1v92 - Revision history

OCA at 23:59, 27 December 2023

OCA — Wed, 27 Dec 2023 23:59:54 GMT

←Older revision		Revision as of 23:59, 27 December 2023
Line 1:		Line 1:

	==Solution structure of the UBA domain from p47, a major cofactor of the AAA ATPase p97==		==Solution structure of the UBA domain from p47, a major cofactor of the AAA ATPase p97==
-	<StructureSection load='1v92' size='340' side='right'caption='[[1v92~~]], [[NMR_Ensembles_of_Models \| 10 NMR models~~]]' scene=''>	+	<StructureSection load='1v92' size='340' side='right'caption='[[1v92]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1v92]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Buffalo_rat Buffalo rat~~]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1V92 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1V92 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1v92]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1V92 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1V92 FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1v92 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1v92 OCA], [https://pdbe.org/1v92 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1v92 RCSB], [https://www.ebi.ac.uk/pdbsum/1v92 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1v92 ProSAT]</span></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1v92 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1v92 OCA], [https://pdbe.org/1v92 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1v92 RCSB], [https://www.ebi.ac.uk/pdbsum/1v92 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1v92 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[https://www.uniprot.org/uniprot/NSF1C_RAT NSF1C_RAT]] Reduces the ATPase activity of VCP. Necessary for the fragmentation of Golgi stacks during mitosis and for VCP-mediated reassembly of Golgi stacks after mitosis. May play a role in VCP-mediated formation of transitional endoplasmic reticulum (tER).<ref>PMID:9214505</ref> <ref>PMID:9824302</ref> <ref>PMID:10930451</ref> <ref>PMID:12411482</ref>	+	[https://www.uniprot.org/uniprot/NSF1C_RAT NSF1C_RAT] Reduces the ATPase activity of VCP. Necessary for the fragmentation of Golgi stacks during mitosis and for VCP-mediated reassembly of Golgi stacks after mitosis. May play a role in VCP-mediated formation of transitional endoplasmic reticulum (tER).<ref>PMID:9214505</ref> <ref>PMID:9824302</ref> <ref>PMID:10930451</ref> <ref>PMID:12411482</ref>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 31:		Line 32:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Buffalo rat]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Dreveny, I]]	+	[[Category: Rattus norvegicus]]
-	[[Category: Freemont, P]]	+	[[Category: Dreveny I]]
-	[[Category: Keetch, C]]	+	[[Category: Freemont P]]
-	[[Category: Kondo, H]]	+	[[Category: Keetch C]]
-	[[Category: Matthews, S]]	+	[[Category: Kondo H]]
-	[[Category: Mckeown, C]]	+	[[Category: Matthews S]]
-	[[Category: Robinson, C]]	+	[[Category: Mckeown C]]
-	[[Category: Simpson, P]]	+	[[Category: Robinson C]]
-	[[Category: Uchiyama, K]]	+	[[Category: Simpson P]]
-	[[Category: Wallis, R]]	+	[[Category: Uchiyama K]]
-	[[Category: Yuan, X]]	+	[[Category: Wallis R]]
-	[[Category: Zhang, X]]	+	[[Category: Yuan X]]
-	~~[[Category: 3-helix bundle]]~~	+	[[Category: Zhang X]]
-	~~[[Category: Recombination~~]]	+

