1ypy - Revision history

OCA at 08:05, 15 May 2024

OCA — Wed, 15 May 2024 08:05:15 GMT

←Older revision		Revision as of 08:05, 15 May 2024
Line 3:		Line 3:
	<StructureSection load='1ypy' size='340' side='right'caption='[[1ypy]], [[Resolution\|resolution]] 1.51Å' scene=''>		<StructureSection load='1ypy' size='340' side='right'caption='[[1ypy]], [[Resolution\|resolution]] 1.51Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1ypy]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Vaccinia_virus Vaccinia virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YPY OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=1YPY FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1ypy]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Vaccinia_virus Vaccinia virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YPY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1YPY FirstGlance]. <br>
-	</td></tr><tr id='~~gene~~'><td class="sblockLbl"><b>[[~~Gene~~\|~~Gene~~:]]</b></td><td class="sblockDat">~~L1 (~~[~~http://www~~.~~ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info~~&~~srchmode=5&id=10245 Vaccinia virus])~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.51Å</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=1ypy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ypy OCA], [~~http~~://pdbe.org/1ypy PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=1ypy RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/1ypy PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=1ypy ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ypy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ypy OCA], [https://pdbe.org/1ypy PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ypy RCSB], [https://www.ebi.ac.uk/pdbsum/1ypy PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ypy ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[~~[http~~://www.uniprot.org/uniprot/L1_VACCW L1_VACCW]] Envelope protein which probably plays a role in virus entry into the host cell. Is probably involved in the virus attachment to the host cell surface and associates with the entry/fusion complex (EFC). Needed for fusion and penetration of the virus core into host cell.<ref>PMID:8083978</ref> <ref>PMID:18596103</ref> <ref>PMID:19162289</ref>	+	[https://www.uniprot.org/uniprot/L1_VACCW L1_VACCW] Envelope protein which probably plays a role in virus entry into the host cell. Is probably involved in the virus attachment to the host cell surface and associates with the entry/fusion complex (EFC). Needed for fusion and penetration of the virus core into host cell.<ref>PMID:8083978</ref> <ref>PMID:18596103</ref> <ref>PMID:19162289</ref>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 34:		Line 34:
	[[Category: Large Structures]]		[[Category: Large Structures]]
	[[Category: Vaccinia virus]]		[[Category: Vaccinia virus]]
-	[[Category: Allison~~, T J~~]]	+	[[Category: Allison TJ]]
-	[[Category: Fogg, C]]	+	[[Category: Fogg C]]
-	[[Category: Garboczi~~, D N~~]]	+	[[Category: Garboczi DN]]
-	[[Category: Garman~~, S C~~]]	+	[[Category: Garman SC]]
-	[[Category: Moss, B]]	+	[[Category: Moss B]]
-	[[Category: Su~~, H P]]~~	+	[[Category: Su HP]]
-	~~[[Category: L1]]~~	+
-	~~[[Category: Orthopox]]~~	+
-	~~[[Category: Smallpox]]~~	+
-	~~[[Category: Variola virus]]~~	+
-	~~[[Category: Viral protein~~]]	+

OCA at 08:50, 20 January 2021

OCA — Wed, 20 Jan 2021 08:50:11 GMT

←Older revision		Revision as of 08:50, 20 January 2021
Line 1:		Line 1:

	==Crystal Structure of Vaccinia Virus L1 protein==		==Crystal Structure of Vaccinia Virus L1 protein==
-	<StructureSection load='1ypy' size='340' side='right' caption='[[1ypy]], [[Resolution\|resolution]] 1.51Å' scene=''>	+	<StructureSection load='1ypy' size='340' side='right'caption='[[1ypy]], [[Resolution\|resolution]] 1.51Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1ypy]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Vaccinia_virus Vaccinia virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YPY OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1YPY FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1ypy]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Vaccinia_virus Vaccinia virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YPY OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=1YPY FirstGlance]. <br>
	</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">L1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10245 Vaccinia virus])</td></tr>		</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">L1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10245 Vaccinia virus])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1ypy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ypy OCA], [http://pdbe.org/1ypy PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1ypy RCSB], [http://www.ebi.ac.uk/pdbsum/1ypy PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1ypy ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=1ypy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ypy OCA], [http://pdbe.org/1ypy PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1ypy RCSB], [http://www.ebi.ac.uk/pdbsum/1ypy PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1ypy ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 13:		Line 13:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/yp/1ypy_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/yp/1ypy_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
Line 32:		Line 32:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Large Structures]]
	[[Category: Vaccinia virus]]		[[Category: Vaccinia virus]]
	[[Category: Allison, T J]]		[[Category: Allison, T J]]

