1u2l - Revision history

OCA at 06:37, 23 August 2023

OCA — Wed, 23 Aug 2023 06:37:19 GMT

←Older revision		Revision as of 06:37, 23 August 2023
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	<StructureSection load='1u2l' size='340' side='right'caption='[[1u2l]], [[Resolution\|resolution]] 2.30Å' scene=''>		<StructureSection load='1u2l' size='340' side='right'caption='[[1u2l]], [[Resolution\|resolution]] 2.30Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1u2l]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~"bacillus_coli"_migula_1895 "bacillus~~ coli~~" migula 1895~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1U2L OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=1U2L FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1u2l]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1U2L OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1U2L FirstGlance]. <br>
-	</td></tr><tr id='~~related~~'><td class="sblockLbl"><b>[[~~Related_structure~~\|~~Related~~:]]</b></td><td class="sblockDat"~~><div style='overflow: auto; max-height: 3em;'>[[1u2j\|1u2j]], [[1u2k\|1u2k]]</div></td></tr>~~	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.3Å</td></tr>
-	~~<tr~~ id~~='gene'><td class~~="~~sblockLbl~~">~~<b>~~[[~~Gene~~\|~~Gene:~~]]~~</b></td><td class="sblockDat">katG ([http://www~~.~~ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info~~&~~srchmode=5&id=562 "Bacillus coli" Migula 1895])</td></tr>~~	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1u2l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1u2l OCA], [https://pdbe.org/1u2l PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1u2l RCSB], [https://www.ebi.ac.uk/pdbsum/1u2l PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1u2l ProSAT]</span></td></tr>
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Catalase Catalase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.11.1.6 1.11.1.6] </span></td></tr>	+
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=1u2l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1u2l OCA], [~~http~~://pdbe.org/1u2l PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=1u2l RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/1u2l PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=1u2l ProSAT]</span></td></tr>	+
	</table>		</table>
	== Function ==		== Function ==
-	[~~[http~~://www.uniprot.org/uniprot/KATG_ECOLI KATG_ECOLI]] Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity. Displays also NADH oxidase, INH lyase and isonicotinoyl-NAD synthase activity.<ref>PMID:18178143</ref> <ref>PMID:23416055</ref> <ref>PMID:374409</ref>	+	[https://www.uniprot.org/uniprot/KATG_ECOLI KATG_ECOLI] Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity. Displays also NADH oxidase, INH lyase and isonicotinoyl-NAD synthase activity.<ref>PMID:18178143</ref> <ref>PMID:23416055</ref> <ref>PMID:374409</ref>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Bacillus~~ coli ~~migula 1895]]~~	+	[[Category: Escherichia coli]]
-	~~[[Category: Catalase~~]]	+
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Carpena, X]]	+	[[Category: Carpena X]]
-	[[Category: Fita, I]]	+	[[Category: Fita I]]
-	[[Category: Loewen~~, P C~~]]	+	[[Category: Loewen PC]]
-	[[Category: Melik-Adamyan, W]]	+	[[Category: Melik-Adamyan W]]
-	~~[[Category: C-terminal domain]]~~	+
-	~~[[Category: Catalase-peroxidase]]~~	+
-	~~[[Category: Katg]]~~	+
-	~~[[Category: Oxidoreductase~~]]	+

OCA at 07:19, 30 December 2020

OCA — Wed, 30 Dec 2020 07:19:24 GMT

←Older revision		Revision as of 07:19, 30 December 2020
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	==Crystal structure of the C-terminal domain from the catalase-peroxidase KatG of Escherichia coli (P1)==		==Crystal structure of the C-terminal domain from the catalase-peroxidase KatG of Escherichia coli (P1)==
-	<StructureSection load='1u2l' size='340' side='right' caption='[[1u2l]], [[Resolution\|resolution]] 2.30Å' scene=''>	+	<StructureSection load='1u2l' size='340' side='right'caption='[[1u2l]], [[Resolution\|resolution]] 2.30Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1u2l]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1U2L OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1U2L FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1u2l]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1U2L OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=1U2L FirstGlance]. <br>
-	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1u2j\|1u2j]], [[1u2k\|1u2k]]</td></tr>	+	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1u2j\|1u2j]], [[1u2k\|1u2k]]</div></td></tr>
	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">katG ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 "Bacillus coli" Migula 1895])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">katG ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 "Bacillus coli" Migula 1895])</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Catalase Catalase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.11.1.6 1.11.1.6] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Catalase Catalase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.11.1.6 1.11.1.6] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1u2l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1u2l OCA], [http://pdbe.org/1u2l PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1u2l RCSB], [http://www.ebi.ac.uk/pdbsum/1u2l PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1u2l ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=1u2l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1u2l OCA], [http://pdbe.org/1u2l PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1u2l RCSB], [http://www.ebi.ac.uk/pdbsum/1u2l PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1u2l ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 32:		Line 32:

