1v36 - Revision history

OCA at 06:23, 6 October 2021

OCA — Wed, 06 Oct 2021 06:23:44 GMT

←Older revision		Revision as of 06:23, 6 October 2021
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	<StructureSection load='1v36' size='340' side='right'caption='[[1v36]]' scene=''>		<StructureSection load='1v36' size='340' side='right'caption='[[1v36]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1V36 FirstGlance]. <br>	+	<table><tr><td colspan='2'>For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1V36 FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1v36 FirstGlance], [~~http~~://www.ebi.ac.uk/pdbsum/1v36 PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=1v36 ProSAT]</span></td></tr>	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1v36 FirstGlance], [https://www.ebi.ac.uk/pdbsum/1v36 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1v36 ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 12:52, 1 January 2020

OCA — Wed, 01 Jan 2020 12:52:02 GMT

←Older revision		Revision as of 12:52, 1 January 2020
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	==MOLECULAR MODEL OF THE PORE FORM OF ANTHRAX PROTECTIVE ANTIGEN. EXTENDING AVAILABLE BIOCHEMICAL AND CRYSTALLOGRAPHIC DATA==		==MOLECULAR MODEL OF THE PORE FORM OF ANTHRAX PROTECTIVE ANTIGEN. EXTENDING AVAILABLE BIOCHEMICAL AND CRYSTALLOGRAPHIC DATA==
-	<StructureSection load='1v36' size='340' side='right' caption='[[1v36]]' scene=''>	+	<StructureSection load='1v36' size='340' side='right'caption='[[1v36]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1V36 FirstGlance]. <br>		<table><tr><td colspan='2'>For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1V36 FirstGlance]. <br>
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	</StructureSection>		</StructureSection>
	[[Category: Theoretical Model]]		[[Category: Theoretical Model]]
		+	[[Category: Large Structures]]
	[[Category: Nguyen, T L]]		[[Category: Nguyen, T L]]

OCA at 07:41, 28 March 2018

OCA — Wed, 28 Mar 2018 07:41:35 GMT

←Older revision		Revision as of 07:41, 28 March 2018
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	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1V36 FirstGlance]. <br>		<table><tr><td colspan='2'>For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1V36 FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1v36 FirstGlance], [http://www.ebi.ac.uk/pdbsum/1v36 PDBsum]</span></td></tr>	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1v36 FirstGlance], [http://www.ebi.ac.uk/pdbsum/1v36 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1v36 ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 10:03, 11 February 2016

OCA — Thu, 11 Feb 2016 10:03:42 GMT

←Older revision		Revision as of 10:03, 11 February 2016
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		+	{{Theoretical_model}}
		+
	==MOLECULAR MODEL OF THE PORE FORM OF ANTHRAX PROTECTIVE ANTIGEN. EXTENDING AVAILABLE BIOCHEMICAL AND CRYSTALLOGRAPHIC DATA==		==MOLECULAR MODEL OF THE PORE FORM OF ANTHRAX PROTECTIVE ANTIGEN. EXTENDING AVAILABLE BIOCHEMICAL AND CRYSTALLOGRAPHIC DATA==
	<StructureSection load='1v36' size='340' side='right' caption='[[1v36]]' scene=''>		<StructureSection load='1v36' size='340' side='right' caption='[[1v36]]' scene=''>
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Theoretical Model]]
	[[Category: Nguyen, T L]]		[[Category: Nguyen, T L]]

OCA at 10:33, 11 September 2015

OCA — Fri, 11 Sep 2015 10:33:13 GMT

←Older revision		Revision as of 10:33, 11 September 2015
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	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 1v36" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>

OCA at 12:29, 6 January 2015

OCA — Tue, 06 Jan 2015 12:29:52 GMT

←Older revision		Revision as of 12:29, 6 January 2015
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	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1V36 FirstGlance]. <br>		<table><tr><td colspan='2'>For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1V36 FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1v36 FirstGlance], [http://www.ebi.ac.uk/pdbsum/1v36 PDBsum]</span></td></tr>	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1v36 FirstGlance], [http://www.ebi.ac.uk/pdbsum/1v36 PDBsum]</span></td></tr>
-	<table>	+	</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==

OCA at 19:25, 28 September 2014

OCA — Sun, 28 Sep 2014 19:25:34 GMT

←Older revision		Revision as of 19:25, 28 September 2014
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-	~~{{Theoretical_model}}~~	+	==MOLECULAR MODEL OF THE PORE FORM OF ANTHRAX PROTECTIVE ANTIGEN. EXTENDING AVAILABLE BIOCHEMICAL AND CRYSTALLOGRAPHIC DATA==
		+	<StructureSection load='1v36' size='340' side='right' caption='[[1v36]]' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1V36 FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1v36 FirstGlance], [http://www.ebi.ac.uk/pdbsum/1v36 PDBsum]</span></td></tr>
		+	<table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Although pore formation by protective antigen (PA) is critical to cell intoxication by anthrax toxin (AT), the structure of the pore form of PA (the PA63 pore) has not been determined. Hence, in this study, the PA63 pore was modeled using the X-ray structures of monomeric PA and heptameric alpha-hemolysin (alpha-HL) as templates. The PA63 pore model consists of two weakly associated domains, namely the cap and stem domains. The ring-like cap domain has a length of 80 A and an outside diameter of 120 A, while the cylinder-like stem domain has a length of 100 A and outside diameter of approximately 28 A. This provides the PA63 pore model with a length of 180 A. Based on experimental results, the channel in the PA63 pore model was built to have a minimum diameter of ~12 A, depending on side chain conformations. Because of its large size and structural complexity, the all-atom model of the PA63 pore is the end-stage construction of four separate modeling projects described herein. The final model is consistent with published experimental results, including mutational analysis and channel conductance experiments. In addition, the model was energetically and hydropathically refined to optimize molecular packing within the protomers and at the protomer-protomer interfaces. By providing atomic detail to biochemical and biophysical data, the PA63 pore model may afford new insights into the binding mode of PA on the membrane surface, the prepore-pore transition, and the mechanism of cell entry by anthrax toxin.

