1uwi - Revision history

OCA at 13:01, 13 December 2023

OCA — Wed, 13 Dec 2023 13:01:52 GMT

←Older revision		Revision as of 13:01, 13 December 2023
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	<StructureSection load='1uwi' size='340' side='right'caption='[[1uwi]], [[Resolution\|resolution]] 2.55Å' scene=''>		<StructureSection load='1uwi' size='340' side='right'caption='[[1uwi]], [[Resolution\|resolution]] 2.55Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1uwi]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Sulso Sulso~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UWI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1UWI FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1uwi]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharolobus_solfataricus_P2 Saccharolobus solfataricus P2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UWI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1UWI FirstGlance]. <br>
-	</td></tr><tr id='~~related~~'><td class="sblockLbl"><b>[[~~Related_structure~~\|~~Related~~:]]</b></td><td class="sblockDat"~~><div style='overflow: auto; max-height: 3em;'>[[1gow\|1gow]]</div></td></tr>~~	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.55Å</td></tr>
-	~~<tr~~ id~~='activity'><td class~~="~~sblockLbl~~">~~<b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Beta~~-~~galactosidase Beta-galactosidase]~~, ~~with EC number~~ [~~https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.~~2.~~1.23 3.2.1.23] </span>~~</td></tr>	+
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1uwi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1uwi OCA], [https://pdbe.org/1uwi PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1uwi RCSB], [https://www.ebi.ac.uk/pdbsum/1uwi PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1uwi ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1uwi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1uwi OCA], [https://pdbe.org/1uwi PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1uwi RCSB], [https://www.ebi.ac.uk/pdbsum/1uwi PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1uwi ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/BGAL_SACS2 BGAL_SACS2]
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Beta-galactosidase]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: ~~Sulso~~]]	+	[[Category: Saccharolobus solfataricus P2]]
-	[[Category: Isorna, P]]	+	[[Category: Isorna P]]
-	[[Category: Polaina, J]]	+	[[Category: Polaina J]]
-	[[Category: Sanz-Aparicio, J]]	+	[[Category: Sanz-Aparicio J]]
-	~~[[Category: Beta-glycosidase]]~~	+
-	~~[[Category: Glycosidase]]~~	+
-	~~[[Category: Hydrolase~~]]	+

OCA at 06:19, 6 October 2021

OCA — Wed, 06 Oct 2021 06:19:37 GMT

←Older revision		Revision as of 06:19, 6 October 2021
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	<StructureSection load='1uwi' size='340' side='right'caption='[[1uwi]], [[Resolution\|resolution]] 2.55Å' scene=''>		<StructureSection load='1uwi' size='340' side='right'caption='[[1uwi]], [[Resolution\|resolution]] 2.55Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1uwi]] is a 4 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Sulso Sulso]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UWI OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1UWI FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1uwi]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Sulso Sulso]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UWI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1UWI FirstGlance]. <br>
-	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1gow\|1gow]]</td></tr>	+	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1gow\|1gow]]</div></td></tr>
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://en.wikipedia.org/wiki/Beta-galactosidase Beta-galactosidase], with EC number [~~http~~://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.23 3.2.1.23] </span></td></tr>	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Beta-galactosidase Beta-galactosidase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.23 3.2.1.23] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1uwi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1uwi OCA], [~~http~~://pdbe.org/1uwi PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=1uwi RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/1uwi PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=1uwi ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1uwi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1uwi OCA], [https://pdbe.org/1uwi PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1uwi RCSB], [https://www.ebi.ac.uk/pdbsum/1uwi PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1uwi ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==

OCA at 13:08, 1 January 2020

OCA — Wed, 01 Jan 2020 13:08:11 GMT

←Older revision		Revision as of 13:08, 1 January 2020
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	==CRYSTAL STRUCTURE OF MUTATED BETA-GLYCOSIDASE FROM SULFOLOBUS SOLFATARICUS, WORKING AT MODERATE TEMPERATURE==		==CRYSTAL STRUCTURE OF MUTATED BETA-GLYCOSIDASE FROM SULFOLOBUS SOLFATARICUS, WORKING AT MODERATE TEMPERATURE==
-	<StructureSection load='1uwi' size='340' side='right' caption='[[1uwi]], [[Resolution\|resolution]] 2.55Å' scene=''>	+	<StructureSection load='1uwi' size='340' side='right'caption='[[1uwi]], [[Resolution\|resolution]] 2.55Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1uwi]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Sulso Sulso]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UWI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1UWI FirstGlance]. <br>		<table><tr><td colspan='2'>[[1uwi]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Sulso Sulso]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UWI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1UWI FirstGlance]. <br>
Line 29:		Line 29:

