1yj6 - Revision history

OCA at 06:57, 23 August 2023

OCA — Wed, 23 Aug 2023 06:57:39 GMT

←Older revision		Revision as of 06:57, 23 August 2023
Line 3:		Line 3:
	<StructureSection load='1yj6' size='340' side='right'caption='[[1yj6]], [[Resolution\|resolution]] 2.50Å' scene=''>		<StructureSection load='1yj6' size='340' side='right'caption='[[1yj6]], [[Resolution\|resolution]] 2.50Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1yj6]] is a 3 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Human Human~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YJ6 OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=1YJ6 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1yj6]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YJ6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1YJ6 FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=GSH:GLUTATHIONE'>GSH</scene>~~, ~~<scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>~~	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.5Å</td></tr>
-	~~<tr id='related'><td class="sblockLbl"><b>~~[[~~Related_structure~~\|~~Related:~~]]~~</b></td><td class="sblockDat"><div style='overflow: auto~~; ~~max-height: 3em;'>[[1gtu\|1gtu]], [[1xw6\|1xw6]], [[1xwk\|1xwk]]</div>~~</td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GSH:GLUTATHIONE'>GSH</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
-	<tr id='~~gene~~'><td class="sblockLbl"><b>[[~~Gene~~\|~~Gene~~:]]</b></td><td class="sblockDat"~~>GSTM1, GST1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&~~id=~~9606 HUMAN])</td~~><~~/tr>~~	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1yj6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1yj6 OCA], [https://pdbe.org/1yj6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1yj6 RCSB], [https://www.ebi.ac.uk/pdbsum/1yj6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1yj6 ProSAT]</span></td></tr>
-	~~<tr id~~='~~activity'><td class~~=~~"sblockLbl"><b>Activity~~:~~</b~~></td><~~td class~~=~~"sblockDat"><span class~~=~~'plainlinks~~'>~~[http://en.wikipedia.org/wiki/Glutathione_transferase Glutathione transferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.5.1.18 2.5.1.18]~~ </~~span~~></td></tr>	+
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=1yj6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1yj6 OCA], [~~http~~://pdbe.org/1yj6 PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=1yj6 RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/1yj6 PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=1yj6 ProSAT]</span></td></tr>	+
	</table>		</table>
	== Function ==		== Function ==
-	[~~[http~~://www.uniprot.org/uniprot/GSTM1_HUMAN GSTM1_HUMAN]] Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles.<ref>PMID:16548513</ref>	+	[https://www.uniprot.org/uniprot/GSTM1_HUMAN GSTM1_HUMAN] Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles.<ref>PMID:16548513</ref>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 29:		Line 27:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Glutathione transferase]]~~	+	[[Category: Homo sapiens]]
-	~~[[Category: Human~~]]	+
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Almo~~, S C~~]]	+	[[Category: Almo SC]]
-	[[Category: Listowsky, I]]	+	[[Category: Listowsky I]]
-	[[Category: Patskovska~~, L N~~]]	+	[[Category: Patskovska LN]]
-	[[Category: Patskovsky~~, Y V]]~~	+	[[Category: Patskovsky YV]]
-	~~[[Category: Active site]]~~	+
-	~~[[Category: Conjugation]]~~	+
-	~~[[Category: Coordination complex]]~~	+
-	~~[[Category: Cytosolic]]~~	+
-	~~[[Category: Detoxification]]~~	+
-	~~[[Category: Dimer]]~~	+
-	~~[[Category: Glutathione]]~~	+
-	~~[[Category: Transferase]]~~	+
-	~~[[Category: Zinc~~]]	+

OCA at 08:46, 20 January 2021

OCA — Wed, 20 Jan 2021 08:46:46 GMT

←Older revision		Revision as of 08:46, 20 January 2021
Line 1:		Line 1:

	==crystal structure of human glutathione S-transferase M1A-1A complexed with glutathionyl-zinc-trihydroxide==		==crystal structure of human glutathione S-transferase M1A-1A complexed with glutathionyl-zinc-trihydroxide==
-	<StructureSection load='1yj6' size='340' side='right' caption='[[1yj6]], [[Resolution\|resolution]] 2.50Å' scene=''>	+	<StructureSection load='1yj6' size='340' side='right'caption='[[1yj6]], [[Resolution\|resolution]] 2.50Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1yj6]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YJ6 OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1YJ6 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1yj6]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YJ6 OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=1YJ6 FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GSH:GLUTATHIONE'>GSH</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GSH:GLUTATHIONE'>GSH</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1gtu\|1gtu]], [[1xw6\|1xw6]], [[1xwk\|1xwk]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1gtu\|1gtu]], [[1xw6\|1xw6]], [[1xwk\|1xwk]]</div></td></tr>
	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">GSTM1, GST1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">GSTM1, GST1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glutathione_transferase Glutathione transferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.5.1.18 2.5.1.18] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glutathione_transferase Glutathione transferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.5.1.18 2.5.1.18] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1yj6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1yj6 OCA], [http://pdbe.org/1yj6 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1yj6 RCSB], [http://www.ebi.ac.uk/pdbsum/1yj6 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1yj6 ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=1yj6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1yj6 OCA], [http://pdbe.org/1yj6 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1yj6 RCSB], [http://www.ebi.ac.uk/pdbsum/1yj6 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1yj6 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 16:		Line 16:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/yj/1yj6_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/yj/1yj6_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
Line 22:		Line 22:
	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1yj6 ConSurf].		</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1yj6 ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
		+
		+	==See Also==
		+	*[[Glutathione S-transferase 3D structures\|Glutathione S-transferase 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
Line 28:		Line 31:
	[[Category: Glutathione transferase]]		[[Category: Glutathione transferase]]
	[[Category: Human]]		[[Category: Human]]
		+	[[Category: Large Structures]]
	[[Category: Almo, S C]]		[[Category: Almo, S C]]
	[[Category: Listowsky, I]]		[[Category: Listowsky, I]]

OCA at 15:52, 12 October 2017

OCA — Thu, 12 Oct 2017 15:52:36 GMT

←Older revision		Revision as of 15:52, 12 October 2017
Line 1:		Line 1:
		+
	==crystal structure of human glutathione S-transferase M1A-1A complexed with glutathionyl-zinc-trihydroxide==		==crystal structure of human glutathione S-transferase M1A-1A complexed with glutathionyl-zinc-trihydroxide==
	<StructureSection load='1yj6' size='340' side='right' caption='[[1yj6]], [[Resolution\|resolution]] 2.50Å' scene=''>		<StructureSection load='1yj6' size='340' side='right' caption='[[1yj6]], [[Resolution\|resolution]] 2.50Å' scene=''>
Line 7:		Line 8:
	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">GSTM1, GST1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">GSTM1, GST1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glutathione_transferase Glutathione transferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.5.1.18 2.5.1.18] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glutathione_transferase Glutathione transferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.5.1.18 2.5.1.18] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1yj6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1yj6 OCA], [http://pdbe.org/1yj6 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1yj6 RCSB], [http://www.ebi.ac.uk/pdbsum/1yj6 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1yj6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1yj6 OCA], [http://pdbe.org/1yj6 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1yj6 RCSB], [http://www.ebi.ac.uk/pdbsum/1yj6 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1yj6 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
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	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1yj6 ConSurf].		</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1yj6 ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
-
-	==See Also==
-	*[[Glutathione S-transferase\|Glutathione S-transferase]]
	== References ==		== References ==
	<references/>		<references/>
Line 42:		Line 40:
	[[Category: Glutathione]]		[[Category: Glutathione]]
	[[Category: Transferase]]		[[Category: Transferase]]
		+	[[Category: Zinc]]

OCA at 08:18, 10 February 2016

OCA — Wed, 10 Feb 2016 08:18:50 GMT

←Older revision		Revision as of 08:18, 10 February 2016
Line 19:		Line 19:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1yj6 ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>

