1wkz - Revision history

OCA at 07:56, 25 October 2023

OCA — Wed, 25 Oct 2023 07:56:43 GMT

←Older revision		Revision as of 07:56, 25 October 2023
Line 3:		Line 3:
	<StructureSection load='1wkz' size='340' side='right'caption='[[1wkz]], [[Resolution\|resolution]] 3.40Å' scene=''>		<StructureSection load='1wkz' size='340' side='right'caption='[[1wkz]], [[Resolution\|resolution]] 3.40Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1wkz]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Thema Thema~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WKZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1WKZ FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1wkz]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermotoga_maritima_MSB8 Thermotoga maritima MSB8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WKZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1WKZ FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 3.4Å</td></tr>
-	<tr id='~~related~~'><td class="sblockLbl"><b>[[~~Related_structure~~\|~~Related~~:]]</b></td><td class="sblockDat"~~><div style='overflow: auto; max-height: 3em;'>[[1v4e\|1v4e]], [[1v4h\|1v4h]], [[1v4j\|1v4j]], [[1v4k\|1v4k]], [[1v4i\|1v4i]], [[1wl0\|1wl0]], [[1wl1\|1wl1]], [[1wl2\|1wl2]], [[1wl3\|1wl3]]</div></td></tr>~~	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-	~~<tr~~ id~~='activity'><td class~~="~~sblockLbl~~"><~~b>Activity:</b></td><td class~~=~~"sblockDat"><span class~~=~~'plainlinks~~'>~~[https://en.wikipedia.org/wiki/Transferase Transferase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.5.1.84 and 2.5.1.85 2.5.1.84 and 2.5.1.85]~~ </~~span~~></td></tr>	+
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1wkz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1wkz OCA], [https://pdbe.org/1wkz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1wkz RCSB], [https://www.ebi.ac.uk/pdbsum/1wkz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1wkz ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1wkz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1wkz OCA], [https://pdbe.org/1wkz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1wkz RCSB], [https://www.ebi.ac.uk/pdbsum/1wkz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1wkz ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/Q9X1M1_THEMA Q9X1M1_THEMA]
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
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	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1wkz ConSurf].		</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1wkz ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
-	<div style="background-color:#fffaf0;">
-	== Publication Abstract from PubMed ==
-	Octaprenyl pyrophosphate synthase (OPPs) catalyzes the condensation of five isopentenyl pyrophosphates with farnesyl pyrophosphate to generate C(40) octaprenyl pyrophosphate. The enzymes from the hyperthermophilic bacterium Thermotoga maritima and from the mesophilic Escherichia coli were expressed in E. coli and the recombinant proteins were purified and crystallized. The T. maritima OPPs crystals belong to space group P42(1)2, with unit-cell parameters a = b = 151.53, c = 69.72 A. The E. coli OPPs crystals belong to space group C222(1), with unit-cell parameters a = 247.66, b = 266.10, c = 157.93 A. Diffraction data were collected at 100 K using synchrotron radiation and an in-house X-ray source. Structure determination of T. maritima OPPs has been carried out using MIR data sets at 2.8 A resolution. The asymmetric unit contains one dimer. An initial model with 280 residues per subunit has been built and refined to 2.28 A resolution. It shows mostly helical structure and resembles that of avian farnesyl pyrophosphate synthase.
-
-	Preliminary X-ray diffraction analysis of octaprenyl pyrophosphate synthase crystals from Thermotoga maritima and Escherichia coli.,Guo RT, Ko TP, Chou CC, Shr HL, Chu HM, Tsai YH, Liang PH, Wang AH Acta Crystallogr D Biol Crystallogr. 2003 Dec;59(Pt 12):2265-8. Epub 2003, Nov 27. PMID:14646090<ref>PMID:14646090</ref>
-
-	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	</div>
-	<div class="pdbe-citations 1wkz" style="background-color:#fffaf0;"></div>
-	== References ==
-	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: ~~Thema]]~~	+	[[Category: Thermotoga maritima MSB8]]
-	~~[[Category: Transferase~~]]	+	[[Category: Cheng YL]]
-	[[Category: Cheng~~, Y L~~]]	+	[[Category: Cheng YS]]
-	[[Category: Cheng~~, Y S~~]]	+	[[Category: Guo RT]]
-	[[Category: Guo~~, R T~~]]	+	[[Category: Kuo CJ]]
-	[[Category: Kuo~~, C J~~]]	+	[[Category: Liang PH]]
-	[[Category: Liang~~, P H~~]]	+	[[Category: Wang AH-J]]
-	[[Category: Wang~~, A H.~~J]]	+
-	~~[[Category: Thermophilic]]~~	+
-	~~[[Category: Trans-type prenyltransferase~~]]	+

