1van - Revision history

OCA at 13:18, 13 October 2021

OCA — Wed, 13 Oct 2021 13:18:55 GMT

←Older revision		Revision as of 13:18, 13 October 2021
Line 4:		Line 4:
	<StructureSection load='1van' size='340' side='right'caption='[[1van]]' scene=''>		<StructureSection load='1van' size='340' side='right'caption='[[1van]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1VAN FirstGlance]. <br>	+	<table><tr><td colspan='2'>For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1VAN FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1van FirstGlance], [~~http~~://www.ebi.ac.uk/pdbsum/1van PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=1van ProSAT]</span></td></tr>	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1van FirstGlance], [https://www.ebi.ac.uk/pdbsum/1van PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1van ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 10:21, 8 January 2020

OCA — Wed, 08 Jan 2020 10:21:52 GMT

←Older revision		Revision as of 10:21, 8 January 2020
Line 2:		Line 2:

	==DIFFERENT MODES OF VANCOMYCIN AND D-ALANYL-D-ALANINE PEPTIDASE BINDING TO CELL WALL PEPTIDE AND A POSSIBLE ROLE FOR THE VANCOMYCIN RESISTANCE PROTEIN==		==DIFFERENT MODES OF VANCOMYCIN AND D-ALANYL-D-ALANINE PEPTIDASE BINDING TO CELL WALL PEPTIDE AND A POSSIBLE ROLE FOR THE VANCOMYCIN RESISTANCE PROTEIN==
-	<StructureSection load='1van' size='340' side='right' caption='[[1van]]' scene=''>	+	<StructureSection load='1van' size='340' side='right'caption='[[1van]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1VAN FirstGlance]. <br>		<table><tr><td colspan='2'>For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1VAN FirstGlance]. <br>
Line 21:		Line 21:
	</StructureSection>		</StructureSection>
	[[Category: Theoretical Model]]		[[Category: Theoretical Model]]
		+	[[Category: Large Structures]]
	[[Category: Knox, J R]]		[[Category: Knox, J R]]

OCA at 07:27, 4 April 2018

OCA — Wed, 04 Apr 2018 07:27:33 GMT

←Older revision		Revision as of 07:27, 4 April 2018
Line 5:		Line 5:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1VAN FirstGlance]. <br>		<table><tr><td colspan='2'>For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1VAN FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1van FirstGlance], [http://www.ebi.ac.uk/pdbsum/1van PDBsum]</span></td></tr>	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1van FirstGlance], [http://www.ebi.ac.uk/pdbsum/1van PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1van ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 10:03, 11 February 2016

OCA — Thu, 11 Feb 2016 10:03:48 GMT

←Older revision		Revision as of 10:03, 11 February 2016
Line 1:		Line 1:
		+	{{Theoretical_model}}
		+
	==DIFFERENT MODES OF VANCOMYCIN AND D-ALANYL-D-ALANINE PEPTIDASE BINDING TO CELL WALL PEPTIDE AND A POSSIBLE ROLE FOR THE VANCOMYCIN RESISTANCE PROTEIN==		==DIFFERENT MODES OF VANCOMYCIN AND D-ALANYL-D-ALANINE PEPTIDASE BINDING TO CELL WALL PEPTIDE AND A POSSIBLE ROLE FOR THE VANCOMYCIN RESISTANCE PROTEIN==
	<StructureSection load='1van' size='340' side='right' caption='[[1van]]' scene=''>		<StructureSection load='1van' size='340' side='right' caption='[[1van]]' scene=''>
Line 18:		Line 20:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Theoretical Model]]
	[[Category: Knox, J R]]		[[Category: Knox, J R]]

OCA at 08:29, 11 September 2015

OCA — Fri, 11 Sep 2015 08:29:00 GMT

←Older revision		Revision as of 08:29, 11 September 2015
Line 13:		Line 13:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 1van" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>

OCA at 13:38, 6 January 2015

OCA — Tue, 06 Jan 2015 13:38:11 GMT

←Older revision		Revision as of 13:38, 6 January 2015
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1VAN FirstGlance]. <br>		<table><tr><td colspan='2'>For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1VAN FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1van FirstGlance], [http://www.ebi.ac.uk/pdbsum/1van PDBsum]</span></td></tr>	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1van FirstGlance], [http://www.ebi.ac.uk/pdbsum/1van PDBsum]</span></td></tr>
-	<table>	+	</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==

OCA at 22:50, 28 September 2014

OCA — Sun, 28 Sep 2014 22:50:49 GMT

←Older revision		Revision as of 22:50, 28 September 2014
Line 1:		Line 1:
-	~~{{Theoretical_model}}~~	+	==DIFFERENT MODES OF VANCOMYCIN AND D-ALANYL-D-ALANINE PEPTIDASE BINDING TO CELL WALL PEPTIDE AND A POSSIBLE ROLE FOR THE VANCOMYCIN RESISTANCE PROTEIN==
		+	<StructureSection load='1van' size='340' side='right' caption='[[1van]]' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1VAN FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1van FirstGlance], [http://www.ebi.ac.uk/pdbsum/1van PDBsum]</span></td></tr>
		+	<table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	A comparison was made of the binding modes of the bacterial cell wall precursor L-lysyl-D-alanyl-D-alanine to the glycopeptide antibiotic vancomycin and to the D-alanyl-D-alanine-cleaving peptidase of Streptomyces sp. strain R61, a model for cell wall-synthesizing enzymes whose X-ray three-dimensional structure is established. In each of the two pairings (vancomycin with peptide and DD-peptidase with peptide), polypeptide backbones were antiparallel, and the antibiotic or enzyme enveloped the peptide substrate from opposite sides. Hydrogen-bonding groups on the substrate which are involved with the DD-peptidase were shown to be different from the ones reported from nuclear magnetic resonance studies to be involved with vancomycin. Because of steric hindrance, the binding of either molecule to the substrate prevents the binding of the other molecule. Binding to the substrate by a D-alanyl-D-alanine-recognizing protein in a manner similar to that used by the DD-peptidase could explain recent observations of vancomycin resistance, in which a new membrane-associated protein has been detected.

