1wni - Revision history

OCA at 13:45, 9 May 2024

OCA — Thu, 09 May 2024 13:45:30 GMT

←Older revision		Revision as of 13:45, 9 May 2024
Line 3:		Line 3:
	<StructureSection load='1wni' size='340' side='right'caption='[[1wni]], [[Resolution\|resolution]] 2.20Å' scene=''>		<StructureSection load='1wni' size='340' side='right'caption='[[1wni]], [[Resolution\|resolution]] 2.20Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1wni]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Trimeresurus_flavoviridis Trimeresurus~~ flavoviridis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WNI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1WNI FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1wni]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Protobothrops_flavoviridis Protobothrops flavoviridis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WNI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1WNI FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=ZN:ZINC+ION'>ZN</scene>~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.2Å</td></tr>
-	<tr id='~~activity~~'><td class="sblockLbl"><b>~~Activity~~:</b></td><td class="sblockDat"><~~span class~~='~~plainlinks~~'>~~[https://en.wikipedia.org/wiki/Trimerelysin_II Trimerelysin II], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.24.53 3.4.24.53]~~ </~~span~~></td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1wni FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1wni OCA], [https://pdbe.org/1wni PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1wni RCSB], [https://www.ebi.ac.uk/pdbsum/1wni PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1wni ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1wni FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1wni OCA], [https://pdbe.org/1wni PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1wni RCSB], [https://www.ebi.ac.uk/pdbsum/1wni PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1wni ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[https://www.uniprot.org/uniprot/VM1T2_PROFL VM1T2_PROFL]] Major venom non-hemorrhagic metalloproteinase.	+	[https://www.uniprot.org/uniprot/VM1T2_PROFL VM1T2_PROFL] Major venom non-hemorrhagic metalloproteinase.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 31:		Line 31:

	==See Also==		==See Also==
-	*[[Proteinase\|Proteinase]]
	*[[Proteinase 3D structures\|Proteinase 3D structures]]		*[[Proteinase 3D structures\|Proteinase 3D structures]]
	== References ==		== References ==
Line 38:		Line 37:
	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: ~~Trimerelysin II]]~~	+	[[Category: Protobothrops flavoviridis]]
-	~~[[Category: Trimeresurus~~ flavoviridis]]	+	[[Category: Iwanaga S]]
-	[[Category: Iwanaga, S]]	+	[[Category: Katsube Y]]
-	[[Category: Katsube, Y]]	+	[[Category: Kumasaka T]]
-	[[Category: Kumasaka, T]]	+	[[Category: Moriyama H]]
-	[[Category: Moriyama, H]]	+	[[Category: Omori-Satoh T]]
-	[[Category: Omori-Satoh, T]]	+	[[Category: Sato M]]
-	[[Category: Sato, M]]	+	[[Category: Tanaka N]]
-	[[Category: Tanaka, N]]	+	[[Category: Ueki T]]
-	[[Category: Ueki, T]]	+	[[Category: Yamakawa Y]]
-	[[Category: Yamakawa, Y]]	+	[[Category: Yamamoto M]]
-	[[Category: Yamamoto, M]]	+
-	~~[[Category: Hydrolase]]~~	+
-	~~[[Category: Metalloprotease]]~~	+
-	~~[[Category: Metzincin]]~~	+
-	~~[[Category: Snake venom]]~~	+
-	~~[[Category: Zinc~~]]	+

OCA at 06:30, 6 October 2021

OCA — Wed, 06 Oct 2021 06:30:22 GMT

←Older revision		Revision as of 06:30, 6 October 2021
Line 3:		Line 3:
	<StructureSection load='1wni' size='340' side='right'caption='[[1wni]], [[Resolution\|resolution]] 2.20Å' scene=''>		<StructureSection load='1wni' size='340' side='right'caption='[[1wni]], [[Resolution\|resolution]] 2.20Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1wni]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Trimeresurus_flavoviridis Trimeresurus flavoviridis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WNI OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1WNI FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1wni]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Trimeresurus_flavoviridis Trimeresurus flavoviridis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WNI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1WNI FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://en.wikipedia.org/wiki/Trimerelysin_II Trimerelysin II], with EC number [~~http~~://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.24.53 3.4.24.53] </span></td></tr>	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Trimerelysin_II Trimerelysin II], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.24.53 3.4.24.53] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1wni FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1wni OCA], [~~http~~://pdbe.org/1wni PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=1wni RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/1wni PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=1wni ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1wni FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1wni OCA], [https://pdbe.org/1wni PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1wni RCSB], [https://www.ebi.ac.uk/pdbsum/1wni PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1wni ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[~~http~~://www.uniprot.org/uniprot/VM1T2_PROFL VM1T2_PROFL]] Major venom non-hemorrhagic metalloproteinase.	+	[[https://www.uniprot.org/uniprot/VM1T2_PROFL VM1T2_PROFL]] Major venom non-hemorrhagic metalloproteinase.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 32:		Line 32:
	==See Also==		==See Also==
	*[[Proteinase\|Proteinase]]		*[[Proteinase\|Proteinase]]
		+	*[[Proteinase 3D structures\|Proteinase 3D structures]]
	== References ==		== References ==
	<references/>		<references/>