	==See Also==		==See Also==
-	*[[Galactosidase\|Galactosidase]]	+	*[[Galactosidase 3D structures\|Galactosidase 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
Line 35:		Line 35:
	</StructureSection>		</StructureSection>
	[[Category: Beta-galactosidase]]		[[Category: Beta-galactosidase]]
		+	[[Category: Large Structures]]
	[[Category: Sulso]]		[[Category: Sulso]]
	[[Category: Isorna, P]]		[[Category: Isorna, P]]

OCA at 07:58, 28 March 2018

OCA — Wed, 28 Mar 2018 07:58:27 GMT

←Older revision		Revision as of 07:58, 28 March 2018
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		+
	==CRYSTAL STRUCTURE OF MUTATED BETA-GLYCOSIDASE FROM SULFOLOBUS SOLFATARICUS, WORKING AT MODERATE TEMPERATURE==		==CRYSTAL STRUCTURE OF MUTATED BETA-GLYCOSIDASE FROM SULFOLOBUS SOLFATARICUS, WORKING AT MODERATE TEMPERATURE==
	<StructureSection load='1uwi' size='340' side='right' caption='[[1uwi]], [[Resolution\|resolution]] 2.55Å' scene=''>		<StructureSection load='1uwi' size='340' side='right' caption='[[1uwi]], [[Resolution\|resolution]] 2.55Å' scene=''>
Line 5:		Line 6:
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1gow\|1gow]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1gow\|1gow]]</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Beta-galactosidase Beta-galactosidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.23 3.2.1.23] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Beta-galactosidase Beta-galactosidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.23 3.2.1.23] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1uwi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1uwi OCA], [http://pdbe.org/1uwi PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1uwi RCSB], [http://www.ebi.ac.uk/pdbsum/1uwi PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1uwi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1uwi OCA], [http://pdbe.org/1uwi PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1uwi RCSB], [http://www.ebi.ac.uk/pdbsum/1uwi PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1uwi ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 11:		Line 12:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/uw/1uwi_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/uw/1uwi_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>

OCA at 18:56, 7 February 2016

OCA — Sun, 07 Feb 2016 18:56:04 GMT

←Older revision		Revision as of 18:56, 7 February 2016
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	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1uwi ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 04:13, 10 September 2015

OCA — Thu, 10 Sep 2015 04:13:35 GMT

←Older revision		Revision as of 04:13, 10 September 2015
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	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1gow\|1gow]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1gow\|1gow]]</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Beta-galactosidase Beta-galactosidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.23 3.2.1.23] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Beta-galactosidase Beta-galactosidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.23 3.2.1.23] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1uwi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1uwi OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1uwi RCSB], [http://www.ebi.ac.uk/pdbsum/1uwi PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1uwi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1uwi OCA], [http://pdbe.org/1uwi PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1uwi RCSB], [http://www.ebi.ac.uk/pdbsum/1uwi PDBsum]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
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	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 1uwi" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==

OCA at 12:49, 6 January 2015

OCA — Tue, 06 Jan 2015 12:49:24 GMT

←Older revision		Revision as of 12:49, 6 January 2015
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1uwi]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Sulso Sulso]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UWI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1UWI FirstGlance]. <br>		<table><tr><td colspan='2'>[[1uwi]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Sulso Sulso]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UWI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1UWI FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1gow\|1gow]]</td></tr>	+	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1gow\|1gow]]</td></tr>
-	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Beta-galactosidase Beta-galactosidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.23 3.2.1.23] </span></td></tr>	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Beta-galactosidase Beta-galactosidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.23 3.2.1.23] </span></td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1uwi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1uwi OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1uwi RCSB], [http://www.ebi.ac.uk/pdbsum/1uwi PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1uwi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1uwi OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1uwi RCSB], [http://www.ebi.ac.uk/pdbsum/1uwi PDBsum]</span></td></tr>
-	<table>	+	</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
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	[[Category: Beta-galactosidase]]		[[Category: Beta-galactosidase]]
	[[Category: Sulso]]		[[Category: Sulso]]
-	[[Category: Isorna, P.]]	+	[[Category: Isorna, P]]
-	[[Category: Polaina, J.]]	+	[[Category: Polaina, J]]
-	[[Category: Sanz-Aparicio, J.]]	+	[[Category: Sanz-Aparicio, J]]
	[[Category: Beta-glycosidase]]		[[Category: Beta-glycosidase]]
	[[Category: Glycosidase]]		[[Category: Glycosidase]]
	[[Category: Hydrolase]]		[[Category: Hydrolase]]

