1vcy - Revision history

OCA at 07:52, 25 October 2023

OCA — Wed, 25 Oct 2023 07:52:03 GMT

←Older revision		Revision as of 07:52, 25 October 2023
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	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1vcy]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Volvariella_volvacea Volvariella volvacea]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1VCY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1VCY FirstGlance]. <br>		<table><tr><td colspan='2'>[[1vcy]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Volvariella_volvacea Volvariella volvacea]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1VCY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1VCY FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=MLI:MALONATE+ION'>MLI</scene>~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.6Å</td></tr>
-	<tr id='~~related~~'><td class="sblockLbl"><b>[[~~Related_structure~~\|~~Related~~:]]</b></td><td class="sblockDat"><~~div style~~='~~overflow~~: ~~auto; max-height: 3em;~~'>~~[[1pp0\|1pp0]], [[1pp6\|1pp6]], [[1vgf\|1vgf]]~~</~~div~~></td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MLI:MALONATE+ION'>MLI</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1vcy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1vcy OCA], [https://pdbe.org/1vcy PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1vcy RCSB], [https://www.ebi.ac.uk/pdbsum/1vcy PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1vcy ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1vcy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1vcy OCA], [https://pdbe.org/1vcy PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1vcy RCSB], [https://www.ebi.ac.uk/pdbsum/1vcy PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1vcy ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/Q6USC4_9AGAR Q6USC4_9AGAR]
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
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	[[Category: Large Structures]]		[[Category: Large Structures]]
	[[Category: Volvariella volvacea]]		[[Category: Volvariella volvacea]]
-	[[Category: Liaw, Y C]]	+	[[Category: Liaw Y-C]]
-	[[Category: Lin, J Y]]	+	[[Category: Lin J-Y]]
-	[[Category: Lin, S C]]	+	[[Category: Lin S-C]]
-	[[Category: Lo, Y C]]	+	[[Category: Lo Y-C]]
-	~~[[Category: Toxin~~]]	+

OCA at 13:20, 13 October 2021

OCA — Wed, 13 Oct 2021 13:20:21 GMT

←Older revision		Revision as of 13:20, 13 October 2021
Line 3:		Line 3:
	<StructureSection load='1vcy' size='340' side='right'caption='[[1vcy]], [[Resolution\|resolution]] 2.60Å' scene=''>		<StructureSection load='1vcy' size='340' side='right'caption='[[1vcy]], [[Resolution\|resolution]] 2.60Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1vcy]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Volvariella_volvacea Volvariella volvacea]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1VCY OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1VCY FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1vcy]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Volvariella_volvacea Volvariella volvacea]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1VCY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1VCY FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MLI:MALONATE+ION'>MLI</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MLI:MALONATE+ION'>MLI</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1pp0\|1pp0]], [[1pp6\|1pp6]], [[1vgf\|1vgf]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1pp0\|1pp0]], [[1pp6\|1pp6]], [[1vgf\|1vgf]]</div></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1vcy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1vcy OCA], [~~http~~://pdbe.org/1vcy PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=1vcy RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/1vcy PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=1vcy ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1vcy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1vcy OCA], [https://pdbe.org/1vcy PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1vcy RCSB], [https://www.ebi.ac.uk/pdbsum/1vcy PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1vcy ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
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	==See Also==		==See Also==
	*[[Delta-endotoxin\|Delta-endotoxin]]		*[[Delta-endotoxin\|Delta-endotoxin]]
-	*[[Journal:JMB:1\|Journal:JMB:1]]
	== References ==		== References ==
	<references/>		<references/>

OCA at 10:48, 8 January 2020

OCA — Wed, 08 Jan 2020 10:48:43 GMT

←Older revision		Revision as of 10:48, 8 January 2020
Line 1:		Line 1:

	==VVA2 isoform==		==VVA2 isoform==
-	<StructureSection load='1vcy' size='340' side='right' caption='[[1vcy]], [[Resolution\|resolution]] 2.60Å' scene=''>	+	<StructureSection load='1vcy' size='340' side='right'caption='[[1vcy]], [[Resolution\|resolution]] 2.60Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1vcy]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Volvariella_volvacea Volvariella volvacea]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1VCY OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1VCY FirstGlance]. <br>		<table><tr><td colspan='2'>[[1vcy]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Volvariella_volvacea Volvariella volvacea]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1VCY OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1VCY FirstGlance]. <br>
Line 35:		Line 35:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Large Structures]]
	[[Category: Volvariella volvacea]]		[[Category: Volvariella volvacea]]
	[[Category: Liaw, Y C]]		[[Category: Liaw, Y C]]

