1ua8 - Revision history

OCA at 07:30, 25 October 2023

OCA — Wed, 25 Oct 2023 07:30:45 GMT

←Older revision		Revision as of 07:30, 25 October 2023
Line 3:		Line 3:
	<StructureSection load='1ua8' size='340' side='right'caption='[[1ua8]], [[Resolution\|resolution]] 1.90Å' scene=''>		<StructureSection load='1ua8' size='340' side='right'caption='[[1ua8]], [[Resolution\|resolution]] 1.90Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1ua8]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/~~"bacillus_coli"_migula_1895 "bacillus~~ coli~~" migula 1895~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UA8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1UA8 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1ua8]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UA8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1UA8 FirstGlance]. <br>
-	</td></tr><tr id='~~related~~'><td class="sblockLbl"><b>[[~~Related_structure~~\|~~Related~~:]]</b></td><td class="sblockDat">~~<div style='overflow: auto; max~~-~~height: 3em;'>[[1iwl\|1iwl]]~~, [[~~1iwm~~\|~~1iwm~~]]~~, [[1iwn\|1iwn]]</div>~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.9Å</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ua8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ua8 OCA], [https://pdbe.org/1ua8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ua8 RCSB], [https://www.ebi.ac.uk/pdbsum/1ua8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ua8 ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ua8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ua8 OCA], [https://pdbe.org/1ua8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ua8 RCSB], [https://www.ebi.ac.uk/pdbsum/1ua8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ua8 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[https://www.uniprot.org/uniprot/LOLA_ECOLI LOLA_ECOLI]] Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane); the inner membrane retention signal functions at the release step.<ref>PMID:11758943</ref> May act as a regulator of the RCS-phosphorelay signal transduction pathway.<ref>PMID:11758943</ref>	+	[https://www.uniprot.org/uniprot/LOLA_ECOLI LOLA_ECOLI] Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane); the inner membrane retention signal functions at the release step.<ref>PMID:11758943</ref> May act as a regulator of the RCS-phosphorelay signal transduction pathway.<ref>PMID:11758943</ref>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 32:		Line 32:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Bacillus~~ coli ~~migula 1895~~]]	+	[[Category: Escherichia coli]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Matsuyama, S]]	+	[[Category: Matsuyama S]]
-	[[Category: Miki, K]]	+	[[Category: Miki K]]
-	[[Category: Miyatake, H]]	+	[[Category: Miyatake H]]
-	[[Category: Takeda, K]]	+	[[Category: Takeda K]]
-	[[Category: Tokuda, H]]	+	[[Category: Tokuda H]]
-	[[Category: Yokota, N]]	+	[[Category: Yokota N]]
-	~~[[Category: Protein transport]]~~	+
-	~~[[Category: Unclosed beta barrel~~]]	+

OCA at 09:38, 29 September 2021

OCA — Wed, 29 Sep 2021 09:38:29 GMT

←Older revision		Revision as of 09:38, 29 September 2021
Line 3:		Line 3:
	<StructureSection load='1ua8' size='340' side='right'caption='[[1ua8]], [[Resolution\|resolution]] 1.90Å' scene=''>		<StructureSection load='1ua8' size='340' side='right'caption='[[1ua8]], [[Resolution\|resolution]] 1.90Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1ua8]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UA8 OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1UA8 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1ua8]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UA8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1UA8 FirstGlance]. <br>
-	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1iwl\|1iwl]], [[1iwm\|1iwm]], [[1iwn\|1iwn]]</td></tr>	+	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1iwl\|1iwl]], [[1iwm\|1iwm]], [[1iwn\|1iwn]]</div></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1ua8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ua8 OCA], [~~http~~://pdbe.org/1ua8 PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=1ua8 RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/1ua8 PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=1ua8 ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ua8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ua8 OCA], [https://pdbe.org/1ua8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ua8 RCSB], [https://www.ebi.ac.uk/pdbsum/1ua8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ua8 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[~~http~~://www.uniprot.org/uniprot/LOLA_ECOLI LOLA_ECOLI]] Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane); the inner membrane retention signal functions at the release step.<ref>PMID:11758943</ref> May act as a regulator of the RCS-phosphorelay signal transduction pathway.<ref>PMID:11758943</ref>	+	[[https://www.uniprot.org/uniprot/LOLA_ECOLI LOLA_ECOLI]] Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane); the inner membrane retention signal functions at the release step.<ref>PMID:11758943</ref> May act as a regulator of the RCS-phosphorelay signal transduction pathway.<ref>PMID:11758943</ref>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]