OCA at 07:02, 11 September 2015

OCA — Fri, 11 Sep 2015 07:02:02 GMT

←Older revision		Revision as of 07:02, 11 September 2015
Line 2:		Line 2:
	<StructureSection load='1yj6' size='340' side='right' caption='[[1yj6]], [[Resolution\|resolution]] 2.50Å' scene=''>		<StructureSection load='1yj6' size='340' side='right' caption='[[1yj6]], [[Resolution\|resolution]] 2.50Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1yj6]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Homo_sapiens Homo sapiens~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YJ6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1YJ6 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1yj6]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YJ6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1YJ6 FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GSH:GLUTATHIONE'>GSH</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GSH:GLUTATHIONE'>GSH</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1gtu\|1gtu]], [[1xw6\|1xw6]], [[1xwk\|1xwk]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1gtu\|1gtu]], [[1xw6\|1xw6]], [[1xwk\|1xwk]]</td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">GSTM1, GST1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 ~~Homo sapiens~~])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">GSTM1, GST1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glutathione_transferase Glutathione transferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.5.1.18 2.5.1.18] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glutathione_transferase Glutathione transferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.5.1.18 2.5.1.18] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1yj6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1yj6 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1yj6 RCSB], [http://www.ebi.ac.uk/pdbsum/1yj6 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1yj6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1yj6 OCA], [http://pdbe.org/1yj6 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1yj6 RCSB], [http://www.ebi.ac.uk/pdbsum/1yj6 PDBsum]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 29:		Line 29:
	</StructureSection>		</StructureSection>
	[[Category: Glutathione transferase]]		[[Category: Glutathione transferase]]
-	[[Category: ~~Homo sapiens~~]]	+	[[Category: Human]]
	[[Category: Almo, S C]]		[[Category: Almo, S C]]
	[[Category: Listowsky, I]]		[[Category: Listowsky, I]]

OCA at 12:57, 25 December 2014

OCA — Thu, 25 Dec 2014 12:57:14 GMT

←Older revision		Revision as of 12:57, 25 December 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1yj6]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YJ6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1YJ6 FirstGlance]. <br>		<table><tr><td colspan='2'>[[1yj6]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YJ6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1YJ6 FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GSH:GLUTATHIONE'>GSH</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene><br>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GSH:GLUTATHIONE'>GSH</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
-	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1gtu\|1gtu]], [[1xw6\|1xw6]], [[1xwk\|1xwk]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1gtu\|1gtu]], [[1xw6\|1xw6]], [[1xwk\|1xwk]]</td></tr>
-	<tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">GSTM1, GST1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">GSTM1, GST1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>
-	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glutathione_transferase Glutathione transferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.5.1.18 2.5.1.18] </span></td></tr>	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glutathione_transferase Glutathione transferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.5.1.18 2.5.1.18] </span></td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1yj6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1yj6 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1yj6 RCSB], [http://www.ebi.ac.uk/pdbsum/1yj6 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1yj6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1yj6 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1yj6 RCSB], [http://www.ebi.ac.uk/pdbsum/1yj6 PDBsum]</span></td></tr>
-	<table>	+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/GSTM1_HUMAN GSTM1_HUMAN]] Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles.<ref>PMID:16548513</ref>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 22:		Line 24:
	==See Also==		==See Also==
	*[[Glutathione S-transferase\|Glutathione S-transferase]]		*[[Glutathione S-transferase\|Glutathione S-transferase]]
		+	== References ==
		+	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: Glutathione transferase]]		[[Category: Glutathione transferase]]
	[[Category: Homo sapiens]]		[[Category: Homo sapiens]]
-	[[Category: Almo, S C.]]	+	[[Category: Almo, S C]]
-	[[Category: Listowsky, I.]]	+	[[Category: Listowsky, I]]
-	[[Category: Patskovska, L N.]]	+	[[Category: Patskovska, L N]]
-	[[Category: Patskovsky, Y V.]]	+	[[Category: Patskovsky, Y V]]
	[[Category: Active site]]		[[Category: Active site]]
	[[Category: Conjugation]]		[[Category: Conjugation]]

