1y2y - Revision history

OCA at 08:00, 15 May 2024

OCA — Wed, 15 May 2024 08:00:08 GMT

←Older revision		Revision as of 08:00, 15 May 2024
Line 1:		Line 1:

	==Structural Characterization of Nop10p using Nuclear Magnetic Resonance Spectroscopy==		==Structural Characterization of Nop10p using Nuclear Magnetic Resonance Spectroscopy==
-	<StructureSection load='1y2y' size='340' side='right'caption='[[1y2y~~]], [[NMR_Ensembles_of_Models \| 10 NMR models~~]]' scene=''>	+	<StructureSection load='1y2y' size='340' side='right'caption='[[1y2y]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1y2y]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Atcc_18824 Atcc 18824~~]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Y2Y OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1Y2Y FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1y2y]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Y2Y OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1Y2Y FirstGlance]. <br>
-	</td></tr><tr id='~~gene~~'><td class="sblockLbl"><b>[[~~Gene~~\|~~Gene~~:]]</b></td><td class="sblockDat"~~>NOP10 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&~~id=~~4932 ATCC 18824])~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1y2y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1y2y OCA], [https://pdbe.org/1y2y PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1y2y RCSB], [https://www.ebi.ac.uk/pdbsum/1y2y PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1y2y ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1y2y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1y2y OCA], [https://pdbe.org/1y2y PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1y2y RCSB], [https://www.ebi.ac.uk/pdbsum/1y2y PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1y2y ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[https://www.uniprot.org/uniprot/NOP10_YEAST NOP10_YEAST]] Required for ribosome biogenesis. Part of a complex which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ("psi") residues may serve to stabilize the conformation of rRNAs. Essential for growth.<ref>PMID:9843512</ref>	+	[https://www.uniprot.org/uniprot/NOP10_YEAST NOP10_YEAST] Required for ribosome biogenesis. Part of a complex which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ("psi") residues may serve to stabilize the conformation of rRNAs. Essential for growth.<ref>PMID:9843512</ref>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 30:		Line 30:

	==See Also==		==See Also==
-	*[[Ribosome biogenesis protein\|Ribosome biogenesis protein]]	+	*[[Ribosome biogenesis protein 3D structures\|Ribosome biogenesis protein 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Atcc 18824]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Caizergues-Ferrer, M]]	+	[[Category: Saccharomyces cerevisiae]]
-	[[Category: Feigon, J]]	+	[[Category: Caizergues-Ferrer M]]
-	[[Category: Johansson, C]]	+	[[Category: Feigon J]]
-	[[Category: Khanna, M]]	+	[[Category: Johansson C]]
-	[[Category: Wu, H]]	+	[[Category: Khanna M]]
-	~~[[Category: Biosynthetic protein]]~~	+	[[Category: Wu H]]
-	~~[[Category: Box h/aca snorna]]~~	+
-	~~[[Category: Pseudouridine]]~~	+
-	~~[[Category: Snornp~~]]	+

OCA at 07:11, 2 March 2022

OCA — Wed, 02 Mar 2022 07:11:02 GMT

←Older revision		Revision as of 07:11, 2 March 2022
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	<StructureSection load='1y2y' size='340' side='right'caption='[[1y2y]], [[NMR_Ensembles_of_Models \| 10 NMR models]]' scene=''>		<StructureSection load='1y2y' size='340' side='right'caption='[[1y2y]], [[NMR_Ensembles_of_Models \| 10 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1y2y]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Atcc_18824 Atcc 18824]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Y2Y OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=1Y2Y FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1y2y]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Atcc_18824 Atcc 18824]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Y2Y OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1Y2Y FirstGlance]. <br>
-	</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">NOP10 ([~~http~~://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=4932 ATCC 18824])</td></tr>	+	</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">NOP10 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=4932 ATCC 18824])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=1y2y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1y2y OCA], [~~http~~://pdbe.org/1y2y PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=1y2y RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/1y2y PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=1y2y ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1y2y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1y2y OCA], [https://pdbe.org/1y2y PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1y2y RCSB], [https://www.ebi.ac.uk/pdbsum/1y2y PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1y2y ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[~~http~~://www.uniprot.org/uniprot/NOP10_YEAST NOP10_YEAST]] Required for ribosome biogenesis. Part of a complex which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ("psi") residues may serve to stabilize the conformation of rRNAs. Essential for growth.<ref>PMID:9843512</ref>	+	[[https://www.uniprot.org/uniprot/NOP10_YEAST NOP10_YEAST]] Required for ribosome biogenesis. Part of a complex which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ("psi") residues may serve to stabilize the conformation of rRNAs. Essential for growth.<ref>PMID:9843512</ref>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]

