1uan - Revision history

OCA at 23:50, 27 December 2023

OCA — Wed, 27 Dec 2023 23:50:16 GMT

←Older revision		Revision as of 23:50, 27 December 2023
Line 3:		Line 3:
	<StructureSection load='1uan' size='340' side='right'caption='[[1uan]], [[Resolution\|resolution]] 2.00Å' scene=''>		<StructureSection load='1uan' size='340' side='right'caption='[[1uan]], [[Resolution\|resolution]] 2.00Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1uan]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/~~"flavobacterium_thermophilum"_yoshida_and_oshima_1971 "flavobacterium thermophilum" yoshida and oshima 1971~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UAN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1UAN FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1uan]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UAN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1UAN FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1uan FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1uan OCA], [https://pdbe.org/1uan PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1uan RCSB], [https://www.ebi.ac.uk/pdbsum/1uan PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1uan ProSAT], [https://www.topsan.org/Proteins/RSGI/1uan TOPSAN]</span></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2Å</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1uan FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1uan OCA], [https://pdbe.org/1uan PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1uan RCSB], [https://www.ebi.ac.uk/pdbsum/1uan PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1uan ProSAT], [https://www.topsan.org/Proteins/RSGI/1uan TOPSAN]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/Q84BR2_THETH Q84BR2_THETH]
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 29:		Line 32:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Flavobacterium thermophilum yoshida and oshima 1971]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Handa, N]]	+	[[Category: Thermus thermophilus]]
-	[[Category: Kinoshita, K]]	+	[[Category: Handa N]]
-	[[Category: Kuramitsu, S]]	+	[[Category: Kinoshita K]]
-	[[Category: Nakamura, H]]	+	[[Category: Kuramitsu S]]
-	[[Category: Ota, M]]	+	[[Category: Nakamura H]]
-	[[Category: Park, S Y]]	+	[[Category: Ota M]]
-	~~[[Category: Structural genomic~~]]	+	[[Category: Park S-Y]]
-	[[Category: Shirouzu, M]]	+	[[Category: Shirouzu M]]
-	[[Category: Tame~~, J R.H~~]]	+	[[Category: Tame JRH]]
-	[[Category: Terada, T]]	+	[[Category: Terada T]]
-	[[Category: Yokoyama, S]]	+	[[Category: Yokoyama S]]
-	~~[[Category: Rossmann-like]]~~	+
-	~~[[Category: Rsgi]]~~	+
-	~~[[Category: Unknown function~~]]	+

OCA at 09:38, 29 September 2021

OCA — Wed, 29 Sep 2021 09:38:49 GMT

←Older revision		Revision as of 09:38, 29 September 2021
Line 3:		Line 3:
	<StructureSection load='1uan' size='340' side='right'caption='[[1uan]], [[Resolution\|resolution]] 2.00Å' scene=''>		<StructureSection load='1uan' size='340' side='right'caption='[[1uan]], [[Resolution\|resolution]] 2.00Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1uan]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/"flavobacterium_thermophilum"_yoshida_and_oshima_1971 "flavobacterium thermophilum" yoshida and oshima 1971]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UAN OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1UAN FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1uan]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/"flavobacterium_thermophilum"_yoshida_and_oshima_1971 "flavobacterium thermophilum" yoshida and oshima 1971]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UAN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1UAN FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1uan FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1uan OCA], [~~http~~://pdbe.org/1uan PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=1uan RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/1uan PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=1uan ProSAT], [~~http~~://www.topsan.org/Proteins/RSGI/1uan TOPSAN]</span></td></tr>	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1uan FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1uan OCA], [https://pdbe.org/1uan PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1uan RCSB], [https://www.ebi.ac.uk/pdbsum/1uan PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1uan ProSAT], [https://www.topsan.org/Proteins/RSGI/1uan TOPSAN]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==

OCA at 14:08, 25 December 2019

OCA — Wed, 25 Dec 2019 14:08:13 GMT

←Older revision		Revision as of 14:08, 25 December 2019
Line 1:		Line 1:

	==Crystal structure of the conserved protein TT1542 from Thermus thermophilus HB8==		==Crystal structure of the conserved protein TT1542 from Thermus thermophilus HB8==
-	<StructureSection load='1uan' size='340' side='right' caption='[[1uan]], [[Resolution\|resolution]] 2.00Å' scene=''>	+	<StructureSection load='1uan' size='340' side='right'caption='[[1uan]], [[Resolution\|resolution]] 2.00Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1uan]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/"flavobacterium_thermophilum"_yoshida_and_oshima_1971 "flavobacterium thermophilum" yoshida and oshima 1971]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UAN OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1UAN FirstGlance]. <br>		<table><tr><td colspan='2'>[[1uan]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/"flavobacterium_thermophilum"_yoshida_and_oshima_1971 "flavobacterium thermophilum" yoshida and oshima 1971]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UAN OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1UAN FirstGlance]. <br>
Line 30:		Line 30:
	</StructureSection>		</StructureSection>
	[[Category: Flavobacterium thermophilum yoshida and oshima 1971]]		[[Category: Flavobacterium thermophilum yoshida and oshima 1971]]
		+	[[Category: Large Structures]]
	[[Category: Handa, N]]		[[Category: Handa, N]]
	[[Category: Kinoshita, K]]		[[Category: Kinoshita, K]]

OCA at 08:57, 21 March 2018

OCA — Wed, 21 Mar 2018 08:57:32 GMT

←Older revision		Revision as of 08:57, 21 March 2018
Line 1:		Line 1:
		+
	==Crystal structure of the conserved protein TT1542 from Thermus thermophilus HB8==		==Crystal structure of the conserved protein TT1542 from Thermus thermophilus HB8==
	<StructureSection load='1uan' size='340' side='right' caption='[[1uan]], [[Resolution\|resolution]] 2.00Å' scene=''>		<StructureSection load='1uan' size='340' side='right' caption='[[1uan]], [[Resolution\|resolution]] 2.00Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1uan]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/"flavobacterium_thermophilum"_yoshida_and_oshima_1971 "flavobacterium thermophilum" yoshida and oshima 1971]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UAN OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1UAN FirstGlance]. <br>		<table><tr><td colspan='2'>[[1uan]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/"flavobacterium_thermophilum"_yoshida_and_oshima_1971 "flavobacterium thermophilum" yoshida and oshima 1971]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UAN OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1UAN FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1uan FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1uan OCA], [http://pdbe.org/1uan PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1uan RCSB], [http://www.ebi.ac.uk/pdbsum/1uan PDBsum], [http://www.topsan.org/Proteins/RSGI/1uan TOPSAN]</span></td></tr>	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1uan FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1uan OCA], [http://pdbe.org/1uan PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1uan RCSB], [http://www.ebi.ac.uk/pdbsum/1uan PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1uan ProSAT], [http://www.topsan.org/Proteins/RSGI/1uan TOPSAN]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 9:		Line 10:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ua/1uan_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ua/1uan_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>

OCA at 12:04, 8 February 2016

OCA — Mon, 08 Feb 2016 12:04:51 GMT

←Older revision		Revision as of 12:04, 8 February 2016
Line 13:		Line 13:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1uan ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 11:24, 10 September 2015

OCA — Thu, 10 Sep 2015 11:24:10 GMT

←Older revision		Revision as of 11:24, 10 September 2015
Line 2:		Line 2:
	<StructureSection load='1uan' size='340' side='right' caption='[[1uan]], [[Resolution\|resolution]] 2.00Å' scene=''>		<StructureSection load='1uan' size='340' side='right' caption='[[1uan]], [[Resolution\|resolution]] 2.00Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1uan]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Thermus_thermophilus Thermus thermophilus~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UAN OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1UAN FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1uan]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/"flavobacterium_thermophilum"_yoshida_and_oshima_1971 "flavobacterium thermophilum" yoshida and oshima 1971]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UAN OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1UAN FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1uan FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1uan OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1uan RCSB], [http://www.ebi.ac.uk/pdbsum/1uan PDBsum], [http://www.topsan.org/Proteins/RSGI/1uan TOPSAN]</span></td></tr>	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1uan FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1uan OCA], [http://pdbe.org/1uan PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1uan RCSB], [http://www.ebi.ac.uk/pdbsum/1uan PDBsum], [http://www.topsan.org/Proteins/RSGI/1uan TOPSAN]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 23:		Line 23:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 1uan" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Thermus thermophilus~~]]	+	[[Category: Flavobacterium thermophilum yoshida and oshima 1971]]
	[[Category: Handa, N]]		[[Category: Handa, N]]
	[[Category: Kinoshita, K]]		[[Category: Kinoshita, K]]

