1xzh - Revision history

OCA at 07:59, 15 May 2024

OCA — Wed, 15 May 2024 07:59:17 GMT

←Older revision		Revision as of 07:59, 15 May 2024
Line 3:		Line 3:
	<StructureSection load='1xzh' size='340' side='right'caption='[[1xzh]], [[Resolution\|resolution]] 1.69Å' scene=''>		<StructureSection load='1xzh' size='340' side='right'caption='[[1xzh]], [[Resolution\|resolution]] 1.69Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1xzh]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XZH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1XZH FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1xzh]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Fusarium_vanettenii Fusarium vanettenii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XZH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1XZH FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1xzh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1xzh OCA], [https://pdbe.org/1xzh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1xzh RCSB], [https://www.ebi.ac.uk/pdbsum/1xzh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1xzh ProSAT]</span></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.69Å</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1xzh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1xzh OCA], [https://pdbe.org/1xzh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1xzh RCSB], [https://www.ebi.ac.uk/pdbsum/1xzh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1xzh ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[https://www.uniprot.org/uniprot/~~CUTI1_FUSSO CUTI1_FUSSO]~~] Catalyzes the hydrolysis of cutin, a ~~polyester~~ that forms the structure of plant cuticle. Allows pathogenic fungi to penetrate through the cuticular barrier into the host plant during the initial stage of ~~the~~ fungal infection.	+	[https://www.uniprot.org/uniprot/CUTI1_FUSVN CUTI1_FUSVN] Catalyzes the hydrolysis of complex carboxylic polyesters found in the cell wall of plants (PubMed:18658138, PubMed:8286366, PubMed:8555209, PubMed:19810726). Degrades cutin, a macromolecule that forms the structure of the plant cuticle (PubMed:18658138, PubMed:8286366, PubMed:8555209, PubMed:19810726). Allows pathogenic fungi to penetrate through the cuticular barrier into the host plant during the initial stage of fungal infection (Ref.4).<ref>PMID:18658138</ref> <ref>PMID:19810726</ref> <ref>PMID:8286366</ref> <ref>PMID:8555209</ref> [PROSITE-ProRule:PRU10109]
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 34:		Line 35:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Fusarium vanettenii]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Cambillau, C]]	+	[[Category: Cambillau C]]
-	[[Category: Nicolas, A]]	+	[[Category: Nicolas A]]
-	~~[[Category: Glycoprotein]]~~	+
-	~~[[Category: Hydrolase]]~~	+
-	~~[[Category: Serine esterase~~]]	+

OCA at 15:35, 3 November 2021

OCA — Wed, 03 Nov 2021 15:35:06 GMT

←Older revision		Revision as of 15:35, 3 November 2021
Line 3:		Line 3:
	<StructureSection load='1xzh' size='340' side='right'caption='[[1xzh]], [[Resolution\|resolution]] 1.69Å' scene=''>		<StructureSection load='1xzh' size='340' side='right'caption='[[1xzh]], [[Resolution\|resolution]] 1.69Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1xzh]] is a 1 chain structure ~~with sequence from [http://en.wikipedia.org/wiki/Fusso Fusso]~~. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XZH OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1XZH FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1xzh]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XZH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1XZH FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1xzh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1xzh OCA], [~~http~~://pdbe.org/1xzh PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=1xzh RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/1xzh PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=1xzh ProSAT]</span></td></tr>	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1xzh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1xzh OCA], [https://pdbe.org/1xzh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1xzh RCSB], [https://www.ebi.ac.uk/pdbsum/1xzh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1xzh ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[~~http~~://www.uniprot.org/uniprot/CUTI1_FUSSO CUTI1_FUSSO]] Catalyzes the hydrolysis of cutin, a polyester that forms the structure of plant cuticle. Allows pathogenic fungi to penetrate through the cuticular barrier into the host plant during the initial stage of the fungal infection.	+	[[https://www.uniprot.org/uniprot/CUTI1_FUSSO CUTI1_FUSSO]] Catalyzes the hydrolysis of cutin, a polyester that forms the structure of plant cuticle. Allows pathogenic fungi to penetrate through the cuticular barrier into the host plant during the initial stage of the fungal infection.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 34:		Line 34:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Fusso]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
	[[Category: Cambillau, C]]		[[Category: Cambillau, C]]

