1zng - Revision history

OCA at 07:11, 23 August 2023

OCA — Wed, 23 Aug 2023 07:11:37 GMT

←Older revision		Revision as of 07:11, 23 August 2023
Line 3:		Line 3:
	<StructureSection load='1zng' size='340' side='right'caption='[[1zng]], [[Resolution\|resolution]] 1.60Å' scene=''>		<StructureSection load='1zng' size='340' side='right'caption='[[1zng]], [[Resolution\|resolution]] 1.60Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1zng]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Lk3_transgenic_mice Lk3 transgenic mice~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZNG OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=1ZNG FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1zng]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZNG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1ZNG FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=CD:CADMIUM+ION'>CD</scene>~~, ~~<scene name='pdbligand=HE4:HEPTAN-~~1~~-OL'>HE4</scene>~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.6Å</td></tr>
-	<tr id='~~related~~'><td class="sblockLbl"><b>[[~~Related_structure~~\|~~Related~~:]]</b></td><td class="sblockDat"><~~div style~~='~~overflow~~: ~~auto; max-height: 3em;~~'>~~[[1znd\|1znd]], [[1zne\|1zne]], [[1znh\|1znh]], [[1znk\|1znk]], [[1znl\|1znl]]~~</~~div~~><~~/td></tr>~~	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CD:CADMIUM+ION'>CD</scene>, <scene name='pdbligand=HE4:HEPTAN-1-OL'>HE4</scene></td></tr>
-	~~<tr id~~='~~gene'><td class~~=~~"sblockLbl"><b>[[Gene\|Gene~~:~~]]</b~~></td>~~<td class="sblockDat">MUP1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 LK3 transgenic mice])~~</td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1zng FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1zng OCA], [https://pdbe.org/1zng PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1zng RCSB], [https://www.ebi.ac.uk/pdbsum/1zng PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1zng ProSAT]</span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=1zng FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1zng OCA], [~~http~~://pdbe.org/1zng PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=1zng RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/1zng PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=1zng ProSAT]</span></td></tr>	+
	</table>		</table>
	== Function ==		== Function ==
-	[~~[http~~://www.uniprot.org/uniprot/MUP2_MOUSE MUP2_MOUSE]] Binds pheromones that are released from drying urine of males. These pheromones affect the sexual behavior of females.	+	[https://www.uniprot.org/uniprot/MUP2_MOUSE MUP2_MOUSE] Binds pheromones that are released from drying urine of males. These pheromones affect the sexual behavior of females.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 35:		Line 34:
	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: ~~Lk3 transgenic mice~~]]	+	[[Category: Mus musculus]]
-	[[Category: Barratt, E]]	+	[[Category: Barratt E]]
-	[[Category: Bingham~~, R J~~]]	+	[[Category: Bingham RJ]]
-	[[Category: Homans~~, S W~~]]	+	[[Category: Homans SW]]
-	[[Category: Johnstone, S]]	+	[[Category: Johnstone S]]
-	[[Category: Laughton~~, C A~~]]	+	[[Category: Laughton CA]]
-	[[Category: Malham, R]]	+	[[Category: Malham R]]
-	[[Category: Phillips~~, S E]]~~	+	[[Category: Phillips SE]]
-	~~[[Category: Beta-barrel]]~~	+
-	~~[[Category: Lipocalin]]~~	+
-	~~[[Category: Transport protein~~]]	+

OCA at 09:07, 20 January 2021

OCA — Wed, 20 Jan 2021 09:07:27 GMT

←Older revision		Revision as of 09:07, 20 January 2021
Line 1:		Line 1:

	==Strong Solute-Solute Dispersive Interactions in a Protein-Ligand Complex==		==Strong Solute-Solute Dispersive Interactions in a Protein-Ligand Complex==
-	<StructureSection load='1zng' size='340' side='right' caption='[[1zng]], [[Resolution\|resolution]] 1.60Å' scene=''>	+	<StructureSection load='1zng' size='340' side='right'caption='[[1zng]], [[Resolution\|resolution]] 1.60Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1zng]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZNG OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1ZNG FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1zng]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZNG OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=1ZNG FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CD:CADMIUM+ION'>CD</scene>, <scene name='pdbligand=HE4:HEPTAN-1-OL'>HE4</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CD:CADMIUM+ION'>CD</scene>, <scene name='pdbligand=HE4:HEPTAN-1-OL'>HE4</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1znd\|1znd]], [[1zne\|1zne]], [[1znh\|1znh]], [[1znk\|1znk]], [[1znl\|1znl]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1znd\|1znd]], [[1zne\|1zne]], [[1znh\|1znh]], [[1znk\|1znk]], [[1znl\|1znl]]</div></td></tr>
	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">MUP1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 LK3 transgenic mice])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">MUP1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 LK3 transgenic mice])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1zng FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1zng OCA], [http://pdbe.org/1zng PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1zng RCSB], [http://www.ebi.ac.uk/pdbsum/1zng PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1zng ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=1zng FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1zng OCA], [http://pdbe.org/1zng PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1zng RCSB], [http://www.ebi.ac.uk/pdbsum/1zng PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1zng ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 34:		Line 34:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Large Structures]]
	[[Category: Lk3 transgenic mice]]		[[Category: Lk3 transgenic mice]]
	[[Category: Barratt, E]]		[[Category: Barratt, E]]

OCA at 09:11, 2 May 2018

OCA — Wed, 02 May 2018 09:11:55 GMT

←Older revision		Revision as of 09:11, 2 May 2018
Line 1:		Line 1:
		+
	==Strong Solute-Solute Dispersive Interactions in a Protein-Ligand Complex==		==Strong Solute-Solute Dispersive Interactions in a Protein-Ligand Complex==
	<StructureSection load='1zng' size='340' side='right' caption='[[1zng]], [[Resolution\|resolution]] 1.60Å' scene=''>		<StructureSection load='1zng' size='340' side='right' caption='[[1zng]], [[Resolution\|resolution]] 1.60Å' scene=''>
Line 6:		Line 7:
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1znd\|1znd]], [[1zne\|1zne]], [[1znh\|1znh]], [[1znk\|1znk]], [[1znl\|1znl]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1znd\|1znd]], [[1zne\|1zne]], [[1znh\|1znh]], [[1znk\|1znk]], [[1znl\|1znl]]</td></tr>
	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">MUP1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 LK3 transgenic mice])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">MUP1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 LK3 transgenic mice])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1zng FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1zng OCA], [http://pdbe.org/1zng PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1zng RCSB], [http://www.ebi.ac.uk/pdbsum/1zng PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1zng FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1zng OCA], [http://pdbe.org/1zng PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1zng RCSB], [http://www.ebi.ac.uk/pdbsum/1zng PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1zng ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 14:		Line 15:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/zn/1zng_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/zn/1zng_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1zng ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 09:22, 11 September 2015