OCA at 06:28, 6 October 2021

OCA — Wed, 06 Oct 2021 06:28:02 GMT

←Older revision		Revision as of 06:28, 6 October 2021
Line 3:		Line 3:
	<StructureSection load='1v92' size='340' side='right'caption='[[1v92]], [[NMR_Ensembles_of_Models \| 10 NMR models]]' scene=''>		<StructureSection load='1v92' size='340' side='right'caption='[[1v92]], [[NMR_Ensembles_of_Models \| 10 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1v92]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Buffalo_rat Buffalo rat]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1V92 OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1V92 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1v92]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Buffalo_rat Buffalo rat]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1V92 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1V92 FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1v92 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1v92 OCA], [~~http~~://pdbe.org/1v92 PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=1v92 RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/1v92 PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=1v92 ProSAT]</span></td></tr>	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1v92 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1v92 OCA], [https://pdbe.org/1v92 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1v92 RCSB], [https://www.ebi.ac.uk/pdbsum/1v92 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1v92 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[~~http~~://www.uniprot.org/uniprot/NSF1C_RAT NSF1C_RAT]] Reduces the ATPase activity of VCP. Necessary for the fragmentation of Golgi stacks during mitosis and for VCP-mediated reassembly of Golgi stacks after mitosis. May play a role in VCP-mediated formation of transitional endoplasmic reticulum (tER).<ref>PMID:9214505</ref> <ref>PMID:9824302</ref> <ref>PMID:10930451</ref> <ref>PMID:12411482</ref>	+	[[https://www.uniprot.org/uniprot/NSF1C_RAT NSF1C_RAT]] Reduces the ATPase activity of VCP. Necessary for the fragmentation of Golgi stacks during mitosis and for VCP-mediated reassembly of Golgi stacks after mitosis. May play a role in VCP-mediated formation of transitional endoplasmic reticulum (tER).<ref>PMID:9214505</ref> <ref>PMID:9824302</ref> <ref>PMID:10930451</ref> <ref>PMID:12411482</ref>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]

OCA at 13:03, 1 January 2020

OCA — Wed, 01 Jan 2020 13:03:39 GMT

←Older revision		Revision as of 13:03, 1 January 2020
Line 1:		Line 1:

	==Solution structure of the UBA domain from p47, a major cofactor of the AAA ATPase p97==		==Solution structure of the UBA domain from p47, a major cofactor of the AAA ATPase p97==
-	<StructureSection load='1v92' size='340' side='right' caption='[[1v92]], [[NMR_Ensembles_of_Models \| 10 NMR models]]' scene=''>	+	<StructureSection load='1v92' size='340' side='right'caption='[[1v92]], [[NMR_Ensembles_of_Models \| 10 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1v92]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Buffalo_rat Buffalo rat]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1V92 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1V92 FirstGlance]. <br>		<table><tr><td colspan='2'>[[1v92]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Buffalo_rat Buffalo rat]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1V92 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1V92 FirstGlance]. <br>
Line 32:		Line 32:
	</StructureSection>		</StructureSection>
	[[Category: Buffalo rat]]		[[Category: Buffalo rat]]
		+	[[Category: Large Structures]]
	[[Category: Dreveny, I]]		[[Category: Dreveny, I]]
	[[Category: Freemont, P]]		[[Category: Freemont, P]]

OCA at 07:52, 28 March 2018

OCA — Wed, 28 Mar 2018 07:52:35 GMT

←Older revision		Revision as of 07:52, 28 March 2018
Line 1:		Line 1:
		+
	==Solution structure of the UBA domain from p47, a major cofactor of the AAA ATPase p97==		==Solution structure of the UBA domain from p47, a major cofactor of the AAA ATPase p97==
	<StructureSection load='1v92' size='340' side='right' caption='[[1v92]], [[NMR_Ensembles_of_Models \| 10 NMR models]]' scene=''>		<StructureSection load='1v92' size='340' side='right' caption='[[1v92]], [[NMR_Ensembles_of_Models \| 10 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1v92]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Buffalo_rat Buffalo rat]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1V92 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1V92 FirstGlance]. <br>		<table><tr><td colspan='2'>[[1v92]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Buffalo_rat Buffalo rat]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1V92 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1V92 FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1v92 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1v92 OCA], [http://pdbe.org/1v92 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1v92 RCSB], [http://www.ebi.ac.uk/pdbsum/1v92 PDBsum]</span></td></tr>	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1v92 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1v92 OCA], [http://pdbe.org/1v92 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1v92 RCSB], [http://www.ebi.ac.uk/pdbsum/1v92 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1v92 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 11:		Line 12:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/v9/1v92_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/v9/1v92_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>

OCA at 14:54, 8 February 2016

OCA — Mon, 08 Feb 2016 14:54:43 GMT

←Older revision		Revision as of 14:54, 8 February 2016
Line 15:		Line 15:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1v92 ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 12:41, 10 September 2015

