1umj - Revision history

OCA at 07:43, 25 October 2023

OCA — Wed, 25 Oct 2023 07:43:06 GMT

←Older revision		Revision as of 07:43, 25 October 2023
Line 3:		Line 3:
	<StructureSection load='1umj' size='340' side='right'caption='[[1umj]], [[Resolution\|resolution]] 1.60Å' scene=''>		<StructureSection load='1umj' size='340' side='right'caption='[[1umj]], [[Resolution\|resolution]] 1.60Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1umj]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Pyrococcus_horikoshii~~ Pyrococcus horikoshii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UMJ OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=1UMJ FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1umj]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Pyrococcus_horikoshii_OT3 Pyrococcus horikoshii OT3]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UMJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1UMJ FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=GAI:GUANIDINE'>GAI</scene>~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.6Å</td></tr>
-	<tr id='~~related~~'><td class="sblockLbl"><b>[[~~Related_structure~~\|~~Related~~:]]</b></td><td class="sblockDat"~~><div style~~=~~'overflow: auto; max-height: 3em;'~~>~~[[1j2v\|1j2v]], [[1uku\|1uku]]~~<~~/div></td></tr>~~	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GAI:GUANIDINE'>GAI</scene></td></tr>
-	~~<tr id~~='~~gene'><td class~~=~~"sblockLbl"><b>[[Gene\|Gene~~:~~]]</b~~></td>~~<td class="sblockDat">PH0992 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=70601 Pyrococcus horikoshii])~~</td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1umj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1umj OCA], [https://pdbe.org/1umj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1umj RCSB], [https://www.ebi.ac.uk/pdbsum/1umj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1umj ProSAT]</span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=1umj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1umj OCA], [~~http~~://pdbe.org/1umj PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=1umj RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/1umj PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=1umj ProSAT]</span></td></tr>	+
	</table>		</table>
	== Function ==		== Function ==
-	[~~[http~~://www.uniprot.org/uniprot/CUTA_PYRHO CUTA_PYRHO]] Involved in resistance toward heavy metals.	+	[https://www.uniprot.org/uniprot/CUTA_PYRHO CUTA_PYRHO] Involved in resistance toward heavy metals.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 38:		Line 37:
	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Pyrococcus horikoshii]]	+	[[Category: Pyrococcus horikoshii OT3]]
-	[[Category: Kumagai, I]]	+	[[Category: Kumagai I]]
-	[[Category: Sakai, N]]	+	[[Category: Sakai N]]
-	[[Category: Tanaka, I]]	+	[[Category: Tanaka I]]
-	[[Category: Tanaka, Y]]	+	[[Category: Tanaka Y]]
-	[[Category: Tsumoto, K]]	+	[[Category: Tsumoto K]]
-	[[Category: Yao, M]]	+	[[Category: Yao M]]
-	[[Category: Yasutake, Y]]	+	[[Category: Yasutake Y]]
-	~~[[Category: Copper tolerance]]~~	+
-	~~[[Category: Cuta]]~~	+
-	~~[[Category: Structural genomic]]~~	+
-	~~[[Category: Unknown function~~]]	+

OCA at 07:30, 30 December 2020

OCA — Wed, 30 Dec 2020 07:30:11 GMT

←Older revision		Revision as of 07:30, 30 December 2020
Line 1:		Line 1:

	==Crystal structure of Pyrococcus horikoshii CutA in the presence of 3M guanidine hydrochloride==		==Crystal structure of Pyrococcus horikoshii CutA in the presence of 3M guanidine hydrochloride==
-	<StructureSection load='1umj' size='340' side='right' caption='[[1umj]], [[Resolution\|resolution]] 1.60Å' scene=''>	+	<StructureSection load='1umj' size='340' side='right'caption='[[1umj]], [[Resolution\|resolution]] 1.60Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1umj]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Pyrococcus_horikoshii Pyrococcus horikoshii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UMJ OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1UMJ FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1umj]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Pyrococcus_horikoshii Pyrococcus horikoshii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UMJ OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=1UMJ FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GAI:GUANIDINE'>GAI</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GAI:GUANIDINE'>GAI</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1j2v\|1j2v]], [[1uku\|1uku]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1j2v\|1j2v]], [[1uku\|1uku]]</div></td></tr>
	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">PH0992 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=70601 Pyrococcus horikoshii])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">PH0992 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=70601 Pyrococcus horikoshii])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1umj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1umj OCA], [http://pdbe.org/1umj PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1umj RCSB], [http://www.ebi.ac.uk/pdbsum/1umj PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1umj ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=1umj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1umj OCA], [http://pdbe.org/1umj PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1umj RCSB], [http://www.ebi.ac.uk/pdbsum/1umj PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1umj ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 32:		Line 32:

