1z8v - Revision history

OCA at 09:02, 14 February 2024

OCA — Wed, 14 Feb 2024 09:02:51 GMT

←Older revision		Revision as of 09:02, 14 February 2024
Line 8:		Line 8:
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1z8v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1z8v OCA], [https://pdbe.org/1z8v PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1z8v RCSB], [https://www.ebi.ac.uk/pdbsum/1z8v PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1z8v ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1z8v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1z8v OCA], [https://pdbe.org/1z8v PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1z8v RCSB], [https://www.ebi.ac.uk/pdbsum/1z8v PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1z8v ProSAT]</span></td></tr>
	</table>		</table>
-	<div style="background-color:#fffaf0;">
-	== Publication Abstract from PubMed ==
-	The structure of the complex between the minor groove binder netropsin and d(GGCCAATTGG) was determined via single-crystal X-ray techniques. The structure was refined to completion using refmac5.1.24, resulting in a residual R-factor of 20.0% (including 68 water molecules). Using crystal engineering and cryocooling techniques, the resolution could be enhanced to 1.75 A, resulting in an unambiguous determination of the drug conformation and orientation. As previously noticed, bifurcated hydrogen bonds are formed between the amide nitrogen atoms of the drug and the N3 and O2 atoms of A and T base pairs, respectively, clearly cataloging the structure to class I. As the bulky NH2 group on guanine was believed to prevent binding of the drug in the minor groove, the detailed nature of several of the amidinium and guanidinium end contacts were further investigated by ab initio quantum chemical methods.
-
-	Netropsin interactions in the minor groove of d(GGCCAATTGG) studied by a combination of resolution enhancement and ab initio calculations.,Van Hecke K, Nam PC, Nguyen MT, Van Meervelt L FEBS J. 2005 Jul;272(14):3531-41. PMID:16008554<ref>PMID:16008554</ref>
-
-	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	</div>
-	<div class="pdbe-citations 1z8v" style="background-color:#fffaf0;"></div>
-	== References ==
-	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>

OCA at 10:30, 16 August 2023

OCA — Wed, 16 Aug 2023 10:30:31 GMT

←Older revision		Revision as of 10:30, 16 August 2023
Line 4:		Line 4:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1z8v]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Z8V OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1Z8V FirstGlance]. <br>		<table><tr><td colspan='2'>[[1z8v]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Z8V OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1Z8V FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NT:NETROPSIN'>NT</scene></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.75Å</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NT:NETROPSIN'>NT</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1z8v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1z8v OCA], [https://pdbe.org/1z8v PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1z8v RCSB], [https://www.ebi.ac.uk/pdbsum/1z8v PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1z8v ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1z8v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1z8v OCA], [https://pdbe.org/1z8v PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1z8v RCSB], [https://www.ebi.ac.uk/pdbsum/1z8v PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1z8v ProSAT]</span></td></tr>
	</table>		</table>
Line 21:		Line 22:
	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	~~[[Category: Hecke, K Van]]~~	+	[[Category: Nam PC]]
-	~~[[Category: Meervelt, L Van]]~~	+	[[Category: Nguyen MT]]
-	[[Category: Nam~~, P C~~]]	+	[[Category: Van Hecke K]]
-	[[Category: Nguyen~~, M T~~]]	+	[[Category: Van Meervelt L]]
-	[[Category: ~~B-dna double helix~~]]	+
-	[[Category: ~~Base triplet]]~~	+
-	~~[[Category: Dna]]~~	+
-	~~[[Category: Drug]]~~	+
-	~~[[Category: Minor groove binder]]~~	+
-	~~[[Category: Netropsin~~]]	+

OCA at 08:18, 10 November 2021

OCA — Wed, 10 Nov 2021 08:18:31 GMT

←Older revision		Revision as of 08:18, 10 November 2021
Line 3:		Line 3:
	<StructureSection load='1z8v' size='340' side='right'caption='[[1z8v]], [[Resolution\|resolution]] 1.75Å' scene=''>		<StructureSection load='1z8v' size='340' side='right'caption='[[1z8v]], [[Resolution\|resolution]] 1.75Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1z8v]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Z8V OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1Z8V FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1z8v]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Z8V OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1Z8V FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NT:NETROPSIN'>NT</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NT:NETROPSIN'>NT</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1z8v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1z8v OCA], [~~http~~://pdbe.org/1z8v PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=1z8v RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/1z8v PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=1z8v ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1z8v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1z8v OCA], [https://pdbe.org/1z8v PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1z8v RCSB], [https://www.ebi.ac.uk/pdbsum/1z8v PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1z8v ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 09:31, 5 February 2020

OCA — Wed, 05 Feb 2020 09:31:32 GMT

←Older revision		Revision as of 09:31, 5 February 2020
Line 1:		Line 1:

