1wa0 - Revision history

OCA at 13:25, 13 December 2023

OCA — Wed, 13 Dec 2023 13:25:16 GMT

←Older revision		Revision as of 13:25, 13 December 2023
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	<StructureSection load='1wa0' size='340' side='right'caption='[[1wa0]], [[Resolution\|resolution]] 1.60Å' scene=''>		<StructureSection load='1wa0' size='340' side='right'caption='[[1wa0]], [[Resolution\|resolution]] 1.60Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1wa0]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/~~"achromobacter_xylosoxidans"_yabuuchi_and_ohyama_1971 "achromobacter~~ xylosoxidans~~" yabuuchi and ohyama 1971~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WA0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1WA0 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1wa0]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Achromobacter_xylosoxidans Achromobacter xylosoxidans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WA0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1WA0 FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CU:COPPER+(II)+ION'>CU</scene>, <scene name='pdbligand=MES:2-(N-MORPHOLINO)-ETHANESULFONIC+ACID'>MES</scene>, <scene name='pdbligand=PG4:TETRAETHYLENE+GLYCOL'>PG4</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene~~></td></tr>~~	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.6Å</td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1bq5\|1bq5]], [[1gs6\|1gs6]], [[1gs7\|1gs7]], [[1gs8\|1gs8]], [[1hau\|1hau]], [[1haw\|1haw]], [[1ndt\|1ndt]], [[1oe1\|1oe1]], [[1oe2\|1oe2]], [[1oe3\|1oe3]], [[1wa1\|1wa1]], [[1wa2\|1wa2]], [[1wae\|1wae]]</div></td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CU:COPPER+(II)+ION'>CU</scene>, <scene name='pdbligand=MES:2-(N-MORPHOLINO)-ETHANESULFONIC+ACID'>MES</scene>, <scene name='pdbligand=PG4:TETRAETHYLENE+GLYCOL'>PG4</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1wa0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1wa0 OCA], [https://pdbe.org/1wa0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1wa0 RCSB], [https://www.ebi.ac.uk/pdbsum/1wa0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1wa0 ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1wa0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1wa0 OCA], [https://pdbe.org/1wa0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1wa0 RCSB], [https://www.ebi.ac.uk/pdbsum/1wa0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1wa0 ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/O68601_ALCXX O68601_ALCXX]
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Achromobacter xylosoxidans ~~yabuuchi and ohyama 1971~~]]	+	[[Category: Achromobacter xylosoxidans]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Antonyuk~~, S V~~]]	+	[[Category: Antonyuk SV]]
-	[[Category: Barrett~~, M L~~]]	+	[[Category: Barrett ML]]
-	[[Category: Eady~~, R R~~]]	+	[[Category: Eady RR]]
-	[[Category: Harris~~, R L~~]]	+	[[Category: Harris RL]]
-	[[Category: Hasnain~~, S S~~]]	+	[[Category: Hasnain SS]]
-	[[Category: Hough~~, M A~~]]	+	[[Category: Hough MA]]
-	[[Category: Sawers, G]]	+	[[Category: Sawers G]]
-	[[Category: Strange~~, R W]]~~	+	[[Category: Strange RW]]
-	~~[[Category: Denitrification]]~~	+
-	~~[[Category: Nitrite reductase]]~~	+
-	~~[[Category: Oxidoreductase]]~~	+
-	~~[[Category: Reductase]]~~	+
-	~~[[Category: W138h mutant~~]]	+

