1uqy - Revision history

OCA at 12:55, 13 December 2023

OCA — Wed, 13 Dec 2023 12:55:18 GMT

←Older revision		Revision as of 12:55, 13 December 2023
Line 3:		Line 3:
	<StructureSection load='1uqy' size='340' side='right'caption='[[1uqy]], [[Resolution\|resolution]] 1.72Å' scene=''>		<StructureSection load='1uqy' size='340' side='right'caption='[[1uqy]], [[Resolution\|resolution]] 1.72Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1uqy]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Acm_2601 Acm 2601~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UQY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1UQY FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1uqy]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Cellvibrio_mixtus Cellvibrio mixtus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UQY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1UQY FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>~~, ~~<scene name='pdbligand=XYS:XYLOPYRANOSE'>XYS</scene>, <scene name='pdbligand=XYP:BETA-D-XYLOPYRANOSE'>XYP</scene>~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.72Å</td></tr>
-	<tr id='~~related~~'><td class="sblockLbl"><b>[[~~Related_structure~~\|~~Related~~:]]</b></td><td class="sblockDat"><~~div style~~='~~overflow~~: ~~auto; max-height: 3em;~~'>~~[[1uqz\|1uqz]], [[1ur1\|1ur1]], [[1ur2\|1ur2]]~~</~~div~~><~~/td></tr>~~	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=XYP:BETA-D-XYLOPYRANOSE'>XYP</scene>, <scene name='pdbligand=XYS:XYLOPYRANOSE'>XYS</scene></td></tr>
-	~~<tr id~~='~~activity'><td class~~=~~"sblockLbl"><b>Activity~~:~~</b~~></td><~~td class~~=~~"sblockDat"><span class~~=~~'plainlinks~~'>~~[https://en.wikipedia.org/wiki/Endo-1,4-beta-xylanase Endo-1,4-beta-xylanase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.8 3.2.1.8]~~ </~~span~~></td></tr>	+
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1uqy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1uqy OCA], [https://pdbe.org/1uqy PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1uqy RCSB], [https://www.ebi.ac.uk/pdbsum/1uqy PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1uqy ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1uqy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1uqy OCA], [https://pdbe.org/1uqy PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1uqy RCSB], [https://www.ebi.ac.uk/pdbsum/1uqy PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1uqy ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/O68541_9GAMM O68541_9GAMM]
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 32:		Line 33:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Acm 2601]]~~	+	[[Category: Cellvibrio mixtus]]
-	~~[[Category: Endo-1,4-beta-xylanase~~]]	+
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Davies~~, G J~~]]	+	[[Category: Davies GJ]]
-	[[Category: Ferreira~~, L M.A~~]]	+	[[Category: Ferreira LMA]]
-	[[Category: Fontes~~, C M.G A~~]]	+	[[Category: Fontes CMGA]]
-	[[Category: Gilbert~~, H J~~]]	+	[[Category: Gilbert HJ]]
-	[[Category: Gloster~~, T M~~]]	+	[[Category: Gloster TM]]
-	[[Category: Pell, G]]	+	[[Category: Pell G]]
-	[[Category: Taylor~~, E J~~]]	+	[[Category: Taylor EJ]]
-	[[Category: Turkenburg~~, J P]]~~	+	[[Category: Turkenburg JP]]
-	~~[[Category: Family 10]]~~	+
-	~~[[Category: Glycoside hydrolase]]~~	+
-	~~[[Category: Hemicellulose]]~~	+
-	~~[[Category: Hydrolase]]~~	+
-	~~[[Category: Xylan degradation]]~~	+
-	~~[[Category: Xylanase~~]]	+

