1w5i - Revision history

OCA at 09:11, 9 May 2024

OCA — Thu, 09 May 2024 09:11:42 GMT

←Older revision		Revision as of 09:11, 9 May 2024
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	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1w5i]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1W5I OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1W5I FirstGlance]. <br>		<table><tr><td colspan='2'>[[1w5i]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1W5I OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1W5I FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1w5i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1w5i OCA], [https://pdbe.org/1w5i PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1w5i RCSB], [https://www.ebi.ac.uk/pdbsum/1w5i PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1w5i ProSAT]</span></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.3Å</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1w5i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1w5i OCA], [https://pdbe.org/1w5i PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1w5i RCSB], [https://www.ebi.ac.uk/pdbsum/1w5i PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1w5i ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
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	==See Also==		==See Also==
		+	*[[Gcn4 3D Structures\|Gcn4 3D Structures]]
	*[[Gnc4 3D Structures\|Gnc4 3D Structures]]		*[[Gnc4 3D Structures\|Gnc4 3D Structures]]
	== References ==		== References ==

OCA at 10:50, 24 November 2022

OCA — Thu, 24 Nov 2022 10:50:22 GMT

←Older revision		Revision as of 10:50, 24 November 2022
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	<StructureSection load='1w5i' size='340' side='right'caption='[[1w5i]], [[Resolution\|resolution]] 2.30Å' scene=''>		<StructureSection load='1w5i' size='340' side='right'caption='[[1w5i]], [[Resolution\|resolution]] 2.30Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1w5i]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1W5I OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1W5I FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1w5i]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1W5I OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1W5I FirstGlance]. <br>
-	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1ce9\|1ce9]], [[1dgc\|1dgc]], [[1env\|1env]], [[1fav\|1fav]], [[1gcl\|1gcl]], [[1gcm\|1gcm]], [[1gk6\|1gk6]], [[1gzl\|1gzl]], [[1ihq\|1ihq]], [[1ij0\|1ij0]], [[1ij1\|1ij1]], [[1ij2\|1ij2]], [[1ij3\|1ij3]], [[1kql\|1kql]], [[1ld4\|1ld4]], [[1llm\|1llm]], [[1nkn\|1nkn]], [[1piq\|1piq]], [[1rb1\|1rb1]], [[1rb4\|1rb4]], [[1rb5\|1rb5]], [[1rb6\|1rb6]], [[1swi\|1swi]], [[1tmz\|1tmz]], [[1m6t\|1m6t]], [[1unt\|1unt]], [[1unu\|1unu]], [[1unv\|1unv]], [[1unw\|1unw]], [[1unx\|1unx]], [[1uny\|1uny]], [[1unz\|1unz]], [[1uo0\|1uo0]], [[1uo1\|1uo1]], [[1uo2\|1uo2]], [[1uo3\|1uo3]], [[1uo4\|1uo4]], [[1uo5\|1uo5]], [[1vzl\|1vzl]], [[1ysa\|1ysa]], [[1zii\|1zii]], [[1zij\|1zij]], [[1zik\|1zik]], [[1zil\|1zil]], [[1zim\|1zim]], [[1zta\|1zta]], [[2dgc\|2dgc]], [[2zta\|2zta]], [[1w5g\|1w5g]], [[1w5h\|1w5h]], [[1w5j\|1w5j]], [[1w5k\|1w5k]], [[1w5l\|1w5l]]</div></td></tr>	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1w5i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1w5i OCA], [https://pdbe.org/1w5i PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1w5i RCSB], [https://www.ebi.ac.uk/pdbsum/1w5i PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1w5i ProSAT]</span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1w5i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1w5i OCA], [https://pdbe.org/1w5i PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1w5i RCSB], [https://www.ebi.ac.uk/pdbsum/1w5i PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1w5i ProSAT]</span></td></tr>	+
	</table>		</table>
	== Function ==		== Function ==
-	[[https://www.uniprot.org/uniprot/GCN4_YEAST GCN4_YEAST]] Is a transcription factor that is responsible for the activation of more than 30 genes required for amino acid or for purine biosynthesis in response to amino acid or purine starvation. Binds and recognize the DNA sequence: 5'-TGA[CG]TCA-3'.	+	[https://www.uniprot.org/uniprot/GCN4_YEAST GCN4_YEAST] Is a transcription factor that is responsible for the activation of more than 30 genes required for amino acid or for purine biosynthesis in response to amino acid or purine starvation. Binds and recognize the DNA sequence: 5'-TGA[CG]TCA-3'.
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
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	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: ~~Ghadiri, M R~~]]	+	[[Category: Saccharomyces cerevisiae]]
-	[[Category: ~~Leman, L J~~]]	+	[[Category: Ghadiri MR]]
-	[[Category: ~~Stout, C D~~]]	+	[[Category: Leman LJ]]
-	[[Category: ~~Yadav, M K~~]]	+	[[Category: Stout CD]]
-	[[Category: ~~Aba]]~~	+	[[Category: Yadav MK]]
-	~~[[Category: Four helix bundle~~]]	+

