1zeq - Revision history

OCA at 09:04, 14 February 2024

OCA — Wed, 14 Feb 2024 09:04:08 GMT

←Older revision		Revision as of 09:04, 14 February 2024
Line 3:		Line 3:
	<StructureSection load='1zeq' size='340' side='right'caption='[[1zeq]], [[Resolution\|resolution]] 1.50Å' scene=''>		<StructureSection load='1zeq' size='340' side='right'caption='[[1zeq]], [[Resolution\|resolution]] 1.50Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1zeq]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~"bacillus_coli"_migula_1895 "bacillus~~ coli~~" migula 1895~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZEQ OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=1ZEQ FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1zeq]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZEQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1ZEQ FirstGlance]. <br>
-	</td></tr><tr id='~~gene~~'><td class="sblockLbl"><b>[[~~Gene~~\|~~Gene~~:]]</b></td><td class="sblockDat">~~cusF~~, ~~cusX (~~[~~http://www~~.~~ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=~~5&~~id=562 "Bacillus coli" Migula 1895])~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.5Å</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=1zeq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1zeq OCA], [~~http~~://pdbe.org/1zeq PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=1zeq RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/1zeq PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=1zeq ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1zeq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1zeq OCA], [https://pdbe.org/1zeq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1zeq RCSB], [https://www.ebi.ac.uk/pdbsum/1zeq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1zeq ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[~~[http~~://www.uniprot.org/uniprot/CUSF_ECOLI CUSF_ECOLI]] Part of a cation efflux system that mediates resistance to copper and silver. Binds one copper per polypeptide.<ref>PMID:11399769</ref>	+	[https://www.uniprot.org/uniprot/CUSF_ECOLI CUSF_ECOLI] Part of a cation efflux system that mediates resistance to copper and silver. Binds one copper per polypeptide.<ref>PMID:11399769</ref>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 19:		Line 19:
	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1zeq ConSurf].		</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1zeq ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
-	<div style="background-color:#fffaf0;">
-	== Publication Abstract from PubMed ==
-	We have determined the crystal structure of apo-CusF, a periplasmic protein involved in copper and silver resistance in Escherichia coli. The protein forms a five-stranded beta-barrel, classified as an OB-fold, which is a unique topology for a copper-binding protein. NMR chemical shift mapping experiments suggest that Cu(I) is bound by conserved residues H36, M47, and M49 located in beta-strands 2 and 3. These residues are clustered at one end of the beta-barrel, and their side chains are oriented toward the interior of the barrel. Cu(I) can be modeled into the apo-CusF structure with only minimal structural changes using H36, M47, and M49 as ligands. The unique structure and metal binding site of CusF are distinct from those of previously characterized copper-binding proteins.
-
-	A novel copper-binding fold for the periplasmic copper resistance protein CusF.,Loftin IR, Franke S, Roberts SA, Weichsel A, Heroux A, Montfort WR, Rensing C, McEvoy MM Biochemistry. 2005 Aug 9;44(31):10533-40. PMID:16060662<ref>PMID:16060662</ref>
-
-	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	</div>
-	<div class="pdbe-citations 1zeq" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Bacillus~~ coli ~~migula 1895~~]]	+	[[Category: Escherichia coli]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Franke, S]]	+	[[Category: Franke S]]
-	[[Category: Heroux, A]]	+	[[Category: Heroux A]]
-	[[Category: Loftin~~, I R~~]]	+	[[Category: Loftin IR]]
-	[[Category: McEvoy~~, M M~~]]	+	[[Category: McEvoy MM]]
-	[[Category: Montfort~~, W R~~]]	+	[[Category: Montfort WR]]
-	[[Category: Rensing, C]]	+	[[Category: Rensing C]]
-	[[Category: Roberts~~, S A~~]]	+	[[Category: Roberts SA]]
-	[[Category: Weichsel, A]]	+	[[Category: Weichsel A]]
-	~~[[Category: Beta barrel]]~~	+
-	~~[[Category: Copper-binding]]~~	+
-	~~[[Category: Metal binding protein]]~~	+
-	~~[[Category: Metallochaperone]]~~	+
-	~~[[Category: Ob-fold~~]]	+