	==See Also==		==See Also==
-	*[[Catalase\|Catalase]]	+	*[[Catalase 3D structures\|Catalase 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
Line 39:		Line 39:
	[[Category: Bacillus coli migula 1895]]		[[Category: Bacillus coli migula 1895]]
	[[Category: Catalase]]		[[Category: Catalase]]
		+	[[Category: Large Structures]]
	[[Category: Carpena, X]]		[[Category: Carpena, X]]
	[[Category: Fita, I]]		[[Category: Fita, I]]

OCA at 08:55, 21 March 2018

OCA — Wed, 21 Mar 2018 08:55:52 GMT

←Older revision		Revision as of 08:55, 21 March 2018
Line 1:		Line 1:
		+
	==Crystal structure of the C-terminal domain from the catalase-peroxidase KatG of Escherichia coli (P1)==		==Crystal structure of the C-terminal domain from the catalase-peroxidase KatG of Escherichia coli (P1)==
	<StructureSection load='1u2l' size='340' side='right' caption='[[1u2l]], [[Resolution\|resolution]] 2.30Å' scene=''>		<StructureSection load='1u2l' size='340' side='right' caption='[[1u2l]], [[Resolution\|resolution]] 2.30Å' scene=''>
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	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">katG ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 "Bacillus coli" Migula 1895])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">katG ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 "Bacillus coli" Migula 1895])</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Catalase Catalase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.11.1.6 1.11.1.6] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Catalase Catalase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.11.1.6 1.11.1.6] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1u2l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1u2l OCA], [http://pdbe.org/1u2l PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1u2l RCSB], [http://www.ebi.ac.uk/pdbsum/1u2l PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1u2l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1u2l OCA], [http://pdbe.org/1u2l PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1u2l RCSB], [http://www.ebi.ac.uk/pdbsum/1u2l PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1u2l ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 14:		Line 15:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/u2/1u2l_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/u2/1u2l_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>

OCA at 08:22, 8 February 2016

OCA — Mon, 08 Feb 2016 08:22:11 GMT

←Older revision		Revision as of 08:22, 8 February 2016
Line 18:		Line 18:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1u2l ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 09:40, 10 September 2015

OCA — Thu, 10 Sep 2015 09:40:04 GMT

←Older revision		Revision as of 09:40, 10 September 2015
Line 2:		Line 2:
	<StructureSection load='1u2l' size='340' side='right' caption='[[1u2l]], [[Resolution\|resolution]] 2.30Å' scene=''>		<StructureSection load='1u2l' size='340' side='right' caption='[[1u2l]], [[Resolution\|resolution]] 2.30Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1u2l]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Escherichia_coli Escherichia~~ coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1U2L OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1U2L FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1u2l]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1U2L OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1U2L FirstGlance]. <br>
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1u2j\|1u2j]], [[1u2k\|1u2k]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1u2j\|1u2j]], [[1u2k\|1u2k]]</td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">katG ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 ~~Escherichia~~ coli])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">katG ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 "Bacillus coli" Migula 1895])</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Catalase Catalase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.11.1.6 1.11.1.6] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Catalase Catalase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.11.1.6 1.11.1.6] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1u2l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1u2l OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1u2l RCSB], [http://www.ebi.ac.uk/pdbsum/1u2l PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1u2l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1u2l OCA], [http://pdbe.org/1u2l PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1u2l RCSB], [http://www.ebi.ac.uk/pdbsum/1u2l PDBsum]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[http://www.uniprot.org/uniprot/~~CATA_ECOLI CATA_ECOLI~~]] Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity. Displays also NADH oxidase, INH lyase and isonicotinoyl-NAD synthase activity.~~[HAMAP-Rule~~:~~MF_01961]~~	+	[[http://www.uniprot.org/uniprot/KATG_ECOLI KATG_ECOLI]] Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity. Displays also NADH oxidase, INH lyase and isonicotinoyl-NAD synthase activity.<ref>PMID:18178143</ref> <ref>PMID:23416055</ref> <ref>PMID:374409</ref>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 28:		Line 28:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 1u2l" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
Line 35:		Line 36:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Bacillus coli migula 1895]]
	[[Category: Catalase]]		[[Category: Catalase]]
-	[[Category: Escherichia coli]]
	[[Category: Carpena, X]]		[[Category: Carpena, X]]
	[[Category: Fita, I]]		[[Category: Fita, I]]