OCA at 10:30, 17 February 2021

OCA — Wed, 17 Feb 2021 10:30:15 GMT

←Older revision		Revision as of 10:30, 17 February 2021
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	<StructureSection load='1w5i' size='340' side='right'caption='[[1w5i]], [[Resolution\|resolution]] 2.30Å' scene=''>		<StructureSection load='1w5i' size='340' side='right'caption='[[1w5i]], [[Resolution\|resolution]] 2.30Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1w5i]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1W5I OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1W5I FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1w5i]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1W5I OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1W5I FirstGlance]. <br>
-	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1ce9\|1ce9]], [[1dgc\|1dgc]], [[1env\|1env]], [[1fav\|1fav]], [[1gcl\|1gcl]], [[1gcm\|1gcm]], [[1gk6\|1gk6]], [[1gzl\|1gzl]], [[1ihq\|1ihq]], [[1ij0\|1ij0]], [[1ij1\|1ij1]], [[1ij2\|1ij2]], [[1ij3\|1ij3]], [[1kql\|1kql]], [[1ld4\|1ld4]], [[1llm\|1llm]], [[1nkn\|1nkn]], [[1piq\|1piq]], [[1rb1\|1rb1]], [[1rb4\|1rb4]], [[1rb5\|1rb5]], [[1rb6\|1rb6]], [[1swi\|1swi]], [[1tmz\|1tmz]], [[1m6t\|1m6t]], [[1unt\|1unt]], [[1unu\|1unu]], [[1unv\|1unv]], [[1unw\|1unw]], [[1unx\|1unx]], [[1uny\|1uny]], [[1unz\|1unz]], [[1uo0\|1uo0]], [[1uo1\|1uo1]], [[1uo2\|1uo2]], [[1uo3\|1uo3]], [[1uo4\|1uo4]], [[1uo5\|1uo5]], [[1vzl\|1vzl]], [[1ysa\|1ysa]], [[1zii\|1zii]], [[1zij\|1zij]], [[1zik\|1zik]], [[1zil\|1zil]], [[1zim\|1zim]], [[1zta\|1zta]], [[2dgc\|2dgc]], [[2zta\|2zta]], [[1w5g\|1w5g]], [[1w5h\|1w5h]], [[1w5j\|1w5j]], [[1w5k\|1w5k]], [[1w5l\|1w5l]]</td></tr>	+	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1ce9\|1ce9]], [[1dgc\|1dgc]], [[1env\|1env]], [[1fav\|1fav]], [[1gcl\|1gcl]], [[1gcm\|1gcm]], [[1gk6\|1gk6]], [[1gzl\|1gzl]], [[1ihq\|1ihq]], [[1ij0\|1ij0]], [[1ij1\|1ij1]], [[1ij2\|1ij2]], [[1ij3\|1ij3]], [[1kql\|1kql]], [[1ld4\|1ld4]], [[1llm\|1llm]], [[1nkn\|1nkn]], [[1piq\|1piq]], [[1rb1\|1rb1]], [[1rb4\|1rb4]], [[1rb5\|1rb5]], [[1rb6\|1rb6]], [[1swi\|1swi]], [[1tmz\|1tmz]], [[1m6t\|1m6t]], [[1unt\|1unt]], [[1unu\|1unu]], [[1unv\|1unv]], [[1unw\|1unw]], [[1unx\|1unx]], [[1uny\|1uny]], [[1unz\|1unz]], [[1uo0\|1uo0]], [[1uo1\|1uo1]], [[1uo2\|1uo2]], [[1uo3\|1uo3]], [[1uo4\|1uo4]], [[1uo5\|1uo5]], [[1vzl\|1vzl]], [[1ysa\|1ysa]], [[1zii\|1zii]], [[1zij\|1zij]], [[1zik\|1zik]], [[1zil\|1zil]], [[1zim\|1zim]], [[1zta\|1zta]], [[2dgc\|2dgc]], [[2zta\|2zta]], [[1w5g\|1w5g]], [[1w5h\|1w5h]], [[1w5j\|1w5j]], [[1w5k\|1w5k]], [[1w5l\|1w5l]]</div></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1w5i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1w5i