OCA — Thu, 10 Sep 2015 12:41:21 GMT

←Older revision		Revision as of 12:41, 10 September 2015
Line 2:		Line 2:
	<StructureSection load='1v92' size='340' side='right' caption='[[1v92]], [[NMR_Ensembles_of_Models \| 10 NMR models]]' scene=''>		<StructureSection load='1v92' size='340' side='right' caption='[[1v92]], [[NMR_Ensembles_of_Models \| 10 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1v92]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Rattus_norvegicus Rattus norvegicus~~]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1V92 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1V92 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1v92]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Buffalo_rat Buffalo rat]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1V92 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1V92 FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1v92 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1v92 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1v92 RCSB], [http://www.ebi.ac.uk/pdbsum/1v92 PDBsum]</span></td></tr>	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1v92 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1v92 OCA], [http://pdbe.org/1v92 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1v92 RCSB], [http://www.ebi.ac.uk/pdbsum/1v92 PDBsum]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 25:		Line 25:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 1v92" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Rattus norvegicus~~]]	+	[[Category: Buffalo rat]]
	[[Category: Dreveny, I]]		[[Category: Dreveny, I]]
	[[Category: Freemont, P]]		[[Category: Freemont, P]]

OCA at 00:10, 25 December 2014

OCA — Thu, 25 Dec 2014 00:10:05 GMT

←Older revision		Revision as of 00:10, 25 December 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1v92]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1V92 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1V92 FirstGlance]. <br>		<table><tr><td colspan='2'>[[1v92]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1V92 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1V92 FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1v92 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1v92 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1v92 RCSB], [http://www.ebi.ac.uk/pdbsum/1v92 PDBsum]</span></td></tr>	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1v92 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1v92 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1v92 RCSB], [http://www.ebi.ac.uk/pdbsum/1v92 PDBsum]</span></td></tr>
-	<table>	+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/NSF1C_RAT NSF1C_RAT]] Reduces the ATPase activity of VCP. Necessary for the fragmentation of Golgi stacks during mitosis and for VCP-mediated reassembly of Golgi stacks after mitosis. May play a role in VCP-mediated formation of transitional endoplasmic reticulum (tER).<ref>PMID:9214505</ref> <ref>PMID:9824302</ref> <ref>PMID:10930451</ref> <ref>PMID:12411482</ref>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 28:		Line 30:
	</StructureSection>		</StructureSection>
	[[Category: Rattus norvegicus]]		[[Category: Rattus norvegicus]]
-	[[Category: Dreveny, I.]]	+	[[Category: Dreveny, I]]
-	[[Category: Freemont, P.]]	+	[[Category: Freemont, P]]
-	[[Category: Keetch, C.]]	+	[[Category: Keetch, C]]
-	[[Category: Kondo, H.]]	+	[[Category: Kondo, H]]
-	[[Category: Matthews, S.]]	+	[[Category: Matthews, S]]
-	[[Category: Mckeown, C.]]	+	[[Category: Mckeown, C]]
-	[[Category: Robinson, C.]]	+	[[Category: Robinson, C]]
-	[[Category: Simpson, P.]]	+	[[Category: Simpson, P]]
-	[[Category: Uchiyama, K.]]	+	[[Category: Uchiyama, K]]
-	[[Category: Wallis, R.]]	+	[[Category: Wallis, R]]
-	[[Category: Yuan, X.]]	+	[[Category: Yuan, X]]
-	[[Category: Zhang, X.]]	+	[[Category: Zhang, X]]
	[[Category: 3-helix bundle]]		[[Category: 3-helix bundle]]
	[[Category: Recombination]]		[[Category: Recombination]]