OCA at 05:35, 10 October 2019

OCA — Thu, 10 Oct 2019 05:35:02 GMT

←Older revision		Revision as of 05:35, 10 October 2019
Line 1:		Line 1:

	==Crystal Structure of H2-Proteinase==		==Crystal Structure of H2-Proteinase==
-	<StructureSection load='1wni' size='340' side='right' caption='[[1wni]], [[Resolution\|resolution]] 2.20Å' scene=''>	+	<StructureSection load='1wni' size='340' side='right'caption='[[1wni]], [[Resolution\|resolution]] 2.20Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1wni]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Trimeresurus_flavoviridis Trimeresurus flavoviridis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WNI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1WNI FirstGlance]. <br>		<table><tr><td colspan='2'>[[1wni]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Trimeresurus_flavoviridis Trimeresurus flavoviridis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WNI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1WNI FirstGlance]. <br>
Line 36:		Line 36:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Large Structures]]
	[[Category: Trimerelysin II]]		[[Category: Trimerelysin II]]
	[[Category: Trimeresurus flavoviridis]]		[[Category: Trimeresurus flavoviridis]]

OCA at 16:00, 11 April 2018

OCA — Wed, 11 Apr 2018 16:00:39 GMT

←Older revision		Revision as of 16:00, 11 April 2018
Line 1:		Line 1:
		+
	==Crystal Structure of H2-Proteinase==		==Crystal Structure of H2-Proteinase==
	<StructureSection load='1wni' size='340' side='right' caption='[[1wni]], [[Resolution\|resolution]] 2.20Å' scene=''>		<StructureSection load='1wni' size='340' side='right' caption='[[1wni]], [[Resolution\|resolution]] 2.20Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1wni]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Protobothrops_flavoviridis Protobothrops~~ flavoviridis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WNI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1WNI FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1wni]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Trimeresurus_flavoviridis Trimeresurus flavoviridis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WNI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1WNI FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Trimerelysin_II Trimerelysin II], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.24.53 3.4.24.53] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Trimerelysin_II Trimerelysin II], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.24.53 3.4.24.53] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1wni FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1wni OCA], [http://pdbe.org/1wni PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1wni RCSB], [http://www.ebi.ac.uk/pdbsum/1wni PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1wni FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1wni OCA], [http://pdbe.org/1wni PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1wni RCSB], [http://www.ebi.ac.uk/pdbsum/1wni PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1wni ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 13:		Line 14:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/wn/1wni_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/wn/1wni_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
Line 35:		Line 36:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Protobothrops flavoviridis]]
	[[Category: Trimerelysin II]]		[[Category: Trimerelysin II]]
		+	[[Category: Trimeresurus flavoviridis]]
	[[Category: Iwanaga, S]]		[[Category: Iwanaga, S]]
	[[Category: Katsube, Y]]		[[Category: Katsube, Y]]
Line 51:		Line 52:
	[[Category: Metzincin]]		[[Category: Metzincin]]
	[[Category: Snake venom]]		[[Category: Snake venom]]
		+	[[Category: Zinc]]

OCA at 19:59, 9 February 2016

OCA — Tue, 09 Feb 2016 19:59:04 GMT

←Older revision		Revision as of 19:59, 9 February 2016
Line 17:		Line 17:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1wni ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 01:33, 11 September 2015