OCA], [~~http~~://pdbe.org/1w5i PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=1w5i RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/1w5i PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=1w5i ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1w5i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1w5i OCA], [https://pdbe.org/1w5i PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1w5i RCSB], [https://www.ebi.ac.uk/pdbsum/1w5i PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1w5i ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[~~http~~://www.uniprot.org/uniprot/GCN4_YEAST GCN4_YEAST]] Is a transcription factor that is responsible for the activation of more than 30 genes required for amino acid or for purine biosynthesis in response to amino acid or purine starvation. Binds and recognize the DNA sequence: 5'-TGA[CG]TCA-3'.	+	[[https://www.uniprot.org/uniprot/GCN4_YEAST GCN4_YEAST]] Is a transcription factor that is responsible for the activation of more than 30 genes required for amino acid or for purine biosynthesis in response to amino acid or purine starvation. Binds and recognize the DNA sequence: 5'-TGA[CG]TCA-3'.
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
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	==See Also==		==See Also==
-	*[[~~Gcn4~~\|~~Gcn4~~]]	+	*[[Gnc4 3D Structures\|Gnc4 3D Structures]]
	== References ==		== References ==
	<references/>		<references/>

OCA at 11:47, 10 May 2019

OCA — Fri, 10 May 2019 11:47:47 GMT

←Older revision		Revision as of 11:47, 10 May 2019
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	==ABA does not affect topology of pLI.==		==ABA does not affect topology of pLI.==
-	<StructureSection load='1w5i' size='340' side='right' caption='[[1w5i]], [[Resolution\|resolution]] 2.30Å' scene=''>	+	<StructureSection load='1w5i' size='340' side='right'caption='[[1w5i]], [[Resolution\|resolution]] 2.30Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1w5i]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1W5I OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1W5I FirstGlance]. <br>		<table><tr><td colspan='2'>[[1w5i]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1W5I OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1W5I FirstGlance]. <br>
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Large Structures]]
	[[Category: Ghadiri, M R]]		[[Category: Ghadiri, M R]]
	[[Category: Leman, L J]]		[[Category: Leman, L J]]

