1z1v - Revision history

OCA at 09:31, 6 December 2023

OCA — Wed, 06 Dec 2023 09:31:11 GMT

←Older revision		Revision as of 09:31, 6 December 2023
Line 1:		Line 1:

	==NMR structure of the Saccharomyces cerevisiae Ste50 SAM domain==		==NMR structure of the Saccharomyces cerevisiae Ste50 SAM domain==
-	<StructureSection load='1z1v' size='340' side='right'caption='[[1z1v~~]], [[NMR_Ensembles_of_Models \| 1 NMR models~~]]' scene=''>	+	<StructureSection load='1z1v' size='340' side='right'caption='[[1z1v]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1z1v]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Atcc_18824 Atcc 18824~~]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Z1V OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1Z1V FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1z1v]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Z1V OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1Z1V FirstGlance]. <br>
-	</td></tr><tr id='~~related~~'><td class="sblockLbl"><b>[[~~Related_structure~~\|~~Related~~:]]</b></td><td class="sblockDat"~~><div style='overflow: auto; max-height: 3em;'>[[1uqv\|1uqv]]</div></td></tr>~~	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
-	~~<tr~~ id~~='gene'><td class~~="~~sblockLbl~~">~~<b>[[Gene\|Gene:]]</b></td><td class="sblockDat">STE50 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=4932 ATCC 18824])~~</td></tr>	+
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1z1v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1z1v OCA], [https://pdbe.org/1z1v PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1z1v RCSB], [https://www.ebi.ac.uk/pdbsum/1z1v PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1z1v ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1z1v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1z1v OCA], [https://pdbe.org/1z1v PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1z1v RCSB], [https://www.ebi.ac.uk/pdbsum/1z1v PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1z1v ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[https://www.uniprot.org/uniprot/STE50_YEAST STE50_YEAST]] Involved in growth arrest during conjugation. May interact with the G protein alpha subunit.	+	[https://www.uniprot.org/uniprot/STE50_YEAST STE50_YEAST] Involved in growth arrest during conjugation. May interact with the G protein alpha subunit.
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 23:		Line 22:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Atcc 18824]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Donaldson~~, L W~~]]	+	[[Category: Saccharomyces cerevisiae]]
-	[[Category: Kwan~~, J J~~]]	+	[[Category: Donaldson LW]]
-	[[Category: Maini, J]]	+	[[Category: Kwan JJ]]
-	[[Category: Pawson, T]]	+	[[Category: Maini J]]
-	[[Category: Warner, N]]	+	[[Category: Pawson T]]
-	~~[[Category: All helix protein]]~~	+	[[Category: Warner N]]
-	~~[[Category: Cell cycle]]~~	+
-	~~[[Category: Sam domain~~]]	+

OCA at 07:15, 2 March 2022

OCA — Wed, 02 Mar 2022 07:15:34 GMT

←Older revision		Revision as of 07:15, 2 March 2022
Line 3:		Line 3:
	<StructureSection load='1z1v' size='340' side='right'caption='[[1z1v]], [[NMR_Ensembles_of_Models \| 1 NMR models]]' scene=''>		<StructureSection load='1z1v' size='340' side='right'caption='[[1z1v]], [[NMR_Ensembles_of_Models \| 1 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1z1v]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Atcc_18824 Atcc 18824]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Z1V OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=1Z1V FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1z1v]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Atcc_18824 Atcc 18824]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Z1V OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1Z1V FirstGlance]. <br>
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1uqv\|1uqv]]</div></td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1uqv\|1uqv]]</div></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">STE50 ([~~http~~://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=4932 ATCC 18824])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">STE50 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=4932 ATCC 18824])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=1z1v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1z1v OCA], [~~http~~://pdbe.org/1z1v PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=1z1v RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/1z1v PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=1z1v ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1z1v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1z1v OCA], [https://pdbe.org/1z1v PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1z1v RCSB], [https://www.ebi.ac.uk/pdbsum/1z1v PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1z1v ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[~~http~~://www.uniprot.org/uniprot/STE50_YEAST STE50_YEAST]] Involved in growth arrest during conjugation. May interact with the G protein alpha subunit.	+	[[https://www.uniprot.org/uniprot/STE50_YEAST STE50_YEAST]] Involved in growth arrest during conjugation. May interact with the G protein alpha subunit.
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==

OCA at 08:57, 20 January 2021

OCA — Wed, 20 Jan 2021 08:57:04 GMT

←Older revision		Revision as of 08:57, 20 January 2021
Line 1:		Line 1:

