1v3d - Revision history

OCA at 07:44, 25 October 2023

OCA — Wed, 25 Oct 2023 07:44:06 GMT

←Older revision		Revision as of 07:44, 25 October 2023
Line 3:		Line 3:
	<StructureSection load='1v3d' size='340' side='right'caption='[[1v3d]], [[Resolution\|resolution]] 2.28Å' scene=''>		<StructureSection load='1v3d' size='340' side='right'caption='[[1v3d]], [[Resolution\|resolution]] 2.28Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1v3d]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Hpiv-3 Hpiv-~~3]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1V3D OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1V3D FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1v3d]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Human_respirovirus_3 Human respirovirus 3]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1V3D OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1V3D FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=DAN:2-DEOXY-2,3-DEHYDRO-N-ACETYL-NEURAMINIC+ACID'>DAN</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene~~></td></tr>~~	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.28Å</td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1v2i\|1v2i]], [[1v3b\|1v3b]], [[1v3c\|1v3c]], [[1v3e\|1v3e]]</div></td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=DAN:2-DEOXY-2,3-DEHYDRO-N-ACETYL-NEURAMINIC+ACID'>DAN</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Exo-alpha-sialidase Exo-alpha-sialidase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.18 3.2.1.18] </span></td></tr>	+
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1v3d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1v3d OCA], [https://pdbe.org/1v3d PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1v3d RCSB], [https://www.ebi.ac.uk/pdbsum/1v3d PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1v3d ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1v3d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1v3d OCA], [https://pdbe.org/1v3d PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1v3d RCSB], [https://www.ebi.ac.uk/pdbsum/1v3d PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1v3d ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/Q6WJ03_9MONO Q6WJ03_9MONO] Attaches the virus to sialic acid-containing cell receptors and thereby initiating infection. Binding of HN protein to the receptor induces a conformational change that allows the F protein to trigger virion/cell membranes fusion.[ARBA:ARBA00025476]
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Exo-alpha-sialidase]]~~	+	[[Category: Human respirovirus 3]]
-	~~[[Category: Hpiv-~~3]]	+
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Borg~~, N A~~]]	+	[[Category: Borg NA]]
-	[[Category: Colman~~, P M~~]]	+	[[Category: Colman PM]]
-	[[Category: Epa~~, V C~~]]	+	[[Category: Epa VC]]
-	[[Category: Lawrence~~, M C~~]]	+	[[Category: Lawrence MC]]
-	[[Category: McKimm-Breschkin~~, J L~~]]	+	[[Category: McKimm-Breschkin JL]]
-	[[Category: Pilling~~, P A~~]]	+	[[Category: Pilling PA]]
-	[[Category: Streltsov~~, V A~~]]	+	[[Category: Streltsov VA]]
-	[[Category: Varghese~~, J N]]~~	+	[[Category: Varghese JN]]
-	~~[[Category: Hexagonal]]~~	+
-	~~[[Category: Hydrolase]]~~	+
-	~~[[Category: Native+neu5ac2en]]~~	+
-	~~[[Category: Piv3 hn~~]]	+