OCA at 07:33, 4 April 2018

OCA — Wed, 04 Apr 2018 07:33:11 GMT

←Older revision		Revision as of 07:33, 4 April 2018
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-	==ABA ~~DOES NOT AFFECT TOPOLOGY OF PLI~~.==	+
		+	==ABA does not affect topology of pLI.==
	<StructureSection load='1w5i' size='340' side='right' caption='[[1w5i]], [[Resolution\|resolution]] 2.30Å' scene=''>		<StructureSection load='1w5i' size='340' side='right' caption='[[1w5i]], [[Resolution\|resolution]] 2.30Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1w5i]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1W5I OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1W5I FirstGlance]. <br>		<table><tr><td colspan='2'>[[1w5i]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1W5I OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1W5I FirstGlance]. <br>
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1ce9\|1ce9]], [[1dgc\|1dgc]], [[1env\|1env]], [[1fav\|1fav]], [[1gcl\|1gcl]], [[1gcm\|1gcm]], [[1gk6\|1gk6]], [[1gzl\|1gzl]], [[1ihq\|1ihq]], [[1ij0\|1ij0]], [[1ij1\|1ij1]], [[1ij2\|1ij2]], [[1ij3\|1ij3]], [[1kql\|1kql]], [[1ld4\|1ld4]], [[1llm\|1llm]], [[1nkn\|1nkn]], [[1piq\|1piq]], [[1rb1\|1rb1]], [[1rb4\|1rb4]], [[1rb5\|1rb5]], [[1rb6\|1rb6]], [[1swi\|1swi]], [[1tmz\|1tmz]], [[1m6t\|1m6t]], [[1unt\|1unt]], [[1unu\|1unu]], [[1unv\|1unv]], [[1unw\|1unw]], [[1unx\|1unx]], [[1uny\|1uny]], [[1unz\|1unz]], [[1uo0\|1uo0]], [[1uo1\|1uo1]], [[1uo2\|1uo2]], [[1uo3\|1uo3]], [[1uo4\|1uo4]], [[1uo5\|1uo5]], [[1vzl\|1vzl]], [[1ysa\|1ysa]], [[1zii\|1zii]], [[1zij\|1zij]], [[1zik\|1zik]], [[1zil\|1zil]], [[1zim\|1zim]], [[1zta\|1zta]], [[2dgc\|2dgc]], [[2zta\|2zta]], [[1w5g\|1w5g]], [[1w5h\|1w5h]], [[1w5j\|1w5j]], [[1w5k\|1w5k]], [[1w5l\|1w5l]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1ce9\|1ce9]], [[1dgc\|1dgc]], [[1env\|1env]], [[1fav\|1fav]], [[1gcl\|1gcl]], [[1gcm\|1gcm]], [[1gk6\|1gk6]], [[1gzl\|1gzl]], [[1ihq\|1ihq]], [[1ij0\|1ij0]], [[1ij1\|1ij1]], [[1ij2\|1ij2]], [[1ij3\|1ij3]], [[1kql\|1kql]], [[1ld4\|1ld4]], [[1llm\|1llm]], [[1nkn\|1nkn]], [[1piq\|1piq]], [[1rb1\|1rb1]], [[1rb4\|1rb4]], [[1rb5\|1rb5]], [[1rb6\|1rb6]], [[1swi\|1swi]], [[1tmz\|1tmz]], [[1m6t\|1m6t]], [[1unt\|1unt]], [[1unu\|1unu]], [[1unv\|1unv]], [[1unw\|1unw]], [[1unx\|1unx]], [[1uny\|1uny]], [[1unz\|1unz]], [[1uo0\|1uo0]], [[1uo1\|1uo1]], [[1uo2\|1uo2]], [[1uo3\|1uo3]], [[1uo4\|1uo4]], [[1uo5\|1uo5]], [[1vzl\|1vzl]], [[1ysa\|1ysa]], [[1zii\|1zii]], [[1zij\|1zij]], [[1zik\|1zik]], [[1zil\|1zil]], [[1zim\|1zim]], [[1zta\|1zta]], [[2dgc\|2dgc]], [[2zta\|2zta]], [[1w5g\|1w5g]], [[1w5h\|1w5h]], [[1w5j\|1w5j]], [[1w5k\|1w5k]], [[1w5l\|1w5l]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1w5i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1w5i OCA], [http://pdbe.org/1w5i PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1w5i RCSB], [http://www.ebi.ac.uk/pdbsum/1w5i PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1w5i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1w5i OCA], [http://pdbe.org/1w5i PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1w5i RCSB], [http://www.ebi.ac.uk/pdbsum/1w5i PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1w5i ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==