OCA at 10:16, 12 October 2017

OCA — Thu, 12 Oct 2017 10:16:49 GMT

←Older revision		Revision as of 10:16, 12 October 2017
Line 1:		Line 1:
		+
	==Crystal Structure of Vaccinia Virus L1 protein==		==Crystal Structure of Vaccinia Virus L1 protein==
	<StructureSection load='1ypy' size='340' side='right' caption='[[1ypy]], [[Resolution\|resolution]] 1.51Å' scene=''>		<StructureSection load='1ypy' size='340' side='right' caption='[[1ypy]], [[Resolution\|resolution]] 1.51Å' scene=''>
Line 4:		Line 5:
	<table><tr><td colspan='2'>[[1ypy]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Vaccinia_virus Vaccinia virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YPY OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1YPY FirstGlance]. <br>		<table><tr><td colspan='2'>[[1ypy]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Vaccinia_virus Vaccinia virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YPY OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1YPY FirstGlance]. <br>
	</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">L1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10245 Vaccinia virus])</td></tr>		</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">L1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10245 Vaccinia virus])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ypy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ypy OCA], [http://pdbe.org/1ypy PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1ypy RCSB], [http://www.ebi.ac.uk/pdbsum/1ypy PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ypy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ypy OCA], [http://pdbe.org/1ypy PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1ypy RCSB], [http://www.ebi.ac.uk/pdbsum/1ypy PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1ypy ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==

OCA at 04:05, 10 February 2016

OCA — Wed, 10 Feb 2016 04:05:35 GMT

←Older revision		Revision as of 04:05, 10 February 2016
Line 16:		Line 16:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1ypy ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 05:12, 11 September 2015

OCA — Fri, 11 Sep 2015 05:12:48 GMT

←Older revision		Revision as of 05:12, 11 September 2015
Line 4:		Line 4:
	<table><tr><td colspan='2'>[[1ypy]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Vaccinia_virus Vaccinia virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YPY OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1YPY FirstGlance]. <br>		<table><tr><td colspan='2'>[[1ypy]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Vaccinia_virus Vaccinia virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YPY OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1YPY FirstGlance]. <br>
	</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">L1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10245 Vaccinia virus])</td></tr>		</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">L1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10245 Vaccinia virus])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ypy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ypy OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1ypy RCSB], [http://www.ebi.ac.uk/pdbsum/1ypy PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ypy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ypy OCA], [http://pdbe.org/1ypy PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1ypy RCSB], [http://www.ebi.ac.uk/pdbsum/1ypy PDBsum]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[http://www.uniprot.org/uniprot/~~VM25_VACCV VM25_VACCV~~]] Envelope protein which probably plays a role in virus entry into the host cell. Is probably involved in the virus attachment to the host cell surface and associates with the entry/fusion complex (EFC). Needed for fusion and penetration of the virus core into host cell.<ref>PMID:8083978</ref> <ref>PMID:18596103</ref> <ref>PMID:19162289</ref>	+	[[http://www.uniprot.org/uniprot/L1_VACCW L1_VACCW]] Envelope protein which probably plays a role in virus entry into the host cell. Is probably involved in the virus attachment to the host cell surface and associates with the entry/fusion complex (EFC). Needed for fusion and penetration of the virus core into host cell.<ref>PMID:8083978</ref> <ref>PMID:18596103</ref> <ref>PMID:19162289</ref>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 26:		Line 26:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 1ypy" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>