OCA at 13:58, 6 January 2015

OCA — Tue, 06 Jan 2015 13:58:12 GMT

←Older revision		Revision as of 13:58, 6 January 2015
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1uan]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UAN OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1UAN FirstGlance]. <br>		<table><tr><td colspan='2'>[[1uan]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UAN OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1UAN FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1uan FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1uan OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1uan RCSB], [http://www.ebi.ac.uk/pdbsum/1uan PDBsum], [http://www.topsan.org/Proteins/RSGI/1uan TOPSAN]</span></td></tr>	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1uan FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1uan OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1uan RCSB], [http://www.ebi.ac.uk/pdbsum/1uan PDBsum], [http://www.topsan.org/Proteins/RSGI/1uan TOPSAN]</span></td></tr>
-	<table>	+	</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 28:		Line 28:
	</StructureSection>		</StructureSection>
	[[Category: Thermus thermophilus]]		[[Category: Thermus thermophilus]]
-	[[Category: Handa, N.]]	+	[[Category: Handa, N]]
-	[[Category: Kinoshita, K.]]	+	[[Category: Kinoshita, K]]
-	[[Category: Kuramitsu, S.]]	+	[[Category: Kuramitsu, S]]
-	[[Category: Nakamura, H.]]	+	[[Category: Nakamura, H]]
-	[[Category: Ota, M.]]	+	[[Category: Ota, M]]
-	[[Category: Park, S Y.]]	+	[[Category: Park, S Y]]
-	[[Category: ~~RSGI, RIKEN~~ Structural ~~Genomics/Proteomics Initiative.~~]]	+	[[Category: Structural genomic]]
-	[[Category: Shirouzu, M.]]	+	[[Category: Shirouzu, M]]
-	[[Category: Tame, J R.H.]]	+	[[Category: Tame, J R.H]]
-	[[Category: Terada, T.]]	+	[[Category: Terada, T]]
-	[[Category: Yokoyama, S~~.]]~~	+	[[Category: Yokoyama, S]]
-	~~[[Category: Riken structural genomics/proteomics initiative~~]]	+
	[[Category: Rossmann-like]]		[[Category: Rossmann-like]]
	[[Category: Rsgi]]		[[Category: Rsgi]]
-	[[Category: Structural genomic]]
	[[Category: Unknown function]]		[[Category: Unknown function]]

OCA at 19:14, 29 September 2014

OCA — Mon, 29 Sep 2014 19:14:18 GMT

←Older revision		Revision as of 19:14, 29 September 2014
Line 1:		Line 1:
-	[[~~Image~~:1uan.~~png\|left~~\|200px]]	+	==Crystal structure of the conserved protein TT1542 from Thermus thermophilus HB8==
		+	<StructureSection load='1uan' size='340' side='right' caption='[[1uan]], [[Resolution\|resolution]] 2.00Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[1uan]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UAN OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1UAN FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1uan FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1uan OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1uan RCSB], [http://www.ebi.ac.uk/pdbsum/1uan PDBsum], [http://www.topsan.org/Proteins/RSGI/1uan TOPSAN]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ua/1uan_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	The TT1542 protein from Thermus thermophilus HB8 is annotated as a conserved hypothetical protein, and belongs to the DUF158 family in the Pfam database. A BLAST search revealed that homologs of TT1542 are present in a wide range of organisms. The TT1542 homologs in eukaryotes, PIG-L in mammals, and GPI12 in yeast and protozoa, have N-acetylglucosaminylphosphatidylinositol (GlcNAc-PI) de-N-acetylase activity. Although most of the homologs in prokaryotes are hypothetical and have no known function, Rv1082 and Rv1170 from Mycobacterium tuberculosis are enzymes involved in the mycothiol detoxification pathway. Here we report the crystal structure of the TT1542 protein at 2.0 A resolution, which represents the first structure for this superfamily of proteins. The structure of the TT1542 monomer consists of a twisted beta-sheet composed of six parallel beta-strands and one antiparallel beta-strand (with the strand order 3-2-1-4-5-7-6) sandwiched between six alpha-helices. The N-terminal five beta-strands and four alpha-helices form an incomplete Rossmann fold-like structure. The structure shares some similarity to the sugar-processing enzymes with Rossmann fold-like domains, especially those of the GPGTF (glycogen phosphorylase/glycosyl transferase) superfamily, and also to the NAD(P)-binding Rossmann fold domains. TT1542 is a homohexamer in the crystal and in solution, the six monomers forming a cylindrical structure. Putative active sites are suggested by the structure and conserved amino acid residues.

