1xzw - Revision history

OCA at 08:09, 25 October 2023

OCA — Wed, 25 Oct 2023 08:09:48 GMT

←Older revision		Revision as of 08:09, 25 October 2023
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	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1xzw]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Ipomoea_batatas Ipomoea batatas]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XZW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1XZW FirstGlance]. <br>		<table><tr><td colspan='2'>[[1xzw]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Ipomoea_batatas Ipomoea batatas]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XZW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1XZW FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=MN:~~MANGANESE+(II)+ION~~'>MN</scene>, <scene name='pdbligand=~~NAG~~:~~N-ACETYL~~-D-~~GLUCOSAMINE~~'>~~NAG~~</scene>, <scene name='pdbligand=~~PO4~~:~~PHOSPHATE~~+ION'>~~PO4~~</scene>, <scene name='pdbligand=~~FUC~~:~~ALPHA~~-L-~~FUCOSE~~'>~~FUC~~</scene>, <scene name='pdbligand=~~MAN~~:~~ALPHA-D-MANNOSE~~'>~~MAN~~</scene~~></td></tr>~~	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.5Å</td></tr>
-	~~<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1ute\|1ute]], [[4kbp\|4kbp]]</div></td></tr>~~	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=FUC:ALPHA-L-FUCOSE'>FUC</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Acid_phosphatase Acid phosphatase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.3.2 3.1.3.2] </span></td></tr>	+
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1xzw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1xzw OCA], [https://pdbe.org/1xzw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1xzw RCSB], [https://www.ebi.ac.uk/pdbsum/1xzw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1xzw ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1xzw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1xzw OCA], [https://pdbe.org/1xzw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1xzw RCSB], [https://www.ebi.ac.uk/pdbsum/1xzw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1xzw ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/PPAF1_IPOBA PPAF1_IPOBA]
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Acid phosphatase]]
	[[Category: Ipomoea batatas]]		[[Category: Ipomoea batatas]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Carrington~~, L E~~]]	+	[[Category: Carrington LE]]
-	[[Category: Gahan~~, L R~~]]	+	[[Category: Gahan LR]]
-	[[Category: Guddat~~, L W~~]]	+	[[Category: Guddat LW]]
-	[[Category: Hamilton~~, S E]]~~	+	[[Category: Hamilton SE]]
-	~~[[Category: Jersey, J de~~]]	+	[[Category: Schenk G]]
-	[[Category: Schenk, G]]	+	[[Category: De Jersey J]]
-	[[Category: ~~Hydrolase~~]]	+

OCA at 09:06, 21 April 2021

OCA — Wed, 21 Apr 2021 09:06:40 GMT

←Older revision		Revision as of 09:06, 21 April 2021
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	<StructureSection load='1xzw' size='340' side='right'caption='[[1xzw]], [[Resolution\|resolution]] 2.50Å' scene=''>		<StructureSection load='1xzw' size='340' side='right'caption='[[1xzw]], [[Resolution\|resolution]] 2.50Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1xzw]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Convolvulus_batatas Convolvulus~~ batatas]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XZW OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1XZW FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1xzw]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Ipomoea_batatas Ipomoea batatas]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XZW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1XZW FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=~~FUC~~:~~ALPHA-L-FUCOSE~~'>~~FUC~~</scene>, <scene name='pdbligand=~~MAN~~:~~ALPHA~~-D-~~MANNOSE~~'>~~MAN~~</scene>, <scene name='pdbligand=MN:~~MANGANESE+(II)~~+ION'>MN</scene>, <scene name='pdbligand=~~NAG~~:N-~~ACETYL-D~~-~~GLUCOSAMINE~~'>~~NAG~~</scene>, <scene name='pdbligand=~~PO4~~:~~PHOSPHATE+ION~~'>~~PO4~~</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=FUC:ALPHA-L-FUCOSE'>FUC</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1ute\|1ute]], [[4kbp\|4kbp]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1ute\|1ute]], [[4kbp\|4kbp]]</div></td></tr>
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://en.wikipedia.org/wiki/Acid_phosphatase Acid phosphatase], with EC number [~~http~~://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.3.2 3.1.3.2] </span></td></tr>	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Acid_phosphatase Acid phosphatase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.3.2 3.1.3.2] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1xzw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1xzw OCA], [~~http~~://pdbe.org/1xzw PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=1xzw RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/1xzw PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=1xzw ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1xzw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1xzw OCA], [https://pdbe.org/1xzw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1xzw RCSB], [https://www.ebi.ac.uk/pdbsum/1xzw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1xzw ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
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	</StructureSection>		</StructureSection>
	[[Category: Acid phosphatase]]		[[Category: Acid phosphatase]]
-	[[Category: ~~Convolvulus~~ batatas]]	+	[[Category: Ipomoea batatas]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
	[[Category: Carrington, L E]]		[[Category: Carrington, L E]]