OCA at 07:50, 4 April 2018

OCA — Wed, 04 Apr 2018 07:50:48 GMT

←Older revision		Revision as of 07:50, 4 April 2018
Line 1:		Line 1:
		+
	==VVA2 isoform==		==VVA2 isoform==
	<StructureSection load='1vcy' size='340' side='right' caption='[[1vcy]], [[Resolution\|resolution]] 2.60Å' scene=''>		<StructureSection load='1vcy' size='340' side='right' caption='[[1vcy]], [[Resolution\|resolution]] 2.60Å' scene=''>
Line 5:		Line 6:
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MLI:MALONATE+ION'>MLI</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MLI:MALONATE+ION'>MLI</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1pp0\|1pp0]], [[1pp6\|1pp6]], [[1vgf\|1vgf]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1pp0\|1pp0]], [[1pp6\|1pp6]], [[1vgf\|1vgf]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1vcy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1vcy OCA], [http://pdbe.org/1vcy PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1vcy RCSB], [http://www.ebi.ac.uk/pdbsum/1vcy PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1vcy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1vcy OCA], [http://pdbe.org/1vcy PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1vcy RCSB], [http://www.ebi.ac.uk/pdbsum/1vcy PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1vcy ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 11:		Line 12:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/vc/1vcy_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/vc/1vcy_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>

OCA at 14:00, 8 February 2016

OCA — Mon, 08 Feb 2016 14:00:34 GMT

←Older revision		Revision as of 14:00, 8 February 2016
Line 15:		Line 15:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1vcy ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 12:15, 10 September 2015

OCA — Thu, 10 Sep 2015 12:15:53 GMT

←Older revision		Revision as of 12:15, 10 September 2015
Line 5:		Line 5:
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MLI:MALONATE+ION'>MLI</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MLI:MALONATE+ION'>MLI</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1pp0\|1pp0]], [[1pp6\|1pp6]], [[1vgf\|1vgf]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1pp0\|1pp0]], [[1pp6\|1pp6]], [[1vgf\|1vgf]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1vcy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1vcy OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1vcy RCSB], [http://www.ebi.ac.uk/pdbsum/1vcy PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1vcy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1vcy OCA], [http://pdbe.org/1vcy PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1vcy RCSB], [http://www.ebi.ac.uk/pdbsum/1vcy PDBsum]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
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	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 1vcy" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
		+	*[[Delta-endotoxin\|Delta-endotoxin]]
	*[[Journal:JMB:1\|Journal:JMB:1]]		*[[Journal:JMB:1\|Journal:JMB:1]]
	== References ==		== References ==

OCA at 13:12, 6 January 2015

OCA — Tue, 06 Jan 2015 13:12:06 GMT

←Older revision		Revision as of 13:12, 6 January 2015
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1vcy]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Volvariella_volvacea Volvariella volvacea]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1VCY OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1VCY FirstGlance]. <br>		<table><tr><td colspan='2'>[[1vcy]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Volvariella_volvacea Volvariella volvacea]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1VCY OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1VCY FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MLI:MALONATE+ION'>MLI</scene><br>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MLI:MALONATE+ION'>MLI</scene></td></tr>
-	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1pp0\|1pp0]], [[1pp6\|1pp6]], [[1vgf\|1vgf]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1pp0\|1pp0]], [[1pp6\|1pp6]], [[1vgf\|1vgf]]</td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1vcy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1vcy OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1vcy RCSB], [http://www.ebi.ac.uk/pdbsum/1vcy PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1vcy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1vcy OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1vcy RCSB], [http://www.ebi.ac.uk/pdbsum/1vcy PDBsum]</span></td></tr>
-	<table>	+	</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 33:		Line 33:
	</StructureSection>		</StructureSection>
	[[Category: Volvariella volvacea]]		[[Category: Volvariella volvacea]]
-	[[Category: Liaw, Y C.]]	+	[[Category: Liaw, Y C]]
-	[[Category: Lin, J Y.]]	+	[[Category: Lin, J Y]]
-	[[Category: Lin, S C.]]	+	[[Category: Lin, S C]]
-	[[Category: Lo, Y C.]]	+	[[Category: Lo, Y C]]
	[[Category: Toxin]]		[[Category: Toxin]]

