1xkr - Revision history

OCA at 08:51, 14 February 2024

OCA — Wed, 14 Feb 2024 08:51:01 GMT

←Older revision		Revision as of 08:51, 14 February 2024
Line 3:		Line 3:
	<StructureSection load='1xkr' size='340' side='right'caption='[[1xkr]], [[Resolution\|resolution]] 1.75Å' scene=''>		<StructureSection load='1xkr' size='340' side='right'caption='[[1xkr]], [[Resolution\|resolution]] 1.75Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1xkr]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Atcc_43589 Atcc 43589~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XKR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1XKR FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1xkr]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermotoga_maritima Thermotoga maritima]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XKR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1XKR FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1xkr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1xkr OCA], [https://pdbe.org/1xkr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1xkr RCSB], [https://www.ebi.ac.uk/pdbsum/1xkr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1xkr ProSAT]</span></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.75Å</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1xkr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1xkr OCA], [https://pdbe.org/1xkr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1xkr RCSB], [https://www.ebi.ac.uk/pdbsum/1xkr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1xkr ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/CHEC_THEMA CHEC_THEMA] Involved in restoring normal CheY-P levels by dephosphorylating CheY-P. Inhibits CheD by incorporating in its fold a structural motif that mimics a CheD substrate recognition site to bait and inactivate it.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 16:		Line 19:
	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1xkr ConSurf].		</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1xkr ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
-	<div style="background-color:#fffaf0;">
-	== Publication Abstract from PubMed ==
-	In bacterial chemotaxis, phosphorylated CheY levels control the sense of flagella rotation and thereby determine swimming behavior. In E. coli, CheY dephosphorylation by CheZ extinguishes the switching signal. But, instead of CheZ, many chemotactic bacteria contain CheC, CheD, and/or CheX. The crystal structures of T. maritima CheC and CheX reveal a common fold unlike that of any other known protein. Unlike CheC, CheX dimerizes via a continuous beta sheet between subunits. T. maritima CheC, as well as CheX, dephosphorylate CheY, although CheC requires binding of CheD to achieve the activity of CheX. Structural analyses identified one conserved active site in CheX and two in CheC; mutations therein reduce CheY-phosphatase activity, but only mutants of two invariant asparagine residues are completely inactive even in the presence of CheD. Our structures indicate that the flagellar switch components FliY and FliM resemble CheC more closely than CheX, but attribute phosphatase activity only to FliY.
-
-	Structure and function of an unusual family of protein phosphatases: the bacterial chemotaxis proteins CheC and CheX.,Park SY, Chao X, Gonzalez-Bonet G, Beel BD, Bilwes AM, Crane BR Mol Cell. 2004 Nov 19;16(4):563-74. PMID:15546616<ref>PMID:15546616</ref>
-
-	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	</div>
-	<div class="pdbe-citations 1xkr" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
	*[[Chemotaxis protein 3D structures\|Chemotaxis protein 3D structures]]		*[[Chemotaxis protein 3D structures\|Chemotaxis protein 3D structures]]
-	== References ==
-	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Atcc 43589]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Beel~~, B D~~]]	+	[[Category: Thermotoga maritima]]
-	[[Category: Bilwes~~, A M~~]]	+	[[Category: Beel BD]]
-	[[Category: Chao, X]]	+	[[Category: Bilwes AM]]
-	[[Category: Crane~~, B R~~]]	+	[[Category: Chao X]]
-	[[Category: Gonzalez-Bonet, G]]	+	[[Category: Crane BR]]
-	[[Category: Park~~, S Y]]~~	+	[[Category: Gonzalez-Bonet G]]
-	~~[[Category: Attractant]]~~	+	[[Category: Park SY]]
-	~~[[Category: Chemotaxis]]~~	+
-	~~[[Category: Protein phosphatase]]~~	+
-	~~[[Category: Signal transduction~~]]	+

OCA at 16:39, 27 October 2021

OCA — Wed, 27 Oct 2021 16:39:22 GMT

←Older revision		Revision as of 16:39, 27 October 2021
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	<StructureSection load='1xkr' size='340' side='right'caption='[[1xkr]], [[Resolution\|resolution]] 1.75Å' scene=''>		<StructureSection load='1xkr' size='340' side='right'caption='[[1xkr]], [[Resolution\|resolution]] 1.75Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1xkr]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Atcc_43589 Atcc 43589]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XKR OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1XKR FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1xkr]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Atcc_43589 Atcc 43589]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XKR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1XKR FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1xkr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1xkr OCA], [~~http~~://pdbe.org/1xkr PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=1xkr RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/1xkr PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=1xkr ProSAT]</span></td></tr>	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1xkr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1xkr OCA], [https://pdbe.org/1xkr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1xkr RCSB], [https://www.ebi.ac.uk/pdbsum/1xkr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1xkr ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==

