1yn3 - Revision history

OCA at 06:59, 23 August 2023

OCA — Wed, 23 Aug 2023 06:59:02 GMT

←Older revision		Revision as of 06:59, 23 August 2023
Line 3:		Line 3:
	<StructureSection load='1yn3' size='340' side='right'caption='[[1yn3]], [[Resolution\|resolution]] 1.35Å' scene=''>		<StructureSection load='1yn3' size='340' side='right'caption='[[1yn3]], [[Resolution\|resolution]] 1.35Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1yn3]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/~~"micrococcus_aureus"_(rosenbach_1884)_zopf_1885 "micrococcus~~ aureus~~" (rosenbach 1884) zopf 1885~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YN3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1YN3 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1yn3]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YN3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1YN3 FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1yn3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1yn3 OCA], [https://pdbe.org/1yn3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1yn3 RCSB], [https://www.ebi.ac.uk/pdbsum/1yn3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1yn3 ProSAT]</span></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.35Å</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1yn3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1yn3 OCA], [https://pdbe.org/1yn3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1yn3 RCSB], [https://www.ebi.ac.uk/pdbsum/1yn3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1yn3 ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/MAP_STAAM MAP_STAAM]
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
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	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Geisbrecht~~, B V~~]]	+	[[Category: Staphylococcus aureus]]
-	[[Category: Hamaoka~~, B Y~~]]	+	[[Category: Geisbrecht BV]]
-	[[Category: Leahy~~, D J~~]]	+	[[Category: Hamaoka BY]]
-	[[Category: Perman, B]]	+	[[Category: Leahy DJ]]
-	[[Category: Zemla, A]]	+	[[Category: Perman B]]
-	~~[[Category: Extracellular-adherence protein]]~~	+	[[Category: Zemla A]]
-	~~[[Category: Protein binding]]~~	+
-	~~[[Category: Staphylococcus]]~~	+
-	~~[[Category: Toxin]]~~	+
-	~~[[Category: Virulence-factor~~]]	+

OCA at 16:54, 20 October 2021

OCA — Wed, 20 Oct 2021 16:54:25 GMT

←Older revision		Revision as of 16:54, 20 October 2021
Line 3:		Line 3:
	<StructureSection load='1yn3' size='340' side='right'caption='[[1yn3]], [[Resolution\|resolution]] 1.35Å' scene=''>		<StructureSection load='1yn3' size='340' side='right'caption='[[1yn3]], [[Resolution\|resolution]] 1.35Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1yn3]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/"micrococcus_aureus"_(rosenbach_1884)_zopf_1885 "micrococcus aureus" (rosenbach 1884) zopf 1885]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YN3 OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1YN3 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1yn3]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/"micrococcus_aureus"_(rosenbach_1884)_zopf_1885 "micrococcus aureus" (rosenbach 1884) zopf 1885]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YN3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1YN3 FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1yn3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1yn3 OCA], [~~http~~://pdbe.org/1yn3 PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=1yn3 RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/1yn3 PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=1yn3 ProSAT]</span></td></tr>	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1yn3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1yn3 OCA], [https://pdbe.org/1yn3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1yn3 RCSB], [https://www.ebi.ac.uk/pdbsum/1yn3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1yn3 ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==

OCA at 17:00, 29 January 2020

OCA — Wed, 29 Jan 2020 17:00:30 GMT

←Older revision		Revision as of 17:00, 29 January 2020
Line 1:		Line 1:

	==Crystal Structures of EAP Domains from Staphylococcus aureus Reveal an Unexpected Homology to Bacterial Superantigens==		==Crystal Structures of EAP Domains from Staphylococcus aureus Reveal an Unexpected Homology to Bacterial Superantigens==
-	<StructureSection load='1yn3' size='340' side='right' caption='[[1yn3]], [[Resolution\|resolution]] 1.35Å' scene=''>	+	<StructureSection load='1yn3' size='340' side='right'caption='[[1yn3]], [[Resolution\|resolution]] 1.35Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1yn3]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/"micrococcus_aureus"_(rosenbach_1884)_zopf_1885 "micrococcus aureus" (rosenbach 1884) zopf 1885]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YN3 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1YN3 FirstGlance]. <br>		<table><tr><td colspan='2'>[[1yn3]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/"micrococcus_aureus"_(rosenbach_1884)_zopf_1885 "micrococcus aureus" (rosenbach 1884) zopf 1885]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YN3 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1YN3 FirstGlance]. <br>
Line 29:		Line 29:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Large Structures]]
	[[Category: Geisbrecht, B V]]		[[Category: Geisbrecht, B V]]
	[[Category: Hamaoka, B Y]]		[[Category: Hamaoka, B Y]]