	==NMR structure of the Saccharomyces cerevisiae Ste50 SAM domain==		==NMR structure of the Saccharomyces cerevisiae Ste50 SAM domain==
-	<StructureSection load='1z1v' size='340' side='right' caption='[[1z1v]], [[NMR_Ensembles_of_Models \| 1 NMR models]]' scene=''>	+	<StructureSection load='1z1v' size='340' side='right'caption='[[1z1v]], [[NMR_Ensembles_of_Models \| 1 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1z1v]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_18824 Atcc 18824]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Z1V OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1Z1V FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1z1v]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_18824 Atcc 18824]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Z1V OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=1Z1V FirstGlance]. <br>
-	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1uqv\|1uqv]]</td></tr>	+	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1uqv\|1uqv]]</div></td></tr>
	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">STE50 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=4932 ATCC 18824])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">STE50 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=4932 ATCC 18824])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1z1v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1z1v OCA], [http://pdbe.org/1z1v PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1z1v RCSB], [http://www.ebi.ac.uk/pdbsum/1z1v PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1z1v ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=1z1v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1z1v OCA], [http://pdbe.org/1z1v PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1z1v RCSB], [http://www.ebi.ac.uk/pdbsum/1z1v PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1z1v ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 24:		Line 24:
	</StructureSection>		</StructureSection>
	[[Category: Atcc 18824]]		[[Category: Atcc 18824]]
		+	[[Category: Large Structures]]
	[[Category: Donaldson, L W]]		[[Category: Donaldson, L W]]
	[[Category: Kwan, J J]]		[[Category: Kwan, J J]]

OCA at 06:30, 25 April 2018

OCA — Wed, 25 Apr 2018 06:30:17 GMT

←Older revision		Revision as of 06:30, 25 April 2018
Line 1:		Line 1:
		+
	==NMR structure of the Saccharomyces cerevisiae Ste50 SAM domain==		==NMR structure of the Saccharomyces cerevisiae Ste50 SAM domain==
	<StructureSection load='1z1v' size='340' side='right' caption='[[1z1v]], [[NMR_Ensembles_of_Models \| 1 NMR models]]' scene=''>		<StructureSection load='1z1v' size='340' side='right' caption='[[1z1v]], [[NMR_Ensembles_of_Models \| 1 NMR models]]' scene=''>
Line 5:		Line 6:
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1uqv\|1uqv]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1uqv\|1uqv]]</td></tr>
	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">STE50 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=4932 ATCC 18824])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">STE50 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=4932 ATCC 18824])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1z1v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1z1v OCA], [http://pdbe.org/1z1v PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1z1v RCSB], [http://www.ebi.ac.uk/pdbsum/1z1v PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1z1v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1z1v OCA], [http://pdbe.org/1z1v PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1z1v RCSB], [http://www.ebi.ac.uk/pdbsum/1z1v PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1z1v ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==

OCA at 23:12, 10 September 2015

OCA — Thu, 10 Sep 2015 23:12:48 GMT

←Older revision		Revision as of 23:12, 10 September 2015
Line 5:		Line 5:
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1uqv\|1uqv]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1uqv\|1uqv]]</td></tr>
	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">STE50 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=4932 ATCC 18824])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">STE50 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=4932 ATCC 18824])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1z1v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1z1v OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1z1v RCSB], [http://www.ebi.ac.uk/pdbsum/1z1v PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1z1v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1z1v OCA], [http://pdbe.org/1z1v PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1z1v RCSB], [http://www.ebi.ac.uk/pdbsum/1z1v PDBsum]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/STE50_YEAST STE50_YEAST]] Involved in growth arrest during conjugation. May interact with the G protein alpha subunit.
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 15:		Line 17:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 1z1v" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>

OCA at 22:42, 3 January 2015

OCA — Sat, 03 Jan 2015 22:42:42 GMT

←Older revision		Revision as of 22:42, 3 January 2015
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1z1v]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_18824 Atcc 18824]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Z1V OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1Z1V FirstGlance]. <br>		<table><tr><td colspan='2'>[[1z1v]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_18824 Atcc 18824]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Z1V OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1Z1V FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1uqv\|1uqv]]</td></tr>	+	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1uqv\|1uqv]]</td></tr>
-	<tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">STE50 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=4932 ATCC 18824])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">STE50 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=4932 ATCC 18824])</td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1z1v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1z1v OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1z1v RCSB], [http://www.ebi.ac.uk/pdbsum/1z1v PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1z1v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1z1v OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1z1v RCSB], [http://www.ebi.ac.uk/pdbsum/1z1v PDBsum]</span></td></tr>
-	<table>	+	</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 20:		Line 20:
	</StructureSection>		</StructureSection>
	[[Category: Atcc 18824]]		[[Category: Atcc 18824]]
-	[[Category: Donaldson, L W.]]	+	[[Category: Donaldson, L W]]
-	[[Category: Kwan, J J.]]	+	[[Category: Kwan, J J]]
-	[[Category: Maini, J.]]	+	[[Category: Maini, J]]
-	[[Category: Pawson, T.]]	+	[[Category: Pawson, T]]
-	[[Category: Warner, N.]]	+	[[Category: Warner, N]]
	[[Category: All helix protein]]		[[Category: All helix protein]]
	[[Category: Cell cycle]]		[[Category: Cell cycle]]
	[[Category: Sam domain]]		[[Category: Sam domain]]

