1xy9 - Revision history

OCA at 09:30, 6 December 2023

OCA — Wed, 06 Dec 2023 09:30:16 GMT

←Older revision		Revision as of 09:30, 6 December 2023
Line 1:		Line 1:

	==NMR strcutre of sst1-selective somatostatin (SRIF) analog 1==		==NMR strcutre of sst1-selective somatostatin (SRIF) analog 1==
-	<StructureSection load='1xy9' size='340' side='right'caption='[[1xy9~~]], [[NMR_Ensembles_of_Models \| 10 NMR models~~]]' scene=''>	+	<StructureSection load='1xy9' size='340' side='right'caption='[[1xy9]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1xy9]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XY9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1XY9 FirstGlance]. <br>		<table><tr><td colspan='2'>[[1xy9]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XY9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1XY9 FirstGlance]. <br>
-	</td></tr><tr id='~~NonStdRes~~'><td class="sblockLbl"><b>[[~~Non-Standard_Residue~~\|~~NonStd Res~~:]]</b></td><td class="sblockDat"><scene name='pdbligand=DTR:D-TRYPTOPHAN'>DTR</scene>, <scene name='pdbligand=IAM:4-[(ISOPROPYLAMINO)METHYL]PHENYLALANINE'>IAM</scene>, <scene name='pdbligand=IYR:3-IODO-TYROSINE'>IYR</scene~~></td></tr>~~	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1xxz\|1xxz]], [[1xy4\|1xy4]], [[1xy5\|1xy5]], [[1xy6\|1xy6]], [[1xy8\|1xy8]]</div></td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DTR:D-TRYPTOPHAN'>DTR</scene>, <scene name='pdbligand=IAM:4-[(ISOPROPYLAMINO)METHYL]PHENYLALANINE'>IAM</scene>, <scene name='pdbligand=IYR:3-IODO-TYROSINE'>IYR</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1xy9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1xy9 OCA], [https://pdbe.org/1xy9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1xy9 RCSB], [https://www.ebi.ac.uk/pdbsum/1xy9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1xy9 ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1xy9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1xy9 OCA], [https://pdbe.org/1xy9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1xy9 RCSB], [https://www.ebi.ac.uk/pdbsum/1xy9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1xy9 ProSAT]</span></td></tr>
	</table>		</table>
Line 22:		Line 22:
	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Durrer, L]]	+	[[Category: Durrer L]]
-	[[Category: Erchegyi, J]]	+	[[Category: Erchegyi J]]
-	[[Category: Grace~~, C R.R~~]]	+	[[Category: Grace CRR]]
-	[[Category: Koerber~~, S C~~]]	+	[[Category: Koerber SC]]
-	[[Category: Reubi~~, J C~~]]	+	[[Category: Reubi JC]]
-	[[Category: Riek, R]]	+	[[Category: Riek R]]
-	[[Category: Rivier~~, J E]]~~	+	[[Category: Rivier JE]]
-	~~[[Category: Gamma turn]]~~	+
-	~~[[Category: Hormone-growth factor complex~~]]	+

OCA at 16:21, 3 November 2021

OCA — Wed, 03 Nov 2021 16:21:32 GMT

←Older revision		Revision as of 16:21, 3 November 2021
Line 3:		Line 3:
	<StructureSection load='1xy9' size='340' side='right'caption='[[1xy9]], [[NMR_Ensembles_of_Models \| 10 NMR models]]' scene=''>		<StructureSection load='1xy9' size='340' side='right'caption='[[1xy9]], [[NMR_Ensembles_of_Models \| 10 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1xy9]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XY9 OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1XY9 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1xy9]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XY9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1XY9 FirstGlance]. <br>
	</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=DTR:D-TRYPTOPHAN'>DTR</scene>, <scene name='pdbligand=IAM:4-[(ISOPROPYLAMINO)METHYL]PHENYLALANINE'>IAM</scene>, <scene name='pdbligand=IYR:3-IODO-TYROSINE'>IYR</scene></td></tr>		</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=DTR:D-TRYPTOPHAN'>DTR</scene>, <scene name='pdbligand=IAM:4-[(ISOPROPYLAMINO)METHYL]PHENYLALANINE'>IAM</scene>, <scene name='pdbligand=IYR:3-IODO-TYROSINE'>IYR</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1xxz\|1xxz]], [[1xy4\|1xy4]], [[1xy5\|1xy5]], [[1xy6\|1xy6]], [[1xy8\|1xy8]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1xxz\|1xxz]], [[1xy4\|1xy4]], [[1xy5\|1xy5]], [[1xy6\|1xy6]], [[1xy8\|1xy8]]</div></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1xy9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1xy9 OCA], [~~http~~://pdbe.org/1xy9 PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=1xy9 RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/1xy9 PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=1xy9 ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1xy9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1xy9 OCA], [https://pdbe.org/1xy9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1xy9 RCSB], [https://www.ebi.ac.uk/pdbsum/1xy9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1xy9 ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 16:47, 29 January 2020