OCA at 16:20, 27 October 2021

OCA — Wed, 27 Oct 2021 16:20:45 GMT

←Older revision		Revision as of 16:20, 27 October 2021
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	<StructureSection load='1wkz' size='340' side='right'caption='[[1wkz]], [[Resolution\|resolution]] 3.40Å' scene=''>		<StructureSection load='1wkz' size='340' side='right'caption='[[1wkz]], [[Resolution\|resolution]] 3.40Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1wkz]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Thema Thema]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WKZ OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1WKZ FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1wkz]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Thema Thema]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WKZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1WKZ FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1v4e\|1v4e]], [[1v4h\|1v4h]], [[1v4j\|1v4j]], [[1v4k\|1v4k]], [[1v4i\|1v4i]], [[1wl0\|1wl0]], [[1wl1\|1wl1]], [[1wl2\|1wl2]], [[1wl3\|1wl3]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1v4e\|1v4e]], [[1v4h\|1v4h]], [[1v4j\|1v4j]], [[1v4k\|1v4k]], [[1v4i\|1v4i]], [[1wl0\|1wl0]], [[1wl1\|1wl1]], [[1wl2\|1wl2]], [[1wl3\|1wl3]]</div></td></tr>
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://en.wikipedia.org/wiki/Transferase Transferase], with EC number [~~http~~://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.5.1.84 and 2.5.1.85 2.5.1.84 and 2.5.1.85] </span></td></tr>	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Transferase Transferase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.5.1.84 and 2.5.1.85 2.5.1.84 and 2.5.1.85] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1wkz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1wkz OCA], [~~http~~://pdbe.org/1wkz PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=1wkz RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/1wkz PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=1wkz ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1wkz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1wkz OCA], [https://pdbe.org/1wkz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1wkz RCSB], [https://www.ebi.ac.uk/pdbsum/1wkz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1wkz ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==

OCA at 17:47, 22 January 2020

OCA — Wed, 22 Jan 2020 17:47:35 GMT

←Older revision		Revision as of 17:47, 22 January 2020
Line 1:		Line 1:

	==Crystal Structure Of Octaprenyl Pyrophosphate Synthase From Hyperthermophilic Thermotoga Maritima K41A mutant==		==Crystal Structure Of Octaprenyl Pyrophosphate Synthase From Hyperthermophilic Thermotoga Maritima K41A mutant==
-	<StructureSection load='1wkz' size='340' side='right' caption='[[1wkz]], [[Resolution\|resolution]] 3.40Å' scene=''>	+	<StructureSection load='1wkz' size='340' side='right'caption='[[1wkz]], [[Resolution\|resolution]] 3.40Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1wkz]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Thema Thema]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WKZ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1WKZ FirstGlance]. <br>		<table><tr><td colspan='2'>[[1wkz]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Thema Thema]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WKZ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1WKZ FirstGlance]. <br>
Line 32:		Line 32:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Large Structures]]
	[[Category: Thema]]		[[Category: Thema]]
	[[Category: Transferase]]		[[Category: Transferase]]