OCA at 06:51, 9 June 2014

OCA — Mon, 09 Jun 2014 06:51:04 GMT

←Older revision		Revision as of 06:51, 9 June 2014
Line 1:		Line 1:
-	[[~~Image:~~1z1v.~~png~~\|~~left~~\|~~200px~~]]	+	==NMR structure of the Saccharomyces cerevisiae Ste50 SAM domain==
		+	<StructureSection load='1z1v' size='340' side='right' caption='[[1z1v]], [[NMR_Ensembles_of_Models \| 1 NMR models]]' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[1z1v]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_18824 Atcc 18824]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Z1V OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1Z1V FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1uqv\|1uqv]]</td></tr>
		+	<tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">STE50 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=4932 ATCC 18824])</td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1z1v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1z1v OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1z1v RCSB], [http://www.ebi.ac.uk/pdbsum/1z1v PDBsum]</span></td></tr>
		+	<table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	In Saccharomyces cerevisiae, signal transduction through pathways governing mating, osmoregulation, and nitrogen starvation depends upon a direct interaction between the sterile alpha motif (SAM) domains of the Ste11 mitogen-activated protein kinase kinase kinase (MAPKKK) and its regulator Ste50. Previously, we solved the NMR structure of the SAM domain from Ste11 and identified two mutants that diminished binding to the Ste50 SAM domain. Building upon the Ste11 study, we present the NMR structure of the monomeric Ste50 SAM domain and a series of mutants bearing substitutions at surface-exposed hydrophobic amino acid residues. The mid-loop (ML) region of Ste11-SAM, defined by helices H3 and H4 and the end-helix (EH) region of Ste50-SAM, defined by helix H5, were sensitive to substitution, indicating that these two surfaces contribute to the high-affinity interaction. The combination of two mutants, Ste11-SAM-L72R and Ste50-SAM-L69R, formed a high-affinity heterodimer unencumbered by competing homotypic interactions that had prevented earlier NMR studies of the wild-type complex. Yeast bearing mutations that prevented the heterotypic Ste11-Ste50 association in vitro presented signaling defects in the mating and high-osmolarity growth pathways.

-	~~{{STRUCTURE_1z1v\| PDB=1z1v \| SCENE= }}~~	+	Saccharomyces cerevisiae Ste50 binds the MAPKKK Ste11 through a head-to-tail SAM domain interaction.,Kwan JJ, Warner N, Maini J, Chan Tung KW, Zakaria H, Pawson T, Donaldson LW J Mol Biol. 2006 Feb 10;356(1):142-54. Epub 2005 Nov 28. PMID:16337230<ref>PMID:16337230</ref>

-	~~===NMR structure~~ of the ~~Saccharomyces cerevisiae Ste50 SAM domain===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_16337230}}~~	+	== References ==
-		+	<references/>
-	~~==About this Structure==~~	+	__TOC__
-	~~[[1z1v]] is a 1 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]~~. ~~Full experimental information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=1Z1V OCA].~~	+	</StructureSection>
-		+	[[Category: Atcc 18824]]
-	==~~Reference~~==	+
-	<~~ref group="xtra">PMID:016337230<~~/~~ref~~><~~references group="xtra"~~/>	+
-	[[Category: ~~Saccharomyces cerevisiae~~]]	+
	[[Category: Donaldson, L W.]]		[[Category: Donaldson, L W.]]
	[[Category: Kwan, J J.]]		[[Category: Kwan, J J.]]

OCA: Protected "1z1v" [edit=sysop:move=sysop]

OCA — Tue, 14 Aug 2012 17:34:42 GMT

Protected "1z1v" [edit=sysop:move=sysop]

←Older revision

Revision as of 17:34, 14 August 2012

OCA at 17:34, 14 August 2012

OCA — Tue, 14 Aug 2012 17:34:40 GMT

←Older revision		Revision as of 17:34, 14 August 2012
Line 1:		Line 1:
-	{{Seed}}
	[[Image:1z1v.png\|left\|200px]]		[[Image:1z1v.png\|left\|200px]]

-	<!--
-	The line below this paragraph, containing "STRUCTURE_1z1v", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_1z1v\| PDB=1z1v \| SCENE= }}		{{STRUCTURE_1z1v\| PDB=1z1v \| SCENE= }}

	===NMR structure of the Saccharomyces cerevisiae Ste50 SAM domain===		===NMR structure of the Saccharomyces cerevisiae Ste50 SAM domain===

-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_16337230}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where 16337230 is the PubMed ID number.
-	-->
	{{ABSTRACT_PUBMED_16337230}}		{{ABSTRACT_PUBMED_16337230}}

	==About this Structure==		==About this Structure==
-	~~1Z1V is a~~ [[~~Single protein~~]] structure of sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Z1V OCA].	+	[[1z1v]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Z1V OCA].