OCA at 10:31, 6 January 2021

OCA — Wed, 06 Jan 2021 10:31:33 GMT

←Older revision		Revision as of 10:31, 6 January 2021
Line 1:		Line 1:

	==Structural Characterization of Nop10p using Nuclear Magnetic Resonance Spectroscopy==		==Structural Characterization of Nop10p using Nuclear Magnetic Resonance Spectroscopy==
-	<StructureSection load='1y2y' size='340' side='right' caption='[[1y2y]], [[NMR_Ensembles_of_Models \| 10 NMR models]]' scene=''>	+	<StructureSection load='1y2y' size='340' side='right'caption='[[1y2y]], [[NMR_Ensembles_of_Models \| 10 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1y2y]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_18824 Atcc 18824]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Y2Y OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1Y2Y FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1y2y]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_18824 Atcc 18824]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Y2Y OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=1Y2Y FirstGlance]. <br>
	</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">NOP10 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=4932 ATCC 18824])</td></tr>		</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">NOP10 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=4932 ATCC 18824])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1y2y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1y2y OCA], [http://pdbe.org/1y2y PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1y2y RCSB], [http://www.ebi.ac.uk/pdbsum/1y2y PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1y2y ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=1y2y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1y2y OCA], [http://pdbe.org/1y2y PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1y2y RCSB], [http://www.ebi.ac.uk/pdbsum/1y2y PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1y2y ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 36:		Line 36:
	</StructureSection>		</StructureSection>
	[[Category: Atcc 18824]]		[[Category: Atcc 18824]]
		+	[[Category: Large Structures]]
	[[Category: Caizergues-Ferrer, M]]		[[Category: Caizergues-Ferrer, M]]
	[[Category: Feigon, J]]		[[Category: Feigon, J]]

OCA at 07:30, 18 April 2018

OCA — Wed, 18 Apr 2018 07:30:25 GMT

←Older revision		Revision as of 07:30, 18 April 2018
Line 1:		Line 1:
		+
	==Structural Characterization of Nop10p using Nuclear Magnetic Resonance Spectroscopy==		==Structural Characterization of Nop10p using Nuclear Magnetic Resonance Spectroscopy==
	<StructureSection load='1y2y' size='340' side='right' caption='[[1y2y]], [[NMR_Ensembles_of_Models \| 10 NMR models]]' scene=''>		<StructureSection load='1y2y' size='340' side='right' caption='[[1y2y]], [[NMR_Ensembles_of_Models \| 10 NMR models]]' scene=''>
Line 4:		Line 5:
	<table><tr><td colspan='2'>[[1y2y]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_18824 Atcc 18824]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Y2Y OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1Y2Y FirstGlance]. <br>		<table><tr><td colspan='2'>[[1y2y]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_18824 Atcc 18824]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Y2Y OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1Y2Y FirstGlance]. <br>
	</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">NOP10 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=4932 ATCC 18824])</td></tr>		</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">NOP10 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=4932 ATCC 18824])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1y2y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1y2y OCA], [http://pdbe.org/1y2y PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1y2y RCSB], [http://www.ebi.ac.uk/pdbsum/1y2y PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1y2y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1y2y OCA], [http://pdbe.org/1y2y PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1y2y RCSB], [http://www.ebi.ac.uk/pdbsum/1y2y PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1y2y ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
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	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/y2/1y2y_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/y2/1y2y_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
Line 27:		Line 28:
	</div>		</div>
	<div class="pdbe-citations 1y2y" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 1y2y" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[Ribosome biogenesis protein\|Ribosome biogenesis protein]]
	== References ==		== References ==
	<references/>		<references/>

OCA at 01:22, 8 February 2016

OCA — Mon, 08 Feb 2016 01:22:07 GMT

←Older revision		Revision as of 01:22, 8 February 2016
Line 16:		Line 16:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1y2y ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 06:34, 10 September 2015