OCA at 07:09, 24 February 2021

OCA — Wed, 24 Feb 2021 07:09:16 GMT

←Older revision		Revision as of 07:09, 24 February 2021
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	<StructureSection load='1wa0' size='340' side='right'caption='[[1wa0]], [[Resolution\|resolution]] 1.60Å' scene=''>		<StructureSection load='1wa0' size='340' side='right'caption='[[1wa0]], [[Resolution\|resolution]] 1.60Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1wa0]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/"achromobacter_xylosoxidans"_yabuuchi_and_ohyama_1971 "achromobacter xylosoxidans" yabuuchi and ohyama 1971]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WA0 OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1WA0 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1wa0]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/"achromobacter_xylosoxidans"_yabuuchi_and_ohyama_1971 "achromobacter xylosoxidans" yabuuchi and ohyama 1971]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WA0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1WA0 FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CU:COPPER+(II)+ION'>CU</scene>, <scene name='pdbligand=MES:2-(N-MORPHOLINO)-ETHANESULFONIC+ACID'>MES</scene>, <scene name='pdbligand=PG4:TETRAETHYLENE+GLYCOL'>PG4</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CU:COPPER+(II)+ION'>CU</scene>, <scene name='pdbligand=MES:2-(N-MORPHOLINO)-ETHANESULFONIC+ACID'>MES</scene>, <scene name='pdbligand=PG4:TETRAETHYLENE+GLYCOL'>PG4</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1bq5\|1bq5]], [[1gs6\|1gs6]], [[1gs7\|1gs7]], [[1gs8\|1gs8]], [[1hau\|1hau]], [[1haw\|1haw]], [[1ndt\|1ndt]], [[1oe1\|1oe1]], [[1oe2\|1oe2]], [[1oe3\|1oe3]], [[1wa1\|1wa1]], [[1wa2\|1wa2]], [[1wae\|1wae]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1bq5\|1bq5]], [[1gs6\|1gs6]], [[1gs7\|1gs7]], [[1gs8\|1gs8]], [[1hau\|1hau]], [[1haw\|1haw]], [[1ndt\|1ndt]], [[1oe1\|1oe1]], [[1oe2\|1oe2]], [[1oe3\|1oe3]], [[1wa1\|1wa1]], [[1wa2\|1wa2]], [[1wae\|1wae]]</div></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1wa0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1wa0 OCA], [~~http~~://pdbe.org/1wa0 PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=1wa0 RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/1wa0 PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=1wa0 ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1wa0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1wa0 OCA], [https://pdbe.org/1wa0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1wa0 RCSB], [https://www.ebi.ac.uk/pdbsum/1wa0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1wa0 ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
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	==See Also==		==See Also==
-	*[[Nitrite reductase\|Nitrite reductase]]	+	*[[Nitrite reductase 3D structures\|Nitrite reductase 3D structures]]
	== References ==		== References ==
	<references/>		<references/>

OCA at 07:08, 23 May 2019

OCA — Thu, 23 May 2019 07:08:51 GMT

←Older revision		Revision as of 07:08, 23 May 2019
Line 1:		Line 1:

	==Crystal Structure Of W138H Mutant Of Alcaligenes Xylosoxidans Nitrite Reductase==		==Crystal Structure Of W138H Mutant Of Alcaligenes Xylosoxidans Nitrite Reductase==
-	<StructureSection load='1wa0' size='340' side='right' caption='[[1wa0]], [[Resolution\|resolution]] 1.60Å' scene=''>	+	<StructureSection load='1wa0' size='340' side='right'caption='[[1wa0]], [[Resolution\|resolution]] 1.60Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1wa0]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"achromobacter_xylosoxidans"_yabuuchi_and_ohyama_1971 "achromobacter xylosoxidans" yabuuchi and ohyama 1971]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WA0 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1WA0 FirstGlance]. <br>		<table><tr><td colspan='2'>[[1wa0]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"achromobacter_xylosoxidans"_yabuuchi_and_ohyama_1971 "achromobacter xylosoxidans" yabuuchi and ohyama 1971]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WA0 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1WA0 FirstGlance]. <br>
Line 35:		Line 35:
	</StructureSection>		</StructureSection>
	[[Category: Achromobacter xylosoxidans yabuuchi and ohyama 1971]]		[[Category: Achromobacter xylosoxidans yabuuchi and ohyama 1971]]
		+	[[Category: Large Structures]]
	[[Category: Antonyuk, S V]]		[[Category: Antonyuk, S V]]
	[[Category: Barrett, M L]]		[[Category: Barrett, M L]]