OCA at 06:23, 6 October 2021

OCA — Wed, 06 Oct 2021 06:23:55 GMT

←Older revision		Revision as of 06:23, 6 October 2021
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	<StructureSection load='1v3d' size='340' side='right'caption='[[1v3d]], [[Resolution\|resolution]] 2.28Å' scene=''>		<StructureSection load='1v3d' size='340' side='right'caption='[[1v3d]], [[Resolution\|resolution]] 2.28Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1v3d]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Hpiv-3 Hpiv-3]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1V3D OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1V3D FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1v3d]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Hpiv-3 Hpiv-3]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1V3D OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1V3D FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=DAN:2-DEOXY-2,3-DEHYDRO-N-ACETYL-NEURAMINIC+ACID'>DAN</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG~~</scene>, <scene name='pdbligand=NDG:2-(ACETYLAMINO)-2-DEOXY-A-D-GLUCOPYRANOSE'>NDG~~</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=DAN:2-DEOXY-2,3-DEHYDRO-N-ACETYL-NEURAMINIC+ACID'>DAN</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1v2i\|1v2i]], [[1v3b\|1v3b]], [[1v3c\|1v3c]], [[1v3e\|1v3e]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1v2i\|1v2i]], [[1v3b\|1v3b]], [[1v3c\|1v3c]], [[1v3e\|1v3e]]</div></td></tr>
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://en.wikipedia.org/wiki/Exo-alpha-sialidase Exo-alpha-sialidase], with EC number [~~http~~://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.18 3.2.1.18] </span></td></tr>	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Exo-alpha-sialidase Exo-alpha-sialidase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.18 3.2.1.18] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1v3d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1v3d OCA], [~~http~~://pdbe.org/1v3d PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=1v3d RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/1v3d PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=1v3d ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1v3d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1v3d OCA], [https://pdbe.org/1v3d PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1v3d RCSB], [https://www.ebi.ac.uk/pdbsum/1v3d PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1v3d ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==

OCA at 13:07, 1 January 2020

OCA — Wed, 01 Jan 2020 13:07:04 GMT

←Older revision		Revision as of 13:07, 1 January 2020
Line 1:		Line 1:

	==Structure of the hemagglutinin-neuraminidase from human parainfluenza virus type III: complex with NEU5AC2EN==		==Structure of the hemagglutinin-neuraminidase from human parainfluenza virus type III: complex with NEU5AC2EN==
-	<StructureSection load='1v3d' size='340' side='right' caption='[[1v3d]], [[Resolution\|resolution]] 2.28Å' scene=''>	+	<StructureSection load='1v3d' size='340' side='right'caption='[[1v3d]], [[Resolution\|resolution]] 2.28Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1v3d]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Hpiv-3 Hpiv-3]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1V3D OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1V3D FirstGlance]. <br>		<table><tr><td colspan='2'>[[1v3d]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Hpiv-3 Hpiv-3]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1V3D OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1V3D FirstGlance]. <br>
Line 30:		Line 30:

	==See Also==		==See Also==
-	*[[Hemagglutinin\|Hemagglutinin]]	+	*[[Hemagglutinin 3D structures\|Hemagglutinin 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
Line 37:		Line 37:
	[[Category: Exo-alpha-sialidase]]		[[Category: Exo-alpha-sialidase]]
	[[Category: Hpiv-3]]		[[Category: Hpiv-3]]
		+	[[Category: Large Structures]]
	[[Category: Borg, N A]]		[[Category: Borg, N A]]
	[[Category: Colman, P M]]		[[Category: Colman, P M]]

OCA at 07:57, 28 March 2018

OCA — Wed, 28 Mar 2018 07:57:19 GMT

OCA at 07:54, 8 February 2016

OCA — Mon, 08 Feb 2016 07:54:51 GMT

←Older revision		Revision as of 07:54, 8 February 2016
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	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1v3d ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 09:27, 10 September 2015