	==See Also==		==See Also==
-	*[[CutA1\|CutA1]]	+	*[[CutA1 3D structures\|CutA1 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Large Structures]]
	[[Category: Pyrococcus horikoshii]]		[[Category: Pyrococcus horikoshii]]
	[[Category: Kumagai, I]]		[[Category: Kumagai, I]]

OCA at 08:14, 25 July 2018

OCA — Wed, 25 Jul 2018 08:14:01 GMT

←Older revision		Revision as of 08:14, 25 July 2018
Line 15:		Line 15:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/um/1umj_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/um/1umj_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>

OCA at 07:00, 18 October 2016

OCA — Tue, 18 Oct 2016 07:00:03 GMT

←Older revision		Revision as of 07:00, 18 October 2016
Line 1:		Line 1:
		+
	==Crystal structure of Pyrococcus horikoshii CutA in the presence of 3M guanidine hydrochloride==		==Crystal structure of Pyrococcus horikoshii CutA in the presence of 3M guanidine hydrochloride==
	<StructureSection load='1umj' size='340' side='right' caption='[[1umj]], [[Resolution\|resolution]] 1.60Å' scene=''>		<StructureSection load='1umj' size='340' side='right' caption='[[1umj]], [[Resolution\|resolution]] 1.60Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1umj]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Pyrho Pyrho~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UMJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1UMJ FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1umj]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Pyrococcus_horikoshii Pyrococcus horikoshii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UMJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1UMJ FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GAI:GUANIDINE'>GAI</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GAI:GUANIDINE'>GAI</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1j2v\|1j2v]], [[1uku\|1uku]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1j2v\|1j2v]], [[1uku\|1uku]]</td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">PH0992 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=70601 ~~PYRHO~~])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">PH0992 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=70601 Pyrococcus horikoshii])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1umj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1umj OCA], [http://pdbe.org/1umj PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1umj RCSB], [http://www.ebi.ac.uk/pdbsum/1umj PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1umj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1umj OCA], [http://pdbe.org/1umj PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1umj RCSB], [http://www.ebi.ac.uk/pdbsum/1umj PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1umj ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 36:		Line 37:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Pyrho~~]]	+	[[Category: Pyrococcus horikoshii]]
	[[Category: Kumagai, I]]		[[Category: Kumagai, I]]
	[[Category: Sakai, N]]		[[Category: Sakai, N]]

OCA at 18:36, 8 February 2016

OCA — Mon, 08 Feb 2016 18:36:08 GMT

←Older revision		Revision as of 18:36, 8 February 2016
Line 18:		Line 18:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1umj ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 14:18, 10 September 2015

OCA — Thu, 10 Sep 2015 14:18:23 GMT

←Older revision		Revision as of 14:18, 10 September 2015
Line 2:		Line 2:
	<StructureSection load='1umj' size='340' side='right' caption='[[1umj]], [[Resolution\|resolution]] 1.60Å' scene=''>		<StructureSection load='1umj' size='340' side='right' caption='[[1umj]], [[Resolution\|resolution]] 1.60Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1umj]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Pyrococcus_horikoshii_ot3 Pyrococcus horikoshii ot3~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UMJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1UMJ FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1umj]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Pyrho Pyrho]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UMJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1UMJ FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GAI:GUANIDINE'>GAI</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GAI:GUANIDINE'>GAI</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1j2v\|1j2v]], [[1uku\|1uku]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1j2v\|1j2v]], [[1uku\|1uku]]</td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">PH0992 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=70601 ~~Pyrococcus horikoshii OT3~~])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">PH0992 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=70601 PYRHO])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1umj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1umj OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1umj RCSB], [http://www.ebi.ac.uk/pdbsum/1umj PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1umj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1umj OCA], [http://pdbe.org/1umj PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1umj RCSB], [http://www.ebi.ac.uk/pdbsum/1umj PDBsum]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 28:		Line 28:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 1umj" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
Line 35:		Line 36:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Pyrococcus horikoshii ot3~~]]	+	[[Category: Pyrho]]
	[[Category: Kumagai, I]]		[[Category: Kumagai, I]]
	[[Category: Sakai, N]]		[[Category: Sakai, N]]