OCA at 16:43, 11 April 2018

OCA — Wed, 11 Apr 2018 16:43:45 GMT

←Older revision		Revision as of 16:43, 11 April 2018
Line 1:		Line 1:
-	==~~CRYSTAL STRUCTURE OF~~ W138H ~~MUTANT OF ALCALIGENES XYLOSOXIDANS NITRITE REDUCTASE~~==	+
		+	==Crystal Structure Of W138H Mutant Of Alcaligenes Xylosoxidans Nitrite Reductase==
	<StructureSection load='1wa0' size='340' side='right' caption='[[1wa0]], [[Resolution\|resolution]] 1.60Å' scene=''>		<StructureSection load='1wa0' size='340' side='right' caption='[[1wa0]], [[Resolution\|resolution]] 1.60Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
Line 5:		Line 6:
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CU:COPPER+(II)+ION'>CU</scene>, <scene name='pdbligand=MES:2-(N-MORPHOLINO)-ETHANESULFONIC+ACID'>MES</scene>, <scene name='pdbligand=PG4:TETRAETHYLENE+GLYCOL'>PG4</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CU:COPPER+(II)+ION'>CU</scene>, <scene name='pdbligand=MES:2-(N-MORPHOLINO)-ETHANESULFONIC+ACID'>MES</scene>, <scene name='pdbligand=PG4:TETRAETHYLENE+GLYCOL'>PG4</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1bq5\|1bq5]], [[1gs6\|1gs6]], [[1gs7\|1gs7]], [[1gs8\|1gs8]], [[1hau\|1hau]], [[1haw\|1haw]], [[1ndt\|1ndt]], [[1oe1\|1oe1]], [[1oe2\|1oe2]], [[1oe3\|1oe3]], [[1wa1\|1wa1]], [[1wa2\|1wa2]], [[1wae\|1wae]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1bq5\|1bq5]], [[1gs6\|1gs6]], [[1gs7\|1gs7]], [[1gs8\|1gs8]], [[1hau\|1hau]], [[1haw\|1haw]], [[1ndt\|1ndt]], [[1oe1\|1oe1]], [[1oe2\|1oe2]], [[1oe3\|1oe3]], [[1wa1\|1wa1]], [[1wa2\|1wa2]], [[1wae\|1wae]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1wa0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1wa0 OCA], [http://pdbe.org/1wa0 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1wa0 RCSB], [http://www.ebi.ac.uk/pdbsum/1wa0 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1wa0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1wa0 OCA], [http://pdbe.org/1wa0 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1wa0 RCSB], [http://www.ebi.ac.uk/pdbsum/1wa0 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1wa0 ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 11:		Line 12:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/wa/1wa0_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/wa/1wa0_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
Line 28:		Line 29:

	==See Also==		==See Also==
-	*[[~~Nitric~~ reductase\|~~Nitric~~ reductase]]	+	*[[Nitrite reductase\|Nitrite reductase]]
	== References ==		== References ==
	<references/>		<references/>

OCA at 16:00, 9 February 2016

OCA — Tue, 09 Feb 2016 16:00:42 GMT

←Older revision		Revision as of 16:00, 9 February 2016
Line 15:		Line 15:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1wa0 ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 23:48, 10 September 2015

OCA — Thu, 10 Sep 2015 23:48:56 GMT

←Older revision		Revision as of 23:48, 10 September 2015
Line 2:		Line 2:
	<StructureSection load='1wa0' size='340' side='right' caption='[[1wa0]], [[Resolution\|resolution]] 1.60Å' scene=''>		<StructureSection load='1wa0' size='340' side='right' caption='[[1wa0]], [[Resolution\|resolution]] 1.60Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1wa0]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Achromobacter_xylosoxidans Achromobacter~~ xylosoxidans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WA0 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1WA0 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1wa0]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"achromobacter_xylosoxidans"_yabuuchi_and_ohyama_1971 "achromobacter xylosoxidans" yabuuchi and ohyama 1971]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WA0 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1WA0 FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CU:COPPER+(II)+ION'>CU</scene>, <scene name='pdbligand=MES:2-(N-MORPHOLINO)-ETHANESULFONIC+ACID'>MES</scene>, <scene name='pdbligand=PG4:TETRAETHYLENE+GLYCOL'>PG4</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CU:COPPER+(II)+ION'>CU</scene>, <scene name='pdbligand=MES:2-(N-MORPHOLINO)-ETHANESULFONIC+ACID'>MES</scene>, <scene name='pdbligand=PG4:TETRAETHYLENE+GLYCOL'>PG4</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1bq5\|1bq5]], [[1gs6\|1gs6]], [[1gs7\|1gs7]], [[1gs8\|1gs8]], [[1hau\|1hau]], [[1haw\|1haw]], [[1ndt\|1ndt]], [[1oe1\|1oe1]], [[1oe2\|1oe2]], [[1oe3\|1oe3]], [[1wa1\|1wa1]], [[1wa2\|1wa2]], [[1wae\|1wae]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1bq5\|1bq5]], [[1gs6\|1gs6]], [[1gs7\|1gs7]], [[1gs8\|1gs8]], [[1hau\|1hau]], [[1haw\|1haw]], [[1ndt\|1ndt]], [[1oe1\|1oe1]], [[1oe2\|1oe2]], [[1oe3\|1oe3]], [[1wa1\|1wa1]], [[1wa2\|1wa2]], [[1wae\|1wae]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1wa0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1wa0 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1wa0 RCSB], [http://www.ebi.ac.uk/pdbsum/1wa0 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1wa0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1wa0 OCA], [http://pdbe.org/1wa0 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1wa0 RCSB], [http://www.ebi.ac.uk/pdbsum/1wa0 PDBsum]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 25:		Line 25:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 1wa0" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
Line 32:		Line 33:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Achromobacter xylosoxidans]]	+	[[Category: Achromobacter xylosoxidans yabuuchi and ohyama 1971]]
	[[Category: Antonyuk, S V]]		[[Category: Antonyuk, S V]]
	[[Category: Barrett, M L]]		[[Category: Barrett, M L]]