OCA — Fri, 11 Sep 2015 01:33:03 GMT

←Older revision		Revision as of 01:33, 11 September 2015
Line 2:		Line 2:
	<StructureSection load='1wni' size='340' side='right' caption='[[1wni]], [[Resolution\|resolution]] 2.20Å' scene=''>		<StructureSection load='1wni' size='340' side='right' caption='[[1wni]], [[Resolution\|resolution]] 2.20Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1wni]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Trimeresurus_flavoviridis Trimeresurus~~ flavoviridis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WNI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1WNI FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1wni]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Protobothrops_flavoviridis Protobothrops flavoviridis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WNI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1WNI FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Trimerelysin_II Trimerelysin II], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.24.53 3.4.24.53] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Trimerelysin_II Trimerelysin II], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.24.53 3.4.24.53] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1wni FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1wni OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1wni RCSB], [http://www.ebi.ac.uk/pdbsum/1wni PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1wni FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1wni OCA], [http://pdbe.org/1wni PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1wni RCSB], [http://www.ebi.ac.uk/pdbsum/1wni PDBsum]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[http://www.uniprot.org/uniprot/~~HR2_TRIFL HR2_TRIFL~~]] Major venom non-hemorrhagic metalloproteinase.	+	[[http://www.uniprot.org/uniprot/VM1T2_PROFL VM1T2_PROFL]] Major venom non-hemorrhagic metalloproteinase.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 27:		Line 27:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 1wni" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
Line 34:		Line 35:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Protobothrops flavoviridis]]
	[[Category: Trimerelysin II]]		[[Category: Trimerelysin II]]
-	[[Category: Trimeresurus flavoviridis]]
	[[Category: Iwanaga, S]]		[[Category: Iwanaga, S]]
	[[Category: Katsube, Y]]		[[Category: Katsube, Y]]

OCA at 09:11, 25 December 2014

OCA — Thu, 25 Dec 2014 09:11:02 GMT

←Older revision		Revision as of 09:11, 25 December 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1wni]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Trimeresurus_flavoviridis Trimeresurus flavoviridis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WNI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1WNI FirstGlance]. <br>		<table><tr><td colspan='2'>[[1wni]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Trimeresurus_flavoviridis Trimeresurus flavoviridis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WNI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1WNI FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene><br>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
-	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Trimerelysin_II Trimerelysin II], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.24.53 3.4.24.53] </span></td></tr>	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Trimerelysin_II Trimerelysin II], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.24.53 3.4.24.53] </span></td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1wni FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1wni OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1wni RCSB], [http://www.ebi.ac.uk/pdbsum/1wni PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1wni FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1wni OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1wni RCSB], [http://www.ebi.ac.uk/pdbsum/1wni PDBsum]</span></td></tr>
-	<table>	+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/HR2_TRIFL HR2_TRIFL]] Major venom non-hemorrhagic metalloproteinase.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 34:		Line 36:
	[[Category: Trimerelysin II]]		[[Category: Trimerelysin II]]
	[[Category: Trimeresurus flavoviridis]]		[[Category: Trimeresurus flavoviridis]]
-	[[Category: Iwanaga, S.]]	+	[[Category: Iwanaga, S]]
-	[[Category: Katsube, Y.]]	+	[[Category: Katsube, Y]]
-	[[Category: Kumasaka, T.]]	+	[[Category: Kumasaka, T]]
-	[[Category: Moriyama, H.]]	+	[[Category: Moriyama, H]]
-	[[Category: Omori-Satoh, T.]]	+	[[Category: Omori-Satoh, T]]
-	[[Category: Sato, M.]]	+	[[Category: Sato, M]]
-	[[Category: Tanaka, N.]]	+	[[Category: Tanaka, N]]
-	[[Category: Ueki, T.]]	+	[[Category: Ueki, T]]
-	[[Category: Yamakawa, Y.]]	+	[[Category: Yamakawa, Y]]
-	[[Category: Yamamoto, M.]]	+	[[Category: Yamamoto, M]]
	[[Category: Hydrolase]]		[[Category: Hydrolase]]
	[[Category: Metalloprotease]]		[[Category: Metalloprotease]]
	[[Category: Metzincin]]		[[Category: Metzincin]]
	[[Category: Snake venom]]		[[Category: Snake venom]]