OCA at 01:21, 25 December 2014

OCA — Thu, 25 Dec 2014 01:21:12 GMT

←Older revision		Revision as of 01:21, 25 December 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1umj]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Pyrococcus_horikoshii_ot3 Pyrococcus horikoshii ot3]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UMJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1UMJ FirstGlance]. <br>		<table><tr><td colspan='2'>[[1umj]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Pyrococcus_horikoshii_ot3 Pyrococcus horikoshii ot3]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UMJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1UMJ FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GAI:GUANIDINE'>GAI</scene><br>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GAI:GUANIDINE'>GAI</scene></td></tr>
-	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1j2v\|1j2v]], [[1uku\|1uku]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1j2v\|1j2v]], [[1uku\|1uku]]</td></tr>
-	<tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">PH0992 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=70601 Pyrococcus horikoshii OT3])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">PH0992 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=70601 Pyrococcus horikoshii OT3])</td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1umj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1umj OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1umj RCSB], [http://www.ebi.ac.uk/pdbsum/1umj PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1umj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1umj OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1umj RCSB], [http://www.ebi.ac.uk/pdbsum/1umj PDBsum]</span></td></tr>
-	<table>	+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/CUTA_PYRHO CUTA_PYRHO]] Involved in resistance toward heavy metals.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 34:		Line 36:
	</StructureSection>		</StructureSection>
	[[Category: Pyrococcus horikoshii ot3]]		[[Category: Pyrococcus horikoshii ot3]]
-	[[Category: Kumagai, I.]]	+	[[Category: Kumagai, I]]
-	[[Category: Sakai, N.]]	+	[[Category: Sakai, N]]
-	[[Category: Tanaka, I.]]	+	[[Category: Tanaka, I]]
-	[[Category: Tanaka, Y.]]	+	[[Category: Tanaka, Y]]
-	[[Category: Tsumoto, K.]]	+	[[Category: Tsumoto, K]]
-	[[Category: Yao, M.]]	+	[[Category: Yao, M]]
-	[[Category: Yasutake, Y.]]	+	[[Category: Yasutake, Y]]
	[[Category: Copper tolerance]]		[[Category: Copper tolerance]]
	[[Category: Cuta]]		[[Category: Cuta]]
	[[Category: Structural genomic]]		[[Category: Structural genomic]]
	[[Category: Unknown function]]		[[Category: Unknown function]]

OCA at 22:54, 28 September 2014

OCA — Sun, 28 Sep 2014 22:54:23 GMT

←Older revision		Revision as of 22:54, 28 September 2014
Line 1:		Line 1:
-	[[~~Image:~~1umj.~~png~~\|~~left~~\|200px]]	+	==Crystal structure of Pyrococcus horikoshii CutA in the presence of 3M guanidine hydrochloride==
		+	<StructureSection load='1umj' size='340' side='right' caption='[[1umj]], [[Resolution\|resolution]] 1.60Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[1umj]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Pyrococcus_horikoshii_ot3 Pyrococcus horikoshii ot3]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UMJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1UMJ FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GAI:GUANIDINE'>GAI</scene><br>
		+	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1j2v\|1j2v]], [[1uku\|1uku]]</td></tr>
		+	<tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">PH0992 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=70601 Pyrococcus horikoshii OT3])</td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1umj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1umj OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1umj RCSB], [http://www.ebi.ac.uk/pdbsum/1umj PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/um/1umj_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	This study was carried out to investigate the structural perturbation of the protein's local structure by the denaturants under non-denaturing conditions. Crystal structure of CutA from an archaeon Pyrococcus horikosii (PhoCutA), a heavy-metal binding protein, was determined at 1.6-angstroms resolution in the presence of 3 M guanidine HCl (GdnHCl). Native PhoCutA has a large number of short intramolecular hydrogen bonds and salt bridges on the protein surface, of which greater than 90% of hydrogen bonds and all salt bridges were retained in 3 M GdnHCl. Hydrogen bonds that disappeared in the GdnHCl crystal structure were mainly located on the protein surface, especially around the structurally perturbed loop, suggesting interactions between peptide groups and GdnHCl. Only a few GdnH+ ions were observed in the crystal structure, although none at the surface, of the protein. Two GdnH+ ions were observed in the center of the trimeric structure, replacing water molecules, and were hydrogen bonded with Asp84 and Asp86 of each chain. The exterior loop from Tyr39 to Lys44, including Trp40-Trp41, was perturbed structurally. Decreases in temperature factors were observed in beta strand 5 and the N terminus of helix 3. These results suggest the specific bindings of GdnH+ with some acidic residues and the non-specific bindings around Trp residues and peptide groups on the protein surface and that binding of GdnHCl to the native protein is limited, resulting in local structural perturbation.