OCA at 20:02, 29 September 2014

OCA — Mon, 29 Sep 2014 20:02:52 GMT

←Older revision		Revision as of 20:02, 29 September 2014
Line 1:		Line 1:
-	~~[[Image:1yj6.png\|left\|200px]]~~	+	==crystal structure of human glutathione S-transferase M1A-1A complexed with glutathionyl-zinc-trihydroxide==
-		+	<StructureSection load='1yj6' size='340' side='right' caption='[[1yj6]], [[Resolution\|resolution]] 2.50Å' scene=''>
-	~~{{STRUCTURE_1yj6\| PDB=1yj6 \| SCENE= }}~~	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[1yj6]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YJ6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1YJ6 FirstGlance]. <br>
-	===crystal structure of human glutathione S-transferase M1A-1A complexed with glutathionyl-zinc-trihydroxide===	+	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GSH:GLUTATHIONE'>GSH</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene><br>
-		+	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1gtu\|1gtu]], [[1xw6\|1xw6]], [[1xwk\|1xwk]]</td></tr>
-		+	<tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">GSTM1, GST1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>
-	==~~About this Structure~~==	+	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glutathione_transferase Glutathione transferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.5.1.18 2.5.1.18] </span></td></tr>
-	[[1yj6]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YJ6 OCA].	+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1yj6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1yj6 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1yj6 RCSB], [http://www.ebi.ac.uk/pdbsum/1yj6 PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/yj/1yj6_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>

	==See Also==		==See Also==
	*[[Glutathione S-transferase\|Glutathione S-transferase]]		*[[Glutathione S-transferase\|Glutathione S-transferase]]
		+	__TOC__
		+	</StructureSection>
	[[Category: Glutathione transferase]]		[[Category: Glutathione transferase]]
	[[Category: Homo sapiens]]		[[Category: Homo sapiens]]

OCA: Protected "1yj6" [edit=sysop:move=sysop]

OCA — Sat, 05 Jan 2013 17:28:26 GMT

Protected "1yj6" [edit=sysop:move=sysop]

←Older revision

Revision as of 17:28, 5 January 2013

OCA at 17:28, 5 January 2013

OCA — Sat, 05 Jan 2013 17:28:21 GMT

←Older revision		Revision as of 17:28, 5 January 2013
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-	{{Seed}}
	[[Image:1yj6.png\|left\|200px]]		[[Image:1yj6.png\|left\|200px]]

-	<!--
-	The line below this paragraph, containing "STRUCTURE_1yj6", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_1yj6\| PDB=1yj6 \| SCENE= }}		{{STRUCTURE_1yj6\| PDB=1yj6 \| SCENE= }}

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	==About this Structure==		==About this Structure==
-	~~1YJ6~~ is a 3 ~~chains~~ structure ~~of sequences~~ from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YJ6 OCA].	+	[[1yj6]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YJ6 OCA].
		+
		+	==See Also==
		+	*[[Glutathione S-transferase\|Glutathione S-transferase]]
	[[Category: Glutathione transferase]]		[[Category: Glutathione transferase]]
	[[Category: Homo sapiens]]		[[Category: Homo sapiens]]
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	[[Category: Glutathione]]		[[Category: Glutathione]]
	[[Category: Transferase]]		[[Category: Transferase]]
-	[[Category: Zinc]]
-
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 16:46:44 2009''

OCA at 14:46, 17 February 2009

OCA — Tue, 17 Feb 2009 14:46:45 GMT

←Older revision		Revision as of 14:46, 17 February 2009
Line 1:		Line 1:
-	[[Image:1yj6.~~gif~~\|left\|200px]]	+	{{Seed}}
		+	[[Image:1yj6.png\|left\|200px]]

	<!--		<!--
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	{{STRUCTURE_1yj6\| PDB=1yj6 \| SCENE= }}		{{STRUCTURE_1yj6\| PDB=1yj6 \| SCENE= }}

-	~~'''~~crystal structure of human glutathione S-transferase M1A-1A complexed with glutathionyl-zinc-trihydroxide~~'''~~	+	===crystal structure of human glutathione S-transferase M1A-1A complexed with glutathionyl-zinc-trihydroxide===


	==About this Structure==		==About this Structure==
-	1YJ6 is a ~~[[Single protein]]~~ structure of ~~sequence~~ from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YJ6 OCA].	+	1YJ6 is a 3 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YJ6 OCA].
	[[Category: Glutathione transferase]]		[[Category: Glutathione transferase]]
	[[Category: Homo sapiens]]		[[Category: Homo sapiens]]
-	[[Category: Single protein]]
	[[Category: Almo, S C.]]		[[Category: Almo, S C.]]
	[[Category: Listowsky, I.]]		[[Category: Listowsky, I.]]
Line 30:		Line 30:
	[[Category: Transferase]]		[[Category: Transferase]]
	[[Category: Zinc]]		[[Category: Zinc]]
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on ~~Sat May 3~~ 16:23:~~09 2008~~''	+
		+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 16:46:44 2009''