1wud - Revision history

OCA at 13:49, 9 May 2024

OCA — Thu, 09 May 2024 13:49:56 GMT

←Older revision		Revision as of 13:49, 9 May 2024
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	<StructureSection load='1wud' size='340' side='right'caption='[[1wud]], [[Resolution\|resolution]] 2.20Å' scene=''>		<StructureSection load='1wud' size='340' side='right'caption='[[1wud]], [[Resolution\|resolution]] 2.20Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1wud]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/~~"bacillus_coli"_migula_1895 "bacillus~~ coli~~" migula 1895~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WUD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1WUD FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1wud]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WUD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1WUD FirstGlance]. <br>
-	</td></tr><tr id='~~NonStdRes~~'><td class="sblockLbl"><b>[[~~Non~~-~~Standard_Residue~~\|~~NonStd Res~~:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.2Å</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1wud FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1wud OCA], [https://pdbe.org/1wud PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1wud RCSB], [https://www.ebi.ac.uk/pdbsum/1wud PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1wud ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1wud FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1wud OCA], [https://pdbe.org/1wud PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1wud RCSB], [https://www.ebi.ac.uk/pdbsum/1wud PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1wud ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[https://www.uniprot.org/uniprot/RECQ_ECOLI RECQ_ECOLI]] Involved in the RecF recombination pathway; its gene expression is under the regulation of the SOS system. It is a DNA helicase.	+	[https://www.uniprot.org/uniprot/RECQ_ECOLI RECQ_ECOLI] Involved in the RecF recombination pathway; its gene expression is under the regulation of the SOS system. It is a DNA helicase.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 35:		Line 36:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Bacillus~~ coli ~~migula 1895~~]]	+	[[Category: Escherichia coli]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Bernstein~~, D A~~]]	+	[[Category: Bernstein DA]]
-	[[Category: Keck~~, J L]]~~	+	[[Category: Keck JL]]
-	~~[[Category: Dna-binding domain]]~~	+
-	~~[[Category: Helicase]]~~	+
-	~~[[Category: Hrdc]]~~	+
-	~~[[Category: Hydrolase]]~~	+
-	~~[[Category: Recq~~]]	+

OCA at 16:27, 27 October 2021

OCA — Wed, 27 Oct 2021 16:27:33 GMT

←Older revision		Revision as of 16:27, 27 October 2021
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	<StructureSection load='1wud' size='340' side='right'caption='[[1wud]], [[Resolution\|resolution]] 2.20Å' scene=''>		<StructureSection load='1wud' size='340' side='right'caption='[[1wud]], [[Resolution\|resolution]] 2.20Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1wud]] is a 3 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WUD OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1WUD FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1wud]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WUD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1WUD FirstGlance]. <br>
	</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>		</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1wud FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1wud OCA], [~~http~~://pdbe.org/1wud PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=1wud RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/1wud PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=1wud ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1wud FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1wud OCA], [https://pdbe.org/1wud PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1wud RCSB], [https://www.ebi.ac.uk/pdbsum/1wud PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1wud ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[~~http~~://www.uniprot.org/uniprot/RECQ_ECOLI RECQ_ECOLI]] Involved in the RecF recombination pathway; its gene expression is under the regulation of the SOS system. It is a DNA helicase.	+	[[https://www.uniprot.org/uniprot/RECQ_ECOLI RECQ_ECOLI]] Involved in the RecF recombination pathway; its gene expression is under the regulation of the SOS system. It is a DNA helicase.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]

OCA at 17:29, 22 January 2020

OCA — Wed, 22 Jan 2020 17:29:34 GMT

←Older revision		Revision as of 17:29, 22 January 2020
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	==E. coli RecQ HRDC domain==		==E. coli RecQ HRDC domain==
-	<StructureSection load='1wud' size='340' side='right' caption='[[1wud]], [[Resolution\|resolution]] 2.20Å' scene=''>	+	<StructureSection load='1wud' size='340' side='right'caption='[[1wud]], [[Resolution\|resolution]] 2.20Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1wud]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WUD OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1WUD FirstGlance]. <br>		<table><tr><td colspan='2'>[[1wud]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WUD OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1WUD FirstGlance]. <br>
Line 30:		Line 30:

	==See Also==		==See Also==
-	*[[Helicase\|Helicase]]	+	*[[Helicase 3D structures\|Helicase 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
Line 36:		Line 36:
	</StructureSection>		</StructureSection>
	[[Category: Bacillus coli migula 1895]]		[[Category: Bacillus coli migula 1895]]
		+	[[Category: Large Structures]]
	[[Category: Bernstein, D A]]		[[Category: Bernstein, D A]]
	[[Category: Keck, J L]]		[[Category: Keck, J L]]

OCA at 16:15, 11 April 2018

OCA — Wed, 11 Apr 2018 16:15:13 GMT

←Older revision		Revision as of 16:15, 11 April 2018
Line 1:		Line 1:
		+
	==E. coli RecQ HRDC domain==		==E. coli RecQ HRDC domain==
	<StructureSection load='1wud' size='340' side='right' caption='[[1wud]], [[Resolution\|resolution]] 2.20Å' scene=''>		<StructureSection load='1wud' size='340' side='right' caption='[[1wud]], [[Resolution\|resolution]] 2.20Å' scene=''>
Line 4:		Line 5:
	<table><tr><td colspan='2'>[[1wud]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WUD OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1WUD FirstGlance]. <br>		<table><tr><td colspan='2'>[[1wud]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WUD OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1WUD FirstGlance]. <br>
	</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>		</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1wud FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1wud OCA], [http://pdbe.org/1wud PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1wud RCSB], [http://www.ebi.ac.uk/pdbsum/1wud PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1wud FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1wud OCA], [http://pdbe.org/1wud PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1wud RCSB], [http://www.ebi.ac.uk/pdbsum/1wud PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1wud ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 12:		Line 13:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/wu/1wud_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/wu/1wud_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>

OCA at 11:19, 8 February 2016

OCA — Mon, 08 Feb 2016 11:19:12 GMT

←Older revision		Revision as of 11:19, 8 February 2016
Line 16:		Line 16:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1wud ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 11:02, 10 September 2015

OCA — Thu, 10 Sep 2015 11:02:08 GMT

←Older revision		Revision as of 11:02, 10 September 2015
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	<StructureSection load='1wud' size='340' side='right' caption='[[1wud]], [[Resolution\|resolution]] 2.20Å' scene=''>		<StructureSection load='1wud' size='340' side='right' caption='[[1wud]], [[Resolution\|resolution]] 2.20Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1wud]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Escherichia_coli Escherichia~~ coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WUD OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1WUD FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1wud]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WUD OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1WUD FirstGlance]. <br>
	</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>		</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1wud FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1wud OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1wud RCSB], [http://www.ebi.ac.uk/pdbsum/1wud PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1wud FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1wud OCA], [http://pdbe.org/1wud PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1wud RCSB], [http://www.ebi.ac.uk/pdbsum/1wud PDBsum]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 26:		Line 26:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 1wud" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
Line 33:		Line 34:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Escherichia~~ coli]]	+	[[Category: Bacillus coli migula 1895]]
	[[Category: Bernstein, D A]]		[[Category: Bernstein, D A]]
	[[Category: Keck, J L]]		[[Category: Keck, J L]]