OCA — Thu, 10 Sep 2015 06:34:01 GMT

←Older revision		Revision as of 06:34, 10 September 2015
Line 2:		Line 2:
	<StructureSection load='1y2y' size='340' side='right' caption='[[1y2y]], [[NMR_Ensembles_of_Models \| 10 NMR models]]' scene=''>		<StructureSection load='1y2y' size='340' side='right' caption='[[1y2y]], [[NMR_Ensembles_of_Models \| 10 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1y2y]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Saccharomyces_cerevisiae Saccharomyces cerevisiae~~]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Y2Y OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1Y2Y FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1y2y]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_18824 Atcc 18824]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Y2Y OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1Y2Y FirstGlance]. <br>
-	</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">NOP10 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=4932 ~~Saccharomyces cerevisiae~~])</td></tr>	+	</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">NOP10 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=4932 ATCC 18824])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1y2y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1y2y OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1y2y RCSB], [http://www.ebi.ac.uk/pdbsum/1y2y PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1y2y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1y2y OCA], [http://pdbe.org/1y2y PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1y2y RCSB], [http://www.ebi.ac.uk/pdbsum/1y2y PDBsum]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 26:		Line 26:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 1y2y" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Saccharomyces cerevisiae~~]]	+	[[Category: Atcc 18824]]
	[[Category: Caizergues-Ferrer, M]]		[[Category: Caizergues-Ferrer, M]]
	[[Category: Feigon, J]]		[[Category: Feigon, J]]

OCA at 19:32, 24 December 2014

OCA — Wed, 24 Dec 2014 19:32:06 GMT

←Older revision		Revision as of 19:32, 24 December 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1y2y]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Y2Y OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1Y2Y FirstGlance]. <br>		<table><tr><td colspan='2'>[[1y2y]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Y2Y OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1Y2Y FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">NOP10 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=4932 Saccharomyces cerevisiae])</td></tr>	+	</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">NOP10 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=4932 Saccharomyces cerevisiae])</td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1y2y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1y2y OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1y2y RCSB], [http://www.ebi.ac.uk/pdbsum/1y2y PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1y2y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1y2y OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1y2y RCSB], [http://www.ebi.ac.uk/pdbsum/1y2y PDBsum]</span></td></tr>
-	<table>	+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/NOP10_YEAST NOP10_YEAST]] Required for ribosome biogenesis. Part of a complex which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ("psi") residues may serve to stabilize the conformation of rRNAs. Essential for growth.<ref>PMID:9843512</ref>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 29:		Line 31:
	</StructureSection>		</StructureSection>
	[[Category: Saccharomyces cerevisiae]]		[[Category: Saccharomyces cerevisiae]]
-	[[Category: Caizergues-Ferrer, M.]]	+	[[Category: Caizergues-Ferrer, M]]
-	[[Category: Feigon, J.]]	+	[[Category: Feigon, J]]
-	[[Category: Johansson, C.]]	+	[[Category: Johansson, C]]
-	[[Category: Khanna, M.]]	+	[[Category: Khanna, M]]
-	[[Category: Wu, H.]]	+	[[Category: Wu, H]]
	[[Category: Biosynthetic protein]]		[[Category: Biosynthetic protein]]
	[[Category: Box h/aca snorna]]		[[Category: Box h/aca snorna]]
	[[Category: Pseudouridine]]		[[Category: Pseudouridine]]
	[[Category: Snornp]]		[[Category: Snornp]]

OCA at 20:09, 29 September 2014

OCA — Mon, 29 Sep 2014 20:09:20 GMT

←Older revision		Revision as of 20:09, 29 September 2014
Line 1:		Line 1:
-	[[~~Image~~:1y2y.~~png\|left~~\|200px]]	+	==Structural Characterization of Nop10p using Nuclear Magnetic Resonance Spectroscopy==
		+	<StructureSection load='1y2y' size='340' side='right' caption='[[1y2y]], [[NMR_Ensembles_of_Models \| 10 NMR models]]' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[1y2y]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Y2Y OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1Y2Y FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">NOP10 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=4932 Saccharomyces cerevisiae])</td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1y2y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1y2y OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1y2y RCSB], [http://www.ebi.ac.uk/pdbsum/1y2y PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/y2/1y2y_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	The H/ACA small nucleolar ribonucleoprotein (snoRNP) complexes guide the modification of uridine to pseudouridine at conserved sites in rRNA. The H/ACA snoRNPs each comprise a target-site-specific snoRNA and four core proteins, Nop10p, Nhp2p, Gar1p, and the pseudouridine synthase, Cbf5p, in yeast. The secondary structure of the H/ACA snoRNAs includes two hairpins that each contain a large internal loop (the pseudouridylation pocket), one or both of which are partially complementary to the target RNA(s). We have determined the solution structure of an RNA hairpin derived from the human U65 box H/ACA snoRNA including the pseudouridylation pocket and adjacent stems, providing the first three-dimensional structural information on these H/ACA snoRNAs. We have also determined the structure of Nop10p and investigated its interaction with RNA using NMR spectroscopy. Nop10p contains a structurally well-defined N-terminal region composed of a beta-hairpin, and the rest of the protein lacks a globular structure. Chemical shift mapping of the interaction of RNA constructs of U65 box H/ACA 3' hairpin with Nop10p shows that the beta-hairpin binds weakly but specifically to RNA. The unstructured region of Nop10p likely interacts with Cbf5p.