OCA at 06:45, 25 April 2018

OCA — Wed, 25 Apr 2018 06:45:37 GMT

←Older revision		Revision as of 06:45, 25 April 2018
Line 1:		Line 1:
		+
	==Crystal Structures of EAP Domains from Staphylococcus aureus Reveal an Unexpected Homology to Bacterial Superantigens==		==Crystal Structures of EAP Domains from Staphylococcus aureus Reveal an Unexpected Homology to Bacterial Superantigens==
	<StructureSection load='1yn3' size='340' side='right' caption='[[1yn3]], [[Resolution\|resolution]] 1.35Å' scene=''>		<StructureSection load='1yn3' size='340' side='right' caption='[[1yn3]], [[Resolution\|resolution]] 1.35Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1yn3]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/"micrococcus_aureus"_(rosenbach_1884)_zopf_1885 "micrococcus aureus" (rosenbach 1884) zopf 1885]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YN3 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1YN3 FirstGlance]. <br>		<table><tr><td colspan='2'>[[1yn3]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/"micrococcus_aureus"_(rosenbach_1884)_zopf_1885 "micrococcus aureus" (rosenbach 1884) zopf 1885]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YN3 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1YN3 FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1yn3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1yn3 OCA], [http://pdbe.org/1yn3 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1yn3 RCSB], [http://www.ebi.ac.uk/pdbsum/1yn3 PDBsum]</span></td></tr>	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1yn3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1yn3 OCA], [http://pdbe.org/1yn3 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1yn3 RCSB], [http://www.ebi.ac.uk/pdbsum/1yn3 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1yn3 ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 9:		Line 10:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/yn/1yn3_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/yn/1yn3_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>

OCA at 06:07, 8 February 2016

OCA — Mon, 08 Feb 2016 06:07:40 GMT

←Older revision		Revision as of 06:07, 8 February 2016
Line 13:		Line 13:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1yn3 ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 08:38, 10 September 2015

OCA — Thu, 10 Sep 2015 08:38:24 GMT

←Older revision		Revision as of 08:38, 10 September 2015
Line 2:		Line 2:
	<StructureSection load='1yn3' size='340' side='right' caption='[[1yn3]], [[Resolution\|resolution]] 1.35Å' scene=''>		<StructureSection load='1yn3' size='340' side='right' caption='[[1yn3]], [[Resolution\|resolution]] 1.35Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1yn3]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Staphylococcus_aureus Staphylococcus~~ aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YN3 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1YN3 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1yn3]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/"micrococcus_aureus"_(rosenbach_1884)_zopf_1885 "micrococcus aureus" (rosenbach 1884) zopf 1885]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YN3 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1YN3 FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1yn3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1yn3 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1yn3 RCSB], [http://www.ebi.ac.uk/pdbsum/1yn3 PDBsum]</span></td></tr>	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1yn3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1yn3 OCA], [http://pdbe.org/1yn3 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1yn3 RCSB], [http://www.ebi.ac.uk/pdbsum/1yn3 PDBsum]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
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	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 1yn3" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Staphylococcus aureus]]
	[[Category: Geisbrecht, B V]]		[[Category: Geisbrecht, B V]]
	[[Category: Hamaoka, B Y]]		[[Category: Hamaoka, B Y]]

OCA at 09:23, 8 January 2015

OCA — Thu, 08 Jan 2015 09:23:12 GMT

←Older revision		Revision as of 09:23, 8 January 2015
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1yn3]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YN3 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1YN3 FirstGlance]. <br>		<table><tr><td colspan='2'>[[1yn3]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YN3 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1YN3 FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1yn3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1yn3 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1yn3 RCSB], [http://www.ebi.ac.uk/pdbsum/1yn3 PDBsum]</span></td></tr>	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1yn3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1yn3 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1yn3 RCSB], [http://www.ebi.ac.uk/pdbsum/1yn3 PDBsum]</span></td></tr>
-	<table>	+	</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 28:		Line 28:
	</StructureSection>		</StructureSection>
	[[Category: Staphylococcus aureus]]		[[Category: Staphylococcus aureus]]
-	[[Category: Geisbrecht, B V.]]	+	[[Category: Geisbrecht, B V]]
-	[[Category: Hamaoka, B Y.]]	+	[[Category: Hamaoka, B Y]]
-	[[Category: Leahy, D J.]]	+	[[Category: Leahy, D J]]
-	[[Category: Perman, B.]]	+	[[Category: Perman, B]]
-	[[Category: Zemla, A.]]	+	[[Category: Zemla, A]]
	[[Category: Extracellular-adherence protein]]		[[Category: Extracellular-adherence protein]]
	[[Category: Protein binding]]		[[Category: Protein binding]]