OCA at 11:40, 25 December 2014

OCA — Thu, 25 Dec 2014 11:40:40 GMT

←Older revision		Revision as of 11:40, 25 December 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1ypy]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Vaccinia_virus Vaccinia virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YPY OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1YPY FirstGlance]. <br>		<table><tr><td colspan='2'>[[1ypy]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Vaccinia_virus Vaccinia virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YPY OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1YPY FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">L1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10245 Vaccinia virus])</td></tr>	+	</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">L1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10245 Vaccinia virus])</td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ypy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ypy OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1ypy RCSB], [http://www.ebi.ac.uk/pdbsum/1ypy PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ypy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ypy OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1ypy RCSB], [http://www.ebi.ac.uk/pdbsum/1ypy PDBsum]</span></td></tr>
-	<table>	+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/VM25_VACCV VM25_VACCV]] Envelope protein which probably plays a role in virus entry into the host cell. Is probably involved in the virus attachment to the host cell surface and associates with the entry/fusion complex (EFC). Needed for fusion and penetration of the virus core into host cell.<ref>PMID:8083978</ref> <ref>PMID:18596103</ref> <ref>PMID:19162289</ref>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 29:		Line 31:
	</StructureSection>		</StructureSection>
	[[Category: Vaccinia virus]]		[[Category: Vaccinia virus]]
-	[[Category: Allison, T J.]]	+	[[Category: Allison, T J]]
-	[[Category: Fogg, C.]]	+	[[Category: Fogg, C]]
-	[[Category: Garboczi, D N.]]	+	[[Category: Garboczi, D N]]
-	[[Category: Garman, S C.]]	+	[[Category: Garman, S C]]
-	[[Category: Moss, B.]]	+	[[Category: Moss, B]]
-	[[Category: Su, H P.]]	+	[[Category: Su, H P]]
	[[Category: L1]]		[[Category: L1]]
	[[Category: Orthopox]]		[[Category: Orthopox]]
	[[Category: Smallpox]]		[[Category: Smallpox]]
-	[[Category: Vaccinia virus]]
	[[Category: Variola virus]]		[[Category: Variola virus]]
	[[Category: Viral protein]]		[[Category: Viral protein]]

OCA at 18:51, 29 September 2014

OCA — Mon, 29 Sep 2014 18:51:08 GMT

←Older revision		Revision as of 18:51, 29 September 2014
Line 1:		Line 1:
-	[[~~Image~~:1ypy.~~png\|left~~\|200px]]	+	==Crystal Structure of Vaccinia Virus L1 protein==
		+	<StructureSection load='1ypy' size='340' side='right' caption='[[1ypy]], [[Resolution\|resolution]] 1.51Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[1ypy]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Vaccinia_virus Vaccinia virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YPY OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1YPY FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">L1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10245 Vaccinia virus])</td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ypy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ypy OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1ypy RCSB], [http://www.ebi.ac.uk/pdbsum/1ypy PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/yp/1ypy_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Although eradicated from nature more than two decades ago, the threat of smallpox has reemerged because of concerns over its use as a biological weapon. We present the structure of the poxvirus L1 protein, a molecule that is conserved throughout the poxvirus family and is nearly identical in vaccinia virus and in variola virus, which causes smallpox. L1 is a myristoylated envelope protein that is a potent target for neutralizing antibodies and an important component of current experimental vaccines. The L1 structure reveals a hydrophobic cavity located adjacent to its N terminus. The cavity would be capable of shielding the myristate moiety, which is essential for virion assembly. The structure of L1 is a step in the elucidation of molecular mechanisms common to all poxviruses that may stimulate the design of safer vaccines and new antipoxvirus drugs.

-	~~{{STRUCTURE_1ypy\| PDB=1ypy \| SCENE= }}~~	+	The 1.51-Angstrom structure of the poxvirus L1 protein, a target of potent neutralizing antibodies.,Su HP, Garman SC, Allison TJ, Fogg C, Moss B, Garboczi DN Proc Natl Acad Sci U S A. 2005 Mar 22;102(12):4240-5. Epub 2005 Mar 10. PMID:15761054<ref>PMID:15761054</ref>

-	~~===Crystal Structure~~ of ~~Vaccinia Virus L1 protein===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_15761054}}~~	+	== References ==
-		+	<references/>
-	~~==About this Structure==~~	+	__TOC__
-	~~[[1ypy]] is a 2 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Vaccinia_virus Vaccinia virus]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=1YPY OCA].~~	+	</StructureSection>
-		+
-	==~~Reference~~==	+
-	<~~ref group="xtra">PMID:015761054<~~/~~ref~~><~~references group="xtra"~~/>	+
	[[Category: Vaccinia virus]]		[[Category: Vaccinia virus]]
	[[Category: Allison, T J.]]		[[Category: Allison, T J.]]