-	~~[[Image~~:~~1v36~~.~~png\|left\|200px]]~~	+	Three-dimensional model of the pore form of anthrax protective antigen. Structure and biological implications.,Nguyen TL J Biomol Struct Dyn. 2004 Dec;22(3):253-65. PMID:15473701<ref>PMID:15473701</ref>

-	~~{{STRUCTURE_1v36\| PDB=1v36 \| SCENE= }}~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~===MOLECULAR MODEL OF THE PORE FORM OF ANTHRAX PROTECTIVE ANTIGEN~~. ~~EXTENDING AVAILABLE BIOCHEMICAL AND CRYSTALLOGRAPHIC DATA===~~	+	== References ==
-		+	<references/>
-	~~{{ABSTRACT_PUBMED_15473701}}~~	+	__TOC__
-		+	</StructureSection>
-	==~~Reference~~==	+
-	<~~ref group="xtra">PMID:015473701<~~/~~ref~~><~~references group="xtra"~~/>	+
	[[Category: Nguyen, T L]]		[[Category: Nguyen, T L]]

OCA: Protected "1v36" [edit=sysop:move=sysop]

OCA — Sun, 21 Oct 2012 08:50:47 GMT

Protected "1v36" [edit=sysop:move=sysop]

←Older revision

Revision as of 08:50, 21 October 2012

OCA at 08:50, 21 October 2012

OCA — Sun, 21 Oct 2012 08:50:40 GMT

←Older revision		Revision as of 08:50, 21 October 2012
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	{{Theoretical_model}}		{{Theoretical_model}}
-	~~{{Seed}}~~	+
	[[Image:1v36.png\|left\|200px]]		[[Image:1v36.png\|left\|200px]]

-	<!--
-	The line below this paragraph, containing "STRUCTURE_1v36", creates the "Structure Box" on the page.
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-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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	{{STRUCTURE_1v36\| PDB=1v36 \| SCENE= }}		{{STRUCTURE_1v36\| PDB=1v36 \| SCENE= }}

	===MOLECULAR MODEL OF THE PORE FORM OF ANTHRAX PROTECTIVE ANTIGEN. EXTENDING AVAILABLE BIOCHEMICAL AND CRYSTALLOGRAPHIC DATA===		===MOLECULAR MODEL OF THE PORE FORM OF ANTHRAX PROTECTIVE ANTIGEN. EXTENDING AVAILABLE BIOCHEMICAL AND CRYSTALLOGRAPHIC DATA===

-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_15473701}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where 15473701 is the PubMed ID number.
-	-->
	{{ABSTRACT_PUBMED_15473701}}		{{ABSTRACT_PUBMED_15473701}}
-
-	==About this Structure==
-	Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1V36 OCA].

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~15473701~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:015473701</ref><references group="xtra"/>
	[[Category: Nguyen, T L]]		[[Category: Nguyen, T L]]
-
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Apr 8 07:06:35 2010''

OCA at 04:06, 8 April 2010

OCA — Thu, 08 Apr 2010 04:06:36 GMT

←Older revision		Revision as of 04:06, 8 April 2010
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-	~~'''Theoretical Model'''~~	+	{{Theoretical_model}}
		+	{{Seed}}
		+	[[Image:1v36.png\|left\|200px]]

-	The ~~entry 1V36 is a Theoretical Model titled 'Molecular model of~~ the ~~pore form of anthrax protective antigen~~. ~~Extending available biochemical and crystallographic data'~~.	+	<!--
		+	The line below this paragraph, containing "STRUCTURE_1v36", creates the "Structure Box" on the page.
		+	You may change the PDB parameter (which sets the PDB file loaded into the applet)
		+	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
		+	or leave the SCENE parameter empty for the default display.
		+	-->
		+	{{STRUCTURE_1v36\| PDB=1v36 \| SCENE= }}

-	~~[[Category:Theoretical Model]]~~	+	===MOLECULAR MODEL OF THE PORE FORM OF ANTHRAX PROTECTIVE ANTIGEN. EXTENDING AVAILABLE BIOCHEMICAL AND CRYSTALLOGRAPHIC DATA===


-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on ~~Wed Jul 30 09~~:54:~~15 2008~~''	+	<!--
		+	The line below this paragraph, {{ABSTRACT_PUBMED_15473701}}, adds the Publication Abstract to the page
		+	(as it appears on PubMed at http://www.pubmed.gov), where 15473701 is the PubMed ID number.
		+	-->
		+	{{ABSTRACT_PUBMED_15473701}}
		+
		+	==About this Structure==
		+	Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1V36 OCA].
		+
		+	==Reference==
		+	<ref group="xtra">PMID:15473701</ref><references group="xtra"/>
		+	[[Category: Nguyen, T L]]
		+
		+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Apr 8 07:06:35 2010''