OCA at 06:16, 6 October 2021

OCA — Wed, 06 Oct 2021 06:16:27 GMT

←Older revision		Revision as of 06:16, 6 October 2021
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	<StructureSection load='1uqy' size='340' side='right'caption='[[1uqy]], [[Resolution\|resolution]] 1.72Å' scene=''>		<StructureSection load='1uqy' size='340' side='right'caption='[[1uqy]], [[Resolution\|resolution]] 1.72Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1uqy]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Acm_2601 Acm 2601]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UQY OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1UQY FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1uqy]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Acm_2601 Acm 2601]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UQY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1UQY FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=~~XYP~~:~~BETA-D-~~XYLOPYRANOSE'>~~XYP~~</scene>, <scene name='pdbligand=~~XYS~~:XYLOPYRANOSE'>~~XYS~~</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=XYS:XYLOPYRANOSE'>XYS</scene>, <scene name='pdbligand=XYP:BETA-D-XYLOPYRANOSE'>XYP</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1uqz\|1uqz]], [[1ur1\|1ur1]], [[1ur2\|1ur2]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1uqz\|1uqz]], [[1ur1\|1ur1]], [[1ur2\|1ur2]]</div></td></tr>
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://en.wikipedia.org/wiki/Endo-1,4-beta-xylanase Endo-1,4-beta-xylanase], with EC number [~~http~~://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.8 3.2.1.8] </span></td></tr>	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Endo-1,4-beta-xylanase Endo-1,4-beta-xylanase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.8 3.2.1.8] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1uqy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1uqy OCA], [~~http~~://pdbe.org/1uqy PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=1uqy RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/1uqy PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=1uqy ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1uqy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1uqy OCA], [https://pdbe.org/1uqy PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1uqy RCSB], [https://www.ebi.ac.uk/pdbsum/1uqy PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1uqy ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==

OCA at 12:57, 1 January 2020

OCA — Wed, 01 Jan 2020 12:57:14 GMT

←Older revision		Revision as of 12:57, 1 January 2020
Line 1:		Line 1:

	==Xylanase Xyn10B mutant (E262S) from Cellvibrio mixtus in complex with xylopentaose==		==Xylanase Xyn10B mutant (E262S) from Cellvibrio mixtus in complex with xylopentaose==
-	<StructureSection load='1uqy' size='340' side='right' caption='[[1uqy]], [[Resolution\|resolution]] 1.72Å' scene=''>	+	<StructureSection load='1uqy' size='340' side='right'caption='[[1uqy]], [[Resolution\|resolution]] 1.72Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1uqy]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Acm_2601 Acm 2601]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UQY OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1UQY FirstGlance]. <br>		<table><tr><td colspan='2'>[[1uqy]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Acm_2601 Acm 2601]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UQY OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1UQY FirstGlance]. <br>
Line 34:		Line 34:
	[[Category: Acm 2601]]		[[Category: Acm 2601]]
	[[Category: Endo-1,4-beta-xylanase]]		[[Category: Endo-1,4-beta-xylanase]]
		+	[[Category: Large Structures]]
	[[Category: Davies, G J]]		[[Category: Davies, G J]]
	[[Category: Ferreira, L M.A]]		[[Category: Ferreira, L M.A]]

OCA at 07:46, 28 March 2018

OCA — Wed, 28 Mar 2018 07:46:35 GMT

←Older revision		Revision as of 07:46, 28 March 2018
Line 1:		Line 1:
-	==~~XYLANASE XYN10B MUTANT~~ (E262S) ~~FROM CELLVIBRIO MIXTUS IN COMPLEX WITH XYLOPENTAOSE~~==	+
		+	==Xylanase Xyn10B mutant (E262S) from Cellvibrio mixtus in complex with xylopentaose==
	<StructureSection load='1uqy' size='340' side='right' caption='[[1uqy]], [[Resolution\|resolution]] 1.72Å' scene=''>		<StructureSection load='1uqy' size='340' side='right' caption='[[1uqy]], [[Resolution\|resolution]] 1.72Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1uqy]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Acm_2601 Acm 2601]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UQY OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1UQY FirstGlance]. <br>		<table><tr><td colspan='2'>[[1uqy]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Acm_2601 Acm 2601]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UQY OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1UQY FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=~~XYS~~:XYLOPYRANOSE'>~~XYS~~</scene>, <scene name='pdbligand=~~XYP~~:~~BETA-D-~~XYLOPYRANOSE'>~~XYP~~</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=XYP:BETA-D-XYLOPYRANOSE'>XYP</scene>, <scene name='pdbligand=XYS:XYLOPYRANOSE'>XYS</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1uqz\|1uqz]], [[1ur1\|1ur1]], [[1ur2\|1ur2]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1uqz\|1uqz]], [[1ur1\|1ur1]], [[1ur2\|1ur2]]</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Endo-1,4-beta-xylanase Endo-1,4-beta-xylanase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.8 3.2.1.8] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Endo-1,4-beta-xylanase Endo-1,4-beta-xylanase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.8 3.2.1.8] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1uqy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1uqy OCA], [http://pdbe.org/1uqy PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1uqy RCSB], [http://www.ebi.ac.uk/pdbsum/1uqy PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1uqy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1uqy OCA], [http://pdbe.org/1uqy PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1uqy RCSB], [http://www.ebi.ac.uk/pdbsum/1uqy PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1uqy ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 12:		Line 13:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/uq/1uqy_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/uq/1uqy_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>