OCA at 21:56, 24 December 2014

OCA — Wed, 24 Dec 2014 21:56:12 GMT

←Older revision		Revision as of 21:56, 24 December 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1u2l]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1U2L OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1U2L FirstGlance]. <br>		<table><tr><td colspan='2'>[[1u2l]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1U2L OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1U2L FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1u2j\|1u2j]], [[1u2k\|1u2k]]</td></tr>	+	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1u2j\|1u2j]], [[1u2k\|1u2k]]</td></tr>
-	<tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">katG ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 Escherichia coli])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">katG ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 Escherichia coli])</td></tr>
-	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Catalase Catalase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.11.1.6 1.11.1.6] </span></td></tr>	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Catalase Catalase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.11.1.6 1.11.1.6] </span></td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1u2l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1u2l OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1u2l RCSB], [http://www.ebi.ac.uk/pdbsum/1u2l PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1u2l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1u2l OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1u2l RCSB], [http://www.ebi.ac.uk/pdbsum/1u2l PDBsum]</span></td></tr>
-	<table>	+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/CATA_ECOLI CATA_ECOLI]] Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity. Displays also NADH oxidase, INH lyase and isonicotinoyl-NAD synthase activity.[HAMAP-Rule:MF_01961]
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 35:		Line 37:
	[[Category: Catalase]]		[[Category: Catalase]]
	[[Category: Escherichia coli]]		[[Category: Escherichia coli]]
-	[[Category: Carpena, X.]]	+	[[Category: Carpena, X]]
-	[[Category: Fita, I.]]	+	[[Category: Fita, I]]
-	[[Category: Loewen, P C.]]	+	[[Category: Loewen, P C]]
-	[[Category: Melik-Adamyan, W.]]	+	[[Category: Melik-Adamyan, W]]
	[[Category: C-terminal domain]]		[[Category: C-terminal domain]]
	[[Category: Catalase-peroxidase]]		[[Category: Catalase-peroxidase]]
	[[Category: Katg]]		[[Category: Katg]]
	[[Category: Oxidoreductase]]		[[Category: Oxidoreductase]]

OCA at 00:07, 29 September 2014

OCA — Mon, 29 Sep 2014 00:07:48 GMT

←Older revision		Revision as of 00:07, 29 September 2014
Line 1:		Line 1:
-	[[~~Image:~~1u2l.~~png~~\|~~left~~\|200px]]	+	==Crystal structure of the C-terminal domain from the catalase-peroxidase KatG of Escherichia coli (P1)==
		+	<StructureSection load='1u2l' size='340' side='right' caption='[[1u2l]], [[Resolution\|resolution]] 2.30Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[1u2l]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1U2L OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1U2L FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1u2j\|1u2j]], [[1u2k\|1u2k]]</td></tr>
		+	<tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">katG ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 Escherichia coli])</td></tr>
		+	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Catalase Catalase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.11.1.6 1.11.1.6] </span></td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1u2l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1u2l OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1u2l RCSB], [http://www.ebi.ac.uk/pdbsum/1u2l PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/u2/1u2l_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Catalase-peroxidases or KatGs, the apparent in vivo activators of the anti-tubercular pro-drug isoniazid, are active as homodimers, each subunit having two distinct but sequence- and structure-related domains. The N-terminal domain contains the haem group and is catalytically active, while the C-terminal domain lacks the cofactor. The C-terminal domain of KatG from Escherichia coli is expressed as a soluble protein which has been crystallized in triclinic, orthorhombic and tetragonal crystal forms. Packing in the orthorhombic crystals, with eight molecules in the asymmetric unit, follows the pattern of commensurate modulated structures, which explains the diversity of pseudo-origin peaks observed in the native Patterson map. The different crystal forms arise from variations in the length and sequence of the N-terminal extensions in the different constructs. Despite the variability in the N-terminal region, the overall domain conformations beginning with Pro437 are very similar both to each other and to the C-terminal domains within the native structures of the KatGs from Haloarcula marismortui and Burkholderia pseudomallei. Some structural reorganization in the C-terminal domain relative to the N-terminal domain has evolved to compensate for the absence of the haem group. A high percentage of the residues in the C-terminal domains of KatG proteins from different sources are highly conserved and these residues are spread uniformly throughout the domain. The easily folded nature and retention of structure in the C-terminal domain suggests that it may serve as a platform for the folding of the N-terminal domain and for stabilization of the molecular dimer.