OCA — Wed, 29 Jan 2020 16:47:24 GMT

←Older revision		Revision as of 16:47, 29 January 2020
Line 1:		Line 1:

	==NMR strcutre of sst1-selective somatostatin (SRIF) analog 1==		==NMR strcutre of sst1-selective somatostatin (SRIF) analog 1==
-	<StructureSection load='1xy9' size='340' side='right' caption='[[1xy9]], [[NMR_Ensembles_of_Models \| 10 NMR models]]' scene=''>	+	<StructureSection load='1xy9' size='340' side='right'caption='[[1xy9]], [[NMR_Ensembles_of_Models \| 10 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1xy9]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XY9 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1XY9 FirstGlance]. <br>		<table><tr><td colspan='2'>[[1xy9]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XY9 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1XY9 FirstGlance]. <br>
Line 21:		Line 21:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Large Structures]]
	[[Category: Durrer, L]]		[[Category: Durrer, L]]
	[[Category: Erchegyi, J]]		[[Category: Erchegyi, J]]

OCA at 07:07, 18 April 2018

OCA — Wed, 18 Apr 2018 07:07:13 GMT

←Older revision		Revision as of 07:07, 18 April 2018
Line 1:		Line 1:
		+
	==NMR strcutre of sst1-selective somatostatin (SRIF) analog 1==		==NMR strcutre of sst1-selective somatostatin (SRIF) analog 1==
	<StructureSection load='1xy9' size='340' side='right' caption='[[1xy9]], [[NMR_Ensembles_of_Models \| 10 NMR models]]' scene=''>		<StructureSection load='1xy9' size='340' side='right' caption='[[1xy9]], [[NMR_Ensembles_of_Models \| 10 NMR models]]' scene=''>
Line 5:		Line 6:
	</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=DTR:D-TRYPTOPHAN'>DTR</scene>, <scene name='pdbligand=IAM:4-[(ISOPROPYLAMINO)METHYL]PHENYLALANINE'>IAM</scene>, <scene name='pdbligand=IYR:3-IODO-TYROSINE'>IYR</scene></td></tr>		</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=DTR:D-TRYPTOPHAN'>DTR</scene>, <scene name='pdbligand=IAM:4-[(ISOPROPYLAMINO)METHYL]PHENYLALANINE'>IAM</scene>, <scene name='pdbligand=IYR:3-IODO-TYROSINE'>IYR</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1xxz\|1xxz]], [[1xy4\|1xy4]], [[1xy5\|1xy5]], [[1xy6\|1xy6]], [[1xy8\|1xy8]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1xxz\|1xxz]], [[1xy4\|1xy4]], [[1xy5\|1xy5]], [[1xy6\|1xy6]], [[1xy8\|1xy8]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1xy9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1xy9 OCA], [http://pdbe.org/1xy9 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1xy9 RCSB], [http://www.ebi.ac.uk/pdbsum/1xy9 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1xy9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1xy9 OCA], [http://pdbe.org/1xy9 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1xy9 RCSB], [http://www.ebi.ac.uk/pdbsum/1xy9 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1xy9 ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 04:00, 10 September 2015