OCA at 12:57, 17 July 2019

OCA — Wed, 17 Jul 2019 12:57:41 GMT

←Older revision		Revision as of 12:57, 17 July 2019
Line 1:		Line 1:

	==Sweet potato purple acid phosphatase/phosphate complex==		==Sweet potato purple acid phosphatase/phosphate complex==
-	<StructureSection load='1xzw' size='340' side='right' caption='[[1xzw]], [[Resolution\|resolution]] 2.50Å' scene=''>	+	<StructureSection load='1xzw' size='340' side='right'caption='[[1xzw]], [[Resolution\|resolution]] 2.50Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1xzw]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Convolvulus_batatas Convolvulus batatas]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XZW OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1XZW FirstGlance]. <br>		<table><tr><td colspan='2'>[[1xzw]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Convolvulus_batatas Convolvulus batatas]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XZW OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1XZW FirstGlance]. <br>
Line 13:		Line 13:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/xz/1xzw_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/xz/1xzw_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
Line 28:		Line 28:
	</div>		</div>
	<div class="pdbe-citations 1xzw" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 1xzw" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[Acid phosphatase 3D structures\|Acid phosphatase 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
Line 34:		Line 37:
	[[Category: Acid phosphatase]]		[[Category: Acid phosphatase]]
	[[Category: Convolvulus batatas]]		[[Category: Convolvulus batatas]]
		+	[[Category: Large Structures]]
	[[Category: Carrington, L E]]		[[Category: Carrington, L E]]
	[[Category: Gahan, L R]]		[[Category: Gahan, L R]]

OCA at 12:23, 12 October 2017

OCA — Thu, 12 Oct 2017 12:23:14 GMT

←Older revision		Revision as of 12:23, 12 October 2017
Line 1:		Line 1:
		+
	==Sweet potato purple acid phosphatase/phosphate complex==		==Sweet potato purple acid phosphatase/phosphate complex==
	<StructureSection load='1xzw' size='340' side='right' caption='[[1xzw]], [[Resolution\|resolution]] 2.50Å' scene=''>		<StructureSection load='1xzw' size='340' side='right' caption='[[1xzw]], [[Resolution\|resolution]] 2.50Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1xzw]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Ipomoea_batatas Ipomoea~~ batatas]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XZW OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1XZW FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1xzw]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Convolvulus_batatas Convolvulus batatas]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XZW OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1XZW FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=MN:~~MANGANESE+(II)+ION~~'>MN</scene>, <scene name='pdbligand=~~NAG~~:~~N-ACETYL~~-D-~~GLUCOSAMINE~~'>~~NAG~~</scene>, <scene name='pdbligand=~~PO4~~:~~PHOSPHATE~~+ION'>~~PO4~~</scene>, <scene name='pdbligand=~~FUC~~:~~ALPHA~~-L-~~FUCOSE~~'>~~FUC~~</scene>, <scene name='pdbligand=~~MAN~~:~~ALPHA-D-MANNOSE~~'>~~MAN~~</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=FUC:ALPHA-L-FUCOSE'>FUC</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1ute\|1ute]], [[4kbp\|4kbp]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1ute\|1ute]], [[4kbp\|4kbp]]</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Acid_phosphatase Acid phosphatase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.3.2 3.1.3.2] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Acid_phosphatase Acid phosphatase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.3.2 3.1.3.2] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1xzw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1xzw OCA], [http://pdbe.org/1xzw PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1xzw RCSB], [http://www.ebi.ac.uk/pdbsum/1xzw PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1xzw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1xzw OCA], [http://pdbe.org/1xzw PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1xzw RCSB], [http://www.ebi.ac.uk/pdbsum/1xzw PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1xzw ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 27:		Line 28:
	</div>		</div>
	<div class="pdbe-citations 1xzw" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 1xzw" style="background-color:#fffaf0;"></div>
-
-	==See Also==
-	*[[Acid phosphatase\|Acid phosphatase]]
	== References ==		== References ==
	<references/>		<references/>
Line 35:		Line 33:
	</StructureSection>		</StructureSection>
	[[Category: Acid phosphatase]]		[[Category: Acid phosphatase]]
-	[[Category: ~~Ipomoea~~ batatas]]	+	[[Category: Convolvulus batatas]]
	[[Category: Carrington, L E]]		[[Category: Carrington, L E]]
	[[Category: Gahan, L R]]		[[Category: Gahan, L R]]