	==The Structure of d(GGCCAATTGG) Complexed with Netropsin==		==The Structure of d(GGCCAATTGG) Complexed with Netropsin==
-	<StructureSection load='1z8v' size='340' side='right' caption='[[1z8v]], [[Resolution\|resolution]] 1.75Å' scene=''>	+	<StructureSection load='1z8v' size='340' side='right'caption='[[1z8v]], [[Resolution\|resolution]] 1.75Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1z8v]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Z8V OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1Z8V FirstGlance]. <br>		<table><tr><td colspan='2'>[[1z8v]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Z8V OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1Z8V FirstGlance]. <br>
Line 20:		Line 20:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Large Structures]]
	[[Category: Hecke, K Van]]		[[Category: Hecke, K Van]]
	[[Category: Meervelt, L Van]]		[[Category: Meervelt, L Van]]

OCA at 08:57, 2 May 2018

OCA — Wed, 02 May 2018 08:57:09 GMT

←Older revision		Revision as of 08:57, 2 May 2018
Line 1:		Line 1:
		+
	==The Structure of d(GGCCAATTGG) Complexed with Netropsin==		==The Structure of d(GGCCAATTGG) Complexed with Netropsin==
	<StructureSection load='1z8v' size='340' side='right' caption='[[1z8v]], [[Resolution\|resolution]] 1.75Å' scene=''>		<StructureSection load='1z8v' size='340' side='right' caption='[[1z8v]], [[Resolution\|resolution]] 1.75Å' scene=''>
Line 4:		Line 5:
	<table><tr><td colspan='2'>[[1z8v]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Z8V OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1Z8V FirstGlance]. <br>		<table><tr><td colspan='2'>[[1z8v]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Z8V OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1Z8V FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NT:NETROPSIN'>NT</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NT:NETROPSIN'>NT</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1z8v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1z8v OCA], [http://pdbe.org/1z8v PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1z8v RCSB], [http://www.ebi.ac.uk/pdbsum/1z8v PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1z8v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1z8v OCA], [http://pdbe.org/1z8v PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1z8v RCSB], [http://www.ebi.ac.uk/pdbsum/1z8v PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1z8v ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 04:02, 10 September 2015

OCA — Thu, 10 Sep 2015 04:02:48 GMT

←Older revision		Revision as of 04:02, 10 September 2015
Line 4:		Line 4:
	<table><tr><td colspan='2'>[[1z8v]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Z8V OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1Z8V FirstGlance]. <br>		<table><tr><td colspan='2'>[[1z8v]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Z8V OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1Z8V FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NT:NETROPSIN'>NT</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NT:NETROPSIN'>NT</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1z8v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1z8v OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1z8v RCSB], [http://www.ebi.ac.uk/pdbsum/1z8v PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1z8v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1z8v OCA], [http://pdbe.org/1z8v PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1z8v RCSB], [http://www.ebi.ac.uk/pdbsum/1z8v PDBsum]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 14:		Line 14:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 1z8v" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>

OCA at 05:12, 22 December 2014

OCA — Mon, 22 Dec 2014 05:12:40 GMT

←Older revision		Revision as of 05:12, 22 December 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1z8v]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Z8V OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1Z8V FirstGlance]. <br>		<table><tr><td colspan='2'>[[1z8v]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Z8V OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1Z8V FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NT:NETROPSIN'>NT</scene><br>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NT:NETROPSIN'>NT</scene></td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1z8v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1z8v OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1z8v RCSB], [http://www.ebi.ac.uk/pdbsum/1z8v PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1z8v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1z8v OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1z8v RCSB], [http://www.ebi.ac.uk/pdbsum/1z8v PDBsum]</span></td></tr>
-	<table>	+	</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 18:		Line 18:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Hecke, K Van.]]	+	[[Category: Hecke, K Van]]
-	[[Category: Meervelt, L Van.]]	+	[[Category: Meervelt, L Van]]
-	[[Category: Nam, P C.]]	+	[[Category: Nam, P C]]
-	[[Category: Nguyen, M T.]]	+	[[Category: Nguyen, M T]]
	[[Category: B-dna double helix]]		[[Category: B-dna double helix]]
	[[Category: Base triplet]]		[[Category: Base triplet]]