OCA at 23:36, 9 February 2016

OCA — Tue, 09 Feb 2016 23:36:29 GMT

←Older revision		Revision as of 23:36, 9 February 2016
Line 16:		Line 16:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1uqy ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 03:10, 11 September 2015

OCA — Fri, 11 Sep 2015 03:10:46 GMT

←Older revision		Revision as of 03:10, 11 September 2015
Line 2:		Line 2:
	<StructureSection load='1uqy' size='340' side='right' caption='[[1uqy]], [[Resolution\|resolution]] 1.72Å' scene=''>		<StructureSection load='1uqy' size='340' side='right' caption='[[1uqy]], [[Resolution\|resolution]] 1.72Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1uqy]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Cellvibrio_mixtus Cellvibrio mixtus~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UQY OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1UQY FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1uqy]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Acm_2601 Acm 2601]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UQY OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1UQY FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=XYS:XYLOPYRANOSE'>XYS</scene>, <scene name='pdbligand=XYP:BETA-D-XYLOPYRANOSE'>XYP</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=XYS:XYLOPYRANOSE'>XYS</scene>, <scene name='pdbligand=XYP:BETA-D-XYLOPYRANOSE'>XYP</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1uqz\|1uqz]], [[1ur1\|1ur1]], [[1ur2\|1ur2]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1uqz\|1uqz]], [[1ur1\|1ur1]], [[1ur2\|1ur2]]</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Endo-1,4-beta-xylanase Endo-1,4-beta-xylanase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.8 3.2.1.8] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Endo-1,4-beta-xylanase Endo-1,4-beta-xylanase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.8 3.2.1.8] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1uqy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1uqy OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1uqy RCSB], [http://www.ebi.ac.uk/pdbsum/1uqy PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1uqy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1uqy OCA], [http://pdbe.org/1uqy PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1uqy RCSB], [http://www.ebi.ac.uk/pdbsum/1uqy PDBsum]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 26:		Line 26:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 1uqy" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Cellvibrio mixtus~~]]	+	[[Category: Acm 2601]]
	[[Category: Endo-1,4-beta-xylanase]]		[[Category: Endo-1,4-beta-xylanase]]
	[[Category: Davies, G J]]		[[Category: Davies, G J]]

OCA at 12:34, 6 January 2015

OCA — Tue, 06 Jan 2015 12:34:58 GMT

←Older revision		Revision as of 12:34, 6 January 2015
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1uqy]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Cellvibrio_mixtus Cellvibrio mixtus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UQY OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1UQY FirstGlance]. <br>		<table><tr><td colspan='2'>[[1uqy]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Cellvibrio_mixtus Cellvibrio mixtus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UQY OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1UQY FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=XYS:XYLOPYRANOSE'>XYS</scene>, <scene name='pdbligand=XYP:BETA-D-XYLOPYRANOSE'>XYP</scene><br>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=XYS:XYLOPYRANOSE'>XYS</scene>, <scene name='pdbligand=XYP:BETA-D-XYLOPYRANOSE'>XYP</scene></td></tr>
-	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1uqz\|1uqz]], [[1ur1\|1ur1]], [[1ur2\|1ur2]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1uqz\|1uqz]], [[1ur1\|1ur1]], [[1ur2\|1ur2]]</td></tr>
-	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Endo-1,4-beta-xylanase Endo-1,4-beta-xylanase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.8 3.2.1.8] </span></td></tr>	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Endo-1,4-beta-xylanase Endo-1,4-beta-xylanase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.8 3.2.1.8] </span></td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1uqy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1uqy OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1uqy RCSB], [http://www.ebi.ac.uk/pdbsum/1uqy PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1uqy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1uqy OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1uqy RCSB], [http://www.ebi.ac.uk/pdbsum/1uqy PDBsum]</span></td></tr>
-	<table>	+	</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 32:		Line 32:
	[[Category: Cellvibrio mixtus]]		[[Category: Cellvibrio mixtus]]
	[[Category: Endo-1,4-beta-xylanase]]		[[Category: Endo-1,4-beta-xylanase]]
-	[[Category: Davies, G J.]]	+	[[Category: Davies, G J]]
-	[[Category: Ferreira, L M.A.]]	+	[[Category: Ferreira, L M.A]]
-	[[Category: Fontes, C M.G A.]]	+	[[Category: Fontes, C M.G A]]
-	[[Category: Gilbert, H J.]]	+	[[Category: Gilbert, H J]]
-	[[Category: Gloster, T M.]]	+	[[Category: Gloster, T M]]
-	[[Category: Pell, G.]]	+	[[Category: Pell, G]]
-	[[Category: Taylor, E J.]]	+	[[Category: Taylor, E J]]
-	[[Category: Turkenburg, J P.]]	+	[[Category: Turkenburg, J P]]
	[[Category: Family 10]]		[[Category: Family 10]]
	[[Category: Glycoside hydrolase]]		[[Category: Glycoside hydrolase]]