-	~~{{STRUCTURE_1uan\| PDB=1uan \| SCENE= }}~~	+	Crystal structure of the conserved protein TT1542 from Thermus thermophilus HB8.,Handa N, Terada T, Kamewari Y, Hamana H, Tame JR, Park SY, Kinoshita K, Ota M, Nakamura H, Kuramitsu S, Shirouzu M, Yokoyama S Protein Sci. 2003 Aug;12(8):1621-32. PMID:12876312<ref>PMID:12876312</ref>

-	~~===Crystal structure~~ of the ~~conserved protein TT1542 from Thermus thermophilus HB8===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_12876312}}~~	+	== References ==
-		+	<references/>
-	~~==About this Structure==~~	+	__TOC__
-	~~[[1uan]] is a 2 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Thermus_thermophilus Thermus thermophilus]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=1UAN OCA].~~	+	</StructureSection>
-		+
-	==~~Reference~~==	+
-	<~~ref group="xtra">PMID:012876312<~~/~~ref~~><~~references group="xtra"~~/>	+
	[[Category: Thermus thermophilus]]		[[Category: Thermus thermophilus]]
	[[Category: Handa, N.]]		[[Category: Handa, N.]]

OCA: Protected "1uan" [edit=sysop:move=sysop]

OCA — Sat, 05 Jan 2013 12:09:50 GMT

Protected "1uan" [edit=sysop:move=sysop]

←Older revision

Revision as of 12:09, 5 January 2013

OCA at 12:09, 5 January 2013

OCA — Sat, 05 Jan 2013 12:09:48 GMT

←Older revision		Revision as of 12:09, 5 January 2013
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-	{{Seed}}
	[[Image:1uan.png\|left\|200px]]		[[Image:1uan.png\|left\|200px]]

-	<!--
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	{{STRUCTURE_1uan\| PDB=1uan \| SCENE= }}		{{STRUCTURE_1uan\| PDB=1uan \| SCENE= }}

	===Crystal structure of the conserved protein TT1542 from Thermus thermophilus HB8===		===Crystal structure of the conserved protein TT1542 from Thermus thermophilus HB8===

-
-	<!--
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	{{ABSTRACT_PUBMED_12876312}}		{{ABSTRACT_PUBMED_12876312}}

	==About this Structure==		==About this Structure==
-	~~1UAN~~ is a 2 ~~chains~~ structure ~~of sequences~~ from [http://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UAN OCA].	+	[[1uan]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UAN OCA].

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~12876312~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:012876312</ref><references group="xtra"/>
	[[Category: Thermus thermophilus]]		[[Category: Thermus thermophilus]]
	[[Category: Handa, N.]]		[[Category: Handa, N.]]
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	[[Category: Rsgi]]		[[Category: Rsgi]]
	[[Category: Structural genomic]]		[[Category: Structural genomic]]
-		+	[[Category: Unknown function]]
-	~~''Page seeded by~~ [~~http~~:~~//oca.weizmann.ac.il/oca OCA~~ ] ~~on Mon Feb 16 21:51:45 2009''~~	+