OCA at 14:05, 6 January 2015

OCA — Tue, 06 Jan 2015 14:05:59 GMT

←Older revision		Revision as of 14:05, 6 January 2015
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1wa0]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Achromobacter_xylosoxidans Achromobacter xylosoxidans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WA0 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1WA0 FirstGlance]. <br>		<table><tr><td colspan='2'>[[1wa0]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Achromobacter_xylosoxidans Achromobacter xylosoxidans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WA0 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1WA0 FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CU:COPPER+(II)+ION'>CU</scene>, <scene name='pdbligand=MES:2-(N-MORPHOLINO)-ETHANESULFONIC+ACID'>MES</scene>, <scene name='pdbligand=PG4:TETRAETHYLENE+GLYCOL'>PG4</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene><br>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CU:COPPER+(II)+ION'>CU</scene>, <scene name='pdbligand=MES:2-(N-MORPHOLINO)-ETHANESULFONIC+ACID'>MES</scene>, <scene name='pdbligand=PG4:TETRAETHYLENE+GLYCOL'>PG4</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
-	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1bq5\|1bq5]], [[1gs6\|1gs6]], [[1gs7\|1gs7]], [[1gs8\|1gs8]], [[1hau\|1hau]], [[1haw\|1haw]], [[1ndt\|1ndt]], [[1oe1\|1oe1]], [[1oe2\|1oe2]], [[1oe3\|1oe3]], [[1wa1\|1wa1]], [[1wa2\|1wa2]], [[1wae\|1wae]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1bq5\|1bq5]], [[1gs6\|1gs6]], [[1gs7\|1gs7]], [[1gs8\|1gs8]], [[1hau\|1hau]], [[1haw\|1haw]], [[1ndt\|1ndt]], [[1oe1\|1oe1]], [[1oe2\|1oe2]], [[1oe3\|1oe3]], [[1wa1\|1wa1]], [[1wa2\|1wa2]], [[1wae\|1wae]]</td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1wa0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1wa0 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1wa0 RCSB], [http://www.ebi.ac.uk/pdbsum/1wa0 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1wa0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1wa0 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1wa0 RCSB], [http://www.ebi.ac.uk/pdbsum/1wa0 PDBsum]</span></td></tr>
-	<table>	+	</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 33:		Line 33:
	</StructureSection>		</StructureSection>
	[[Category: Achromobacter xylosoxidans]]		[[Category: Achromobacter xylosoxidans]]
-	[[Category: Antonyuk, S V.]]	+	[[Category: Antonyuk, S V]]
-	[[Category: Barrett, M L.]]	+	[[Category: Barrett, M L]]
-	[[Category: Eady, R R.]]	+	[[Category: Eady, R R]]
-	[[Category: Harris, R L.]]	+	[[Category: Harris, R L]]
-	[[Category: Hasnain, S S.]]	+	[[Category: Hasnain, S S]]
-	[[Category: Hough, M A.]]	+	[[Category: Hough, M A]]
-	[[Category: Sawers, G.]]	+	[[Category: Sawers, G]]
-	[[Category: Strange, R W.]]	+	[[Category: Strange, R W]]
	[[Category: Denitrification]]		[[Category: Denitrification]]
	[[Category: Nitrite reductase]]		[[Category: Nitrite reductase]]