OCA at 13:54, 25 December 2019

OCA — Wed, 25 Dec 2019 13:54:13 GMT

←Older revision		Revision as of 13:54, 25 December 2019
Line 1:		Line 1:

	==Crystal structure of the lipoprotein localization factor, LolA==		==Crystal structure of the lipoprotein localization factor, LolA==
-	<StructureSection load='1ua8' size='340' side='right' caption='[[1ua8]], [[Resolution\|resolution]] 1.90Å' scene=''>	+	<StructureSection load='1ua8' size='340' side='right'caption='[[1ua8]], [[Resolution\|resolution]] 1.90Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1ua8]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UA8 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1UA8 FirstGlance]. <br>		<table><tr><td colspan='2'>[[1ua8]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UA8 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1UA8 FirstGlance]. <br>
Line 33:		Line 33:
	</StructureSection>		</StructureSection>
	[[Category: Bacillus coli migula 1895]]		[[Category: Bacillus coli migula 1895]]
		+	[[Category: Large Structures]]
	[[Category: Matsuyama, S]]		[[Category: Matsuyama, S]]
	[[Category: Miki, K]]		[[Category: Miki, K]]

OCA at 08:43, 21 March 2018

OCA — Wed, 21 Mar 2018 08:43:47 GMT

←Older revision		Revision as of 08:43, 21 March 2018
Line 1:		Line 1:
		+
	==Crystal structure of the lipoprotein localization factor, LolA==		==Crystal structure of the lipoprotein localization factor, LolA==
	<StructureSection load='1ua8' size='340' side='right' caption='[[1ua8]], [[Resolution\|resolution]] 1.90Å' scene=''>		<StructureSection load='1ua8' size='340' side='right' caption='[[1ua8]], [[Resolution\|resolution]] 1.90Å' scene=''>
Line 4:		Line 5:
	<table><tr><td colspan='2'>[[1ua8]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UA8 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1UA8 FirstGlance]. <br>		<table><tr><td colspan='2'>[[1ua8]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UA8 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1UA8 FirstGlance]. <br>
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1iwl\|1iwl]], [[1iwm\|1iwm]], [[1iwn\|1iwn]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1iwl\|1iwl]], [[1iwm\|1iwm]], [[1iwn\|1iwn]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ua8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ua8 OCA], [http://pdbe.org/1ua8 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1ua8 RCSB], [http://www.ebi.ac.uk/pdbsum/1ua8 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ua8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ua8 OCA], [http://pdbe.org/1ua8 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1ua8 RCSB], [http://www.ebi.ac.uk/pdbsum/1ua8 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1ua8 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 12:		Line 13:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ua/1ua8_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ua/1ua8_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>

OCA at 20:58, 7 February 2016

OCA — Sun, 07 Feb 2016 20:58:51 GMT

←Older revision		Revision as of 20:58, 7 February 2016
Line 16:		Line 16:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1ua8 ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 04:56, 10 September 2015