OCA at 19:46, 29 September 2014

OCA — Mon, 29 Sep 2014 19:46:33 GMT

←Older revision		Revision as of 19:46, 29 September 2014
Line 1:		Line 1:
-	~~{{STRUCTURE_1vcy~~\| ~~PDB~~=1vcy \| ~~SCENE~~= }}	+	==VVA2 isoform==
-	===~~VVA2 isoform~~===	+	<StructureSection load='1vcy' size='340' side='right' caption='[[1vcy]], [[Resolution\|resolution]] 2.60Å' scene=''>
-	~~{{ABSTRACT_PUBMED_15451675}}~~	+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[1vcy]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Volvariella_volvacea Volvariella volvacea]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1VCY OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1VCY FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MLI:MALONATE+ION'>MLI</scene><br>
		+	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1pp0\|1pp0]], [[1pp6\|1pp6]], [[1vgf\|1vgf]]</td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1vcy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1vcy OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1vcy RCSB], [http://www.ebi.ac.uk/pdbsum/1vcy PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/vc/1vcy_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Membrane adhesion and insertion of protein are essential to all organisms, but the underlying mechanisms remain largely unknown. Membrane pore-forming toxins (PFTs) are potential model systems for studying these mechanisms. We have determined the crystal structures of volvatoxin A2 (VVA2), a fungal PFT from Volvariella volvacea, using Br-multiple-wavelength anomalous diffraction (MAD). The VVA2 structures obtained at pH 4.6, pH 5.5 and pH 6.5 were refined to resolutions of 1.42 A, 2.6 A and 3.2 A, respectively. The structures reveal that the VVA2 monomer contains a single alpha/beta domain. Most of the VVA2 surface is occupied by its oligomerization motif and two putative heparin-binding motifs. Residues Ala91 to Ala101 display several conformations at different pH values, which might be under the control of His87. We also found that the shape of one putative heparin-binding motif in VVA2 appears similar to those found in fibroblast growth factors, and the other one displays a linear polypeptide. Our results suggest several possible intermediates of protein assembly in solution and protein adhering to cell membranes before conformational changes. The electron micrographs of VVA2 molecules in solution, at a protein concentration of 1 microg ml(-1), show that they can assemble into filament-like or braid-like oligomers in a pH-dependent way. In addition, the arc-shaped VVA2 structure obtained at pH 6.5 suggests that VVA2 could form a two-layered helical oligomer with 18 subunits per turn. The structures presented here could be used to elucidate the pore-formation mechanisms of VVA2 and its structural neighbors, Cyt toxins from Bacillus thuringiensis.

-	~~==About this Structure==~~	+	Crystal structures and electron micrographs of fungal volvatoxin A2.,Lin SC, Lo YC, Lin JY, Liaw YC J Mol Biol. 2004 Oct 15;343(2):477-91. PMID:15451675<ref>PMID:15451675</ref>
-	~~[[1vcy]] is a 1 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Volvariella_volvacea Volvariella volvacea]~~. ~~Full crystallographic information is available from [http~~://~~oca~~.~~weizmann~~.ac.il/~~oca-bin/ocashort?id=1VCY OCA].~~	+
		+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>

	==See Also==		==See Also==
	*[[Journal:JMB:1\|Journal:JMB:1]]		*[[Journal:JMB:1\|Journal:JMB:1]]
-		+	== References ==
-	==~~Reference~~==	+	<references/>
-	<~~ref group="xtra">PMID:015451675<~~/~~ref~~><~~ref group="xtra">PMID:000000000</ref><references group="xtra"~~/>	+	__TOC__
		+	</StructureSection>
	[[Category: Volvariella volvacea]]		[[Category: Volvariella volvacea]]
	[[Category: Liaw, Y C.]]		[[Category: Liaw, Y C.]]

OCA at 10:41, 11 March 2013

OCA — Mon, 11 Mar 2013 10:41:48 GMT

←Older revision		Revision as of 10:41, 11 March 2013
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-	[[Image:1vcy.png\|left\|200px]]
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	{{STRUCTURE_1vcy\| PDB=1vcy \| SCENE= }}		{{STRUCTURE_1vcy\| PDB=1vcy \| SCENE= }}
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	===VVA2 isoform===		===VVA2 isoform===
-
	{{ABSTRACT_PUBMED_15451675}}		{{ABSTRACT_PUBMED_15451675}}

OCA: Protected "1vcy" [edit=sysop:move=sysop]

OCA — Wed, 29 Aug 2012 04:01:51 GMT

Protected "1vcy" [edit=sysop:move=sysop]

←Older revision

Revision as of 04:01, 29 August 2012