OCA: Protected "1ypy" [edit=sysop:move=sysop]

OCA — Sat, 05 Jan 2013 17:00:52 GMT

Protected "1ypy" [edit=sysop:move=sysop]

←Older revision

Revision as of 17:00, 5 January 2013

OCA at 17:00, 5 January 2013

OCA — Sat, 05 Jan 2013 17:00:48 GMT

←Older revision		Revision as of 17:00, 5 January 2013
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-	{{Seed}}
	[[Image:1ypy.png\|left\|200px]]		[[Image:1ypy.png\|left\|200px]]

-	<!--
-	The line below this paragraph, containing "STRUCTURE_1ypy", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_1ypy\| PDB=1ypy \| SCENE= }}		{{STRUCTURE_1ypy\| PDB=1ypy \| SCENE= }}

	===Crystal Structure of Vaccinia Virus L1 protein===		===Crystal Structure of Vaccinia Virus L1 protein===

-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_15761054}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where 15761054 is the PubMed ID number.
-	-->
	{{ABSTRACT_PUBMED_15761054}}		{{ABSTRACT_PUBMED_15761054}}

	==About this Structure==		==About this Structure==
-	~~1YPY~~ is a 2 ~~chains~~ structure ~~of sequences~~ from [http://en.wikipedia.org/wiki/Vaccinia_virus Vaccinia virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YPY OCA].	+	[[1ypy]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Vaccinia_virus Vaccinia virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YPY OCA].

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~15761054~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:015761054</ref><references group="xtra"/>
	[[Category: Vaccinia virus]]		[[Category: Vaccinia virus]]
	[[Category: Allison, T J.]]		[[Category: Allison, T J.]]
Line 36:		Line 24:
	[[Category: Vaccinia virus]]		[[Category: Vaccinia virus]]
	[[Category: Variola virus]]		[[Category: Variola virus]]
-		+	[[Category: Viral protein]]
-	~~''Page seeded by~~ [~~http~~:~~//oca.weizmann.ac.il/oca OCA~~ ] ~~on Tue Feb 17 15:17:38 2009''~~	+

OCA at 13:17, 17 February 2009

OCA — Tue, 17 Feb 2009 13:17:39 GMT

←Older revision		Revision as of 13:17, 17 February 2009
Line 20:		Line 20:

	==About this Structure==		==About this Structure==
-	1YPY is a ~~[[Single protein]]~~ structure of ~~sequence~~ from [http://en.wikipedia.org/wiki/Vaccinia_virus Vaccinia virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YPY OCA].	+	1YPY is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Vaccinia_virus Vaccinia virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YPY OCA].

	==Reference==		==Reference==
-	The 1.51-Angstrom structure of the poxvirus L1 protein, a target of potent neutralizing antibodies., Su HP, Garman SC, Allison TJ, Fogg C, Moss B, Garboczi DN, Proc Natl Acad Sci U S A. 2005 Mar 22;102(12):4240-5. Epub 2005 Mar 10. PMID:~~[http:~~//~~www.ncbi.nlm.nih.gov/pubmed/15761054 15761054]~~	+	<ref group="xtra">PMID:15761054</ref><references group="xtra"/>
-	~~[[Category: Single protein]]~~	+
	[[Category: Vaccinia virus]]		[[Category: Vaccinia virus]]
	[[Category: Allison, T J.]]		[[Category: Allison, T J.]]
Line 38:		Line 37:
	[[Category: Variola virus]]		[[Category: Variola virus]]

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on ~~Mon Jul 28 20~~:54:~~08 2008~~''	+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 15:17:38 2009''