OCA — Thu, 10 Sep 2015 04:00:23 GMT

←Older revision		Revision as of 04:00, 10 September 2015
Line 5:		Line 5:
	</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=DTR:D-TRYPTOPHAN'>DTR</scene>, <scene name='pdbligand=IAM:4-[(ISOPROPYLAMINO)METHYL]PHENYLALANINE'>IAM</scene>, <scene name='pdbligand=IYR:3-IODO-TYROSINE'>IYR</scene></td></tr>		</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=DTR:D-TRYPTOPHAN'>DTR</scene>, <scene name='pdbligand=IAM:4-[(ISOPROPYLAMINO)METHYL]PHENYLALANINE'>IAM</scene>, <scene name='pdbligand=IYR:3-IODO-TYROSINE'>IYR</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1xxz\|1xxz]], [[1xy4\|1xy4]], [[1xy5\|1xy5]], [[1xy6\|1xy6]], [[1xy8\|1xy8]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1xxz\|1xxz]], [[1xy4\|1xy4]], [[1xy5\|1xy5]], [[1xy6\|1xy6]], [[1xy8\|1xy8]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1xy9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1xy9 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1xy9 RCSB], [http://www.ebi.ac.uk/pdbsum/1xy9 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1xy9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1xy9 OCA], [http://pdbe.org/1xy9 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1xy9 RCSB], [http://www.ebi.ac.uk/pdbsum/1xy9 PDBsum]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 15:		Line 15:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 1xy9" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>

OCA at 05:08, 22 December 2014

OCA — Mon, 22 Dec 2014 05:08:31 GMT

←Older revision		Revision as of 05:08, 22 December 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1xy9]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XY9 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1XY9 FirstGlance]. <br>		<table><tr><td colspan='2'>[[1xy9]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XY9 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1XY9 FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=DTR:D-TRYPTOPHAN'>DTR</scene>, <scene name='pdbligand=IAM:4-[(ISOPROPYLAMINO)METHYL]PHENYLALANINE'>IAM</scene>, <scene name='pdbligand=IYR:3-IODO-TYROSINE'>IYR</scene></td></tr>	+	</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=DTR:D-TRYPTOPHAN'>DTR</scene>, <scene name='pdbligand=IAM:4-[(ISOPROPYLAMINO)METHYL]PHENYLALANINE'>IAM</scene>, <scene name='pdbligand=IYR:3-IODO-TYROSINE'>IYR</scene></td></tr>
-	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1xxz\|1xxz]], [[1xy4\|1xy4]], [[1xy5\|1xy5]], [[1xy6\|1xy6]], [[1xy8\|1xy8]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1xxz\|1xxz]], [[1xy4\|1xy4]], [[1xy5\|1xy5]], [[1xy6\|1xy6]], [[1xy8\|1xy8]]</td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1xy9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1xy9 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1xy9 RCSB], [http://www.ebi.ac.uk/pdbsum/1xy9 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1xy9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1xy9 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1xy9 RCSB], [http://www.ebi.ac.uk/pdbsum/1xy9 PDBsum]</span></td></tr>
-	<table>	+	</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 19:		Line 19:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Durrer, L.]]	+	[[Category: Durrer, L]]
-	[[Category: Erchegyi, J.]]	+	[[Category: Erchegyi, J]]
-	[[Category: Grace, C R.R.]]	+	[[Category: Grace, C R.R]]
-	[[Category: Koerber, S C.]]	+	[[Category: Koerber, S C]]
-	[[Category: Reubi, J C.]]	+	[[Category: Reubi, J C]]
-	[[Category: Riek, R.]]	+	[[Category: Riek, R]]
-	[[Category: Rivier, J E.]]	+	[[Category: Rivier, J E]]
	[[Category: Gamma turn]]		[[Category: Gamma turn]]
	[[Category: Hormone-growth factor complex]]		[[Category: Hormone-growth factor complex]]