OCA at 07:52, 10 September 2015

OCA — Thu, 10 Sep 2015 07:52:02 GMT

←Older revision		Revision as of 07:52, 10 September 2015
Line 4:		Line 4:
	<table><tr><td colspan='2'>[[1w5i]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1W5I OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1W5I FirstGlance]. <br>		<table><tr><td colspan='2'>[[1w5i]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1W5I OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1W5I FirstGlance]. <br>
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1ce9\|1ce9]], [[1dgc\|1dgc]], [[1env\|1env]], [[1fav\|1fav]], [[1gcl\|1gcl]], [[1gcm\|1gcm]], [[1gk6\|1gk6]], [[1gzl\|1gzl]], [[1ihq\|1ihq]], [[1ij0\|1ij0]], [[1ij1\|1ij1]], [[1ij2\|1ij2]], [[1ij3\|1ij3]], [[1kql\|1kql]], [[1ld4\|1ld4]], [[1llm\|1llm]], [[1nkn\|1nkn]], [[1piq\|1piq]], [[1rb1\|1rb1]], [[1rb4\|1rb4]], [[1rb5\|1rb5]], [[1rb6\|1rb6]], [[1swi\|1swi]], [[1tmz\|1tmz]], [[1m6t\|1m6t]], [[1unt\|1unt]], [[1unu\|1unu]], [[1unv\|1unv]], [[1unw\|1unw]], [[1unx\|1unx]], [[1uny\|1uny]], [[1unz\|1unz]], [[1uo0\|1uo0]], [[1uo1\|1uo1]], [[1uo2\|1uo2]], [[1uo3\|1uo3]], [[1uo4\|1uo4]], [[1uo5\|1uo5]], [[1vzl\|1vzl]], [[1ysa\|1ysa]], [[1zii\|1zii]], [[1zij\|1zij]], [[1zik\|1zik]], [[1zil\|1zil]], [[1zim\|1zim]], [[1zta\|1zta]], [[2dgc\|2dgc]], [[2zta\|2zta]], [[1w5g\|1w5g]], [[1w5h\|1w5h]], [[1w5j\|1w5j]], [[1w5k\|1w5k]], [[1w5l\|1w5l]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1ce9\|1ce9]], [[1dgc\|1dgc]], [[1env\|1env]], [[1fav\|1fav]], [[1gcl\|1gcl]], [[1gcm\|1gcm]], [[1gk6\|1gk6]], [[1gzl\|1gzl]], [[1ihq\|1ihq]], [[1ij0\|1ij0]], [[1ij1\|1ij1]], [[1ij2\|1ij2]], [[1ij3\|1ij3]], [[1kql\|1kql]], [[1ld4\|1ld4]], [[1llm\|1llm]], [[1nkn\|1nkn]], [[1piq\|1piq]], [[1rb1\|1rb1]], [[1rb4\|1rb4]], [[1rb5\|1rb5]], [[1rb6\|1rb6]], [[1swi\|1swi]], [[1tmz\|1tmz]], [[1m6t\|1m6t]], [[1unt\|1unt]], [[1unu\|1unu]], [[1unv\|1unv]], [[1unw\|1unw]], [[1unx\|1unx]], [[1uny\|1uny]], [[1unz\|1unz]], [[1uo0\|1uo0]], [[1uo1\|1uo1]], [[1uo2\|1uo2]], [[1uo3\|1uo3]], [[1uo4\|1uo4]], [[1uo5\|1uo5]], [[1vzl\|1vzl]], [[1ysa\|1ysa]], [[1zii\|1zii]], [[1zij\|1zij]], [[1zik\|1zik]], [[1zil\|1zil]], [[1zim\|1zim]], [[1zta\|1zta]], [[2dgc\|2dgc]], [[2zta\|2zta]], [[1w5g\|1w5g]], [[1w5h\|1w5h]], [[1w5j\|1w5j]], [[1w5k\|1w5k]], [[1w5l\|1w5l]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1w5i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1w5i OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1w5i RCSB], [http://www.ebi.ac.uk/pdbsum/1w5i PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1w5i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1w5i OCA], [http://pdbe.org/1w5i PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1w5i RCSB], [http://www.ebi.ac.uk/pdbsum/1w5i PDBsum]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 16:		Line 16:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 1w5i" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==