OCA at 16:33, 29 January 2020

OCA — Wed, 29 Jan 2020 16:33:24 GMT

←Older revision		Revision as of 16:33, 29 January 2020
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	==FUSARIUM SOLANI CUTINASE MUTANT WITH THR 80 REPLACED BY PRO==		==FUSARIUM SOLANI CUTINASE MUTANT WITH THR 80 REPLACED BY PRO==
-	<StructureSection load='1xzh' size='340' side='right' caption='[[1xzh]], [[Resolution\|resolution]] 1.69Å' scene=''>	+	<StructureSection load='1xzh' size='340' side='right'caption='[[1xzh]], [[Resolution\|resolution]] 1.69Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1xzh]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Fusso Fusso]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XZH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1XZH FirstGlance]. <br>		<table><tr><td colspan='2'>[[1xzh]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Fusso Fusso]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XZH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1XZH FirstGlance]. <br>
Line 29:		Line 29:

	==See Also==		==See Also==
-	*[[Cutinase\|Cutinase]]	+	*[[Cutinase 3D structures\|Cutinase 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
Line 35:		Line 35:
	</StructureSection>		</StructureSection>
	[[Category: Fusso]]		[[Category: Fusso]]
		+	[[Category: Large Structures]]
	[[Category: Cambillau, C]]		[[Category: Cambillau, C]]
	[[Category: Nicolas, A]]		[[Category: Nicolas, A]]

OCA at 06:54, 18 April 2018

OCA — Wed, 18 Apr 2018 06:54:14 GMT

←Older revision		Revision as of 06:54, 18 April 2018
Line 1:		Line 1:
		+
	==FUSARIUM SOLANI CUTINASE MUTANT WITH THR 80 REPLACED BY PRO==		==FUSARIUM SOLANI CUTINASE MUTANT WITH THR 80 REPLACED BY PRO==
	<StructureSection load='1xzh' size='340' side='right' caption='[[1xzh]], [[Resolution\|resolution]] 1.69Å' scene=''>		<StructureSection load='1xzh' size='340' side='right' caption='[[1xzh]], [[Resolution\|resolution]] 1.69Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1xzh]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Fusso Fusso]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XZH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1XZH FirstGlance]. <br>		<table><tr><td colspan='2'>[[1xzh]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Fusso Fusso]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XZH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1XZH FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1xzh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1xzh OCA], [http://pdbe.org/1xzh PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1xzh RCSB], [http://www.ebi.ac.uk/pdbsum/1xzh PDBsum]</span></td></tr>	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1xzh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1xzh OCA], [http://pdbe.org/1xzh PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1xzh RCSB], [http://www.ebi.ac.uk/pdbsum/1xzh PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1xzh ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 11:		Line 12:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/xz/1xzh_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/xz/1xzh_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>

OCA at 08:49, 9 February 2016

OCA — Tue, 09 Feb 2016 08:49:11 GMT

←Older revision		Revision as of 08:49, 9 February 2016
Line 15:		Line 15:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1xzh ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 20:36, 10 September 2015