OCA at 06:53, 9 June 2014

OCA — Mon, 09 Jun 2014 06:53:06 GMT

←Older revision		Revision as of 06:53, 9 June 2014
Line 1:		Line 1:
-	[[~~Image:~~1xy9.~~png~~\|~~left~~\|~~200px~~]]	+	==NMR strcutre of sst1-selective somatostatin (SRIF) analog 1==
		+	<StructureSection load='1xy9' size='340' side='right' caption='[[1xy9]], [[NMR_Ensembles_of_Models \| 10 NMR models]]' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[1xy9]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XY9 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1XY9 FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=DTR:D-TRYPTOPHAN'>DTR</scene>, <scene name='pdbligand=IAM:4-[(ISOPROPYLAMINO)METHYL]PHENYLALANINE'>IAM</scene>, <scene name='pdbligand=IYR:3-IODO-TYROSINE'>IYR</scene></td></tr>
		+	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1xxz\|1xxz]], [[1xy4\|1xy4]], [[1xy5\|1xy5]], [[1xy6\|1xy6]], [[1xy8\|1xy8]]</td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1xy9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1xy9 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1xy9 RCSB], [http://www.ebi.ac.uk/pdbsum/1xy9 PDBsum]</span></td></tr>
		+	<table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	The three-dimensional NMR structures of six analogues of somatostatin (SRIF) are described. These analogues with the amino acid 4-(N-isopropyl)-aminomethylphenylalanine (IAmp) at position 9 exhibit potent and highly selective binding to human SRIF subtype 1 receptors (sst(1)). The conformations reveal that the backbones of these analogues have a hairpin-like structure similar to the sst(2)-subtype-selective analogues. This structure serves as a scaffold for retaining a unique arrangement of the side chains of d-Trp(8), IAmp(9), Phe(7), and Phe(11) or m-I-Tyr(11) (m-I-Tyr = mono-iodo-tyrosine). The conformational preferences and results from biological analyses of these analogues(1,2) allow a detailed study of the structure-activity relationship of SRIF. The proposed consensus pharmacophore of the sst(1)-selective analogues requires a unique set of distances between an indole/2-naphthyl ring, an IAmp side chain, and two aromatic rings. This motif is necessary and sufficient to explain the binding affinities of all of the analogues studied and is distinct from the existing models suggested for sst(4) as well as sst(2)/sst(5) selectivity.

-	~~{{STRUCTURE_1xy9\| PDB=1xy9 \| SCENE= }}~~	+	Somatostatin receptor 1 selective analogues: 4. Three-dimensional consensus structure by NMR.,Grace CR, Durrer L, Koerber SC, Erchegyi J, Reubi JC, Rivier JE, Riek R J Med Chem. 2005 Jan 27;48(2):523-33. PMID:15658866<ref>PMID:15658866</ref>

-	~~===NMR strcutre~~ of ~~sst1-selective somatostatin (SRIF) analog 1===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_15658866}}~~	+	== References ==
-		+	<references/>
-	~~==About this Structure==~~	+	__TOC__
-	~~[[1xy9]] is a 1 chain structure~~. ~~Full experimental information is available from [http://oca~~.~~weizmann~~.~~ac.il~~/~~oca-bin/ocashort?id=1XY9 OCA].~~	+	</StructureSection>
-		+
-	==~~Reference~~==	+
-	<~~ref group="xtra">PMID:015658866<~~/~~ref~~><~~references group="xtra"~~/>	+
	[[Category: Durrer, L.]]		[[Category: Durrer, L.]]
	[[Category: Erchegyi, J.]]		[[Category: Erchegyi, J.]]

OCA: Protected "1xy9" [edit=sysop:move=sysop]

OCA — Tue, 14 Aug 2012 15:09:50 GMT

Protected "1xy9" [edit=sysop:move=sysop]

←Older revision

Revision as of 15:09, 14 August 2012

OCA at 15:09, 14 August 2012

OCA — Tue, 14 Aug 2012 15:09:48 GMT

←Older revision		Revision as of 15:09, 14 August 2012
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-	{{Seed}}
	[[Image:1xy9.png\|left\|200px]]		[[Image:1xy9.png\|left\|200px]]

-	<!--
-	The line below this paragraph, containing "STRUCTURE_1xy9", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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	{{STRUCTURE_1xy9\| PDB=1xy9 \| SCENE= }}		{{STRUCTURE_1xy9\| PDB=1xy9 \| SCENE= }}

	===NMR strcutre of sst1-selective somatostatin (SRIF) analog 1===		===NMR strcutre of sst1-selective somatostatin (SRIF) analog 1===

-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_15658866}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where 15658866 is the PubMed ID number.
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	{{ABSTRACT_PUBMED_15658866}}		{{ABSTRACT_PUBMED_15658866}}

	==About this Structure==		==About this Structure==
-	Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XY9 OCA].	+	[[1xy9]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XY9 OCA].