-	~~[[Image~~:~~1van~~.~~png\|left\|200px]]~~	+	Different modes of vancomycin and D-alanyl-D-alanine peptidase binding to cell wall peptide and a possible role for the vancomycin resistance protein.,Knox JR, Pratt RF Antimicrob Agents Chemother. 1990 Jul;34(7):1342-7. PMID:2386365<ref>PMID:2386365</ref>

-	~~{{STRUCTURE_1van\| PDB=1van \| SCENE= }}~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	==~~=DIFFERENT MODES OF VANCOMYCIN AND D-ALANYL-D-ALANINE PEPTIDASE BINDING TO CELL WALL PEPTIDE AND A POSSIBLE ROLE FOR THE VANCOMYCIN RESISTANCE PROTEIN===~~	+	== References ==
-		+	<references/>
-	~~{{ABSTRACT_PUBMED_2386365}}~~	+	__TOC__
-		+	</StructureSection>
-	~~==Reference~~==	+
-	<~~ref group="xtra">PMID:002386365<~~/~~ref~~><~~references group="xtra"~~/>	+
	[[Category: Knox, J R]]		[[Category: Knox, J R]]

OCA: Protected "1van" [edit=sysop:move=sysop]

OCA — Sun, 21 Oct 2012 09:41:07 GMT

Protected "1van" [edit=sysop:move=sysop]

←Older revision

Revision as of 09:41, 21 October 2012

OCA at 09:41, 21 October 2012

OCA — Sun, 21 Oct 2012 09:41:02 GMT

←Older revision		Revision as of 09:41, 21 October 2012
Line 1:		Line 1:
	{{Theoretical_model}}		{{Theoretical_model}}
-	~~{{Seed}}~~	+
	[[Image:1van.png\|left\|200px]]		[[Image:1van.png\|left\|200px]]

-	<!--
-	The line below this paragraph, containing "STRUCTURE_1van", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_1van\| PDB=1van \| SCENE= }}		{{STRUCTURE_1van\| PDB=1van \| SCENE= }}

	===DIFFERENT MODES OF VANCOMYCIN AND D-ALANYL-D-ALANINE PEPTIDASE BINDING TO CELL WALL PEPTIDE AND A POSSIBLE ROLE FOR THE VANCOMYCIN RESISTANCE PROTEIN===		===DIFFERENT MODES OF VANCOMYCIN AND D-ALANYL-D-ALANINE PEPTIDASE BINDING TO CELL WALL PEPTIDE AND A POSSIBLE ROLE FOR THE VANCOMYCIN RESISTANCE PROTEIN===

-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_2386365}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where 2386365 is the PubMed ID number.
-	-->
	{{ABSTRACT_PUBMED_2386365}}		{{ABSTRACT_PUBMED_2386365}}
-
-	==About this Structure==
-	Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1VAN OCA].

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~2386365~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:002386365</ref><references group="xtra"/>
	[[Category: Knox, J R]]		[[Category: Knox, J R]]
-
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Apr 8 08:47:31 2010''

OCA at 05:47, 8 April 2010

OCA — Thu, 08 Apr 2010 05:47:32 GMT

←Older revision		Revision as of 05:47, 8 April 2010
Line 1:		Line 1:
-	~~'''Theoretical Model'''~~	+	{{Theoretical_model}}
		+	{{Seed}}
		+	[[Image:1van.png\|left\|200px]]

-	The ~~entry 1VAN~~ is ~~a Theoretical Model titled 'DIFFERENT MODES OF VANCOMYCIN AND D~~-~~ALANYL~~-~~D-ALANINE PEPTIDASE BINDING TO CELL WALL PEPTIDE AND A POSSIBLE ROLE FOR THE VANCOMYCIN RESISTANCE PROTEIN'.~~	+	<!--
		+	The line below this paragraph, containing "STRUCTURE_1van", creates the "Structure Box" on the page.
		+	You may change the PDB parameter (which sets the PDB file loaded into the applet)
		+	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
		+	or leave the SCENE parameter empty for the default display.
		+	-->
		+	{{STRUCTURE_1van\| PDB=1van \| SCENE= }}

-	~~[[Category:Theoretical Model]]~~	+	===DIFFERENT MODES OF VANCOMYCIN AND D-ALANYL-D-ALANINE PEPTIDASE BINDING TO CELL WALL PEPTIDE AND A POSSIBLE ROLE FOR THE VANCOMYCIN RESISTANCE PROTEIN===


-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on ~~Wed Jul 30 09~~:54:~~16 2008~~''	+	<!--
		+	The line below this paragraph, {{ABSTRACT_PUBMED_2386365}}, adds the Publication Abstract to the page
		+	(as it appears on PubMed at http://www.pubmed.gov), where 2386365 is the PubMed ID number.
		+	-->
		+	{{ABSTRACT_PUBMED_2386365}}
		+
		+	==About this Structure==
		+	Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1VAN OCA].
		+
		+	==Reference==
		+	<ref group="xtra">PMID:2386365</ref><references group="xtra"/>
		+	[[Category: Knox, J R]]
		+
		+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Apr 8 08:47:31 2010''