OCA — Thu, 10 Sep 2015 20:36:01 GMT

←Older revision		Revision as of 20:36, 10 September 2015
Line 2:		Line 2:
	<StructureSection load='1xzh' size='340' side='right' caption='[[1xzh]], [[Resolution\|resolution]] 1.69Å' scene=''>		<StructureSection load='1xzh' size='340' side='right' caption='[[1xzh]], [[Resolution\|resolution]] 1.69Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1xzh]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Nectria_haematococca_mpvi Nectria haematococca mpvi~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XZH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1XZH FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1xzh]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Fusso Fusso]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XZH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1XZH FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1xzh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1xzh OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1xzh RCSB], [http://www.ebi.ac.uk/pdbsum/1xzh PDBsum]</span></td></tr>	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1xzh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1xzh OCA], [http://pdbe.org/1xzh PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1xzh RCSB], [http://www.ebi.ac.uk/pdbsum/1xzh PDBsum]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 25:		Line 25:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 1xzh" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
Line 32:		Line 33:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Nectria haematococca mpvi~~]]	+	[[Category: Fusso]]
	[[Category: Cambillau, C]]		[[Category: Cambillau, C]]
	[[Category: Nicolas, A]]		[[Category: Nicolas, A]]

OCA at 05:49, 25 December 2014

OCA — Thu, 25 Dec 2014 05:49:37 GMT

←Older revision		Revision as of 05:49, 25 December 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1xzh]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Nectria_haematococca_mpvi Nectria haematococca mpvi]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XZH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1XZH FirstGlance]. <br>		<table><tr><td colspan='2'>[[1xzh]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Nectria_haematococca_mpvi Nectria haematococca mpvi]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XZH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1XZH FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1xzh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1xzh OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1xzh RCSB], [http://www.ebi.ac.uk/pdbsum/1xzh PDBsum]</span></td></tr>	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1xzh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1xzh OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1xzh RCSB], [http://www.ebi.ac.uk/pdbsum/1xzh PDBsum]</span></td></tr>
-	<table>	+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/CUTI1_FUSSO CUTI1_FUSSO]] Catalyzes the hydrolysis of cutin, a polyester that forms the structure of plant cuticle. Allows pathogenic fungi to penetrate through the cuticular barrier into the host plant during the initial stage of the fungal infection.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 31:		Line 33:
	</StructureSection>		</StructureSection>
	[[Category: Nectria haematococca mpvi]]		[[Category: Nectria haematococca mpvi]]
-	[[Category: Cambillau, C.]]	+	[[Category: Cambillau, C]]
-	[[Category: Nicolas, A.]]	+	[[Category: Nicolas, A]]
	[[Category: Glycoprotein]]		[[Category: Glycoprotein]]
	[[Category: Hydrolase]]		[[Category: Hydrolase]]
	[[Category: Serine esterase]]		[[Category: Serine esterase]]

OCA at 21:14, 29 September 2014

OCA — Mon, 29 Sep 2014 21:14:37 GMT

←Older revision		Revision as of 21:14, 29 September 2014
Line 1:		Line 1:
-	[[~~Image~~:1xzh.~~png\|left~~\|200px]]	+	==FUSARIUM SOLANI CUTINASE MUTANT WITH THR 80 REPLACED BY PRO==
		+	<StructureSection load='1xzh' size='340' side='right' caption='[[1xzh]], [[Resolution\|resolution]] 1.69Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[1xzh]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Nectria_haematococca_mpvi Nectria haematococca mpvi]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XZH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1XZH FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1xzh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1xzh OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1xzh RCSB], [http://www.ebi.ac.uk/pdbsum/1xzh PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/xz/1xzh_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	In characterizing mutants and covalently inhibited complexes of Fusarium solani cutinase, which is a 197-residue lipolytic enzyme, 34 variant structures, crystallizing in 8 different crystal forms, have been determined, mostly at high resolution. Taking advantage of this considerable body of information, a structural comparative analysis was carried out to investigate the dynamics of cutinase. Surface loops were identified as the major flexible protein regions, particularly those forming the active-site groove, whereas the elements constituting the protein scaffold were found to retain the same conformation in all the cutinase variants studied. Flexibility turned out to be correlated with thermal motion. With a given crystal packing environment, a high flexibility turned out to be correlated with a low involvement in crystal packing contacts. The high degree of crystal polymorphism, which allowed different conformations with similar energy to be detected, made it possible to identify motions which would have remained unidentified if only a single crystal form had been available. Fairly good agreement was found to exist between the data obtained from the structural comparison and those from a molecular dynamics (MD) simulation carried out on the native enzyme. The crystallographic approach used in this study turned out to be a suitable tool for investigating cutinase dynamics. Because of the availability of a set of closely related proteins in different crystal environments, the intrinsic drawback of a crystallographic approach was bypassed. By combining several static pictures, the dynamics of the protein could be monitored much more realistically than what can be achieved on the basis of static pictures alone.