OCA at 22:56, 24 December 2014

OCA — Wed, 24 Dec 2014 22:56:32 GMT

←Older revision		Revision as of 22:56, 24 December 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1wud]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WUD OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1WUD FirstGlance]. <br>		<table><tr><td colspan='2'>[[1wud]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WUD OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1WUD FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>	+	</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1wud FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1wud OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1wud RCSB], [http://www.ebi.ac.uk/pdbsum/1wud PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1wud FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1wud OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1wud RCSB], [http://www.ebi.ac.uk/pdbsum/1wud PDBsum]</span></td></tr>
-	<table>	+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/RECQ_ECOLI RECQ_ECOLI]] Involved in the RecF recombination pathway; its gene expression is under the regulation of the SOS system. It is a DNA helicase.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 32:		Line 34:
	</StructureSection>		</StructureSection>
	[[Category: Escherichia coli]]		[[Category: Escherichia coli]]
-	[[Category: Bernstein, D A.]]	+	[[Category: Bernstein, D A]]
-	[[Category: Keck, J L.]]	+	[[Category: Keck, J L]]
	[[Category: Dna-binding domain]]		[[Category: Dna-binding domain]]
	[[Category: Helicase]]		[[Category: Helicase]]

OCA at 20:17, 28 September 2014

OCA — Sun, 28 Sep 2014 20:17:56 GMT

←Older revision		Revision as of 20:17, 28 September 2014
Line 1:		Line 1:
-	[[~~Image~~:1wud.~~png\|left~~\|200px]]	+	==E. coli RecQ HRDC domain==
		+	<StructureSection load='1wud' size='340' side='right' caption='[[1wud]], [[Resolution\|resolution]] 2.20Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[1wud]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WUD OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1WUD FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1wud FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1wud OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1wud RCSB], [http://www.ebi.ac.uk/pdbsum/1wud PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/wu/1wud_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	RecQ DNA helicases are multidomain enzymes that play pivotal roles in genome maintenance pathways. While the ATPase and helicase activities of these enzymes can be attributed to the conserved catalytic core domain, the role of the Helicase-and-RNase-D-C-terminal (HRDC) domain in RecQ function has yet to be elucidated. Here, we report the crystal structure of the E. coli RecQ HRDC domain, revealing a globular fold that resembles known DNA binding domains. We show that this domain preferentially binds single-stranded DNA and identify its DNA binding surface. HRDC domain mutations in full-length RecQ lead to surprising differences in its structure-specific DNA binding properties. These data support a model in which naturally occurring variations in DNA binding residues among diverse RecQ homologs serve to target these enzymes to distinct substrates and provide insight into a mechanism whereby RecQ enzymes have evolved distinct functions in organisms that encode multiple recQ genes.

-	~~{{STRUCTURE_1wud\| PDB=1wud \| SCENE= }}~~	+	Conferring substrate specificity to DNA helicases: role of the RecQ HRDC domain.,Bernstein DA, Keck JL Structure. 2005 Aug;13(8):1173-82. PMID:16084389<ref>PMID:16084389</ref>

-	~~===E. coli RecQ HRDC domain===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_16084389}}~~	+
-		+
-	~~==About this Structure==~~	+
-	~~[[1wud]] is~~ a ~~3 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Escherichia_coli Escherichia coli]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=1WUD OCA].~~	+

	==See Also==		==See Also==
	*[[Helicase\|Helicase]]		*[[Helicase\|Helicase]]
-		+	== References ==
-	==~~Reference~~==	+	<references/>
-	<~~ref group="xtra">PMID:016084389<~~/~~ref~~><~~references group="xtra"~~/>	+	__TOC__
		+	</StructureSection>
	[[Category: Escherichia coli]]		[[Category: Escherichia coli]]
	[[Category: Bernstein, D A.]]		[[Category: Bernstein, D A.]]

OCA at 09:58, 20 October 2012

OCA — Sat, 20 Oct 2012 09:58:21 GMT

←Older revision		Revision as of 09:58, 20 October 2012
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	==About this Structure==		==About this Structure==
-	[[1wud]] is a 3 chain structure ~~of [[Helicase]]~~ with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WUD OCA].	+	[[1wud]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WUD OCA].

	==See Also==		==See Also==

OCA: Protected "1wud" [edit=sysop:move=sysop]

OCA — Thu, 26 Jul 2012 00:34:07 GMT

Protected "1wud" [edit=sysop:move=sysop]

←Older revision

Revision as of 00:34, 26 July 2012