct 17. PMID:15489861<ref>PMID:15489861</ref>

-	~~===Crystal structure~~ of ~~cysteinyl-tRNA synthetase binary complex with tRNACys===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_15489861}}~~	+
-		+
-	~~==About this Structure==~~	+
-	~~[[1u0b]] is a 2 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Escherichia_coli Escherichia coli]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=1U0B OCA].~~	+

	==See Also==		==See Also==
	*[[Aminoacyl tRNA Synthetase\|Aminoacyl tRNA Synthetase]]		*[[Aminoacyl tRNA Synthetase\|Aminoacyl tRNA Synthetase]]
-		+	== References ==
-	==~~Reference~~==	+	<references/>
-	<~~ref group="xtra">PMID:015489861<~~/~~ref~~><~~ref group="xtra">PMID:019053270</ref><references group="xtra"~~/>	+	__TOC__
		+	</StructureSection>
	[[Category: Cysteine--tRNA ligase]]		[[Category: Cysteine--tRNA ligase]]
	[[Category: Escherichia coli]]		[[Category: Escherichia coli]]

OCA at 19:18, 20 October 2012

OCA — Sat, 20 Oct 2012 19:18:25 GMT

←Older revision		Revision as of 19:18, 20 October 2012
Line 8:		Line 8:

	==About this Structure==		==About this Structure==
-	[[1u0b]] is a 2 chain structure ~~of [[Aminoacyl tRNA Synthetase]]~~ with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1U0B OCA].	+	[[1u0b]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1U0B OCA].

	==See Also==		==See Also==

OCA: Protected "1u0b" [edit=sysop:move=sysop]

OCA — Fri, 27 Jul 2012 06:55:16 GMT

Protected "1u0b" [edit=sysop:move=sysop]

←Older revision

Revision as of 06:55, 27 July 2012

OCA at 06:55, 27 July 2012

OCA — Fri, 27 Jul 2012 06:55:12 GMT

←Older revision		Revision as of 06:55, 27 July 2012
Line 1:		Line 1:
-	{{Seed}}
	[[Image:1u0b.png\|left\|200px]]		[[Image:1u0b.png\|left\|200px]]

-	<!--
-	The line below this paragraph, containing "STRUCTURE_1u0b", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_1u0b\| PDB=1u0b \| SCENE= }}		{{STRUCTURE_1u0b\| PDB=1u0b \| SCENE= }}

	===Crystal structure of cysteinyl-tRNA synthetase binary complex with tRNACys===		===Crystal structure of cysteinyl-tRNA synthetase binary complex with tRNACys===

-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_15489861}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where 15489861 is the PubMed ID number.
-	-->
	{{ABSTRACT_PUBMED_15489861}}		{{ABSTRACT_PUBMED_15489861}}

	==About this Structure==		==About this Structure==
-	~~1U0B~~ is a 2 ~~chains~~ structure of ~~sequences~~ from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1U0B OCA].	+	[[1u0b]] is a 2 chain structure of [[Aminoacyl tRNA Synthetase]] with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1U0B OCA].
		+
		+	==See Also==
		+	*[[Aminoacyl tRNA Synthetase\|Aminoacyl tRNA Synthetase]]

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~15489861~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:015489861</ref><ref group="xtra">PMID:019053270</ref><references group="xtra"/>
	[[Category: Cysteine--tRNA ligase]]		[[Category: Cysteine--tRNA ligase]]
	[[Category: Escherichia coli]]		[[Category: Escherichia coli]]
Line 30:		Line 21:
	[[Category: Perona, J J.]]		[[Category: Perona, J J.]]
	[[Category: Zhang, C M.]]		[[Category: Zhang, C M.]]
		+	[[Category: Ligase-rna complex]]
	[[Category: Protein-rna complex]]		[[Category: Protein-rna complex]]
-
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 23:49:08 2009''