OCA at 20:18, 29 September 2014

OCA — Mon, 29 Sep 2014 20:18:30 GMT

←Older revision		Revision as of 20:18, 29 September 2014
Line 1:		Line 1:
-	[[~~Image~~:1wni.~~png\|left~~\|200px]]	+	==Crystal Structure of H2-Proteinase==
		+	<StructureSection load='1wni' size='340' side='right' caption='[[1wni]], [[Resolution\|resolution]] 2.20Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[1wni]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Trimeresurus_flavoviridis Trimeresurus flavoviridis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WNI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1WNI FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene><br>
		+	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Trimerelysin_II Trimerelysin II], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.24.53 3.4.24.53] </span></td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1wni FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1wni OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1wni RCSB], [http://www.ebi.ac.uk/pdbsum/1wni PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/wn/1wni_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	The crystal structure of the zinc-protease, H2-proteinase, isolated from the venom of Trimeresurus flavoviridis has been determined. The crystallographic R factor is 0.176 for 10,635 reflections with Fobs > 2sigma(Fobs) in the 8.0 to 2.2 Angstrom resolution range. The enzyme has two domains with a cleft in which a catalytic zinc atom is located. The N-terminal domain is composed of four helices around a central five-stranded beta-sheet. The irregularly folded C-terminal domain contains one helix and two disulfide bridges. These two domains are linked by a disulfide bridge. In the zinc environment, the catalytic zinc atom forms a distorted tetrahedral coordination with three histidines and one catalytic water molecule, and the methionine-containing turn is structurally conserved. These are distinctive features of the metzincins, one of the zinc metalloprotease superfamilies. The entire structure shows good agreement with that of two Crotalus snake venom proteases, adamalysin II and atrolysin C. The H2-proteinase, however, contains no structural calcium ions, and differences of disulfide configurations and the coordination of the catalytic water molecule exist as compared with the other two proteases.

-	~~{{STRUCTURE_1wni\| PDB=1wni \| SCENE= }}~~	+	Crystal structure of H2-proteinase from the venom of Trimeresurus flavoviridis.,Kumasaka T, Yamamoto M, Moriyama H, Tanaka N, Sato M, Katsube Y, Yamakawa Y, Omori-Satoh T, Iwanaga S, Ueki T J Biochem. 1996 Jan;119(1):49-57. PMID:8907175<ref>PMID:8907175</ref>

-	~~===Crystal Structure~~ of ~~H2-Proteinase===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>

-	~~{{ABSTRACT_PUBMED_8907175}}~~	+	==See Also==
-		+	*[[Proteinase\|Proteinase]]
-	==~~About this Structure~~==	+	== References ==
-	[[~~1wni~~]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Trimeresurus_flavoviridis Trimeresurus flavoviridis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WNI OCA].	+	<references/>
-		+	__TOC__
-	==~~Reference~~==	+	</StructureSection>
-	<~~ref group="xtra">PMID:008907175<~~/~~ref~~><~~references group="xtra"~~/>	+
	[[Category: Trimerelysin II]]		[[Category: Trimerelysin II]]
	[[Category: Trimeresurus flavoviridis]]		[[Category: Trimeresurus flavoviridis]]

OCA at 12:15, 23 January 2013

OCA — Wed, 23 Jan 2013 12:15:20 GMT

←Older revision		Revision as of 12:15, 23 January 2013
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	[[Image:1wni.png\|left\|200px]]		[[Image:1wni.png\|left\|200px]]

-	<!--
-	The line below this paragraph, containing "STRUCTURE_1wni", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_1wni\| PDB=1wni \| SCENE= }}		{{STRUCTURE_1wni\| PDB=1wni \| SCENE= }}

	===Crystal Structure of H2-Proteinase===		===Crystal Structure of H2-Proteinase===

-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_8907175}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where 8907175 is the PubMed ID number.
-	-->
	{{ABSTRACT_PUBMED_8907175}}		{{ABSTRACT_PUBMED_8907175}}

Line 22:		Line 11:

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~8907175</ref><ref group="xtra">PMID:8586633~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:008907175</ref><references group="xtra"/>
	[[Category: Trimerelysin II]]		[[Category: Trimerelysin II]]
	[[Category: Trimeresurus flavoviridis]]		[[Category: Trimeresurus flavoviridis]]
Line 39:		Line 28:
	[[Category: Metzincin]]		[[Category: Metzincin]]
	[[Category: Snake venom]]		[[Category: Snake venom]]
-	[[Category: Zinc]]

OCA: Protected "1wni" [edit=sysop:move=sysop]

OCA — Mon, 14 Mar 2011 12:45:18 GMT

Protected "1wni" [edit=sysop:move=sysop]

←Older revision

Revision as of 12:45, 14 March 2011