OCA — Fri, 11 Sep 2015 09:22:34 GMT

←Older revision		Revision as of 09:22, 11 September 2015
Line 2:		Line 2:
	<StructureSection load='1zng' size='340' side='right' caption='[[1zng]], [[Resolution\|resolution]] 1.60Å' scene=''>		<StructureSection load='1zng' size='340' side='right' caption='[[1zng]], [[Resolution\|resolution]] 1.60Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1zng]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Mus_musculus Mus musculus~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZNG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ZNG FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1zng]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZNG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ZNG FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CD:CADMIUM+ION'>CD</scene>, <scene name='pdbligand=HE4:HEPTAN-1-OL'>HE4</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CD:CADMIUM+ION'>CD</scene>, <scene name='pdbligand=HE4:HEPTAN-1-OL'>HE4</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1znd\|1znd]], [[1zne\|1zne]], [[1znh\|1znh]], [[1znk\|1znk]], [[1znl\|1znl]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1znd\|1znd]], [[1zne\|1zne]], [[1znh\|1znh]], [[1znk\|1znk]], [[1znl\|1znl]]</td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">MUP1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 ~~Mus musculus~~])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">MUP1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 LK3 transgenic mice])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1zng FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1zng OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1zng RCSB], [http://www.ebi.ac.uk/pdbsum/1zng PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1zng FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1zng OCA], [http://pdbe.org/1zng PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1zng RCSB], [http://www.ebi.ac.uk/pdbsum/1zng PDBsum]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 28:		Line 28:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 1zng" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Mus musculus~~]]	+	[[Category: Lk3 transgenic mice]]
	[[Category: Barratt, E]]		[[Category: Barratt, E]]
	[[Category: Bingham, R J]]		[[Category: Bingham, R J]]

OCA at 14:26, 25 December 2014

OCA — Thu, 25 Dec 2014 14:26:33 GMT

←Older revision		Revision as of 14:26, 25 December 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1zng]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZNG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ZNG FirstGlance]. <br>		<table><tr><td colspan='2'>[[1zng]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZNG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ZNG FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CD:CADMIUM+ION'>CD</scene>, <scene name='pdbligand=HE4:HEPTAN-1-OL'>HE4</scene><br>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CD:CADMIUM+ION'>CD</scene>, <scene name='pdbligand=HE4:HEPTAN-1-OL'>HE4</scene></td></tr>
-	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1znd\|1znd]], [[1zne\|1zne]], [[1znh\|1znh]], [[1znk\|1znk]], [[1znl\|1znl]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1znd\|1znd]], [[1zne\|1zne]], [[1znh\|1znh]], [[1znk\|1znk]], [[1znl\|1znl]]</td></tr>
-	<tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">MUP1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 Mus musculus])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">MUP1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 Mus musculus])</td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1zng FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1zng OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1zng RCSB], [http://www.ebi.ac.uk/pdbsum/1zng PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1zng FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1zng OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1zng RCSB], [http://www.ebi.ac.uk/pdbsum/1zng PDBsum]</span></td></tr>
-	<table>	+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/MUP2_MOUSE MUP2_MOUSE]] Binds pheromones that are released from drying urine of males. These pheromones affect the sexual behavior of females.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 31:		Line 33:
	</StructureSection>		</StructureSection>
	[[Category: Mus musculus]]		[[Category: Mus musculus]]
-	[[Category: Barratt, E.]]	+	[[Category: Barratt, E]]
-	[[Category: Bingham, R J.]]	+	[[Category: Bingham, R J]]
-	[[Category: Homans, S W.]]	+	[[Category: Homans, S W]]
-	[[Category: Johnstone, S.]]	+	[[Category: Johnstone, S]]
-	[[Category: Laughton, C A.]]	+	[[Category: Laughton, C A]]
-	[[Category: Malham, R.]]	+	[[Category: Malham, R]]
-	[[Category: Phillips, S E.]]	+	[[Category: Phillips, S E]]
	[[Category: Beta-barrel]]		[[Category: Beta-barrel]]
	[[Category: Lipocalin]]		[[Category: Lipocalin]]
	[[Category: Transport protein]]		[[Category: Transport protein]]