OCA — Thu, 10 Sep 2015 09:27:27 GMT

←Older revision		Revision as of 09:27, 10 September 2015
Line 2:		Line 2:
	<StructureSection load='1v3d' size='340' side='right' caption='[[1v3d]], [[Resolution\|resolution]] 2.28Å' scene=''>		<StructureSection load='1v3d' size='340' side='right' caption='[[1v3d]], [[Resolution\|resolution]] 2.28Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1v3d]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Human_parainfluenza_virus_3 Human parainfluenza virus~~ 3]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1V3D OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1V3D FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1v3d]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Hpiv-3 Hpiv-3]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1V3D OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1V3D FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=DAN:2-DEOXY-2,3-DEHYDRO-N-ACETYL-NEURAMINIC+ACID'>DAN</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=NDG:2-(ACETYLAMINO)-2-DEOXY-A-D-GLUCOPYRANOSE'>NDG</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=DAN:2-DEOXY-2,3-DEHYDRO-N-ACETYL-NEURAMINIC+ACID'>DAN</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=NDG:2-(ACETYLAMINO)-2-DEOXY-A-D-GLUCOPYRANOSE'>NDG</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1v2i\|1v2i]], [[1v3b\|1v3b]], [[1v3c\|1v3c]], [[1v3e\|1v3e]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1v2i\|1v2i]], [[1v3b\|1v3b]], [[1v3c\|1v3c]], [[1v3e\|1v3e]]</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Exo-alpha-sialidase Exo-alpha-sialidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.18 3.2.1.18] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Exo-alpha-sialidase Exo-alpha-sialidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.18 3.2.1.18] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1v3d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1v3d OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1v3d RCSB], [http://www.ebi.ac.uk/pdbsum/1v3d PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1v3d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1v3d OCA], [http://pdbe.org/1v3d PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1v3d RCSB], [http://www.ebi.ac.uk/pdbsum/1v3d PDBsum]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 26:		Line 26:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 1v3d" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
Line 34:		Line 35:
	</StructureSection>		</StructureSection>
	[[Category: Exo-alpha-sialidase]]		[[Category: Exo-alpha-sialidase]]
-	[[Category: ~~Human parainfluenza virus~~ 3]]	+	[[Category: Hpiv-3]]
	[[Category: Borg, N A]]		[[Category: Borg, N A]]
	[[Category: Colman, P M]]		[[Category: Colman, P M]]

OCA at 13:43, 6 January 2015

OCA — Tue, 06 Jan 2015 13:43:34 GMT

←Older revision		Revision as of 13:43, 6 January 2015
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1v3d]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human_parainfluenza_virus_3 Human parainfluenza virus 3]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1V3D OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1V3D FirstGlance]. <br>		<table><tr><td colspan='2'>[[1v3d]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human_parainfluenza_virus_3 Human parainfluenza virus 3]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1V3D OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1V3D FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=DAN:2-DEOXY-2,3-DEHYDRO-N-ACETYL-NEURAMINIC+ACID'>DAN</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=NDG:2-(ACETYLAMINO)-2-DEOXY-A-D-GLUCOPYRANOSE'>NDG</scene><br>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=DAN:2-DEOXY-2,3-DEHYDRO-N-ACETYL-NEURAMINIC+ACID'>DAN</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=NDG:2-(ACETYLAMINO)-2-DEOXY-A-D-GLUCOPYRANOSE'>NDG</scene></td></tr>
-	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1v2i\|1v2i]], [[1v3b\|1v3b]], [[1v3c\|1v3c]], [[1v3e\|1v3e]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1v2i\|1v2i]], [[1v3b\|1v3b]], [[1v3c\|1v3c]], [[1v3e\|1v3e]]</td></tr>
-	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Exo-alpha-sialidase Exo-alpha-sialidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.18 3.2.1.18] </span></td></tr>	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Exo-alpha-sialidase Exo-alpha-sialidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.18 3.2.1.18] </span></td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1v3d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1v3d OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1v3d RCSB], [http://www.ebi.ac.uk/pdbsum/1v3d PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1v3d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1v3d OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1v3d RCSB], [http://www.ebi.ac.uk/pdbsum/1v3d PDBsum]</span></td></tr>
-	<table>	+	</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 35:		Line 35:
	[[Category: Exo-alpha-sialidase]]		[[Category: Exo-alpha-sialidase]]
	[[Category: Human parainfluenza virus 3]]		[[Category: Human parainfluenza virus 3]]
-	[[Category: Borg, N A.]]	+	[[Category: Borg, N A]]
-	[[Category: Colman, P M.]]	+	[[Category: Colman, P M]]
-	[[Category: Epa, V C.]]	+	[[Category: Epa, V C]]
-	[[Category: Lawrence, M C.]]	+	[[Category: Lawrence, M C]]
-	[[Category: McKimm-Breschkin, J L.]]	+	[[Category: McKimm-Breschkin, J L]]
-	[[Category: Pilling, P A.]]	+	[[Category: Pilling, P A]]
-	[[Category: Streltsov, V A.]]	+	[[Category: Streltsov, V A]]
-	[[Category: Varghese, J N.]]	+	[[Category: Varghese, J N]]
	[[Category: Hexagonal]]		[[Category: Hexagonal]]
	[[Category: Hydrolase]]		[[Category: Hydrolase]]
	[[Category: Native+neu5ac2en]]		[[Category: Native+neu5ac2en]]
	[[Category: Piv3 hn]]		[[Category: Piv3 hn]]