OCA at 20:36, 24 December 2014

OCA — Wed, 24 Dec 2014 20:36:56 GMT

←Older revision		Revision as of 20:36, 24 December 2014
Line 6:		Line 6:
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1w5i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1w5i OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1w5i RCSB], [http://www.ebi.ac.uk/pdbsum/1w5i PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1w5i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1w5i OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1w5i RCSB], [http://www.ebi.ac.uk/pdbsum/1w5i PDBsum]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/GCN4_YEAST GCN4_YEAST]] Is a transcription factor that is responsible for the activation of more than 30 genes required for amino acid or for purine biosynthesis in response to amino acid or purine starvation. Binds and recognize the DNA sequence: 5'-TGA[CG]TCA-3'.
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==

OCA at 06:25, 22 December 2014

OCA — Mon, 22 Dec 2014 06:25:40 GMT

←Older revision		Revision as of 06:25, 22 December 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1w5i]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1W5I OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1W5I FirstGlance]. <br>		<table><tr><td colspan='2'>[[1w5i]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1W5I OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1W5I FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1ce9\|1ce9]], [[1dgc\|1dgc]], [[1env\|1env]], [[1fav\|1fav]], [[1gcl\|1gcl]], [[1gcm\|1gcm]], [[1gk6\|1gk6]], [[1gzl\|1gzl]], [[1ihq\|1ihq]], [[1ij0\|1ij0]], [[1ij1\|1ij1]], [[1ij2\|1ij2]], [[1ij3\|1ij3]], [[1kql\|1kql]], [[1ld4\|1ld4]], [[1llm\|1llm]], [[1nkn\|1nkn]], [[1piq\|1piq]], [[1rb1\|1rb1]], [[1rb4\|1rb4]], [[1rb5\|1rb5]], [[1rb6\|1rb6]], [[1swi\|1swi]], [[1tmz\|1tmz]], [[1m6t\|1m6t]], [[1unt\|1unt]], [[1unu\|1unu]], [[1unv\|1unv]], [[1unw\|1unw]], [[1unx\|1unx]], [[1uny\|1uny]], [[1unz\|1unz]], [[1uo0\|1uo0]], [[1uo1\|1uo1]], [[1uo2\|1uo2]], [[1uo3\|1uo3]], [[1uo4\|1uo4]], [[1uo5\|1uo5]], [[1vzl\|1vzl]], [[1ysa\|1ysa]], [[1zii\|1zii]], [[1zij\|1zij]], [[1zik\|1zik]], [[1zil\|1zil]], [[1zim\|1zim]], [[1zta\|1zta]], [[2dgc\|2dgc]], [[2zta\|2zta]], [[1w5g\|1w5g]], [[1w5h\|1w5h]], [[1w5j\|1w5j]], [[1w5k\|1w5k]], [[1w5l\|1w5l]]</td></tr>	