OCA at 17:22, 22 January 2020

OCA — Wed, 22 Jan 2020 17:22:08 GMT

←Older revision		Revision as of 17:22, 22 January 2020
Line 1:		Line 1:

	==X-ray Structure of Thermotoga maritima CheC==		==X-ray Structure of Thermotoga maritima CheC==
-	<StructureSection load='1xkr' size='340' side='right' caption='[[1xkr]], [[Resolution\|resolution]] 1.75Å' scene=''>	+	<StructureSection load='1xkr' size='340' side='right'caption='[[1xkr]], [[Resolution\|resolution]] 1.75Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1xkr]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_43589 Atcc 43589]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XKR OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1XKR FirstGlance]. <br>		<table><tr><td colspan='2'>[[1xkr]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_43589 Atcc 43589]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XKR OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1XKR FirstGlance]. <br>
Line 27:		Line 27:

	==See Also==		==See Also==
-	*[[Chemotaxis protein\|Chemotaxis protein]]	+	*[[Chemotaxis protein 3D structures\|Chemotaxis protein 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
Line 33:		Line 33:
	</StructureSection>		</StructureSection>
	[[Category: Atcc 43589]]		[[Category: Atcc 43589]]
		+	[[Category: Large Structures]]
	[[Category: Beel, B D]]		[[Category: Beel, B D]]
	[[Category: Bilwes, A M]]		[[Category: Bilwes, A M]]

OCA at 07:06, 18 April 2018

OCA — Wed, 18 Apr 2018 07:06:49 GMT

←Older revision		Revision as of 07:06, 18 April 2018
Line 1:		Line 1:
		+
	==X-ray Structure of Thermotoga maritima CheC==		==X-ray Structure of Thermotoga maritima CheC==
	<StructureSection load='1xkr' size='340' side='right' caption='[[1xkr]], [[Resolution\|resolution]] 1.75Å' scene=''>		<StructureSection load='1xkr' size='340' side='right' caption='[[1xkr]], [[Resolution\|resolution]] 1.75Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1xkr]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_43589 Atcc 43589]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XKR OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1XKR FirstGlance]. <br>		<table><tr><td colspan='2'>[[1xkr]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_43589 Atcc 43589]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XKR OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1XKR FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1xkr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1xkr OCA], [http://pdbe.org/1xkr PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1xkr RCSB], [http://www.ebi.ac.uk/pdbsum/1xkr PDBsum]</span></td></tr>	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1xkr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1xkr OCA], [http://pdbe.org/1xkr PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1xkr RCSB], [http://www.ebi.ac.uk/pdbsum/1xkr PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1xkr ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 9:		Line 10:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/xk/1xkr_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/xk/1xkr_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>

OCA at 06:04, 10 February 2016

OCA — Wed, 10 Feb 2016 06:04:06 GMT

←Older revision		Revision as of 06:04, 10 February 2016
Line 13:		Line 13:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1xkr ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 06:05, 11 September 2015

OCA — Fri, 11 Sep 2015 06:05:37 GMT

←Older revision		Revision as of 06:05, 11 September 2015
Line 2:		Line 2:
	<StructureSection load='1xkr' size='340' side='right' caption='[[1xkr]], [[Resolution\|resolution]] 1.75Å' scene=''>		<StructureSection load='1xkr' size='340' side='right' caption='[[1xkr]], [[Resolution\|resolution]] 1.75Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1xkr]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Thermotoga_maritima Thermotoga maritima~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XKR OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1XKR FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1xkr]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_43589 Atcc 43589]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XKR OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1XKR FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1xkr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1xkr OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1xkr RCSB], [http://www.ebi.ac.uk/pdbsum/1xkr PDBsum]</span></td></tr>	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1xkr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1xkr OCA], [http://pdbe.org/1xkr PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1xkr RCSB], [http://www.ebi.ac.uk/pdbsum/1xkr PDBsum]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
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	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 1xkr" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
Line 30:		Line 31:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Thermotoga maritima~~]]	+	[[Category: Atcc 43589]]
	[[Category: Beel, B D]]		[[Category: Beel, B D]]
	[[Category: Bilwes, A M]]		[[Category: Bilwes, A M]]