OCA at 21:56, 29 September 2014

OCA — Mon, 29 Sep 2014 21:56:07 GMT

←Older revision		Revision as of 21:56, 29 September 2014
Line 1:		Line 1:
-	~~{{STRUCTURE_1v3d\| PDB=1v3d \| SCENE= }}~~	+	==Structure of the hemagglutinin-neuraminidase from human parainfluenza virus type III: complex with NEU5AC2EN==
-	===Structure of the hemagglutinin-neuraminidase from human parainfluenza virus type III: complex with NEU5AC2EN===	+	<StructureSection load='1v3d' size='340' side='right' caption='[[1v3d]], [[Resolution\|resolution]] 2.28Å' scene=''>
-	~~{{ABSTRACT_PUBMED_14729348}}~~	+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[1v3d]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human_parainfluenza_virus_3 Human parainfluenza virus 3]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1V3D OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1V3D FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=DAN:2-DEOXY-2,3-DEHYDRO-N-ACETYL-NEURAMINIC+ACID'>DAN</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=NDG:2-(ACETYLAMINO)-2-DEOXY-A-D-GLUCOPYRANOSE'>NDG</scene><br>
		+	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1v2i\|1v2i]], [[1v3b\|1v3b]], [[1v3c\|1v3c]], [[1v3e\|1v3e]]</td></tr>
		+	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Exo-alpha-sialidase Exo-alpha-sialidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.18 3.2.1.18] </span></td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1v3d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1v3d OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1v3d RCSB], [http://www.ebi.ac.uk/pdbsum/1v3d PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/v3/1v3d_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	The three-dimensional structure of the haemagglutinin-neuraminidase (HN) from a human parainfluenza virus is described at ca 2.0 A resolution, both in native form and in complex with three substrate analogues. In support of earlier work on the structure of the homologous protein from the avian pathogen Newcastle disease virus (NDV), we observe a dimer of beta-propellers and find no evidence for spatially separated sites performing the receptor-binding and neuraminidase functions of the protein. As with the NDV HN, the active site of the HN of parainfluenza viruses is structurally flexible, suggesting that it may be able to switch between a receptor-binding state and a catalytic state. However, in contrast to the NDV structures, we observe no ligand-induced structural changes that extend beyond the active site and modify the dimer interface.

-	~~==About this~~ Structure==	+	Structure of the haemagglutinin-neuraminidase from human parainfluenza virus type III.,Lawrence MC, Borg NA, Streltsov VA, Pilling PA, Epa VC, Varghese JN, McKimm-Breschkin JL, Colman PM J Mol Biol. 2004 Jan 30;335(5):1343-57. PMID:14729348<ref>PMID:14729348</ref>
-	~~[[1v3d]] is a 2 chain structure with sequence~~ from ~~[http://en.wikipedia.org/wiki/Human_parainfluenza_virus_3 Human~~ parainfluenza virus 3]. ~~Full crystallographic information is available from [http~~://~~oca~~.~~weizmann~~.ac.il/~~oca-bin/ocashort?id=1V3D OCA].~~	+
		+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>

	==See Also==		==See Also==
	*[[Hemagglutinin\|Hemagglutinin]]		*[[Hemagglutinin\|Hemagglutinin]]
-		+	== References ==
-	==~~Reference~~==	+	<references/>
-	<~~ref group="xtra">PMID:014729348<~~/~~ref~~><~~references group="xtra"~~/>	+	__TOC__
		+	</StructureSection>
	[[Category: Exo-alpha-sialidase]]		[[Category: Exo-alpha-sialidase]]
	[[Category: Human parainfluenza virus 3]]		[[Category: Human parainfluenza virus 3]]

