1wxw - Revision history

OCA at 13:53, 9 May 2024

OCA — Thu, 09 May 2024 13:53:32 GMT

←Older revision		Revision as of 13:53, 9 May 2024
Line 3:		Line 3:
	<StructureSection load='1wxw' size='340' side='right'caption='[[1wxw]], [[Resolution\|resolution]] 2.55Å' scene=''>		<StructureSection load='1wxw' size='340' side='right'caption='[[1wxw]], [[Resolution\|resolution]] 2.55Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1wxw]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Thet8 Thet8~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WXW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1WXW FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1wxw]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermus_thermophilus_HB8 Thermus thermophilus HB8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WXW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1WXW FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=HEZ:HEXANE~~-1,~~6-DIOL'>HEZ</scene>~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.55Å</td></tr>
-	<tr id='~~NonStdRes~~'><td class="sblockLbl"><b>[[~~Non-Standard_Residue~~\|~~NonStd Res~~:]]</b></td><td class="sblockDat"><scene name='pdbligand=~~MSE~~:~~SELENOMETHIONINE~~'>~~MSE~~</scene><~~/td></tr>~~	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=HEZ:HEXANE-1,6-DIOL'>HEZ</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
-	~~<tr id~~='~~related'><td class~~=~~"sblockLbl"><b>[[Related_structure\|Related~~:~~]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;~~'>~~[[1wxx\|1wxx]]~~</~~div~~></td></tr>	+
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1wxw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1wxw OCA], [https://pdbe.org/1wxw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1wxw RCSB], [https://www.ebi.ac.uk/pdbsum/1wxw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1wxw ProSAT], [https://www.topsan.org/Proteins/RSGI/1wxw TOPSAN]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1wxw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1wxw OCA], [https://pdbe.org/1wxw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1wxw RCSB], [https://www.ebi.ac.uk/pdbsum/1wxw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1wxw ProSAT], [https://www.topsan.org/Proteins/RSGI/1wxw TOPSAN]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/Q5SIT4_THET8 Q5SIT4_THET8]
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 33:		Line 34:
	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: ~~Thet8~~]]	+	[[Category: Thermus thermophilus HB8]]
-	[[Category: Ebihara, A]]	+	[[Category: Ebihara A]]
-	[[Category: Kuramitsu, S]]	+	[[Category: Kuramitsu S]]
-	[[Category: Murayama, K]]	+	[[Category: Murayama K]]
-	[[Category: Nakagawa, N]]	+	[[Category: Nakagawa N]]
-	[[Category: Pioszak~~, A A]]~~	+	[[Category: Pioszak AA]]
-	~~[[Category: Structural genomic~~]]	+	[[Category: Shirouzu M]]
-	[[Category: Shirouzu, M]]	+	[[Category: Yokoyama S]]
-	[[Category: Yokoyama, S]]	+
-	~~[[Category: Adomet]]~~	+
-	~~[[Category: Methyltransferase]]~~	+
-	~~[[Category: National project on protein structural and functional analyse]]~~	+
-	~~[[Category: Nppsfa]]~~	+
-	~~[[Category: Rsgi]]~~	+
-	~~[[Category: Thermus thermophillus]]~~	+
-	~~[[Category: Transferase~~]]	+

OCA at 16:30, 27 October 2021

OCA — Wed, 27 Oct 2021 16:30:15 GMT

←Older revision		Revision as of 16:30, 27 October 2021
Line 3:		Line 3:
	<StructureSection load='1wxw' size='340' side='right'caption='[[1wxw]], [[Resolution\|resolution]] 2.55Å' scene=''>		<StructureSection load='1wxw' size='340' side='right'caption='[[1wxw]], [[Resolution\|resolution]] 2.55Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1wxw]] is a 4 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Thet8 Thet8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WXW OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1WXW FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1wxw]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Thet8 Thet8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WXW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1WXW FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=HEZ:HEXANE-1,6-DIOL'>HEZ</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=HEZ:HEXANE-1,6-DIOL'>HEZ</scene></td></tr>
	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>		<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1wxx\|1wxx]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1wxx\|1wxx]]</div></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1wxw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1wxw OCA], [~~http~~://pdbe.org/1wxw PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=1wxw RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/1wxw PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=1wxw ProSAT], [~~http~~://www.topsan.org/Proteins/RSGI/1wxw TOPSAN]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1wxw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1wxw OCA], [https://pdbe.org/1wxw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1wxw RCSB], [https://www.ebi.ac.uk/pdbsum/1wxw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1wxw ProSAT], [https://www.topsan.org/Proteins/RSGI/1wxw TOPSAN]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==