OCA at 20:00, 29 September 2014

OCA — Mon, 29 Sep 2014 20:00:31 GMT

←Older revision		Revision as of 20:00, 29 September 2014
Line 1:		Line 1:
-	[[~~Image~~:1v92.~~png\|left~~\|200px]]	+	==Solution structure of the UBA domain from p47, a major cofactor of the AAA ATPase p97==
		+	<StructureSection load='1v92' size='340' side='right' caption='[[1v92]], [[NMR_Ensembles_of_Models \| 10 NMR models]]' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[1v92]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1V92 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1V92 FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1v92 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1v92 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1v92 RCSB], [http://www.ebi.ac.uk/pdbsum/1v92 PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/v9/1v92_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	p47 is a major adaptor molecule of the cytosolic AAA ATPase p97. The principal role of the p97-p47 complex is in regulation of membrane fusion events. Mono-ubiquitin recognition by p47 has also been shown to be crucial in the p97-p47-mediated Golgi membrane fusion events. Here, we describe the high-resolution solution structures of the N-terminal UBA domain and the central domain (SEP) from p47. The p47 UBA domain has the characteristic three-helix bundle fold and forms a highly stable complex with ubiquitin. We report the interaction surfaces of the two proteins and present a structure for the p47 UBA-ubiquitin complex. The p47 SEP domain adopts a novel fold with a betabetabetaalphaalphabeta secondary structure arrangement, where beta4 pairs in a parallel fashion to beta1. Based on biophysical studies, we demonstrate a clear propensity for the self-association of p47. Furthermore, p97 N binding abolishes p47 self-association, revealing the potential interaction surfaces for recognition of other domains within p97 or the substrate.

-	~~{{STRUCTURE_1v92\| PDB=1v92 \| SCENE= }}~~	+	Structure, dynamics and interactions of p47, a major adaptor of the AAA ATPase, p97.,Yuan X, Simpson P, McKeown C, Kondo H, Uchiyama K, Wallis R, Dreveny I, Keetch C, Zhang X, Robinson C, Freemont P, Matthews S EMBO J. 2004 Apr 7;23(7):1463-73. Epub 2004 Mar 18. PMID:15029246<ref>PMID:15029246</ref>

-	~~===Solution structure of the UBA domain from p47~~, a ~~major cofactor~~ of the ~~AAA ATPase p97===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_15029246}}~~	+	== References ==
-		+	<references/>
-	~~==About this Structure==~~	+	__TOC__
-	~~[[1v92]] is a 1 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Rattus_norvegicus Rattus norvegicus]~~. ~~Full experimental information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=1V92 OCA].~~	+	</StructureSection>
-		+
-	==~~Reference~~==	+
-	<~~ref group="xtra">PMID:015029246<~~/~~ref~~><~~references group="xtra"~~/>	+
	[[Category: Rattus norvegicus]]		[[Category: Rattus norvegicus]]
	[[Category: Dreveny, I.]]		[[Category: Dreveny, I.]]

OCA: Protected "1v92" [edit=sysop:move=sysop]

OCA — Sat, 05 Jan 2013 13:29:01 GMT

Protected "1v92" [edit=sysop:move=sysop]

←Older revision

Revision as of 13:29, 5 January 2013

OCA at 13:28, 5 January 2013

OCA — Sat, 05 Jan 2013 13:28:58 GMT

←Older revision		Revision as of 13:28, 5 January 2013
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-	{{Seed}}
	[[Image:1v92.png\|left\|200px]]		[[Image:1v92.png\|left\|200px]]

-	<!--
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	{{STRUCTURE_1v92\| PDB=1v92 \| SCENE= }}		{{STRUCTURE_1v92\| PDB=1v92 \| SCENE= }}

	===Solution structure of the UBA domain from p47, a major cofactor of the AAA ATPase p97===		===Solution structure of the UBA domain from p47, a major cofactor of the AAA ATPase p97===

-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_15029246}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where 15029246 is the PubMed ID number.
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	{{ABSTRACT_PUBMED_15029246}}		{{ABSTRACT_PUBMED_15029246}}

	==About this Structure==		==About this Structure==
-	~~1V92~~ is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1V92 OCA].	+	[[1v92]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1V92 OCA].

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~15029246~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:015029246</ref><references group="xtra"/>
	[[Category: Rattus norvegicus]]		[[Category: Rattus norvegicus]]
	[[Category: Dreveny, I.]]		[[Category: Dreveny, I.]]
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	[[Category: Zhang, X.]]		[[Category: Zhang, X.]]
	[[Category: 3-helix bundle]]		[[Category: 3-helix bundle]]
-		+	[[Category: Recombination]]
-	~~''Page seeded by~~ [~~http~~:~~//oca.weizmann.ac.il/oca OCA~~ ] ~~on Mon Feb 16 23:48:48 2009''~~	+