OCA at 11:01, 11 March 2013

OCA — Mon, 11 Mar 2013 11:01:47 GMT

←Older revision		Revision as of 11:01, 11 March 2013
Line 1:		Line 1:
-	[[Image:1v3d.png\|left\|200px]]
-
	{{STRUCTURE_1v3d\| PDB=1v3d \| SCENE= }}		{{STRUCTURE_1v3d\| PDB=1v3d \| SCENE= }}
-
	===Structure of the hemagglutinin-neuraminidase from human parainfluenza virus type III: complex with NEU5AC2EN===		===Structure of the hemagglutinin-neuraminidase from human parainfluenza virus type III: complex with NEU5AC2EN===
-
	{{ABSTRACT_PUBMED_14729348}}		{{ABSTRACT_PUBMED_14729348}}

OCA at 09:27, 20 October 2012

OCA — Sat, 20 Oct 2012 09:27:58 GMT

←Older revision		Revision as of 09:27, 20 October 2012
Line 8:		Line 8:

	==About this Structure==		==About this Structure==
-	[[1v3d]] is a 2 chain structure ~~of [[Hemagglutinin]]~~ with sequence from [http://en.wikipedia.org/wiki/Human_parainfluenza_virus_3 Human parainfluenza virus 3]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1V3D OCA].	+	[[1v3d]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human_parainfluenza_virus_3 Human parainfluenza virus 3]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1V3D OCA].

	==See Also==		==See Also==

←Older revision		Revision as of 07:57, 28 March 2018
Line 1:		Line 1:
		+
	==Structure of the hemagglutinin-neuraminidase from human parainfluenza virus type III: complex with NEU5AC2EN==		==Structure of the hemagglutinin-neuraminidase from human parainfluenza virus type III: complex with NEU5AC2EN==
	<StructureSection load='1v3d' size='340' side='right' caption='[[1v3d]], [[Resolution\|resolution]] 2.28Å' scene=''>		<StructureSection load='1v3d' size='340' side='right' caption='[[1v3d]], [[Resolution\|resolution]] 2.28Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1v3d]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Hpiv-3 Hpiv-3]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1V3D OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1V3D FirstGlance]. <br>		<table><tr><td colspan='2'>[[1v3d]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Hpiv-3 Hpiv-3]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1V3D OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1V3D FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=DAN:2-DEOXY-2,3-DEHYDRO-N-ACETYL-NEURAMINIC+ACID'>DAN</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG~~</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4~~</scene>, <scene name='pdbligand=NDG:2-(ACETYLAMINO)-2-DEOXY-A-D-GLUCOPYRANOSE'>NDG</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=DAN:2-DEOXY-2,3-DEHYDRO-N-ACETYL-NEURAMINIC+ACID'>DAN</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=NDG:2-(ACETYLAMINO)-2-DEOXY-A-D-GLUCOPYRANOSE'>NDG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1v2i\|1v2i]], [[1v3b\|1v3b]], [[1v3c\|1v3c]], [[1v3e\|1v3e]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1v2i\|1v2i]], [[1v3b\|1v3b]], [[1v3c\|1v3c]], [[1v3e\|1v3e]]</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Exo-alpha-sialidase Exo-alpha-sialidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.18 3.2.1.18] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Exo-alpha-sialidase Exo-alpha-sialidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.18 3.2.1.18] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1v3d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1v3d OCA], [http://pdbe.org/1v3d PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1v3d RCSB], [http://www.ebi.ac.uk/pdbsum/1v3d PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1v3d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1v3d OCA], [http://pdbe.org/1v3d PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1v3d RCSB], [http://www.ebi.ac.uk/pdbsum/1v3d PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1v3d ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 12:		Line 13:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/v3/1v3d_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/v3/1v3d_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>