1yjx - Revision history

OCA at 08:11, 25 October 2023

OCA — Wed, 25 Oct 2023 08:11:09 GMT

←Older revision		Revision as of 08:11, 25 October 2023
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	<StructureSection load='1yjx' size='340' side='right'caption='[[1yjx]], [[Resolution\|resolution]] 2.80Å' scene=''>		<StructureSection load='1yjx' size='340' side='right'caption='[[1yjx]], [[Resolution\|resolution]] 2.80Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1yjx]] is a 12 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Human Human~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YJX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1YJX FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1yjx]] is a 12 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YJX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1YJX FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=CIT:CITRIC+ACID'>CIT</scene>~~, ~~<scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.8Å</td></tr>
-	<tr id='~~related~~'><td class="sblockLbl"><b>[[~~Related_structure~~\|~~Related~~:]]</b></td><td class="sblockDat"><~~div style~~='~~overflow~~: ~~auto; max-height~~: ~~3em;~~'>~~[[1yfk\|1yfk]]~~</~~div~~></td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CIT:CITRIC+ACID'>CIT</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1yjx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1yjx OCA], [https://pdbe.org/1yjx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1yjx RCSB], [https://www.ebi.ac.uk/pdbsum/1yjx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1yjx ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1yjx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1yjx OCA], [https://pdbe.org/1yjx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1yjx RCSB], [https://www.ebi.ac.uk/pdbsum/1yjx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1yjx ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[https://www.uniprot.org/uniprot/PGAM1_HUMAN PGAM1_HUMAN]] Interconversion of 3- and 2-phosphoglycerate with 2,3-bisphosphoglycerate as the primer of the reaction. Can also catalyze the reaction of EC 5.4.2.4 (synthase) and EC 3.1.3.13 (phosphatase), but with a reduced activity.	+	[https://www.uniprot.org/uniprot/PGAM1_HUMAN PGAM1_HUMAN] Interconversion of 3- and 2-phosphoglycerate with 2,3-bisphosphoglycerate as the primer of the reaction. Can also catalyze the reaction of EC 5.4.2.4 (synthase) and EC 3.1.3.13 (phosphatase), but with a reduced activity.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Human~~]]	+	[[Category: Homo sapiens]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Gong, W]]	+	[[Category: Gong W]]
-	[[Category: Liu, L]]	+	[[Category: Liu L]]
-	[[Category: Wang, Y]]	+	[[Category: Wang Y]]
-	[[Category: Wei, Z]]	+	[[Category: Wei Z]]
-	~~[[Category: Alpha/beta]]~~	+
-	~~[[Category: Hydrolase]]~~	+
-	~~[[Category: Isomerase~~]]	+

OCA at 16:29, 3 November 2021

OCA — Wed, 03 Nov 2021 16:29:07 GMT

←Older revision		Revision as of 16:29, 3 November 2021
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	<StructureSection load='1yjx' size='340' side='right'caption='[[1yjx]], [[Resolution\|resolution]] 2.80Å' scene=''>		<StructureSection load='1yjx' size='340' side='right'caption='[[1yjx]], [[Resolution\|resolution]] 2.80Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1yjx]] is a 12 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YJX OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1YJX FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1yjx]] is a 12 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YJX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1YJX FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CIT:CITRIC+ACID'>CIT</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CIT:CITRIC+ACID'>CIT</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1yfk\|1yfk]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1yfk\|1yfk]]</div></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1yjx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1yjx OCA], [~~http~~://pdbe.org/1yjx PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=1yjx RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/1yjx PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=1yjx ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1yjx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1yjx OCA], [https://pdbe.org/1yjx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1yjx RCSB], [https://www.ebi.ac.uk/pdbsum/1yjx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1yjx ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[~~http~~://www.uniprot.org/uniprot/PGAM1_HUMAN PGAM1_HUMAN]] Interconversion of 3- and 2-phosphoglycerate with 2,3-bisphosphoglycerate as the primer of the reaction. Can also catalyze the reaction of EC 5.4.2.4 (synthase) and EC 3.1.3.13 (phosphatase), but with a reduced activity.	+	[[https://www.uniprot.org/uniprot/PGAM1_HUMAN PGAM1_HUMAN]] Interconversion of 3- and 2-phosphoglycerate with 2,3-bisphosphoglycerate as the primer of the reaction. Can also catalyze the reaction of EC 5.4.2.4 (synthase) and EC 3.1.3.13 (phosphatase), but with a reduced activity.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]