-	~~{{STRUCTURE_1umj\| PDB=1umj \| SCENE= }}~~	+	Structural evidence for guanidine-protein side chain interactions: crystal structure of CutA from Pyrococcus horikoshii in 3 M guanidine hydrochloride.,Tanaka Y, Tsumoto K, Umetsu M, Nakanishi T, Yasutake Y, Sakai N, Yao M, Tanaka I, Arakawa T, Kumagai I Biochem Biophys Res Commun. 2004 Oct 8;323(1):185-91. PMID:15351719<ref>PMID:15351719</ref>

-	~~===Crystal structure~~ of ~~Pyrococcus horikoshii CutA in~~ the ~~presence of 3M guanidine hydrochloride===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_15351719}}~~	+
-		+
-	~~==About this Structure==~~	+
-	~~[[1umj]] is a 2 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Pyrococcus_horikoshii_ot3 Pyrococcus horikoshii ot3]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=1UMJ OCA].~~	+

	==See Also==		==See Also==
	*[[CutA1\|CutA1]]		*[[CutA1\|CutA1]]
-		+	== References ==
-	==~~Reference~~==	+	<references/>
-	<~~ref group="xtra">PMID:015351719<~~/~~ref~~><~~references group="xtra"~~/>	+	__TOC__
		+	</StructureSection>
	[[Category: Pyrococcus horikoshii ot3]]		[[Category: Pyrococcus horikoshii ot3]]
	[[Category: Kumagai, I.]]		[[Category: Kumagai, I.]]

OCA: Protected "1umj" [edit=sysop:move=sysop]

OCA — Sat, 20 Oct 2012 11:05:31 GMT

Protected "1umj" [edit=sysop:move=sysop]

←Older revision

Revision as of 11:05, 20 October 2012

OCA at 11:05, 20 October 2012

OCA — Sat, 20 Oct 2012 11:05:29 GMT

←Older revision		Revision as of 11:05, 20 October 2012
Line 1:		Line 1:
-	{{Seed}}
	[[Image:1umj.png\|left\|200px]]		[[Image:1umj.png\|left\|200px]]

-	<!--
-	The line below this paragraph, containing "STRUCTURE_1umj", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_1umj\| PDB=1umj \| SCENE= }}		{{STRUCTURE_1umj\| PDB=1umj \| SCENE= }}

	===Crystal structure of Pyrococcus horikoshii CutA in the presence of 3M guanidine hydrochloride===		===Crystal structure of Pyrococcus horikoshii CutA in the presence of 3M guanidine hydrochloride===

-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_15351719}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where 15351719 is the PubMed ID number.
-	-->
	{{ABSTRACT_PUBMED_15351719}}		{{ABSTRACT_PUBMED_15351719}}

	==About this Structure==		==About this Structure==
-	~~1UMJ~~ is a 2 ~~chains~~ structure ~~of sequences~~ from [http://en.wikipedia.org/wiki/~~Pyrococcus_horikoshii~~ Pyrococcus horikoshii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UMJ OCA].	+	[[1umj]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Pyrococcus_horikoshii_ot3 Pyrococcus horikoshii ot3]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UMJ OCA].
		+
		+	==See Also==
		+	*[[CutA1\|CutA1]]

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~15351719~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:015351719</ref><references group="xtra"/>
-	[[Category: Pyrococcus horikoshii]]	+	[[Category: Pyrococcus horikoshii ot3]]
	[[Category: Kumagai, I.]]		[[Category: Kumagai, I.]]
	[[Category: Sakai, N.]]		[[Category: Sakai, N.]]
Line 35:		Line 26:
	[[Category: Cuta]]		[[Category: Cuta]]
	[[Category: Structural genomic]]		[[Category: Structural genomic]]
-		+	[[Category: Unknown function]]
-	~~''Page seeded by~~ [~~http~~:~~//oca.weizmann.ac.il/oca OCA~~ ] ~~on Tue Feb 17 01:45:37 2009''~~	+