OCA at 21:27, 29 September 2014

OCA — Mon, 29 Sep 2014 21:27:59 GMT

←Older revision		Revision as of 21:27, 29 September 2014
Line 1:		Line 1:
-	[[~~Image~~:1yn3.~~png\|left~~\|200px]]	+	==Crystal Structures of EAP Domains from Staphylococcus aureus Reveal an Unexpected Homology to Bacterial Superantigens==
		+	<StructureSection load='1yn3' size='340' side='right' caption='[[1yn3]], [[Resolution\|resolution]] 1.35Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[1yn3]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YN3 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1YN3 FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1yn3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1yn3 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1yn3 RCSB], [http://www.ebi.ac.uk/pdbsum/1yn3 PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/yn/1yn3_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	The Eap (extracellular adherence protein) of Staphylococcus aureus functions as a secreted virulence factor by mediating interactions between the bacterial cell surface and several extracellular host proteins. Eap proteins from different Staphylococcal strains consist of four to six tandem repeats of a structurally uncharacterized domain (EAP domain). We have determined the three-dimensional structures of three different EAP domains to 1.8, 2.2, and 1.35 A resolution, respectively. These structures reveal a core fold that is comprised of an alpha-helix lying diagonally across a five-stranded, mixed beta-sheet. Comparison of EAP domains with known structures reveals an unexpected homology with the C-terminal domain of bacterial superantigens. Examination of the structure of the superantigen SEC2 bound to the beta-chain of a T-cell receptor suggests a possible ligand-binding site within the EAP domain (Fields, B. A., Malchiodi, E. L., Li, H., Ysern, X., Stauffacher, C. V., Schlievert, P. M., Karjalainen, K., and Mariuzza, R. (1996) Nature 384, 188-192). These results provide the first structural characterization of EAP domains, relate EAP domains to a large class of bacterial toxins, and will guide the design of future experiments to analyze EAP domain structure/function relationships.

-	~~{{STRUCTURE_1yn3\| PDB=1yn3 \| SCENE= }}~~	+	The crystal structures of EAP domains from Staphylococcus aureus reveal an unexpected homology to bacterial superantigens.,Geisbrecht BV, Hamaoka BY, Perman B, Zemla A, Leahy DJ J Biol Chem. 2005 Apr 29;280(17):17243-50. Epub 2005 Feb 3. PMID:15691839<ref>PMID:15691839</ref>

-	~~===Crystal Structures~~ of ~~EAP Domains from Staphylococcus aureus Reveal an Unexpected Homology to Bacterial Superantigens===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_15691839}}~~	+	== References ==
-		+	<references/>
-	~~==About this Structure==~~	+	__TOC__
-	~~[[1yn3]] is a 2 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Staphylococcus_aureus Staphylococcus aureus]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=1YN3 OCA].~~	+	</StructureSection>
-		+
-	==~~Reference~~==	+
-	<~~ref group="xtra">PMID:015691839<~~/~~ref~~><~~references group="xtra"~~/>	+
	[[Category: Staphylococcus aureus]]		[[Category: Staphylococcus aureus]]
	[[Category: Geisbrecht, B V.]]		[[Category: Geisbrecht, B V.]]

OCA: Protected "1yn3" [edit=sysop:move=sysop]

OCA — Sat, 05 Jan 2013 17:23:55 GMT

Protected "1yn3" [edit=sysop:move=sysop]

←Older revision

Revision as of 17:23, 5 January 2013

OCA at 17:23, 5 January 2013

OCA — Sat, 05 Jan 2013 17:23:52 GMT

←Older revision		Revision as of 17:23, 5 January 2013
Line 1:		Line 1:
-	{{Seed}}
	[[Image:1yn3.png\|left\|200px]]		[[Image:1yn3.png\|left\|200px]]

-	<!--
-	The line below this paragraph, containing "STRUCTURE_1yn3", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_1yn3\| PDB=1yn3 \| SCENE= }}		{{STRUCTURE_1yn3\| PDB=1yn3 \| SCENE= }}

	===Crystal Structures of EAP Domains from Staphylococcus aureus Reveal an Unexpected Homology to Bacterial Superantigens===		===Crystal Structures of EAP Domains from Staphylococcus aureus Reveal an Unexpected Homology to Bacterial Superantigens===

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	{{ABSTRACT_PUBMED_15691839}}		{{ABSTRACT_PUBMED_15691839}}

	==About this Structure==		==About this Structure==
-	~~1YN3~~ is a 2 ~~chains~~ structure ~~of sequences~~ from [http://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YN3 OCA].	+	[[1yn3]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YN3 OCA].

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~15691839~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:015691839</ref><references group="xtra"/>
	[[Category: Staphylococcus aureus]]		[[Category: Staphylococcus aureus]]
	[[Category: Geisbrecht, B V.]]		[[Category: Geisbrecht, B V.]]
Line 31:		Line 19:
	[[Category: Zemla, A.]]		[[Category: Zemla, A.]]
	[[Category: Extracellular-adherence protein]]		[[Category: Extracellular-adherence protein]]
		+	[[Category: Protein binding]]
	[[Category: Staphylococcus]]		[[Category: Staphylococcus]]
	[[Category: Toxin]]		[[Category: Toxin]]
	[[Category: Virulence-factor]]		[[Category: Virulence-factor]]
-
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 19:41:17 2009''