OCA at 21:23, 29 September 2014

OCA — Mon, 29 Sep 2014 21:23:57 GMT

←Older revision		Revision as of 21:23, 29 September 2014
Line 1:		Line 1:
-	[[~~Image:~~1uqy.~~png~~\|~~left~~\|200px]]	+	==XYLANASE XYN10B MUTANT (E262S) FROM CELLVIBRIO MIXTUS IN COMPLEX WITH XYLOPENTAOSE==
		+	<StructureSection load='1uqy' size='340' side='right' caption='[[1uqy]], [[Resolution\|resolution]] 1.72Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[1uqy]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Cellvibrio_mixtus Cellvibrio mixtus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UQY OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1UQY FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=XYS:XYLOPYRANOSE'>XYS</scene>, <scene name='pdbligand=XYP:BETA-D-XYLOPYRANOSE'>XYP</scene><br>
		+	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1uqz\|1uqz]], [[1ur1\|1ur1]], [[1ur2\|1ur2]]</td></tr>
		+	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Endo-1,4-beta-xylanase Endo-1,4-beta-xylanase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.8 3.2.1.8] </span></td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1uqy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1uqy OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1uqy RCSB], [http://www.ebi.ac.uk/pdbsum/1uqy PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/uq/1uqy_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Endo-beta-1,4-xylanases (xylanases), which cleave beta-1,4 glycosidic bonds in the xylan backbone, are important components of the repertoire of enzymes that catalyze plant cell wall degradation. The mechanism by which these enzymes are able to hydrolyze a range of decorated xylans remains unclear. Here we reveal the three-dimensional structure, determined by x-ray crystallography, and the catalytic properties of the Cellvibrio mixtus enzyme Xyn10B (CmXyn10B), the most active GH10 xylanase described to date. The crystal structure of the enzyme in complex with xylopentaose reveals that at the +1 subsite the xylose moiety is sandwiched between hydrophobic residues, which is likely to mediate tighter binding than in other GH10 xylanases. The crystal structure of the xylanase in complex with a range of decorated xylooligosaccharides reveals how this enzyme is able to hydrolyze substituted xylan. Solvent exposure of the O-2 groups of xylose at the +4, +3, +1, and -3 subsites may allow accommodation of the alpha-1,2-linked 4-O-methyl-d-glucuronic acid side chain in glucuronoxylan at these locations. Furthermore, the uronic acid makes hydrogen bonds and hydrophobic interactions with the enzyme at the +1 subsite, indicating that the sugar decorations in glucuronoxylan are targeted to this proximal aglycone binding site. Accommodation of 3'-linked l-arabinofuranoside decorations is observed in the -2 subsite and could, most likely, be tolerated when bound to xylosides in -3 and +4. A notable feature of the binding mode of decorated substrates is the way in which the subsite specificities are tailored both to prevent the formation of "dead-end" reaction products and to facilitate synergy with the xylan degradation-accessory enzymes such as alpha-glucuronidase. The data described in this report and in the accompanying paper indicate that the complementarity in the binding of decorated substrates between the glycone and aglycone regions appears to be a conserved feature of GH10 xylanases.