OCA — Thu, 10 Sep 2015 04:56:21 GMT

←Older revision		Revision as of 04:56, 10 September 2015
Line 2:		Line 2:
	<StructureSection load='1ua8' size='340' side='right' caption='[[1ua8]], [[Resolution\|resolution]] 1.90Å' scene=''>		<StructureSection load='1ua8' size='340' side='right' caption='[[1ua8]], [[Resolution\|resolution]] 1.90Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1ua8]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Escherichia_coli Escherichia~~ coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UA8 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1UA8 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1ua8]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UA8 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1UA8 FirstGlance]. <br>
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1iwl\|1iwl]], [[1iwm\|1iwm]], [[1iwn\|1iwn]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1iwl\|1iwl]], [[1iwm\|1iwm]], [[1iwn\|1iwn]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ua8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ua8 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1ua8 RCSB], [http://www.ebi.ac.uk/pdbsum/1ua8 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ua8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ua8 OCA], [http://pdbe.org/1ua8 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1ua8 RCSB], [http://www.ebi.ac.uk/pdbsum/1ua8 PDBsum]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 26:		Line 26:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 1ua8" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Escherichia~~ coli]]	+	[[Category: Bacillus coli migula 1895]]
	[[Category: Matsuyama, S]]		[[Category: Matsuyama, S]]
	[[Category: Miki, K]]		[[Category: Miki, K]]

OCA at 18:12, 24 December 2014

OCA — Wed, 24 Dec 2014 18:12:30 GMT

←Older revision		Revision as of 18:12, 24 December 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1ua8]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UA8 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1UA8 FirstGlance]. <br>		<table><tr><td colspan='2'>[[1ua8]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UA8 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1UA8 FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1iwl\|1iwl]], [[1iwm\|1iwm]], [[1iwn\|1iwn]]</td></tr>	+	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1iwl\|1iwl]], [[1iwm\|1iwm]], [[1iwn\|1iwn]]</td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ua8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ua8 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1ua8 RCSB], [http://www.ebi.ac.uk/pdbsum/1ua8 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ua8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ua8 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1ua8 RCSB], [http://www.ebi.ac.uk/pdbsum/1ua8 PDBsum]</span></td></tr>
-	<table>	+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/LOLA_ECOLI LOLA_ECOLI]] Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane); the inner membrane retention signal functions at the release step.<ref>PMID:11758943</ref> May act as a regulator of the RCS-phosphorelay signal transduction pathway.<ref>PMID:11758943</ref>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 29:		Line 31:
	</StructureSection>		</StructureSection>
	[[Category: Escherichia coli]]		[[Category: Escherichia coli]]
-	[[Category: Matsuyama, S.]]	+	[[Category: Matsuyama, S]]
-	[[Category: Miki, K.]]	+	[[Category: Miki, K]]
-	[[Category: Miyatake, H.]]	+	[[Category: Miyatake, H]]
-	[[Category: Takeda, K.]]	+	[[Category: Takeda, K]]
-	[[Category: Tokuda, H.]]	+	[[Category: Tokuda, H]]
-	[[Category: Yokota, N.]]	+	[[Category: Yokota, N]]
	[[Category: Protein transport]]		[[Category: Protein transport]]
	[[Category: Unclosed beta barrel]]		[[Category: Unclosed beta barrel]]