OCA at 02:00, 30 September 2014

OCA — Tue, 30 Sep 2014 02:00:20 GMT

←Older revision		Revision as of 02:00, 30 September 2014
Line 1:		Line 1:
-	[[~~Image:~~1zng.~~png~~\|~~left~~\|200px]]	+	==Strong Solute-Solute Dispersive Interactions in a Protein-Ligand Complex==
		+	<StructureSection load='1zng' size='340' side='right' caption='[[1zng]], [[Resolution\|resolution]] 1.60Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[1zng]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZNG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ZNG FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CD:CADMIUM+ION'>CD</scene>, <scene name='pdbligand=HE4:HEPTAN-1-OL'>HE4</scene><br>
		+	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1znd\|1znd]], [[1zne\|1zne]], [[1znh\|1znh]], [[1znk\|1znk]], [[1znl\|1znl]]</td></tr>
		+	<tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">MUP1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 Mus musculus])</td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1zng FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1zng OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1zng RCSB], [http://www.ebi.ac.uk/pdbsum/1zng PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/zn/1zng_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	The contributions of solute-solute dispersion interactions to binding thermodynamics have generally been thought to be small, due to the surmised equality between solute-solvent dispersion interactions prior to the interaction versus solute-solute dispersion interactions following the interaction. The thermodynamics of binding of primary alcohols to the major urinary protein (MUP-I) indicate that this general assumption is not justified. The enthalpy of binding becomes more favorable with increasing chain length, whereas the entropy of binding becomes less favorable, both parameters showing a linear dependence. Despite the hydrophobicity of the interacting species, these data show that binding is not dominated by the classical hydrophobic effect, but can be attributed to favorable ligand-protein dispersion interactions.

-	~~{{STRUCTURE_1zng\| PDB=1zng \| SCENE= }}~~	+	Strong solute-solute dispersive interactions in a protein-ligand complex.,Malham R, Johnstone S, Bingham RJ, Barratt E, Phillips SE, Laughton CA, Homans SW J Am Chem Soc. 2005 Dec 7;127(48):17061-7. PMID:16316253<ref>PMID:16316253</ref>

-	~~===Strong Solute-Solute Dispersive Interactions in~~ a ~~Protein-Ligand Complex===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_16316253}}~~	+	== References ==
-		+	<references/>
-	~~==About this Structure==~~	+	__TOC__
-	~~[[1zng]] is a 1 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Mus_musculus Mus musculus]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=1ZNG OCA].~~	+	</StructureSection>
-		+
-	==~~Reference~~==	+
-	<~~ref group="xtra">PMID:016316253<~~/~~ref~~><~~references group="xtra"~~/>	+
	[[Category: Mus musculus]]		[[Category: Mus musculus]]
	[[Category: Barratt, E.]]		[[Category: Barratt, E.]]

OCA: Protected "1zng" [edit=sysop:move=sysop]

OCA — Sat, 05 Jan 2013 17:32:10 GMT

Protected "1zng" [edit=sysop:move=sysop]

←Older revision

Revision as of 17:32, 5 January 2013

OCA at 17:32, 5 January 2013

OCA — Sat, 05 Jan 2013 17:32:07 GMT

←Older revision		Revision as of 17:32, 5 January 2013
Line 1:		Line 1:
-	{{Seed}}
	[[Image:1zng.png\|left\|200px]]		[[Image:1zng.png\|left\|200px]]

-	<!--
-	The line below this paragraph, containing "STRUCTURE_1zng", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_1zng\| PDB=1zng \| SCENE= }}		{{STRUCTURE_1zng\| PDB=1zng \| SCENE= }}

	===Strong Solute-Solute Dispersive Interactions in a Protein-Ligand Complex===		===Strong Solute-Solute Dispersive Interactions in a Protein-Ligand Complex===

-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_16316253}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where 16316253 is the PubMed ID number.
-	-->
	{{ABSTRACT_PUBMED_16316253}}		{{ABSTRACT_PUBMED_16316253}}

	==About this Structure==		==About this Structure==
-	~~1ZNG~~ is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZNG OCA].	+	[[1zng]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZNG OCA].