OCA at 16:30, 11 April 2018

OCA — Wed, 11 Apr 2018 16:30:52 GMT

←Older revision		Revision as of 16:30, 11 April 2018
Line 1:		Line 1:
		+
	==Crystal Structure Of Octaprenyl Pyrophosphate Synthase From Hyperthermophilic Thermotoga Maritima K41A mutant==		==Crystal Structure Of Octaprenyl Pyrophosphate Synthase From Hyperthermophilic Thermotoga Maritima K41A mutant==
	<StructureSection load='1wkz' size='340' side='right' caption='[[1wkz]], [[Resolution\|resolution]] 3.40Å' scene=''>		<StructureSection load='1wkz' size='340' side='right' caption='[[1wkz]], [[Resolution\|resolution]] 3.40Å' scene=''>
Line 6:		Line 7:
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1v4e\|1v4e]], [[1v4h\|1v4h]], [[1v4j\|1v4j]], [[1v4k\|1v4k]], [[1v4i\|1v4i]], [[1wl0\|1wl0]], [[1wl1\|1wl1]], [[1wl2\|1wl2]], [[1wl3\|1wl3]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1v4e\|1v4e]], [[1v4h\|1v4h]], [[1v4j\|1v4j]], [[1v4k\|1v4k]], [[1v4i\|1v4i]], [[1wl0\|1wl0]], [[1wl1\|1wl1]], [[1wl2\|1wl2]], [[1wl3\|1wl3]]</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Transferase Transferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.5.1.84 and 2.5.1.85 2.5.1.84 and 2.5.1.85] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Transferase Transferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.5.1.84 and 2.5.1.85 2.5.1.84 and 2.5.1.85] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1wkz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1wkz OCA], [http://pdbe.org/1wkz PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1wkz RCSB], [http://www.ebi.ac.uk/pdbsum/1wkz PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1wkz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1wkz OCA], [http://pdbe.org/1wkz PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1wkz RCSB], [http://www.ebi.ac.uk/pdbsum/1wkz PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1wkz ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 12:		Line 13:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/wk/1wkz_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/wk/1wkz_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>

OCA at 13:46, 9 February 2016

OCA — Tue, 09 Feb 2016 13:46:08 GMT

←Older revision		Revision as of 13:46, 9 February 2016
Line 16:		Line 16:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1wkz ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 22:49, 10 September 2015

OCA — Thu, 10 Sep 2015 22:49:07 GMT

←Older revision		Revision as of 22:49, 10 September 2015
Line 2:		Line 2:
	<StructureSection load='1wkz' size='340' side='right' caption='[[1wkz]], [[Resolution\|resolution]] 3.40Å' scene=''>		<StructureSection load='1wkz' size='340' side='right' caption='[[1wkz]], [[Resolution\|resolution]] 3.40Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1wkz]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Thermotoga_maritima_msb8 Thermotoga maritima msb8~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WKZ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1WKZ FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1wkz]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Thema Thema]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WKZ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1WKZ FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1v4e\|1v4e]], [[1v4h\|1v4h]], [[1v4j\|1v4j]], [[1v4k\|1v4k]], [[1v4i\|1v4i]], [[1wl0\|1wl0]], [[1wl1\|1wl1]], [[1wl2\|1wl2]], [[1wl3\|1wl3]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1v4e\|1v4e]], [[1v4h\|1v4h]], [[1v4j\|1v4j]], [[1v4k\|1v4k]], [[1v4i\|1v4i]], [[1wl0\|1wl0]], [[1wl1\|1wl1]], [[1wl2\|1wl2]], [[1wl3\|1wl3]]</td></tr>
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/~~Trans-octaprenyltranstransferase Trans-octaprenyltranstransferase~~], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.5.1.11 2.5.1.11] </span></td></tr>	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Transferase Transferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.5.1.84 and 2.5.1.85 2.5.1.84 and 2.5.1.85] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1wkz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1wkz OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1wkz RCSB], [http://www.ebi.ac.uk/pdbsum/1wkz PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1wkz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1wkz OCA], [http://pdbe.org/1wkz PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1wkz RCSB], [http://www.ebi.ac.uk/pdbsum/1wkz PDBsum]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 26:		Line 26:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 1wkz" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Thermotoga maritima msb8~~]]	+	[[Category: Thema]]
-	[[Category: ~~Trans-octaprenyltranstransferase~~]]	+	[[Category: Transferase]]
	[[Category: Cheng, Y L]]		[[Category: Cheng, Y L]]
	[[Category: Cheng, Y S]]		[[Category: Cheng, Y S]]
Line 40:		Line 41:
	[[Category: Thermophilic]]		[[Category: Thermophilic]]
	[[Category: Trans-type prenyltransferase]]		[[Category: Trans-type prenyltransferase]]
-	[[Category: Transferase]]