OCA at 17:41, 22 January 2020

OCA — Wed, 22 Jan 2020 17:41:35 GMT

←Older revision		Revision as of 17:41, 22 January 2020
Line 1:		Line 1:

	==Crystal structure of Tt1595, a putative SAM-dependent methyltransferase from Thermus thermophillus HB8==		==Crystal structure of Tt1595, a putative SAM-dependent methyltransferase from Thermus thermophillus HB8==
-	<StructureSection load='1wxw' size='340' side='right' caption='[[1wxw]], [[Resolution\|resolution]] 2.55Å' scene=''>	+	<StructureSection load='1wxw' size='340' side='right'caption='[[1wxw]], [[Resolution\|resolution]] 2.55Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1wxw]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Thet8 Thet8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WXW OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1WXW FirstGlance]. <br>		<table><tr><td colspan='2'>[[1wxw]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Thet8 Thet8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WXW OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1WXW FirstGlance]. <br>
Line 32:		Line 32:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Large Structures]]
	[[Category: Thet8]]		[[Category: Thet8]]
	[[Category: Ebihara, A]]		[[Category: Ebihara, A]]

OCA at 16:26, 11 April 2018

OCA — Wed, 11 Apr 2018 16:26:03 GMT

←Older revision		Revision as of 16:26, 11 April 2018
Line 1:		Line 1:
		+
	==Crystal structure of Tt1595, a putative SAM-dependent methyltransferase from Thermus thermophillus HB8==		==Crystal structure of Tt1595, a putative SAM-dependent methyltransferase from Thermus thermophillus HB8==
	<StructureSection load='1wxw' size='340' side='right' caption='[[1wxw]], [[Resolution\|resolution]] 2.55Å' scene=''>		<StructureSection load='1wxw' size='340' side='right' caption='[[1wxw]], [[Resolution\|resolution]] 2.55Å' scene=''>
Line 6:		Line 7:
	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>		<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1wxx\|1wxx]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1wxx\|1wxx]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1wxw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1wxw OCA], [http://pdbe.org/1wxw PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1wxw RCSB], [http://www.ebi.ac.uk/pdbsum/1wxw PDBsum], [http://www.topsan.org/Proteins/RSGI/1wxw TOPSAN]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1wxw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1wxw OCA], [http://pdbe.org/1wxw PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1wxw RCSB], [http://www.ebi.ac.uk/pdbsum/1wxw PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1wxw ProSAT], [http://www.topsan.org/Proteins/RSGI/1wxw TOPSAN]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 12:		Line 13:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/wx/1wxw_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/wx/1wxw_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1wxw ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 02:26, 12 September 2015

OCA — Sat, 12 Sep 2015 02:26:35 GMT

←Older revision		Revision as of 02:26, 12 September 2015
Line 2:		Line 2:
	<StructureSection load='1wxw' size='340' side='right' caption='[[1wxw]], [[Resolution\|resolution]] 2.55Å' scene=''>		<StructureSection load='1wxw' size='340' side='right' caption='[[1wxw]], [[Resolution\|resolution]] 2.55Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1wxw]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Thermus_thermophilus Thermus thermophilus~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WXW OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1WXW FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1wxw]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Thet8 Thet8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WXW OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1WXW FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=HEZ:HEXANE-1,6-DIOL'>HEZ</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=HEZ:HEXANE-1,6-DIOL'>HEZ</scene></td></tr>
	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>		<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1wxx\|1wxx]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1wxx\|1wxx]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1wxw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1wxw OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1wxw RCSB], [http://www.ebi.ac.uk/pdbsum/1wxw PDBsum], [http://www.topsan.org/Proteins/RSGI/1wxw TOPSAN]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1wxw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1wxw OCA], [http://pdbe.org/1wxw PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1wxw RCSB], [http://www.ebi.ac.uk/pdbsum/1wxw PDBsum], [http://www.topsan.org/Proteins/RSGI/1wxw TOPSAN]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 26:		Line 26:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 1wxw" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Thermus thermophilus~~]]	+	[[Category: Thet8]]
	[[Category: Ebihara, A]]		[[Category: Ebihara, A]]
	[[Category: Kuramitsu, S]]		[[Category: Kuramitsu, S]]