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~16316253~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:016316253</ref><references group="xtra"/>
	[[Category: Mus musculus]]		[[Category: Mus musculus]]
	[[Category: Barratt, E.]]		[[Category: Barratt, E.]]
Line 34:		Line 22:
	[[Category: Beta-barrel]]		[[Category: Beta-barrel]]
	[[Category: Lipocalin]]		[[Category: Lipocalin]]
-		+	[[Category: Transport protein]]
-	~~''Page seeded by~~ [~~http~~:~~//oca.weizmann.ac.il/oca OCA~~ ] ~~on Tue Feb 17 18:40:36 2009''~~	+

OCA at 16:40, 17 February 2009

OCA — Tue, 17 Feb 2009 16:40:37 GMT

←Older revision		Revision as of 16:40, 17 February 2009
Line 20:		Line 20:

	==About this Structure==		==About this Structure==
-	1ZNG is a ~~[[Single protein]]~~ structure of sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZNG OCA].	+	1ZNG is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZNG OCA].

	==Reference==		==Reference==
-	~~Strong solute-solute dispersive interactions in a protein-ligand complex., Malham R, Johnstone S, Bingham RJ, Barratt E, Phillips SE, Laughton CA, Homans SW, J Am Chem Soc. 2005 Dec 7;127(48):17061-7.~~ PMID:~~[http:~~//~~www.ncbi.nlm.nih.gov/pubmed/16316253 16316253]~~	+	<ref group="xtra">PMID:16316253</ref><references group="xtra"/>
	[[Category: Mus musculus]]		[[Category: Mus musculus]]
-	[[Category: Single protein]]
	[[Category: Barratt, E.]]		[[Category: Barratt, E.]]
	[[Category: Bingham, R J.]]		[[Category: Bingham, R J.]]
Line 36:		Line 35:
	[[Category: Lipocalin]]		[[Category: Lipocalin]]

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue ~~Jul 29 02~~:41:~~10 2008~~''	+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 18:40:36 2009''

OCA at 23:41, 28 July 2008

OCA — Mon, 28 Jul 2008 23:41:20 GMT

←Older revision		Revision as of 23:41, 28 July 2008
Line 1:		Line 1:
-	[[Image:1zng.~~gif~~\|left\|200px]]	+	{{Seed}}
		+	[[Image:1zng.png\|left\|200px]]

	<!--		<!--
Line 9:		Line 10:
	{{STRUCTURE_1zng\| PDB=1zng \| SCENE= }}		{{STRUCTURE_1zng\| PDB=1zng \| SCENE= }}

-	~~'''~~Strong Solute-Solute Dispersive Interactions in a Protein-Ligand Complex~~'''~~	+	===Strong Solute-Solute Dispersive Interactions in a Protein-Ligand Complex===


-	~~==Overview==~~	+	<!--
-	The ~~contributions of solute-solute dispersion interactions to binding thermodynamics have generally been thought to be small~~, ~~due to~~ the ~~surmised equality between solute-solvent dispersion interactions prior~~ to the ~~interaction versus solute-solute dispersion interactions following the interaction. The thermodynamics of binding of primary alcohols to the major urinary protein~~ (~~MUP-I) indicate that this general assumption is not justified~~. ~~The enthalpy of binding becomes more favorable with increasing chain length, whereas the entropy of binding becomes less favorable, both parameters showing a linear dependence~~. ~~Despite the hydrophobicity of the interacting species~~, ~~these data show that binding~~ is ~~not dominated by~~ the ~~classical hydrophobic effect, but can be attributed to favorable ligand~~-~~protein dispersion interactions.~~	+	The line below this paragraph, {{ABSTRACT_PUBMED_16316253}}, adds the Publication Abstract to the page
		+	(as it appears on PubMed at http://www.pubmed.gov), where 16316253 is the PubMed ID number.
		+	-->
		+	{{ABSTRACT_PUBMED_16316253}}

	==About this Structure==		==About this Structure==
Line 31:		Line 35:
	[[Category: Beta-barrel]]		[[Category: Beta-barrel]]
	[[Category: Lipocalin]]		[[Category: Lipocalin]]
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on ~~Sat May 3 17~~:50:36 2008''	+
		+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 29 02:41:10 2008''