OCA at 12:57, 6 January 2015

OCA — Tue, 06 Jan 2015 12:57:22 GMT

←Older revision		Revision as of 12:57, 6 January 2015
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1wkz]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Thermotoga_maritima_msb8 Thermotoga maritima msb8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WKZ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1WKZ FirstGlance]. <br>		<table><tr><td colspan='2'>[[1wkz]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Thermotoga_maritima_msb8 Thermotoga maritima msb8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WKZ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1WKZ FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene><br>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1v4e\|1v4e]], [[1v4h\|1v4h]], [[1v4j\|1v4j]], [[1v4k\|1v4k]], [[1v4i\|1v4i]], [[1wl0\|1wl0]], [[1wl1\|1wl1]], [[1wl2\|1wl2]], [[1wl3\|1wl3]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1v4e\|1v4e]], [[1v4h\|1v4h]], [[1v4j\|1v4j]], [[1v4k\|1v4k]], [[1v4i\|1v4i]], [[1wl0\|1wl0]], [[1wl1\|1wl1]], [[1wl2\|1wl2]], [[1wl3\|1wl3]]</td></tr>
-	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Trans-octaprenyltranstransferase Trans-octaprenyltranstransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.5.1.11 2.5.1.11] </span></td></tr>	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Trans-octaprenyltranstransferase Trans-octaprenyltranstransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.5.1.11 2.5.1.11] </span></td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1wkz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1wkz OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1wkz RCSB], [http://www.ebi.ac.uk/pdbsum/1wkz PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1wkz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1wkz OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1wkz RCSB], [http://www.ebi.ac.uk/pdbsum/1wkz PDBsum]</span></td></tr>
-	<table>	+	</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 32:		Line 32:
	[[Category: Thermotoga maritima msb8]]		[[Category: Thermotoga maritima msb8]]
	[[Category: Trans-octaprenyltranstransferase]]		[[Category: Trans-octaprenyltranstransferase]]
-	[[Category: Cheng, Y L.]]	+	[[Category: Cheng, Y L]]
-	[[Category: Cheng, Y S.]]	+	[[Category: Cheng, Y S]]
-	[[Category: Guo, R T.]]	+	[[Category: Guo, R T]]
-	[[Category: Kuo, C J.]]	+	[[Category: Kuo, C J]]
-	[[Category: Liang, P H.]]	+	[[Category: Liang, P H]]
-	[[Category: Wang, A H.J.]]	+	[[Category: Wang, A H.J]]
	[[Category: Thermophilic]]		[[Category: Thermophilic]]
	[[Category: Trans-type prenyltransferase]]		[[Category: Trans-type prenyltransferase]]
	[[Category: Transferase]]		[[Category: Transferase]]

OCA at 18:40, 29 September 2014

OCA — Mon, 29 Sep 2014 18:40:28 GMT

←Older revision		Revision as of 18:40, 29 September 2014
Line 1:		Line 1:
-	[[~~Image:~~1wkz.~~png~~\|~~left~~\|200px]]	+	==Crystal Structure Of Octaprenyl Pyrophosphate Synthase From Hyperthermophilic Thermotoga Maritima K41A mutant==
		+	<StructureSection load='1wkz' size='340' side='right' caption='[[1wkz]], [[Resolution\|resolution]] 3.40Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[1wkz]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Thermotoga_maritima_msb8 Thermotoga maritima msb8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WKZ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1WKZ FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene><br>
		+	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1v4e\|1v4e]], [[1v4h\|1v4h]], [[1v4j\|1v4j]], [[1v4k\|1v4k]], [[1v4i\|1v4i]], [[1wl0\|1wl0]], [[1wl1\|1wl1]], [[1wl2\|1wl2]], [[1wl3\|1wl3]]</td></tr>
		+	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Trans-octaprenyltranstransferase Trans-octaprenyltranstransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.5.1.11 2.5.1.11] </span></td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1wkz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1wkz OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1wkz RCSB], [http://www.ebi.ac.uk/pdbsum/1wkz PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/wk/1wkz_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Octaprenyl pyrophosphate synthase (OPPs) catalyzes the condensation of five isopentenyl pyrophosphates with farnesyl pyrophosphate to generate C(40) octaprenyl pyrophosphate. The enzymes from the hyperthermophilic bacterium Thermotoga maritima and from the mesophilic Escherichia coli were expressed in E. coli and the recombinant proteins were purified and crystallized. The T. maritima OPPs crystals belong to space group P42(1)2, with unit-cell parameters a = b = 151.53, c = 69.72 A. The E. coli OPPs crystals belong to space group C222(1), with unit-cell parameters a = 247.66, b = 266.10, c = 157.93 A. Diffraction data were collected at 100 K using synchrotron radiation and an in-house X-ray source. Structure determination of T. maritima OPPs has been carried out using MIR data sets at 2.8 A resolution. The asymmetric unit contains one dimer. An initial model with 280 residues per subunit has been built and refined to 2.28 A resolution. It shows mostly helical structure and resembles that of avian farnesyl pyrophosphate synthase.