OCA at 06:27, 30 July 2014

OCA — Wed, 30 Jul 2014 06:27:09 GMT

←Older revision		Revision as of 06:27, 30 July 2014
Line 1:		Line 1:
-	[[~~Image:~~1uwi.~~png~~\|~~left~~\|200px]]	+	==CRYSTAL STRUCTURE OF MUTATED BETA-GLYCOSIDASE FROM SULFOLOBUS SOLFATARICUS, WORKING AT MODERATE TEMPERATURE==
		+	<StructureSection load='1uwi' size='340' side='right' caption='[[1uwi]], [[Resolution\|resolution]] 2.55Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[1uwi]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Sulso Sulso]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UWI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1UWI FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1gow\|1gow]]</td></tr>
		+	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Beta-galactosidase Beta-galactosidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.23 3.2.1.23] </span></td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1uwi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1uwi OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1uwi RCSB], [http://www.ebi.ac.uk/pdbsum/1uwi PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/uw/1uwi_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Comparison of the three-dimensional structure of hyperthermophilic and mesophilic beta-glycosidases shows differences in secondary structure composition. The enzymes from hyperthermophilic archaea have a significantly larger number of beta-strands arranged in supernumerary beta-sheets compared to mesophilic enzymes from bacteria and other organisms. Amino acid replacements designed to alter the structure of the supernumerary beta-strands were introduced by site directed mutagenesis into the sequence encoding the beta-glycosidase from Sulfolobus solfataricus. Most of the replacements caused almost complete loss of activity but some yielded enzyme variants whose activities were affected specifically at higher temperatures. Far-UV CD spectra recorded as a function of temperature for both wild type beta-glycosidase and mutant V349G, one of the mutants with reduced activity at higher temperatures, were similar, showing that the protein structure of the mutant was stable at the highest temperatures assayed. The properties of mutant V349G show a difference between thermostability (stability of the protein structure at high temperatures) and thermophilicity (optimal activity at high temperatures).

-	~~{{STRUCTURE_1uwi\| PDB=1uwi \| SCENE= }}~~	+	Comparative study and mutational analysis of distinctive structural elements of hyperthermophilic enzymes.,Leon M, Isorna P, Menendez M, Sanz-Aparicio J, Polaina J Protein J. 2007 Sep;26(6):435-44. PMID:17503162<ref>PMID:17503162</ref>

-	~~===CRYSTAL STRUCTURE OF MUTATED BETA-GLYCOSIDASE FROM SULFOLOBUS SOLFATARICUS~~, ~~WORKING AT MODERATE TEMPERATURE===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-		+
-	~~==About this Structure==~~	+
-	~~[[1uwi]] is~~ a ~~4 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Sulfolobus_solfataricus Sulfolobus solfataricus]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=1UWI OCA].~~	+

	==See Also==		==See Also==
	*[[Galactosidase\|Galactosidase]]		*[[Galactosidase\|Galactosidase]]
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
	[[Category: Beta-galactosidase]]		[[Category: Beta-galactosidase]]
-	[[Category: ~~Sulfolobus solfataricus~~]]	+	[[Category: Sulso]]
	[[Category: Isorna, P.]]		[[Category: Isorna, P.]]
	[[Category: Polaina, J.]]		[[Category: Polaina, J.]]

OCA at 07:35, 20 October 2012

OCA — Sat, 20 Oct 2012 07:35:10 GMT

←Older revision		Revision as of 07:35, 20 October 2012
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	==About this Structure==		==About this Structure==
-	[[1uwi]] is a 4 chain structure ~~of [[Galactosidase]]~~ with sequence from [http://en.wikipedia.org/wiki/Sulfolobus_solfataricus Sulfolobus solfataricus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UWI OCA].	+	[[1uwi]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Sulfolobus_solfataricus Sulfolobus solfataricus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UWI OCA].

	==See Also==		==See Also==

OCA: Protected "1uwi" [edit=sysop:move=sysop]

OCA — Wed, 25 Jul 2012 16:47:12 GMT

Protected "1uwi" [edit=sysop:move=sysop]

←Older revision

Revision as of 16:47, 25 July 2012