	==Reference==		==Reference==
-	Somatostatin receptor 1 selective analogues: 4. Three-dimensional consensus structure by NMR., Grace CR, Durrer L, Koerber SC, Erchegyi J, Reubi JC, Rivier JE, Riek R, J Med Chem. 2005 Jan 27;48(2):523-33. PMID:~~[http://www.ncbi.nlm.nih.gov~~/~~pubmed~~/~~15658866 15658866]~~	+	<ref group="xtra">PMID:015658866</ref><references group="xtra"/>
	[[Category: Durrer, L.]]		[[Category: Durrer, L.]]
	[[Category: Erchegyi, J.]]		[[Category: Erchegyi, J.]]
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	[[Category: Rivier, J E.]]		[[Category: Rivier, J E.]]
	[[Category: Gamma turn]]		[[Category: Gamma turn]]
-		+	[[Category: Hormone-growth factor complex]]
-	~~''Page seeded by~~ [~~http~~:~~//oca.weizmann.ac.il/oca OCA~~ ] ~~on Sun Jul 27 18:41:49 2008''~~	+

OCA at 15:41, 27 July 2008

OCA — Sun, 27 Jul 2008 15:41:56 GMT

←Older revision		Revision as of 15:41, 27 July 2008
Line 1:		Line 1:
-	[[Image:1xy9.~~gif~~\|left\|200px]]	+	{{Seed}}
		+	[[Image:1xy9.png\|left\|200px]]

	<!--		<!--
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	{{STRUCTURE_1xy9\| PDB=1xy9 \| SCENE= }}		{{STRUCTURE_1xy9\| PDB=1xy9 \| SCENE= }}

-	~~'''~~NMR strcutre of sst1-selective somatostatin (SRIF) analog 1~~'''~~	+	===NMR strcutre of sst1-selective somatostatin (SRIF) analog 1===


-	~~==Overview==~~	+	<!--
-	~~The three~~-~~dimensional NMR structures of six analogues of somatostatin (SRIF) are described. These analogues with the amino acid 4~~-~~(N-isopropyl)-aminomethylphenylalanine (IAmp) at position 9 exhibit potent and highly selective binding to human SRIF subtype 1 receptors (sst(1)).~~ The ~~conformations reveal that~~ the ~~backbones of these analogues have a hairpin-like structure similar~~ to the ~~sst~~(~~2)-subtype-selective analogues. This structure serves~~ as ~~a scaffold for retaining a unique arrangement of the side chains of d-Trp(8), IAmp(9), Phe(7), and Phe(11) or m-I-Tyr(11) (m-I-Tyr = mono-iodo-tyrosine)~~. ~~The conformational preferences and results from biological analyses of these analogues(1,2) allow a detailed study of the structure-activity relationship of SRIF~~. ~~The proposed consensus pharmacophore of the sst(1~~)~~-selective analogues requires a unique set of distances between an indole/2-naphthyl ring~~, ~~an IAmp side chain, and two aromatic rings. This motif~~ is ~~necessary and sufficient to explain~~ the ~~binding affinities of all of the analogues studied and is distinct from the existing models suggested for sst(4) as well as sst(2)/sst(5) selectivity~~.	+	The line below this paragraph, {{ABSTRACT_PUBMED_15658866}}, adds the Publication Abstract to the page
		+	(as it appears on PubMed at http://www.pubmed.gov), where 15658866 is the PubMed ID number.
		+	-->
		+	{{ABSTRACT_PUBMED_15658866}}

	==About this Structure==		==About this Structure==
-	Full ~~crystallographic~~ information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XY9 OCA].	+	Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XY9 OCA].

	==Reference==		==Reference==
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	[[Category: Rivier, J E.]]		[[Category: Rivier, J E.]]
	[[Category: Gamma turn]]		[[Category: Gamma turn]]
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on ~~Sat May 3 15~~:39:32 2008''	+
		+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Jul 27 18:41:49 2008''