-	~~{{STRUCTURE_1uqy\| PDB=1uqy \| SCENE= }}~~	+	The mechanisms by which family 10 glycoside hydrolases bind decorated substrates.,Pell G, Taylor EJ, Gloster TM, Turkenburg JP, Fontes CM, Ferreira LM, Nagy T, Clark SJ, Davies GJ, Gilbert HJ J Biol Chem. 2004 Mar 5;279(10):9597-605. Epub 2003 Dec 10. PMID:14668328<ref>PMID:14668328</ref>

-	~~===XYLANASE XYN10B MUTANT (E262S) FROM CELLVIBRIO MIXTUS IN COMPLEX WITH XYLOPENTAOSE===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_14668328}}~~	+	== References ==
-		+	<references/>
-	~~==About this Structure==~~	+	__TOC__
-	~~[[1uqy]] is~~ a ~~1 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Cellvibrio_mixtus Cellvibrio mixtus]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=1UQY OCA].~~	+	</StructureSection>
-		+
-	==~~Reference~~==	+
-	<~~ref group="xtra">PMID:014668328<~~/~~ref~~><~~references group="xtra"~~/>	+
	[[Category: Cellvibrio mixtus]]		[[Category: Cellvibrio mixtus]]
	[[Category: Endo-1,4-beta-xylanase]]		[[Category: Endo-1,4-beta-xylanase]]

OCA: Protected "1uqy" [edit=sysop:move=sysop]

OCA — Sat, 05 Jan 2013 12:36:36 GMT

Protected "1uqy" [edit=sysop:move=sysop]

←Older revision

Revision as of 12:36, 5 January 2013

OCA at 12:36, 5 January 2013

OCA — Sat, 05 Jan 2013 12:36:32 GMT

←Older revision		Revision as of 12:36, 5 January 2013
Line 1:		Line 1:
-	{{Seed}}
	[[Image:1uqy.png\|left\|200px]]		[[Image:1uqy.png\|left\|200px]]

-	<!--
-	The line below this paragraph, containing "STRUCTURE_1uqy", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_1uqy\| PDB=1uqy \| SCENE= }}		{{STRUCTURE_1uqy\| PDB=1uqy \| SCENE= }}

	===XYLANASE XYN10B MUTANT (E262S) FROM CELLVIBRIO MIXTUS IN COMPLEX WITH XYLOPENTAOSE===		===XYLANASE XYN10B MUTANT (E262S) FROM CELLVIBRIO MIXTUS IN COMPLEX WITH XYLOPENTAOSE===

-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_14668328}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where 14668328 is the PubMed ID number.
-	-->
	{{ABSTRACT_PUBMED_14668328}}		{{ABSTRACT_PUBMED_14668328}}

	==About this Structure==		==About this Structure==
-	~~1UQY~~ is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Cellvibrio_mixtus Cellvibrio mixtus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UQY OCA].	+	[[1uqy]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Cellvibrio_mixtus Cellvibrio mixtus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UQY OCA].

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~14668328~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:014668328</ref><references group="xtra"/>
	[[Category: Cellvibrio mixtus]]		[[Category: Cellvibrio mixtus]]
	[[Category: Endo-1,4-beta-xylanase]]		[[Category: Endo-1,4-beta-xylanase]]
Line 30:		Line 18:
	[[Category: Fontes, C M.G A.]]		[[Category: Fontes, C M.G A.]]
	[[Category: Gilbert, H J.]]		[[Category: Gilbert, H J.]]
-	[[Category: Gloster, T.]]	+	[[Category: Gloster, T M.]]
	[[Category: Pell, G.]]		[[Category: Pell, G.]]
	[[Category: Taylor, E J.]]		[[Category: Taylor, E J.]]
Line 37:		Line 25:
	[[Category: Glycoside hydrolase]]		[[Category: Glycoside hydrolase]]
	[[Category: Hemicellulose]]		[[Category: Hemicellulose]]
		+	[[Category: Hydrolase]]
	[[Category: Xylan degradation]]		[[Category: Xylan degradation]]
	[[Category: Xylanase]]		[[Category: Xylanase]]
-
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 13:39:03 2009''