OCA at 13:46, 6 January 2015

OCA — Tue, 06 Jan 2015 13:46:41 GMT

←Older revision		Revision as of 13:46, 6 January 2015
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1wxw]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WXW OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1WXW FirstGlance]. <br>		<table><tr><td colspan='2'>[[1wxw]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WXW OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1WXW FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=HEZ:HEXANE-1,6-DIOL'>HEZ</scene><br>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=HEZ:HEXANE-1,6-DIOL'>HEZ</scene></td></tr>
-	<tr><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>	+	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
-	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1wxx\|1wxx]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1wxx\|1wxx]]</td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1wxw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1wxw OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1wxw RCSB], [http://www.ebi.ac.uk/pdbsum/1wxw PDBsum], [http://www.topsan.org/Proteins/RSGI/1wxw TOPSAN]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1wxw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1wxw OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1wxw RCSB], [http://www.ebi.ac.uk/pdbsum/1wxw PDBsum], [http://www.topsan.org/Proteins/RSGI/1wxw TOPSAN]</span></td></tr>
-	<table>	+	</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 31:		Line 31:
	</StructureSection>		</StructureSection>
	[[Category: Thermus thermophilus]]		[[Category: Thermus thermophilus]]
-	[[Category: Ebihara, A.]]	+	[[Category: Ebihara, A]]
-	[[Category: Kuramitsu, S.]]	+	[[Category: Kuramitsu, S]]
-	[[Category: Murayama, K.]]	+	[[Category: Murayama, K]]
-	[[Category: Nakagawa, N.]]	+	[[Category: Nakagawa, N]]
-	[[Category: Pioszak, A A.]]	+	[[Category: Pioszak, A A]]
-	[[Category: ~~RSGI, RIKEN~~ Structural ~~Genomics/Proteomics Initiative.~~]]	+	[[Category: Structural genomic]]
-	[[Category: Shirouzu, M.]]	+	[[Category: Shirouzu, M]]
-	[[Category: Yokoyama, S.]]	+	[[Category: Yokoyama, S]]
	[[Category: Adomet]]		[[Category: Adomet]]
	[[Category: Methyltransferase]]		[[Category: Methyltransferase]]
	[[Category: National project on protein structural and functional analyse]]		[[Category: National project on protein structural and functional analyse]]
	[[Category: Nppsfa]]		[[Category: Nppsfa]]
-	[[Category: Riken structural genomics/proteomics initiative]]
	[[Category: Rsgi]]		[[Category: Rsgi]]
-	[[Category: Structural genomic]]
	[[Category: Thermus thermophillus]]		[[Category: Thermus thermophillus]]
	[[Category: Transferase]]		[[Category: Transferase]]

OCA at 21:57, 29 September 2014

OCA — Mon, 29 Sep 2014 21:57:49 GMT

←Older revision		Revision as of 21:57, 29 September 2014
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-	[[~~Image:~~1wxw.~~png~~\|~~left~~\|200px]]	+	==Crystal structure of Tt1595, a putative SAM-dependent methyltransferase from Thermus thermophillus HB8==
		+	<StructureSection load='1wxw' size='340' side='right' caption='[[1wxw]], [[Resolution\|resolution]] 2.55Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[1wxw]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WXW OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1WXW FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=HEZ:HEXANE-1,6-DIOL'>HEZ</scene><br>
		+	<tr><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
		+	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1wxx\|1wxx]]</td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1wxw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1wxw OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1wxw RCSB], [http://www.ebi.ac.uk/pdbsum/1wxw PDBsum], [http://www.topsan.org/Proteins/RSGI/1wxw TOPSAN]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/wx/1wxw_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	The Thermus thermophilus hypothetical protein TTHA1280 belongs to a family of predicted S-adenosyl-L-methionine (AdoMet) dependent RNA methyltransferases (MTases) present in many bacterial and archaeal species. Inspection of amino-acid sequence motifs common to class I Rossmann-fold-like MTases suggested a specific role as an RNA 5-methyluridine MTase. Selenomethionine (SeMet) labelled and native versions of the protein were expressed, purified and crystallized. Two crystal forms of the SeMet-labelled apoprotein were obtained: SeMet-ApoI and SeMet-ApoII. Cocrystallization of the native protein with S-adenosyl-L-homocysteine (AdoHcy) yielded a third crystal form, Native-AdoHcy. The SeMet-ApoI structure was solved by the multiple anomalous dispersion method and refined at 2.55 A resolution. The SeMet-ApoII and Native-AdoHcy structures were solved by molecular replacement and refined at 1.80 and 2.60 A, respectively. TTHA1280 formed a homodimer in the crystals and in solution. Each subunit folds into a three-domain structure composed of a small N-terminal PUA domain, a central alpha/beta-domain and a C-terminal Rossmann-fold-like MTase domain. The three domains form an overall clamp-like shape, with the putative active site facing a deep cleft. The architecture of the active site is consistent with specific recognition of uridine and catalysis of methyl transfer to the 5-carbon position. The cleft is suitable in size and charge distribution for binding single-stranded RNA.