OCA at 16:15, 9 February 2016

OCA — Tue, 09 Feb 2016 16:15:43 GMT

←Older revision		Revision as of 16:15, 9 February 2016
Line 16:		Line 16:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1xzw ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 23:56, 10 September 2015

OCA — Thu, 10 Sep 2015 23:56:20 GMT

←Older revision		Revision as of 23:56, 10 September 2015
Line 6:		Line 6:
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1ute\|1ute]], [[4kbp\|4kbp]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1ute\|1ute]], [[4kbp\|4kbp]]</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Acid_phosphatase Acid phosphatase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.3.2 3.1.3.2] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Acid_phosphatase Acid phosphatase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.3.2 3.1.3.2] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1xzw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1xzw OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1xzw RCSB], [http://www.ebi.ac.uk/pdbsum/1xzw PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1xzw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1xzw OCA], [http://pdbe.org/1xzw PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1xzw RCSB], [http://www.ebi.ac.uk/pdbsum/1xzw PDBsum]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 26:		Line 26:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 1xzw" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==

OCA at 08:53, 8 January 2015

OCA — Thu, 08 Jan 2015 08:53:01 GMT

←Older revision		Revision as of 08:53, 8 January 2015
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1xzw]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Ipomoea_batatas Ipomoea batatas]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XZW OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1XZW FirstGlance]. <br>		<table><tr><td colspan='2'>[[1xzw]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Ipomoea_batatas Ipomoea batatas]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XZW OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1XZW FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=FUC:ALPHA-L-FUCOSE'>FUC</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene><br>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=FUC:ALPHA-L-FUCOSE'>FUC</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene></td></tr>
-	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1ute\|1ute]], [[4kbp\|4kbp]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1ute\|1ute]], [[4kbp\|4kbp]]</td></tr>
-	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Acid_phosphatase Acid phosphatase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.3.2 3.1.3.2] </span></td></tr>	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Acid_phosphatase Acid phosphatase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.3.2 3.1.3.2] </span></td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1xzw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1xzw OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1xzw RCSB], [http://www.ebi.ac.uk/pdbsum/1xzw PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1xzw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1xzw OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1xzw RCSB], [http://www.ebi.ac.uk/pdbsum/1xzw PDBsum]</span></td></tr>
-	<table>	+	</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 35:		Line 35:
	[[Category: Acid phosphatase]]		[[Category: Acid phosphatase]]
	[[Category: Ipomoea batatas]]		[[Category: Ipomoea batatas]]
-	[[Category: Carrington, L E.]]	+	[[Category: Carrington, L E]]
-	[[Category: Gahan, L R.]]	+	[[Category: Gahan, L R]]
-	[[Category: Guddat, L W.]]	+	[[Category: Guddat, L W]]
-	[[Category: Hamilton, S E.]]	+	[[Category: Hamilton, S E]]
-	[[Category: Jersey, J de.]]	+	[[Category: Jersey, J de]]
-	[[Category: Schenk, G.]]	+	[[Category: Schenk, G]]
	[[Category: Hydrolase]]		[[Category: Hydrolase]]