OCA at 09:03, 20 January 2021

OCA — Wed, 20 Jan 2021 09:03:07 GMT

←Older revision		Revision as of 09:03, 20 January 2021
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	==1.5 A Structure of apo-CusF residues 6-88 from Escherichia coli==		==1.5 A Structure of apo-CusF residues 6-88 from Escherichia coli==
-	<StructureSection load='1zeq' size='340' side='right' caption='[[1zeq]], [[Resolution\|resolution]] 1.50Å' scene=''>	+	<StructureSection load='1zeq' size='340' side='right'caption='[[1zeq]], [[Resolution\|resolution]] 1.50Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1zeq]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZEQ OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1ZEQ FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1zeq]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZEQ OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=1ZEQ FirstGlance]. <br>
	</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">cusF, cusX ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 "Bacillus coli" Migula 1895])</td></tr>		</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">cusF, cusX ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 "Bacillus coli" Migula 1895])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1zeq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1zeq OCA], [http://pdbe.org/1zeq PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1zeq RCSB], [http://www.ebi.ac.uk/pdbsum/1zeq PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1zeq ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=1zeq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1zeq OCA], [http://pdbe.org/1zeq PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1zeq RCSB], [http://www.ebi.ac.uk/pdbsum/1zeq PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1zeq ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 33:		Line 33:
	</StructureSection>		</StructureSection>
	[[Category: Bacillus coli migula 1895]]		[[Category: Bacillus coli migula 1895]]
		+	[[Category: Large Structures]]
	[[Category: Franke, S]]		[[Category: Franke, S]]
	[[Category: Heroux, A]]		[[Category: Heroux, A]]

OCA at 08:54, 2 May 2018

OCA — Wed, 02 May 2018 08:54:33 GMT

←Older revision		Revision as of 08:54, 2 May 2018
Line 1:		Line 1:
		+
	==1.5 A Structure of apo-CusF residues 6-88 from Escherichia coli==		==1.5 A Structure of apo-CusF residues 6-88 from Escherichia coli==
	<StructureSection load='1zeq' size='340' side='right' caption='[[1zeq]], [[Resolution\|resolution]] 1.50Å' scene=''>		<StructureSection load='1zeq' size='340' side='right' caption='[[1zeq]], [[Resolution\|resolution]] 1.50Å' scene=''>
Line 4:		Line 5:
	<table><tr><td colspan='2'>[[1zeq]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZEQ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ZEQ FirstGlance]. <br>		<table><tr><td colspan='2'>[[1zeq]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZEQ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ZEQ FirstGlance]. <br>
	</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">cusF, cusX ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 "Bacillus coli" Migula 1895])</td></tr>		</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">cusF, cusX ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 "Bacillus coli" Migula 1895])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1zeq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1zeq OCA], [http://pdbe.org/1zeq PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1zeq RCSB], [http://www.ebi.ac.uk/pdbsum/1zeq PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1zeq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1zeq OCA], [http://pdbe.org/1zeq PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1zeq RCSB], [http://www.ebi.ac.uk/pdbsum/1zeq PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1zeq ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 12:		Line 13:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ze/1zeq_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ze/1zeq_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1zeq ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 10:33, 11 September 2015

OCA — Fri, 11 Sep 2015 10:33:27 GMT

←Older revision		Revision as of 10:33, 11 September 2015
Line 2:		Line 2:
	<StructureSection load='1zeq' size='340' side='right' caption='[[1zeq]], [[Resolution\|resolution]] 1.50Å' scene=''>		<StructureSection load='1zeq' size='340' side='right' caption='[[1zeq]], [[Resolution\|resolution]] 1.50Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1zeq]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Escherichia_coli Escherichia~~ coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZEQ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ZEQ FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1zeq]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZEQ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ZEQ FirstGlance]. <br>
-	</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">cusF, cusX ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 ~~Escherichia~~ coli])</td></tr>	+	</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">cusF, cusX ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 "Bacillus coli" Migula 1895])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1zeq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1zeq OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1zeq RCSB], [http://www.ebi.ac.uk/pdbsum/1zeq PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1zeq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1zeq OCA], [http://pdbe.org/1zeq PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1zeq RCSB], [http://www.ebi.ac.uk/pdbsum/1zeq PDBsum]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 26:		Line 26:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 1zeq" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Escherichia~~ coli]]	+	[[Category: Bacillus coli migula 1895]]
	[[Category: Franke, S]]		[[Category: Franke, S]]
	[[Category: Heroux, A]]		[[Category: Heroux, A]]