-	~~{{STRUCTURE_1xzh\| PDB=1xzh \| SCENE= }}~~	+	Dynamics of Fusarium solani cutinase investigated through structural comparison among different crystal forms of its variants.,Longhi S, Nicolas A, Creveld L, Egmond M, Verrips CT, de Vlieg J, Martinez C, Cambillau C Proteins. 1996 Dec;26(4):442-58. PMID:8990497<ref>PMID:8990497</ref>

-	~~===FUSARIUM SOLANI CUTINASE MUTANT WITH THR 80 REPLACED BY PRO===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>

-	~~{{ABSTRACT_PUBMED_8990497}}~~	+	==See Also==
-		+	*[[Cutinase\|Cutinase]]
-	==~~About this Structure~~==	+	== References ==
-	[[~~1xzh~~]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Nectria_haematococca_mpvi Nectria haematococca mpvi]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XZH OCA].	+	<references/>
-		+	__TOC__
-	==~~Reference~~==	+	</StructureSection>
-	<~~ref group="xtra">PMID:008990497<~~/~~ref~~><~~references group="xtra"~~/>	+
	[[Category: Nectria haematococca mpvi]]		[[Category: Nectria haematococca mpvi]]
	[[Category: Cambillau, C.]]		[[Category: Cambillau, C.]]

OCA: Protected "1xzh" [edit=sysop:move=sysop]

OCA — Sat, 05 Jan 2013 12:20:06 GMT

Protected "1xzh" [edit=sysop:move=sysop]

←Older revision

Revision as of 12:20, 5 January 2013

OCA at 12:20, 5 January 2013

OCA — Sat, 05 Jan 2013 12:20:03 GMT

←Older revision		Revision as of 12:20, 5 January 2013
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-	{{Seed}}
	[[Image:1xzh.png\|left\|200px]]		[[Image:1xzh.png\|left\|200px]]

-	<!--
-	The line below this paragraph, containing "STRUCTURE_1xzh", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_1xzh\| PDB=1xzh \| SCENE= }}		{{STRUCTURE_1xzh\| PDB=1xzh \| SCENE= }}

	===FUSARIUM SOLANI CUTINASE MUTANT WITH THR 80 REPLACED BY PRO===		===FUSARIUM SOLANI CUTINASE MUTANT WITH THR 80 REPLACED BY PRO===

-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_8990497}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where 8990497 is the PubMed ID number.
-	-->
	{{ABSTRACT_PUBMED_8990497}}		{{ABSTRACT_PUBMED_8990497}}

	==About this Structure==		==About this Structure==
-	~~1XZH~~ is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/~~Fusarium_solani_subsp._pisi Fusarium solani subsp. pisi~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XZH OCA].	+	[[1xzh]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Nectria_haematococca_mpvi Nectria haematococca mpvi]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XZH OCA].

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~8990497~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:008990497</ref><references group="xtra"/>
-	[[Category: ~~Fusarium solani subsp. pisi~~]]	+	[[Category: Nectria haematococca mpvi]]
	[[Category: Cambillau, C.]]		[[Category: Cambillau, C.]]
	[[Category: Nicolas, A.]]		[[Category: Nicolas, A.]]
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	[[Category: Hydrolase]]		[[Category: Hydrolase]]
	[[Category: Serine esterase]]		[[Category: Serine esterase]]
-
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 08:29:35 2009''