-	~~{{STRUCTURE_1u2l\| PDB=1u2l \| SCENE= }}~~	+	Structure of the C-terminal domain of the catalase-peroxidase KatG from Escherichia coli.,Carpena X, Melik-Adamyan W, Loewen PC, Fita I Acta Crystallogr D Biol Crystallogr. 2004 Oct;60(Pt 10):1824-32. Epub 2004, Sep 23. PMID:15388929<ref>PMID:15388929</ref>

-	~~===Crystal structure~~ of the ~~C-terminal domain from the catalase-peroxidase KatG of Escherichia coli (P1)===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_15388929}}~~	+
-		+
-	~~==About this Structure==~~	+
-	~~[[1u2l]] is a 2 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Escherichia_coli Escherichia coli]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=1U2L OCA].~~	+

	==See Also==		==See Also==
	*[[Catalase\|Catalase]]		*[[Catalase\|Catalase]]
-		+	== References ==
-	==~~Reference~~==	+	<references/>
-	<~~ref group="xtra">PMID:015388929<~~/~~ref~~><~~references group="xtra"~~/>	+	__TOC__
		+	</StructureSection>
	[[Category: Catalase]]		[[Category: Catalase]]
	[[Category: Escherichia coli]]		[[Category: Escherichia coli]]

OCA at 09:31, 20 October 2012

OCA — Sat, 20 Oct 2012 09:31:50 GMT

←Older revision		Revision as of 09:31, 20 October 2012
Line 8:		Line 8:

	==About this Structure==		==About this Structure==
-	[[1u2l]] is a 2 chain structure ~~of [[Catalase]]~~ with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1U2L OCA].	+	[[1u2l]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1U2L OCA].

	==See Also==		==See Also==

OCA: Protected "1u2l" [edit=sysop:move=sysop]

OCA — Wed, 25 Jul 2012 23:09:47 GMT

Protected "1u2l" [edit=sysop:move=sysop]

←Older revision

Revision as of 23:09, 25 July 2012

OCA at 23:09, 25 July 2012

OCA — Wed, 25 Jul 2012 23:09:44 GMT

←Older revision		Revision as of 23:09, 25 July 2012
Line 1:		Line 1:
-	{{Seed}}
	[[Image:1u2l.png\|left\|200px]]		[[Image:1u2l.png\|left\|200px]]

-	<!--
-	The line below this paragraph, containing "STRUCTURE_1u2l", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
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	{{STRUCTURE_1u2l\| PDB=1u2l \| SCENE= }}		{{STRUCTURE_1u2l\| PDB=1u2l \| SCENE= }}

	===Crystal structure of the C-terminal domain from the catalase-peroxidase KatG of Escherichia coli (P1)===		===Crystal structure of the C-terminal domain from the catalase-peroxidase KatG of Escherichia coli (P1)===

-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_15388929}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where 15388929 is the PubMed ID number.
-	-->
	{{ABSTRACT_PUBMED_15388929}}		{{ABSTRACT_PUBMED_15388929}}

	==About this Structure==		==About this Structure==
-	~~1U2L~~ is a 2 ~~chains~~ structure of ~~sequences~~ from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1U2L OCA].	+	[[1u2l]] is a 2 chain structure of [[Catalase]] with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1U2L OCA].
		+
		+	==See Also==
		+	*[[Catalase\|Catalase]]

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~15388929~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:015388929</ref><references group="xtra"/>
	[[Category: Catalase]]		[[Category: Catalase]]
	[[Category: Escherichia coli]]		[[Category: Escherichia coli]]
Line 33:		Line 24:
	[[Category: Catalase-peroxidase]]		[[Category: Catalase-peroxidase]]
	[[Category: Katg]]		[[Category: Katg]]
-		+	[[Category: Oxidoreductase]]
-	~~''Page seeded by~~ [~~http~~:~~//oca.weizmann.ac.il/oca OCA~~ ] ~~on Mon Feb 16 20:32:40 2009''~~	+