OCA at 15:16, 25 December 2014

OCA — Thu, 25 Dec 2014 15:16:17 GMT

←Older revision		Revision as of 15:16, 25 December 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1zeq]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZEQ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ZEQ FirstGlance]. <br>		<table><tr><td colspan='2'>[[1zeq]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZEQ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ZEQ FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">cusF, cusX ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 Escherichia coli])</td></tr>	+	</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">cusF, cusX ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 Escherichia coli])</td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1zeq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1zeq OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1zeq RCSB], [http://www.ebi.ac.uk/pdbsum/1zeq PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1zeq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1zeq OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1zeq RCSB], [http://www.ebi.ac.uk/pdbsum/1zeq PDBsum]</span></td></tr>
-	<table>	+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/CUSF_ECOLI CUSF_ECOLI]] Part of a cation efflux system that mediates resistance to copper and silver. Binds one copper per polypeptide.<ref>PMID:11399769</ref>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 29:		Line 31:
	</StructureSection>		</StructureSection>
	[[Category: Escherichia coli]]		[[Category: Escherichia coli]]
-	[[Category: Franke, S.]]	+	[[Category: Franke, S]]
-	[[Category: Heroux, A.]]	+	[[Category: Heroux, A]]
-	[[Category: Loftin, I R.]]	+	[[Category: Loftin, I R]]
-	[[Category: McEvoy, M M.]]	+	[[Category: McEvoy, M M]]
-	[[Category: Montfort, W R.]]	+	[[Category: Montfort, W R]]
-	[[Category: Rensing, C.]]	+	[[Category: Rensing, C]]
-	[[Category: Roberts, S A.]]	+	[[Category: Roberts, S A]]
-	[[Category: Weichsel, A.]]	+	[[Category: Weichsel, A]]
	[[Category: Beta barrel]]		[[Category: Beta barrel]]
	[[Category: Copper-binding]]		[[Category: Copper-binding]]

OCA at 18:26, 29 September 2014

OCA — Mon, 29 Sep 2014 18:26:21 GMT

←Older revision		Revision as of 18:26, 29 September 2014
Line 1:		Line 1:
-	[[~~Image~~:1zeq.~~png\|left~~\|200px]]	+	==1.5 A Structure of apo-CusF residues 6-88 from Escherichia coli==
		+	<StructureSection load='1zeq' size='340' side='right' caption='[[1zeq]], [[Resolution\|resolution]] 1.50Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[1zeq]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZEQ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ZEQ FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">cusF, cusX ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 Escherichia coli])</td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1zeq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1zeq OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1zeq RCSB], [http://www.ebi.ac.uk/pdbsum/1zeq PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ze/1zeq_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	We have determined the crystal structure of apo-CusF, a periplasmic protein involved in copper and silver resistance in Escherichia coli. The protein forms a five-stranded beta-barrel, classified as an OB-fold, which is a unique topology for a copper-binding protein. NMR chemical shift mapping experiments suggest that Cu(I) is bound by conserved residues H36, M47, and M49 located in beta-strands 2 and 3. These residues are clustered at one end of the beta-barrel, and their side chains are oriented toward the interior of the barrel. Cu(I) can be modeled into the apo-CusF structure with only minimal structural changes using H36, M47, and M49 as ligands. The unique structure and metal binding site of CusF are distinct from those of previously characterized copper-binding proteins.

-	~~{{STRUCTURE_1zeq\| PDB=1zeq \| SCENE= }}~~	+	A novel copper-binding fold for the periplasmic copper resistance protein CusF.,Loftin IR, Franke S, Roberts SA, Weichsel A, Heroux A, Montfort WR, Rensing C, McEvoy MM Biochemistry. 2005 Aug 9;44(31):10533-40. PMID:16060662<ref>PMID:16060662</ref>

-	~~===1.5 A Structure~~ of ~~apo-CusF residues 6-88 from Escherichia coli===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_16060662}}~~	+	== References ==
-		+	<references/>
-	~~==About this Structure==~~	+	__TOC__
-	~~[[1zeq]] is a 1 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Escherichia_coli Escherichia coli]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=1ZEQ OCA].~~	+	</StructureSection>
-		+
-	==~~Reference~~==	+
-	<~~ref group="xtra">PMID:016060662<~~/~~ref~~><~~references group="xtra"~~/>	+
	[[Category: Escherichia coli]]		[[Category: Escherichia coli]]
	[[Category: Franke, S.]]		[[Category: Franke, S.]]

OCA: Protected "1zeq" [edit=sysop:move=sysop]

OCA — Sat, 05 Jan 2013 17:10:27 GMT

Protected "1zeq" [edit=sysop:move=sysop]

←Older revision

Revision as of 17:10, 5 January 2013

OCA at 17:10, 5 January 2013

OCA — Sat, 05 Jan 2013 17:10:22 GMT

←Older revision		Revision as of 17:10, 5 January 2013
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-	{{Seed}}
	[[Image:1zeq.png\|left\|200px]]		[[Image:1zeq.png\|left\|200px]]

-	<!--
-	The line below this paragraph, containing "STRUCTURE_1zeq", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_1zeq\| PDB=1zeq \| SCENE= }}		{{STRUCTURE_1zeq\| PDB=1zeq \| SCENE= }}

	===1.5 A Structure of apo-CusF residues 6-88 from Escherichia coli===		===1.5 A Structure of apo-CusF residues 6-88 from Escherichia coli===

-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_16060662}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where 16060662 is the PubMed ID number.
-	-->
	{{ABSTRACT_PUBMED_16060662}}		{{ABSTRACT_PUBMED_16060662}}

	==About this Structure==		==About this Structure==
-	~~1ZEQ~~ is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZEQ OCA].	+	[[1zeq]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZEQ OCA].