+	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1ce9\|1ce9]], [[1dgc\|1dgc]], [[1env\|1env]], [[1fav\|1fav]], [[1gcl\|1gcl]], [[1gcm\|1gcm]], [[1gk6\|1gk6]], [[1gzl\|1gzl]], [[1ihq\|1ihq]], [[1ij0\|1ij0]], [[1ij1\|1ij1]], [[1ij2\|1ij2]], [[1ij3\|1ij3]], [[1kql\|1kql]], [[1ld4\|1ld4]], [[1llm\|1llm]], [[1nkn\|1nkn]], [[1piq\|1piq]], [[1rb1\|1rb1]], [[1rb4\|1rb4]], [[1rb5\|1rb5]], [[1rb6\|1rb6]], [[1swi\|1swi]], [[1tmz\|1tmz]], [[1m6t\|1m6t]], [[1unt\|1unt]], [[1unu\|1unu]], [[1unv\|1unv]], [[1unw\|1unw]], [[1unx\|1unx]], [[1uny\|1uny]], [[1unz\|1unz]], [[1uo0\|1uo0]], [[1uo1\|1uo1]], [[1uo2\|1uo2]], [[1uo3\|1uo3]], [[1uo4\|1uo4]], [[1uo5\|1uo5]], [[1vzl\|1vzl]], [[1ysa\|1ysa]], [[1zii\|1zii]], [[1zij\|1zij]], [[1zik\|1zik]], [[1zil\|1zil]], [[1zim\|1zim]], [[1zta\|1zta]], [[2dgc\|2dgc]], [[2zta\|2zta]], [[1w5g\|1w5g]], [[1w5h\|1w5h]], [[1w5j\|1w5j]], [[1w5k\|1w5k]], [[1w5l\|1w5l]]</td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1w5i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1w5i OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1w5i RCSB], [http://www.ebi.ac.uk/pdbsum/1w5i PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1w5i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1w5i OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1w5i RCSB], [http://www.ebi.ac.uk/pdbsum/1w5i PDBsum]</span></td></tr>
-	<table>	+	</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 21:		Line 21:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Ghadiri, M R.]]	+	[[Category: Ghadiri, M R]]
-	[[Category: Leman, L J.]]	+	[[Category: Leman, L J]]
-	[[Category: Stout, C D.]]	+	[[Category: Stout, C D]]
-	[[Category: Yadav, M K.]]	+	[[Category: Yadav, M K]]
	[[Category: Aba]]		[[Category: Aba]]
	[[Category: Four helix bundle]]		[[Category: Four helix bundle]]