-	~~{{STRUCTURE_1y2y\| PDB=1y2y \| SCENE= }}~~	+	Structural study of the H/ACA snoRNP components Nop10p and the 3' hairpin of U65 snoRNA.,Khanna M, Wu H, Johansson C, Caizergues-Ferrer M, Feigon J RNA. 2006 Jan;12(1):40-52. PMID:16373493<ref>PMID:16373493</ref>

-	~~===Structural Characterization~~ of ~~Nop10p using Nuclear Magnetic Resonance Spectroscopy===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_16373493}}~~	+	== References ==
-		+	<references/>
-	~~==About this Structure==~~	+	__TOC__
-	~~[[1y2y]] is a 1 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]~~. ~~Full experimental information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=1Y2Y OCA].~~	+	</StructureSection>
-		+
-	==~~Reference~~==	+
-	<~~ref group="xtra">PMID:016373493<~~/~~ref~~><~~references group="xtra"~~/>	+
	[[Category: Saccharomyces cerevisiae]]		[[Category: Saccharomyces cerevisiae]]
	[[Category: Caizergues-Ferrer, M.]]		[[Category: Caizergues-Ferrer, M.]]

OCA: Protected "1y2y" [edit=sysop:move=sysop]

OCA — Sat, 05 Jan 2013 13:41:33 GMT

Protected "1y2y" [edit=sysop:move=sysop]

←Older revision

Revision as of 13:41, 5 January 2013

OCA at 13:41, 5 January 2013

OCA — Sat, 05 Jan 2013 13:41:30 GMT

←Older revision		Revision as of 13:41, 5 January 2013
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-	{{Seed}}
	[[Image:1y2y.png\|left\|200px]]		[[Image:1y2y.png\|left\|200px]]

-	<!--
-	The line below this paragraph, containing "STRUCTURE_1y2y", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_1y2y\| PDB=1y2y \| SCENE= }}		{{STRUCTURE_1y2y\| PDB=1y2y \| SCENE= }}

	===Structural Characterization of Nop10p using Nuclear Magnetic Resonance Spectroscopy===		===Structural Characterization of Nop10p using Nuclear Magnetic Resonance Spectroscopy===

-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_16373493}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where 16373493 is the PubMed ID number.
-	-->
	{{ABSTRACT_PUBMED_16373493}}		{{ABSTRACT_PUBMED_16373493}}

	==About this Structure==		==About this Structure==
-	~~1Y2Y~~ is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Y2Y OCA].	+	[[1y2y]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Y2Y OCA].

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~16373493~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:016373493</ref><references group="xtra"/>
	[[Category: Saccharomyces cerevisiae]]		[[Category: Saccharomyces cerevisiae]]
	[[Category: Caizergues-Ferrer, M.]]		[[Category: Caizergues-Ferrer, M.]]
Line 30:		Line 18:
	[[Category: Khanna, M.]]		[[Category: Khanna, M.]]
	[[Category: Wu, H.]]		[[Category: Wu, H.]]
-	[[Category: Box h/aca snorna~~,snornp~~]]	+	[[Category: Biosynthetic protein]]
		+	[[Category: Box h/aca snorna]]
	[[Category: Pseudouridine]]		[[Category: Pseudouridine]]
-		+	[[Category: Snornp]]
-	~~''Page seeded by~~ [~~http~~:~~//oca.weizmann.ac.il/oca OCA~~ ] ~~on Mon Feb 16 17:47:06 2009''~~	+