-	~~{{STRUCTURE_1wxw\| PDB=1wxw \| SCENE= }}~~	+	Structures of a putative RNA 5-methyluridine methyltransferase, Thermus thermophilus TTHA1280, and its complex with S-adenosyl-L-homocysteine.,Pioszak AA, Murayama K, Nakagawa N, Ebihara A, Kuramitsu S, Shirouzu M, Yokoyama S Acta Crystallogr Sect F Struct Biol Cryst Commun. 2005 Oct 1;61(Pt, 10):867-74. Epub 2005 Sep 30. PMID:16511182<ref>PMID:16511182</ref>

-	~~===Crystal structure of Tt1595~~, a ~~putative SAM-dependent methyltransferase from Thermus thermophillus HB8===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_16511182}}~~	+	== References ==
-		+	<references/>
-	~~==About this Structure==~~	+	__TOC__
-	~~[[1wxw]] is a 4 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Thermus_thermophilus Thermus thermophilus]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=1WXW OCA].~~	+	</StructureSection>
-		+
-	==~~Reference~~==	+
-	<~~ref group="xtra">PMID:016511182<~~/~~ref~~><~~references group="xtra"~~/>	+
	[[Category: Thermus thermophilus]]		[[Category: Thermus thermophilus]]
	[[Category: Ebihara, A.]]		[[Category: Ebihara, A.]]

OCA: Protected "1wxw" [edit=sysop:move=sysop]

OCA — Sat, 05 Jan 2013 13:34:55 GMT

Protected "1wxw" [edit=sysop:move=sysop]

←Older revision

Revision as of 13:34, 5 January 2013

OCA at 13:34, 5 January 2013

OCA — Sat, 05 Jan 2013 13:34:51 GMT

←Older revision		Revision as of 13:34, 5 January 2013
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-	{{Seed}}
	[[Image:1wxw.png\|left\|200px]]		[[Image:1wxw.png\|left\|200px]]

-	<!--
-	The line below this paragraph, containing "STRUCTURE_1wxw", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_1wxw\| PDB=1wxw \| SCENE= }}		{{STRUCTURE_1wxw\| PDB=1wxw \| SCENE= }}

	===Crystal structure of Tt1595, a putative SAM-dependent methyltransferase from Thermus thermophillus HB8===		===Crystal structure of Tt1595, a putative SAM-dependent methyltransferase from Thermus thermophillus HB8===

-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_16511182}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where 16511182 is the PubMed ID number.
-	-->
	{{ABSTRACT_PUBMED_16511182}}		{{ABSTRACT_PUBMED_16511182}}

	==About this Structure==		==About this Structure==
-	~~1WXW~~ is a 4 ~~chains~~ structure ~~of sequences~~ from [http://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WXW OCA].	+	[[1wxw]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WXW OCA].

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~16511182~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:016511182</ref><references group="xtra"/>
	[[Category: Thermus thermophilus]]		[[Category: Thermus thermophilus]]
	[[Category: Ebihara, A.]]		[[Category: Ebihara, A.]]
Line 41:		Line 29:
	[[Category: Structural genomic]]		[[Category: Structural genomic]]
	[[Category: Thermus thermophillus]]		[[Category: Thermus thermophillus]]
-		+	[[Category: Transferase]]
-	~~''Page seeded by~~ [~~http~~:~~//oca.weizmann.ac.il/oca OCA~~ ] ~~on Wed Feb 18 10:00:20 2009''~~	+

OCA at 08:00, 18 February 2009

OCA — Wed, 18 Feb 2009 08:00:21 GMT

←Older revision		Revision as of 08:00, 18 February 2009
Line 23:		Line 23:

	==Reference==		==Reference==
-	Structures of a putative RNA 5-methyluridine methyltransferase, Thermus thermophilus TTHA1280, and its complex with S-adenosyl-L-homocysteine., Pioszak AA, Murayama K, Nakagawa N, Ebihara A, Kuramitsu S, Shirouzu M, Yokoyama S, Acta Crystallogr Sect F Struct Biol Cryst Commun. 2005 Oct 1;61(Pt, 10):867-74. Epub 2005 Sep 30. PMID:~~[http:~~//~~www.ncbi.nlm.nih.gov/pubmed/16511182 16511182]~~	+	<ref group="xtra">PMID:16511182</ref><references group="xtra"/>
	[[Category: Thermus thermophilus]]		[[Category: Thermus thermophilus]]
	[[Category: Ebihara, A.]]		[[Category: Ebihara, A.]]
Line 42:		Line 42:
	[[Category: Thermus thermophillus]]		[[Category: Thermus thermophillus]]

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on ~~Sun Nov 16~~ 18:34:~~55 2008~~''	+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 18 10:00:20 2009''