OCA at 07:01, 9 June 2014

OCA — Mon, 09 Jun 2014 07:01:25 GMT

←Older revision		Revision as of 07:01, 9 June 2014
Line 1:		Line 1:
-	[[~~Image:~~1w5i.~~png~~\|~~left~~\|~~200px~~]]	+	==ABA DOES NOT AFFECT TOPOLOGY OF PLI.==
		+	<StructureSection load='1w5i' size='340' side='right' caption='[[1w5i]], [[Resolution\|resolution]] 2.30Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[1w5i]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1W5I OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1W5I FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1ce9\|1ce9]], [[1dgc\|1dgc]], [[1env\|1env]], [[1fav\|1fav]], [[1gcl\|1gcl]], [[1gcm\|1gcm]], [[1gk6\|1gk6]], [[1gzl\|1gzl]], [[1ihq\|1ihq]], [[1ij0\|1ij0]], [[1ij1\|1ij1]], [[1ij2\|1ij2]], [[1ij3\|1ij3]], [[1kql\|1kql]], [[1ld4\|1ld4]], [[1llm\|1llm]], [[1nkn\|1nkn]], [[1piq\|1piq]], [[1rb1\|1rb1]], [[1rb4\|1rb4]], [[1rb5\|1rb5]], [[1rb6\|1rb6]], [[1swi\|1swi]], [[1tmz\|1tmz]], [[1m6t\|1m6t]], [[1unt\|1unt]], [[1unu\|1unu]], [[1unv\|1unv]], [[1unw\|1unw]], [[1unx\|1unx]], [[1uny\|1uny]], [[1unz\|1unz]], [[1uo0\|1uo0]], [[1uo1\|1uo1]], [[1uo2\|1uo2]], [[1uo3\|1uo3]], [[1uo4\|1uo4]], [[1uo5\|1uo5]], [[1vzl\|1vzl]], [[1ysa\|1ysa]], [[1zii\|1zii]], [[1zij\|1zij]], [[1zik\|1zik]], [[1zil\|1zil]], [[1zim\|1zim]], [[1zta\|1zta]], [[2dgc\|2dgc]], [[2zta\|2zta]], [[1w5g\|1w5g]], [[1w5h\|1w5h]], [[1w5j\|1w5j]], [[1w5k\|1w5k]], [[1w5l\|1w5l]]</td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1w5i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1w5i OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1w5i RCSB], [http://www.ebi.ac.uk/pdbsum/1w5i PDBsum]</span></td></tr>
		+	<table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Cavities and clefts are frequently important sites of interaction between natural enzymes or receptors and their corresponding substrate or ligand molecules and exemplify the types of molecular surfaces that would facilitate engineering of artificial catalysts and receptors. Even so, structural characterizations of designed cavities are rare. To address this issue, we performed a systematic study of the structural effects of single-amino acid substitutions within the hydrophobic cores of tetrameric coiled-coil peptides. Peptides containing single glycine, serine, alanine, or threonine amino acid substitutions at the buried L9, L16, L23, and I26 hydrophobic core positions of a GCN4-based sequence were synthesized and studied by solution-phase and crystallographic techniques. All peptides adopt the expected tetrameric state and contain tunnels or internal cavities ranging in size from 80 to 370 A(3). Two closely related sequences containing an L16G substitution, one of which adopts an antiparallel configuration and one of which adopts a parallel configuration, illustrate that cavities of different volumes and shapes can be engineered from identical core substitutions. Finally, we demonstrate that two of the peptides (L9G and L9A) bind the small molecule iodobenzene when present during crystallization, leaving the general peptide quaternary structure intact but altering the local peptide conformation and certain superhelical parameters. These high-resolution descriptions of varied molecular surfaces within solvent-occluded internal cavities illustrate the breadth of design space available in even closely related peptides and offer valuable models for the engineering of de novo helical proteins.

-	~~{{STRUCTURE_1w5i\| PDB=1w5i \| SCENE= }}~~	+	Structure-based engineering of internal cavities in coiled-coil peptides.,Yadav MK, Redman JE, Leman LJ, Alvarez-Gutierrez JM, Zhang Y, Stout CD, Ghadiri MR Biochemistry. 2005 Jul 19;44(28):9723-32. PMID:16008357<ref>PMID:16008357</ref>

-	~~===ABA DOES NOT AFFECT TOPOLOGY OF PLI~~.~~===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>

-	~~{{ABSTRACT_PUBMED_16008357}}~~	+	==See Also==
-		+	*[[Gcn4\|Gcn4]]
-	==~~About this Structure~~==	+	== References ==
-	[[~~1w5i~~]] ~~is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1W5I OCA].~~	+	<references/>
-		+	__TOC__
-	==~~Reference~~==	+	</StructureSection>
-	<~~ref group="xtra">PMID:016008357<~~/~~ref~~><~~ref group="xtra">PMID:016584182</ref><references group="xtra"~~/>	+
	[[Category: Ghadiri, M R.]]		[[Category: Ghadiri, M R.]]
	[[Category: Leman, L J.]]		[[Category: Leman, L J.]]

OCA: Protected "1w5i" [edit=sysop:move=sysop]

OCA — Tue, 14 Aug 2012 18:29:54 GMT

Protected "1w5i" [edit=sysop:move=sysop]

←Older revision

Revision as of 18:29, 14 August 2012