OCA at 20:40, 28 September 2014

OCA — Sun, 28 Sep 2014 20:40:48 GMT

←Older revision		Revision as of 20:40, 28 September 2014
Line 1:		Line 1:
-	[[~~Image:~~1wa0.~~png~~\|~~left~~\|200px]]	+	==CRYSTAL STRUCTURE OF W138H MUTANT OF ALCALIGENES XYLOSOXIDANS NITRITE REDUCTASE==
		+	<StructureSection load='1wa0' size='340' side='right' caption='[[1wa0]], [[Resolution\|resolution]] 1.60Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[1wa0]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Achromobacter_xylosoxidans Achromobacter xylosoxidans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WA0 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1WA0 FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CU:COPPER+(II)+ION'>CU</scene>, <scene name='pdbligand=MES:2-(N-MORPHOLINO)-ETHANESULFONIC+ACID'>MES</scene>, <scene name='pdbligand=PG4:TETRAETHYLENE+GLYCOL'>PG4</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene><br>
		+	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1bq5\|1bq5]], [[1gs6\|1gs6]], [[1gs7\|1gs7]], [[1gs8\|1gs8]], [[1hau\|1hau]], [[1haw\|1haw]], [[1ndt\|1ndt]], [[1oe1\|1oe1]], [[1oe2\|1oe2]], [[1oe3\|1oe3]], [[1wa1\|1wa1]], [[1wa2\|1wa2]], [[1wae\|1wae]]</td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1wa0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1wa0 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1wa0 RCSB], [http://www.ebi.ac.uk/pdbsum/1wa0 PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/wa/1wa0_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Dissimilatory nitrite reductase catalyses the reduction of nitrite to nitric oxide within the key biological process of denitrification. We present biochemical and structural results on two key mutants, one postulated to be important for the interaction with the partner protein and the other for substrate entry. Trp138, adjacent to one of the type-1 Cu ligands, is one of the residues surrounding a small depression speculated to be important in complex formation with the physiological redox partners, azurin I and II. Our data reveal that the Trp138His mutant is fully active using methyl viologen as an artificial electron donor, but there is a large decrease in activity using azurin I. These observations together with its crystal structure at a high resolution of 1.6 A confirm the importance of Trp138 in electron transfer and thus in productive interaction with azurin. A "hydrophobic pocket" on the protein surface has been identified as the channel through which nitrite may be guided to the catalytic type-2 Cu site. Glu133 and His313 at the opening of the pocket are conserved among most blue and green copper nitrite reductases (CuNiRs). The failure to soak the substrate into our high-resolution crystal form of native and mutant CuNiRs has been linked to the observation of an extraneous poly(ethylene glycol) (PEG) molecule interacting with His313. We present the crystal structure of His313Gln and the substrate-bound mutant at high resolutions of 1.65 and 1.72 A, respectively. The observation of the substrate-bound structure for the His313Gln mutant and inhibitory studies with PEG establishes the role of the hydrophobic pocket as the port of substrate entry.

-	~~{{STRUCTURE_1wa0\| PDB=1wa0 \| SCENE= }}~~	+	Insights into redox partner interactions and substrate binding in nitrite reductase from Alcaligenes xylosoxidans: crystal structures of the Trp138His and His313Gln mutants.,Barrett ML, Harris RL, Antonyuk S, Hough MA, Ellis MJ, Sawers G, Eady RR, Hasnain SS Biochemistry. 2004 Dec 28;43(51):16311-9. PMID:15610025<ref>PMID:15610025</ref>

-	~~===CRYSTAL STRUCTURE OF W138H MUTANT OF ALCALIGENES XYLOSOXIDANS NITRITE REDUCTASE===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_15610025}}~~	+
-		+
-	~~==About this Structure==~~	+
-	~~[[1wa0]] is~~ a ~~1 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Achromobacter_xylosoxidans Achromobacter xylosoxidans]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=1WA0 OCA].~~	+

	==See Also==		==See Also==
	*[[Nitric reductase\|Nitric reductase]]		*[[Nitric reductase\|Nitric reductase]]
-		+	== References ==
-	==~~Reference~~==	+	<references/>
-	<~~ref group="xtra">PMID:015610025<~~/~~ref~~><~~references group="xtra"~~/>	+	__TOC__
		+	</StructureSection>
	[[Category: Achromobacter xylosoxidans]]		[[Category: Achromobacter xylosoxidans]]
	[[Category: Antonyuk, S V.]]		[[Category: Antonyuk, S V.]]

OCA at 14:22, 20 October 2012

OCA — Sat, 20 Oct 2012 14:22:48 GMT

←Older revision		Revision as of 14:22, 20 October 2012
Line 8:		Line 8:

	==About this Structure==		==About this Structure==
-	[[1wa0]] is a 1 chain structure ~~of [[Nitric reductase]]~~ with sequence from [http://en.wikipedia.org/wiki/Achromobacter_xylosoxidans Achromobacter xylosoxidans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WA0 OCA].	+	[[1wa0]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Achromobacter_xylosoxidans Achromobacter xylosoxidans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WA0 OCA].

	==See Also==		==See Also==

OCA: Protected "1wa0" [edit=sysop:move=sysop]

OCA — Thu, 26 Jul 2012 14:57:54 GMT

Protected "1wa0" [edit=sysop:move=sysop]

←Older revision

Revision as of 14:57, 26 July 2012