OCA at 19:05, 29 September 2014

OCA — Mon, 29 Sep 2014 19:05:49 GMT

←Older revision		Revision as of 19:05, 29 September 2014
Line 1:		Line 1:
-	[[~~Image:~~1ua8.~~png~~\|~~left~~\|200px]]	+	==Crystal structure of the lipoprotein localization factor, LolA==
		+	<StructureSection load='1ua8' size='340' side='right' caption='[[1ua8]], [[Resolution\|resolution]] 1.90Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[1ua8]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UA8 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1UA8 FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1iwl\|1iwl]], [[1iwm\|1iwm]], [[1iwn\|1iwn]]</td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ua8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ua8 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1ua8 RCSB], [http://www.ebi.ac.uk/pdbsum/1ua8 PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ua/1ua8_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Lipoproteins having a lipid-modified cysteine at the N-terminus are localized on either the inner or the outer membrane of Escherichia coli depending on the residue at position 2. Five Lol proteins involved in the sorting and membrane localization of lipoprotein are highly conserved in Gram-negative bacteria. We determined the crystal structures of a periplasmic chaperone, LolA, and an outer membrane lipoprotein receptor, LolB. Despite their dissimilar amino acid sequences, the structures of LolA and LolB are strikingly similar to each other. Both have a hydrophobic cavity consisting of an unclosed beta barrel and an alpha-helical lid. The cavity represents a possible binding site for the lipid moiety of lipoproteins. Detailed structural differences between the two proteins provide significant insights into the molecular mechanisms underlying the energy-independent transfer of lipoproteins from LolA to LolB and from LolB to the outer membrane. Furthermore, the structures of both LolA and LolB determined from different crystal forms revealed the distinct structural dynamics regarding the association and dissociation of lipoproteins. The results are discussed in the context of the current model for the lipoprotein transfer from the inner to the outer membrane through a hydrophilic environment.

-	~~{{STRUCTURE_1ua8\| PDB=1ua8 \| SCENE= }}~~	+	Crystal structures of bacterial lipoprotein localization factors, LolA and LolB.,Takeda K, Miyatake H, Yokota N, Matsuyama S, Tokuda H, Miki K EMBO J. 2003 Jul 1;22(13):3199-209. PMID:12839983<ref>PMID:12839983</ref>

-	~~===Crystal structure~~ of the ~~lipoprotein localization factor, LolA===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_12839983}}~~	+	== References ==
-		+	<references/>
-	~~==About this Structure==~~	+	__TOC__
-	~~[[1ua8]] is a 1 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Escherichia_coli Escherichia coli]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=1UA8 OCA].~~	+	</StructureSection>
-		+
-	==~~Reference~~==	+
-	<~~ref group="xtra">PMID:012839983<~~/~~ref~~><~~references group="xtra"~~/>	+
	[[Category: Escherichia coli]]		[[Category: Escherichia coli]]
	[[Category: Matsuyama, S.]]		[[Category: Matsuyama, S.]]

OCA: Protected "1ua8" [edit=sysop:move=sysop]

OCA — Sat, 05 Jan 2013 11:58:11 GMT

Protected "1ua8" [edit=sysop:move=sysop]

←Older revision

Revision as of 11:58, 5 January 2013

OCA at 11:58, 5 January 2013

OCA — Sat, 05 Jan 2013 11:58:10 GMT

←Older revision		Revision as of 11:58, 5 January 2013
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-	{{Seed}}
	[[Image:1ua8.png\|left\|200px]]		[[Image:1ua8.png\|left\|200px]]

-	<!--
-	The line below this paragraph, containing "STRUCTURE_1ua8", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
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	{{STRUCTURE_1ua8\| PDB=1ua8 \| SCENE= }}		{{STRUCTURE_1ua8\| PDB=1ua8 \| SCENE= }}

	===Crystal structure of the lipoprotein localization factor, LolA===		===Crystal structure of the lipoprotein localization factor, LolA===

-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_12839983}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where 12839983 is the PubMed ID number.
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	{{ABSTRACT_PUBMED_12839983}}		{{ABSTRACT_PUBMED_12839983}}

	==About this Structure==		==About this Structure==
-	~~1UA8~~ is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UA8 OCA].	+	[[1ua8]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UA8 OCA].

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~12839983~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:012839983</ref><references group="xtra"/>
	[[Category: Escherichia coli]]		[[Category: Escherichia coli]]
	[[Category: Matsuyama, S.]]		[[Category: Matsuyama, S.]]
Line 31:		Line 19:
	[[Category: Tokuda, H.]]		[[Category: Tokuda, H.]]
	[[Category: Yokota, N.]]		[[Category: Yokota, N.]]
		+	[[Category: Protein transport]]
	[[Category: Unclosed beta barrel]]		[[Category: Unclosed beta barrel]]
-
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 16:28:02 2009''