OCA at 16:33, 29 January 2020

OCA — Wed, 29 Jan 2020 16:33:49 GMT

←Older revision		Revision as of 16:33, 29 January 2020
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	==Crystal structure of human B type phosphoglycerate mutase==		==Crystal structure of human B type phosphoglycerate mutase==
-	<StructureSection load='1yjx' size='340' side='right' caption='[[1yjx]], [[Resolution\|resolution]] 2.80Å' scene=''>	+	<StructureSection load='1yjx' size='340' side='right'caption='[[1yjx]], [[Resolution\|resolution]] 2.80Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1yjx]] is a 12 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YJX OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1YJX FirstGlance]. <br>		<table><tr><td colspan='2'>[[1yjx]] is a 12 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YJX OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1YJX FirstGlance]. <br>
Line 31:		Line 31:

	==See Also==		==See Also==
-	*[[Phosphoglycerate ~~Mutase~~\|Phosphoglycerate ~~Mutase~~]]	+	*[[Phosphoglycerate mutase 3D structures\|Phosphoglycerate mutase 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
Line 37:		Line 37:
	</StructureSection>		</StructureSection>
	[[Category: Human]]		[[Category: Human]]
		+	[[Category: Large Structures]]
	[[Category: Gong, W]]		[[Category: Gong, W]]
	[[Category: Liu, L]]		[[Category: Liu, L]]

OCA at 06:21, 25 April 2018

OCA — Wed, 25 Apr 2018 06:21:57 GMT

←Older revision		Revision as of 06:21, 25 April 2018
Line 1:		Line 1:
		+
	==Crystal structure of human B type phosphoglycerate mutase==		==Crystal structure of human B type phosphoglycerate mutase==
	<StructureSection load='1yjx' size='340' side='right' caption='[[1yjx]], [[Resolution\|resolution]] 2.80Å' scene=''>		<StructureSection load='1yjx' size='340' side='right' caption='[[1yjx]], [[Resolution\|resolution]] 2.80Å' scene=''>
Line 5:		Line 6:
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CIT:CITRIC+ACID'>CIT</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CIT:CITRIC+ACID'>CIT</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1yfk\|1yfk]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1yfk\|1yfk]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1yjx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1yjx OCA], [http://pdbe.org/1yjx PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1yjx RCSB], [http://www.ebi.ac.uk/pdbsum/1yjx PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1yjx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1yjx OCA], [http://pdbe.org/1yjx PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1yjx RCSB], [http://www.ebi.ac.uk/pdbsum/1yjx PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1yjx ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 13:		Line 14:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/yj/1yjx_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/yj/1yjx_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>

OCA at 03:45, 9 February 2016

OCA — Tue, 09 Feb 2016 03:45:46 GMT

←Older revision		Revision as of 03:45, 9 February 2016
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	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1yjx ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 18:18, 10 September 2015

OCA — Thu, 10 Sep 2015 18:18:39 GMT

←Older revision		Revision as of 18:18, 10 September 2015
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	<StructureSection load='1yjx' size='340' side='right' caption='[[1yjx]], [[Resolution\|resolution]] 2.80Å' scene=''>		<StructureSection load='1yjx' size='340' side='right' caption='[[1yjx]], [[Resolution\|resolution]] 2.80Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1yjx]] is a 12 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Homo_sapiens Homo sapiens~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YJX OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1YJX FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1yjx]] is a 12 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YJX OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1YJX FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CIT:CITRIC+ACID'>CIT</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CIT:CITRIC+ACID'>CIT</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1yfk\|1yfk]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1yfk\|1yfk]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1yjx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1yjx OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1yjx RCSB], [http://www.ebi.ac.uk/pdbsum/1yjx PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1yjx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1yjx OCA], [http://pdbe.org/1yjx PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1yjx RCSB], [http://www.ebi.ac.uk/pdbsum/1yjx PDBsum]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 27:		Line 27:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 1yjx" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
Line 34:		Line 35:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Homo sapiens~~]]	+	[[Category: Human]]
	[[Category: Gong, W]]		[[Category: Gong, W]]
	[[Category: Liu, L]]		[[Category: Liu, L]]