OCA at 20:46, 28 September 2014

OCA — Sun, 28 Sep 2014 20:46:57 GMT

←Older revision		Revision as of 20:46, 28 September 2014
Line 1:		Line 1:
-	[[~~Image:~~1xzw.~~png~~\|~~left~~\|200px]]	+	==Sweet potato purple acid phosphatase/phosphate complex==
		+	<StructureSection load='1xzw' size='340' side='right' caption='[[1xzw]], [[Resolution\|resolution]] 2.50Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[1xzw]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Ipomoea_batatas Ipomoea batatas]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XZW OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1XZW FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=FUC:ALPHA-L-FUCOSE'>FUC</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene><br>
		+	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1ute\|1ute]], [[4kbp\|4kbp]]</td></tr>
		+	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Acid_phosphatase Acid phosphatase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.3.2 3.1.3.2] </span></td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1xzw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1xzw OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1xzw RCSB], [http://www.ebi.ac.uk/pdbsum/1xzw PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/xz/1xzw_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Purple acid phosphatases (PAPs) are a family of binuclear metalloenzymes that catalyze the hydrolysis of phosphoric acid esters and anhydrides. A PAP in sweet potato has a unique, strongly antiferromagnetically coupled Fe(III)-Mn(II) center and is distinguished from other PAPs by its increased catalytic efficiency for a range of activated and unactivated phosphate esters, its strict requirement for Mn(II), and the presence of a mu-oxo bridge at pH 4.90. This enzyme displays maximum catalytic efficiency (k(cat)/K(m)) at pH 4.5, whereas its catalytic rate constant (k(cat)) is maximal at near-neutral pH, and, in contrast to other PAPs, its catalytic parameters are not dependent on the pK(a) of the leaving group. The crystal structure of the phosphate-bound Fe(III)-Mn(II) PAP has been determined to 2.5-A resolution (final R(free) value of 0.256). Structural comparisons of the active site of sweet potato, red kidney bean, and mammalian PAPs show several amino acid substitutions in the sweet potato enzyme that can account for its increased catalytic efficiency. The phosphate molecule binds in an unusual tripodal mode to the two metal ions, with two of the phosphate oxygen atoms binding to Fe(III) and Mn(II), a third oxygen atom bridging the two metal ions, and the fourth oxygen pointing toward the substrate binding pocket. This binding mode is unique among the known structures in this family but is reminiscent of phosphate binding to urease and of sulfate binding to lambda protein phosphatase. The structure and kinetics support the hypothesis that the bridging oxygen atom initiates hydrolysis.

-	~~{{STRUCTURE_1xzw\| PDB=1xzw \| SCENE= }}~~	+	Phosphate forms an unusual tripodal complex with the Fe-Mn center of sweet potato purple acid phosphatase.,Schenk G, Gahan LR, Carrington LE, Mitic N, Valizadeh M, Hamilton SE, de Jersey J, Guddat LW Proc Natl Acad Sci U S A. 2005 Jan 11;102(2):273-8. Epub 2004 Dec 29. PMID:15625111<ref>PMID:15625111</ref>

-	~~===Sweet potato purple acid phosphatase~~/~~phosphate complex===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_15625111}}~~	+
-		+
-	~~==About this Structure==~~	+
-	~~[[1xzw]] is~~ a ~~2 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Ipomoea_batatas Ipomoea batatas]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=1XZW OCA].~~	+

	==See Also==		==See Also==
	*[[Acid phosphatase\|Acid phosphatase]]		*[[Acid phosphatase\|Acid phosphatase]]
-		+	== References ==
-	==~~Reference~~==	+	<references/>
-	<~~ref group="xtra">PMID:015625111<~~/~~ref~~><~~references group="xtra"~~/>	+	__TOC__
		+	</StructureSection>
	[[Category: Acid phosphatase]]		[[Category: Acid phosphatase]]
	[[Category: Ipomoea batatas]]		[[Category: Ipomoea batatas]]

OCA at 14:25, 20 October 2012

OCA — Sat, 20 Oct 2012 14:25:13 GMT

←Older revision		Revision as of 14:25, 20 October 2012
Line 8:		Line 8:

	==About this Structure==		==About this Structure==
-	[[1xzw]] is a 2 chain structure ~~of [[Acid phosphatase]]~~ with sequence from [http://en.wikipedia.org/wiki/Ipomoea_batatas Ipomoea batatas]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XZW OCA].	+	[[1xzw]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Ipomoea_batatas Ipomoea batatas]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XZW OCA].

	==See Also==		==See Also==

OCA: Protected "1xzw" [edit=sysop:move=sysop]

OCA — Thu, 26 Jul 2012 15:04:47 GMT

Protected "1xzw" [edit=sysop:move=sysop]

←Older revision

Revision as of 15:04, 26 July 2012