OCA at 06:54, 9 June 2014

OCA — Mon, 09 Jun 2014 06:54:30 GMT

←Older revision		Revision as of 06:54, 9 June 2014
Line 1:		Line 1:
-	[[~~Image:~~1z8v.~~png~~\|~~left\|200px~~]]	+	==The Structure of d(GGCCAATTGG) Complexed with Netropsin==
		+	<StructureSection load='1z8v' size='340' side='right' caption='[[1z8v]], [[Resolution\|resolution]] 1.75Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[1z8v]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Z8V OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1Z8V FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NT:NETROPSIN'>NT</scene><br>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1z8v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1z8v OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1z8v RCSB], [http://www.ebi.ac.uk/pdbsum/1z8v PDBsum]</span></td></tr>
		+	<table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	The structure of the complex between the minor groove binder netropsin and d(GGCCAATTGG) was determined via single-crystal X-ray techniques. The structure was refined to completion using refmac5.1.24, resulting in a residual R-factor of 20.0% (including 68 water molecules). Using crystal engineering and cryocooling techniques, the resolution could be enhanced to 1.75 A, resulting in an unambiguous determination of the drug conformation and orientation. As previously noticed, bifurcated hydrogen bonds are formed between the amide nitrogen atoms of the drug and the N3 and O2 atoms of A and T base pairs, respectively, clearly cataloging the structure to class I. As the bulky NH2 group on guanine was believed to prevent binding of the drug in the minor groove, the detailed nature of several of the amidinium and guanidinium end contacts were further investigated by ab initio quantum chemical methods.

-	~~{{STRUCTURE_1z8v\| PDB=1z8v \| SCENE= }}~~	+	Netropsin interactions in the minor groove of d(GGCCAATTGG) studied by a combination of resolution enhancement and ab initio calculations.,Van Hecke K, Nam PC, Nguyen MT, Van Meervelt L FEBS J. 2005 Jul;272(14):3531-41. PMID:16008554<ref>PMID:16008554</ref>

-	~~===The Structure~~ of ~~d(GGCCAATTGG) Complexed with Netropsin===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_16008554}}~~	+	== References ==
-		+	<references/>
-	~~==About this Structure==~~	+	__TOC__
-	~~[[1z8v]] is a 2 chain structure~~. ~~Full crystallographic information is available from [http://oca~~.~~weizmann~~.~~ac.il~~/~~oca-bin/ocashort?id=1Z8V OCA].~~	+	</StructureSection>
-		+
-	==~~Reference~~==	+
-	<~~ref group="xtra">PMID:016008554<~~/~~ref~~><~~references group="xtra"~~/>	+
	[[Category: Hecke, K Van.]]		[[Category: Hecke, K Van.]]
	[[Category: Meervelt, L Van.]]		[[Category: Meervelt, L Van.]]

OCA: Protected "1z8v" [edit=sysop:move=sysop]

OCA — Tue, 14 Aug 2012 15:16:25 GMT

Protected "1z8v" [edit=sysop:move=sysop]

←Older revision

Revision as of 15:16, 14 August 2012

OCA at 15:16, 14 August 2012

OCA — Tue, 14 Aug 2012 15:16:23 GMT

←Older revision		Revision as of 15:16, 14 August 2012
Line 1:		Line 1:
-	{{Seed}}
	[[Image:1z8v.png\|left\|200px]]		[[Image:1z8v.png\|left\|200px]]

-	<!--
-	The line below this paragraph, containing "STRUCTURE_1z8v", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_1z8v\| PDB=1z8v \| SCENE= }}		{{STRUCTURE_1z8v\| PDB=1z8v \| SCENE= }}

	===The Structure of d(GGCCAATTGG) Complexed with Netropsin===		===The Structure of d(GGCCAATTGG) Complexed with Netropsin===

-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_16008554}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where 16008554 is the PubMed ID number.
-	-->
	{{ABSTRACT_PUBMED_16008554}}		{{ABSTRACT_PUBMED_16008554}}

	==About this Structure==		==About this Structure==
-	Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Z8V OCA].	+	[[1z8v]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Z8V OCA].

	==Reference==		==Reference==
-	Netropsin interactions in the minor groove of d(GGCCAATTGG) studied by a combination of resolution enhancement and ab initio calculations., Van Hecke K, Nam PC, Nguyen MT, Van Meervelt L, FEBS J. 2005 Jul;272(14):3531-41. PMID:~~[http://www.ncbi.nlm.nih.gov~~/~~pubmed~~/~~16008554 16008554]~~	+	<ref group="xtra">PMID:016008554</ref><references group="xtra"/>
	[[Category: Hecke, K Van.]]		[[Category: Hecke, K Van.]]
	[[Category: Meervelt, L Van.]]		[[Category: Meervelt, L Van.]]
Line 30:		Line 18:
	[[Category: B-dna double helix]]		[[Category: B-dna double helix]]
	[[Category: Base triplet]]		[[Category: Base triplet]]
		+	[[Category: Dna]]
	[[Category: Drug]]		[[Category: Drug]]
	[[Category: Minor groove binder]]		[[Category: Minor groove binder]]
	[[Category: Netropsin]]		[[Category: Netropsin]]
-
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Jul 27 18:44:07 2008''