OCA at 04:11, 25 December 2014

OCA — Thu, 25 Dec 2014 04:11:45 GMT

←Older revision		Revision as of 04:11, 25 December 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1yjx]] is a 12 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YJX OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1YJX FirstGlance]. <br>		<table><tr><td colspan='2'>[[1yjx]] is a 12 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YJX OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1YJX FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CIT:CITRIC+ACID'>CIT</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene><br>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CIT:CITRIC+ACID'>CIT</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr>
-	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1yfk\|1yfk]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1yfk\|1yfk]]</td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1yjx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1yjx OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1yjx RCSB], [http://www.ebi.ac.uk/pdbsum/1yjx PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1yjx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1yjx OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1yjx RCSB], [http://www.ebi.ac.uk/pdbsum/1yjx PDBsum]</span></td></tr>
-	<table>	+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/PGAM1_HUMAN PGAM1_HUMAN]] Interconversion of 3- and 2-phosphoglycerate with 2,3-bisphosphoglycerate as the primer of the reaction. Can also catalyze the reaction of EC 5.4.2.4 (synthase) and EC 3.1.3.13 (phosphatase), but with a reduced activity.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 33:		Line 35:
	</StructureSection>		</StructureSection>
	[[Category: Homo sapiens]]		[[Category: Homo sapiens]]
-	[[Category: Gong, W.]]	+	[[Category: Gong, W]]
-	[[Category: Liu, L.]]	+	[[Category: Liu, L]]
-	[[Category: Wang, Y.]]	+	[[Category: Wang, Y]]
-	[[Category: Wei, Z.]]	+	[[Category: Wei, Z]]
	[[Category: Alpha/beta]]		[[Category: Alpha/beta]]
	[[Category: Hydrolase]]		[[Category: Hydrolase]]
	[[Category: Isomerase]]		[[Category: Isomerase]]

OCA at 21:29, 28 September 2014

OCA — Sun, 28 Sep 2014 21:29:05 GMT

←Older revision		Revision as of 21:29, 28 September 2014
Line 1:		Line 1:
-	[[~~Image:~~1yjx.~~png~~\|~~left~~\|200px]]	+	==Crystal structure of human B type phosphoglycerate mutase==
		+	<StructureSection load='1yjx' size='340' side='right' caption='[[1yjx]], [[Resolution\|resolution]] 2.80Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[1yjx]] is a 12 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YJX OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1YJX FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CIT:CITRIC+ACID'>CIT</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene><br>
		+	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1yfk\|1yfk]]</td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1yjx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1yjx OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1yjx RCSB], [http://www.ebi.ac.uk/pdbsum/1yjx PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/yj/1yjx_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	The B-type cofactor-dependent phosphoglycerate mutase (dPGM-B) catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate in glycolysis and gluconeogenesis pathways using 2,3-bisphosphoglycerate as the cofactor. The crystal structures of human dPGM-B bound with citrate were determined in two crystal forms. These structures reveal a dimerization mode conserved in both of dPGM and BPGM (bisphosphoglycerate mutase), based on which a dPGM/BPGM heterodimer structure is proposed. Structural comparison supports that the conformational changes of residues 13-21 and 98-117 determine PGM/BPGM activity differences. The citrate-binding mode suggests a substrate-binding model, consistent with the structure of Escherichia coli dPGM/vanadate complex. A chloride ion was found in the center of the dimer, providing explanation for the contribution of chloride ion to dPGM activities. Based on the structural information, the possible reasons for the deficient human dPGM mutations found in some patients are also discussed.

-	~~{{STRUCTURE_1yjx\| PDB=1yjx \| SCENE= }}~~	+	Crystal structure of human B-type phosphoglycerate mutase bound with citrate.,Wang Y, Wei Z, Liu L, Cheng Z, Lin Y, Ji F, Gong W Biochem Biophys Res Commun. 2005 Jun 17;331(4):1207-15. PMID:15883004<ref>PMID:15883004</ref>

-	~~===Crystal structure~~ of ~~human B type phosphoglycerate mutase===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_15883004}}~~	+
-		+
-	~~==About this Structure==~~	+
-	~~[[1yjx]] is a 12 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Homo_sapiens Homo sapiens]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=1YJX OCA].~~	+

	==See Also==		==See Also==
	*[[Phosphoglycerate Mutase\|Phosphoglycerate Mutase]]		*[[Phosphoglycerate Mutase\|Phosphoglycerate Mutase]]
-		+	== References ==
-	==~~Reference~~==	+	<references/>
-	<~~ref group="xtra">PMID:015883004<~~/~~ref~~><~~references group="xtra"~~/>	+	__TOC__
		+	</StructureSection>
	[[Category: Homo sapiens]]		[[Category: Homo sapiens]]
	[[Category: Gong, W.]]		[[Category: Gong, W.]]

OCA at 12:32, 20 October 2012

OCA — Sat, 20 Oct 2012 12:32:01 GMT

←Older revision		Revision as of 12:32, 20 October 2012
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	==About this Structure==		==About this Structure==
-	[[1yjx]] is a 12 chain structure ~~of [[Phosphoglycerate Mutase]]~~ with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YJX OCA].	+	[[1yjx]] is a 12 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YJX OCA].

	==See Also==		==See Also==

OCA: Protected "1yjx" [edit=sysop:move=sysop]

OCA — Thu, 26 Jul 2012 09:01:24 GMT

Protected "1yjx" [edit=sysop:move=sysop]

←Older revision

Revision as of 09:01, 26 July 2012