-	~~{{STRUCTURE_1wkz\| PDB=1wkz \| SCENE= }}~~	+	Preliminary X-ray diffraction analysis of octaprenyl pyrophosphate synthase crystals from Thermotoga maritima and Escherichia coli.,Guo RT, Ko TP, Chou CC, Shr HL, Chu HM, Tsai YH, Liang PH, Wang AH Acta Crystallogr D Biol Crystallogr. 2003 Dec;59(Pt 12):2265-8. Epub 2003, Nov 27. PMID:14646090<ref>PMID:14646090</ref>

-	~~===Crystal Structure Of Octaprenyl Pyrophosphate Synthase~~ From ~~Hyperthermophilic Thermotoga Maritima K41A mutant===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_14646090}}~~	+	== References ==
-		+	<references/>
-	~~==About this Structure==~~	+	__TOC__
-	~~[[1wkz]] is~~ a ~~2 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Thermotoga_maritima_msb8 Thermotoga maritima msb8]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=1WKZ OCA].~~	+	</StructureSection>
-		+
-	==~~Reference~~==	+
-	<~~ref group="xtra">PMID:014646090<~~/~~ref~~><~~ref group="xtra">PMID:014617622</ref><ref group="xtra">PMID:015196010</ref><references group="xtra"~~/>	+
	[[Category: Thermotoga maritima msb8]]		[[Category: Thermotoga maritima msb8]]
	[[Category: Trans-octaprenyltranstransferase]]		[[Category: Trans-octaprenyltranstransferase]]

OCA at 12:21, 23 January 2013

OCA — Wed, 23 Jan 2013 12:21:10 GMT

←Older revision		Revision as of 12:21, 23 January 2013
Line 1:		Line 1:
	[[Image:1wkz.png\|left\|200px]]		[[Image:1wkz.png\|left\|200px]]

-	<!--
-	The line below this paragraph, containing "STRUCTURE_1wkz", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_1wkz\| PDB=1wkz \| SCENE= }}		{{STRUCTURE_1wkz\| PDB=1wkz \| SCENE= }}

	===Crystal Structure Of Octaprenyl Pyrophosphate Synthase From Hyperthermophilic Thermotoga Maritima K41A mutant===		===Crystal Structure Of Octaprenyl Pyrophosphate Synthase From Hyperthermophilic Thermotoga Maritima K41A mutant===

-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_14646090}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where 14646090 is the PubMed ID number.
-	-->
	{{ABSTRACT_PUBMED_14646090}}		{{ABSTRACT_PUBMED_14646090}}

Line 22:		Line 11:

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~14646090~~</ref><ref group="xtra">PMID:~~14617622~~</ref><ref group="xtra">PMID:~~15196010~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:014646090</ref><ref group="xtra">PMID:014617622</ref><ref group="xtra">PMID:015196010</ref><references group="xtra"/>
	[[Category: Thermotoga maritima msb8]]		[[Category: Thermotoga maritima msb8]]
	[[Category: Trans-octaprenyltranstransferase]]		[[Category: Trans-octaprenyltranstransferase]]
Line 33:		Line 22:
	[[Category: Thermophilic]]		[[Category: Thermophilic]]
	[[Category: Trans-type prenyltransferase]]		[[Category: Trans-type prenyltransferase]]
		+	[[Category: Transferase]]

OCA: Protected "1wkz" [edit=sysop:move=sysop]

OCA — Mon, 14 Mar 2011 18:58:26 GMT

Protected "1wkz" [edit=sysop:move=sysop]

←Older revision

Revision as of 18:58, 14 March 2011