	==Reference==		==Reference==
-	Saccharomyces cerevisiae Ste50 binds the MAPKKK Ste11 through a head-to-tail SAM domain interaction., Kwan JJ, Warner N, Maini J, Chan Tung KW, Zakaria H, Pawson T, Donaldson LW, J Mol Biol. 2006 Feb 10;356(1):142-54. Epub 2005 Nov 28. PMID:~~[http://www.ncbi.nlm.nih.gov~~/~~pubmed~~/~~16337230 16337230]~~	+	<ref group="xtra">PMID:016337230</ref><references group="xtra"/>
	[[Category: Saccharomyces cerevisiae]]		[[Category: Saccharomyces cerevisiae]]
-	[[Category: Single protein]]
	[[Category: Donaldson, L W.]]		[[Category: Donaldson, L W.]]
	[[Category: Kwan, J J.]]		[[Category: Kwan, J J.]]
Line 32:		Line 19:
	[[Category: Warner, N.]]		[[Category: Warner, N.]]
	[[Category: All helix protein]]		[[Category: All helix protein]]
		+	[[Category: Cell cycle]]
	[[Category: Sam domain]]		[[Category: Sam domain]]
-
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 14:24:53 2008''

OCA at 11:25, 28 July 2008

OCA — Mon, 28 Jul 2008 11:25:00 GMT

←Older revision		Revision as of 11:25, 28 July 2008
Line 1:		Line 1:
-	[[Image:1z1v.~~gif~~\|left\|200px]]	+	{{Seed}}
		+	[[Image:1z1v.png\|left\|200px]]

	<!--		<!--
Line 9:		Line 10:
	{{STRUCTURE_1z1v\| PDB=1z1v \| SCENE= }}		{{STRUCTURE_1z1v\| PDB=1z1v \| SCENE= }}

-	~~'''~~NMR structure of the Saccharomyces cerevisiae Ste50 SAM domain~~'''~~	+	===NMR structure of the Saccharomyces cerevisiae Ste50 SAM domain===


-	~~==Overview==~~	+	<!--
-	~~In Saccharomyces cerevisiae~~, ~~signal transduction through pathways governing mating~~, ~~osmoregulation, and nitrogen starvation depends upon a direct interaction between~~ the ~~sterile alpha motif (SAM) domains of~~ the ~~Ste11 mitogen-activated protein kinase kinase kinase~~ (~~MAPKKK) and its regulator Ste50~~. ~~Previously, we solved the NMR structure of the SAM domain from Ste11 and identified two mutants that diminished binding to the Ste50 SAM domain~~. Building upon the Ste11 study, we present the NMR structure of the monomeric Ste50 SAM domain and a series of mutants bearing substitutions at surface-exposed hydrophobic amino acid residues. The mid-loop (ML) ~~region of Ste11-SAM~~, ~~defined by helices H3 and H4 and~~ the ~~end-helix (EH) region of Ste50-SAM, defined by helix H5, were sensitive to substitution, indicating that these two surfaces contribute to the high-affinity interaction~~. ~~The combination of two mutants, Ste11~~-~~SAM~~-L72R and Ste50-SAM-L69R, formed a high-affinity heterodimer unencumbered by competing homotypic interactions that had prevented earlier NMR studies of the wild-type complex. Yeast bearing mutations that prevented the heterotypic Ste11-Ste50 association in vitro presented signaling defects in the mating and high-osmolarity growth pathways.	+	The line below this paragraph, {{ABSTRACT_PUBMED_16337230}}, adds the Publication Abstract to the page
		+	(as it appears on PubMed at http://www.pubmed.gov), where 16337230 is the PubMed ID number.
		+	-->
		+	{{ABSTRACT_PUBMED_16337230}}

	==About this Structure==		==About this Structure==
-	1Z1V is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full ~~crystallographic~~ information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Z1V OCA].	+	1Z1V is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Z1V OCA].

	==Reference==		==Reference==
Line 29:		Line 33:
	[[Category: All helix protein]]		[[Category: All helix protein]]
	[[Category: Sam domain]]		[[Category: Sam domain]]
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on ~~Sat May 3 17~~:05:09 2008''	+
		+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 14:24:53 2008''