OCA at 12:30, 6 January 2015

OCA — Tue, 06 Jan 2015 12:30:45 GMT

←Older revision		Revision as of 12:30, 6 January 2015
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1xkr]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Thermotoga_maritima Thermotoga maritima]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XKR OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1XKR FirstGlance]. <br>		<table><tr><td colspan='2'>[[1xkr]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Thermotoga_maritima Thermotoga maritima]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XKR OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1XKR FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1xkr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1xkr OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1xkr RCSB], [http://www.ebi.ac.uk/pdbsum/1xkr PDBsum]</span></td></tr>	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1xkr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1xkr OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1xkr RCSB], [http://www.ebi.ac.uk/pdbsum/1xkr PDBsum]</span></td></tr>
-	<table>	+	</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 31:		Line 31:
	</StructureSection>		</StructureSection>
	[[Category: Thermotoga maritima]]		[[Category: Thermotoga maritima]]
-	[[Category: Beel, B D.]]	+	[[Category: Beel, B D]]
-	[[Category: Bilwes, A M.]]	+	[[Category: Bilwes, A M]]
-	[[Category: Chao, X.]]	+	[[Category: Chao, X]]
-	[[Category: Crane, B R.]]	+	[[Category: Crane, B R]]
-	[[Category: Gonzalez-Bonet, G.]]	+	[[Category: Gonzalez-Bonet, G]]
-	[[Category: Park, S Y.]]	+	[[Category: Park, S Y]]
	[[Category: Attractant]]		[[Category: Attractant]]
	[[Category: Chemotaxis]]		[[Category: Chemotaxis]]
	[[Category: Protein phosphatase]]		[[Category: Protein phosphatase]]
	[[Category: Signal transduction]]		[[Category: Signal transduction]]

OCA at 19:27, 29 September 2014

OCA — Mon, 29 Sep 2014 19:27:21 GMT

←Older revision		Revision as of 19:27, 29 September 2014
Line 1:		Line 1:
-	~~{{STRUCTURE_1xkr\| PDB=1xkr \| SCENE= }}~~	+	==X-ray Structure of Thermotoga maritima CheC==
-	===X-ray Structure of Thermotoga maritima CheC===	+	<StructureSection load='1xkr' size='340' side='right' caption='[[1xkr]], [[Resolution\|resolution]] 1.75Å' scene=''>
-	~~{{ABSTRACT_PUBMED_15546616}}~~	+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[1xkr]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Thermotoga_maritima Thermotoga maritima]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XKR OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1XKR FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1xkr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1xkr OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1xkr RCSB], [http://www.ebi.ac.uk/pdbsum/1xkr PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/xk/1xkr_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	In bacterial chemotaxis, phosphorylated CheY levels control the sense of flagella rotation and thereby determine swimming behavior. In E. coli, CheY dephosphorylation by CheZ extinguishes the switching signal. But, instead of CheZ, many chemotactic bacteria contain CheC, CheD, and/or CheX. The crystal structures of T. maritima CheC and CheX reveal a common fold unlike that of any other known protein. Unlike CheC, CheX dimerizes via a continuous beta sheet between subunits. T. maritima CheC, as well as CheX, dephosphorylate CheY, although CheC requires binding of CheD to achieve the activity of CheX. Structural analyses identified one conserved active site in CheX and two in CheC; mutations therein reduce CheY-phosphatase activity, but only mutants of two invariant asparagine residues are completely inactive even in the presence of CheD. Our structures indicate that the flagellar switch components FliY and FliM resemble CheC more closely than CheX, but attribute phosphatase activity only to FliY.

-	~~==About this~~ Structure==	+	Structure and function of an unusual family of protein phosphatases: the bacterial chemotaxis proteins CheC and CheX.,Park SY, Chao X, Gonzalez-Bonet G, Beel BD, Bilwes AM, Crane BR Mol Cell. 2004 Nov 19;16(4):563-74. PMID:15546616<ref>PMID:15546616</ref>
-	~~[[1xkr]] is a 1 chain structure with sequence from [http~~:~~//en~~.~~wikipedia~~.~~org/wiki/Thermotoga_maritima Thermotoga maritima]~~. ~~Full crystallographic information is available from [http~~://~~oca~~.~~weizmann~~.ac.il/~~oca-bin/ocashort?id=1XKR OCA].~~	+
		+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>

	==See Also==		==See Also==
	*[[Chemotaxis protein\|Chemotaxis protein]]		*[[Chemotaxis protein\|Chemotaxis protein]]
-		+	== References ==
-	==~~Reference~~==	+	<references/>
-	<~~ref group="xtra">PMID:015546616<~~/~~ref~~><~~references group="xtra"~~/>	+	__TOC__
		+	</StructureSection>
	[[Category: Thermotoga maritima]]		[[Category: Thermotoga maritima]]
	[[Category: Beel, B D.]]		[[Category: Beel, B D.]]

OCA at 10:19, 11 March 2013

OCA — Mon, 11 Mar 2013 10:19:56 GMT

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	{{STRUCTURE_1xkr\| PDB=1xkr \| SCENE= }}		{{STRUCTURE_1xkr\| PDB=1xkr \| SCENE= }}
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	===X-ray Structure of Thermotoga maritima CheC===		===X-ray Structure of Thermotoga maritima CheC===
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	{{ABSTRACT_PUBMED_15546616}}		{{ABSTRACT_PUBMED_15546616}}

OCA: Protected "1xkr" [edit=sysop:move=sysop]

OCA — Sat, 05 Jan 2013 12:32:57 GMT

Protected "1xkr" [edit=sysop:move=sysop]

←Older revision

Revision as of 12:32, 5 January 2013