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~16060662~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:016060662</ref><references group="xtra"/>
	[[Category: Escherichia coli]]		[[Category: Escherichia coli]]
	[[Category: Franke, S.]]		[[Category: Franke, S.]]
Line 35:		Line 23:
	[[Category: Beta barrel]]		[[Category: Beta barrel]]
	[[Category: Copper-binding]]		[[Category: Copper-binding]]
		+	[[Category: Metal binding protein]]
	[[Category: Metallochaperone]]		[[Category: Metallochaperone]]
	[[Category: Ob-fold]]		[[Category: Ob-fold]]
-
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 20:00:06 2009''

OCA at 18:00, 17 February 2009

OCA — Tue, 17 Feb 2009 18:00:06 GMT

←Older revision		Revision as of 18:00, 17 February 2009
Line 20:		Line 20:

	==About this Structure==		==About this Structure==
-	1ZEQ is a ~~[[Single protein]]~~ structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZEQ OCA].	+	1ZEQ is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZEQ OCA].

	==Reference==		==Reference==
-	A novel copper-binding fold for the periplasmic copper resistance protein CusF., Loftin IR, Franke S, Roberts SA, Weichsel A, Heroux A, Montfort WR, Rensing C, McEvoy MM, Biochemistry. 2005 Aug 9;44(31):10533-40. PMID:~~[http:~~//~~www.ncbi.nlm.nih.gov/pubmed/16060662 16060662]~~	+	<ref group="xtra">PMID:16060662</ref><references group="xtra"/>
	[[Category: Escherichia coli]]		[[Category: Escherichia coli]]
-	[[Category: Single protein]]
	[[Category: Franke, S.]]		[[Category: Franke, S.]]
	[[Category: Heroux, A.]]		[[Category: Heroux, A.]]
Line 39:		Line 38:
	[[Category: Ob-fold]]		[[Category: Ob-fold]]

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue ~~Jul 29 03~~:53:~~56 2008~~''	+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 20:00:06 2009''

OCA at 00:53, 29 July 2008

OCA — Tue, 29 Jul 2008 00:53:58 GMT

←Older revision		Revision as of 00:53, 29 July 2008
Line 1:		Line 1:
-	[[Image:1zeq.~~gif~~\|left\|200px]]	+	{{Seed}}
		+	[[Image:1zeq.png\|left\|200px]]

	<!--		<!--
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	{{STRUCTURE_1zeq\| PDB=1zeq \| SCENE= }}		{{STRUCTURE_1zeq\| PDB=1zeq \| SCENE= }}

-	~~'''~~1.5 A Structure of apo-CusF residues 6-88 from Escherichia coli~~'''~~	+	===1.5 A Structure of apo-CusF residues 6-88 from Escherichia coli===


-	~~==Overview==~~	+	<!--
-	~~We have determined the crystal structure of apo-CusF, a periplasmic protein involved in copper and silver resistance in Escherichia coli.~~ The ~~protein forms a five-stranded beta-barrel~~, ~~classified as an OB-fold~~, ~~which is a unique topology for a copper-binding protein. NMR chemical shift mapping experiments suggest that Cu~~(~~I) is bound by conserved residues H36, M47, and M49 located in beta-strands 2 and 3. These residues are clustered~~ at ~~one end of the beta-barrel, and their side chains are oriented toward the interior of the barrel~~. ~~Cu(I~~) ~~can be modeled into~~ the ~~apo-CusF structure with only minimal structural changes using H36, M47, and M49 as ligands~~. ~~The unique structure and metal binding site of CusF are distinct from those of previously characterized copper~~-~~binding proteins.~~	+	The line below this paragraph, {{ABSTRACT_PUBMED_16060662}}, adds the Publication Abstract to the page
		+	(as it appears on PubMed at http://www.pubmed.gov), where 16060662 is the PubMed ID number.
		+	-->
		+	{{ABSTRACT_PUBMED_16060662}}

	==About this Structure==		==About this Structure==
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	[[Category: Metallochaperone]]		[[Category: Metallochaperone]]
	[[Category: Ob-fold]]		[[Category: Ob-fold]]
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on ~~Sat May 3 17~~:32:08 2008''	+
		+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 29 03:53:56 2008''