1zpg - Revision history

OCA at 08:12, 15 May 2024

OCA — Wed, 15 May 2024 08:12:12 GMT

←Older revision		Revision as of 08:12, 15 May 2024
Line 3:		Line 3:
	<StructureSection load='1zpg' size='340' side='right'caption='[[1zpg]], [[Resolution\|resolution]] 1.90Å' scene=''>		<StructureSection load='1zpg' size='340' side='right'caption='[[1zpg]], [[Resolution\|resolution]] 1.90Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1zpg]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Buffalo_rat Buffalo rat~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZPG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1ZPG FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1zpg]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZPG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1ZPG FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.9Å</td></tr>
-	<tr id='~~NonStdRes~~'><td class="sblockLbl"><b>[[~~Non-Standard_Residue~~\|~~NonStd Res~~:]]</b></td><td class="sblockDat"><scene name='pdbligand=BPE:(2S)-2-AMINO-3-[(3-AMINOPROPYL)SULFANYL]PROPAN-1-OL'>BPE</scene>~~</td></tr>~~	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BPE:(2S)-2-AMINO-3-[(3-AMINOPROPYL)SULFANYL]PROPAN-1-OL'>BPE</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr>
-	~~<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1zpe\|1zpe]]~~, ~~[[1tbj\|1tbj]], [[1ta1\|1ta1]], [[1tbh\|1tbh]], [[1tbl\|1tbl]]~~<~~/div></td></tr>~~	+
-	~~<tr id~~='~~gene'><td class~~=~~"sblockLbl"><b>[[Gene\|Gene~~:~~]]</b></td><td class="sblockDat">Arg1~~ (~~[https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10116 Buffalo rat]~~)~~</td></tr>~~	+
-	~~<tr id='activity~~'>~~<td class="sblockLbl"><b>Activity:~~</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Arginase Arginase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.3.1 3.5.3.1] </span></td></tr>	+
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1zpg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1zpg OCA], [https://pdbe.org/1zpg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1zpg RCSB], [https://www.ebi.ac.uk/pdbsum/1zpg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1zpg ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1zpg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1zpg OCA], [https://pdbe.org/1zpg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1zpg RCSB], [https://www.ebi.ac.uk/pdbsum/1zpg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1zpg ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/ARGI1_RAT ARGI1_RAT]
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 37:		Line 36:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Arginase]]
-	[[Category: Buffalo rat]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Ash~~, D E~~]]	+	[[Category: Rattus norvegicus]]
-	[[Category: Cama, E]]	+	[[Category: Ash DE]]
-	[[Category: Christianson~~, D W~~]]	+	[[Category: Cama E]]
-	[[Category: Colleluori~~, D M~~]]	+	[[Category: Christianson DW]]
-	[[Category: Compher, K]]	+	[[Category: Colleluori DM]]
-	[[Category: Cox~~, J D~~]]	+	[[Category: Compher K]]
-	[[Category: Emig~~, F A~~]]	+	[[Category: Cox JD]]
-	[[Category: Han, S]]	+	[[Category: Emig FA]]
-	[[Category: Jude, K]]	+	[[Category: Han S]]
-	[[Category: Reczkowski~~, R S~~]]	+	[[Category: Jude K]]
-	[[Category: Scolnick~~, L R~~]]	+	[[Category: Reczkowski RS]]
-	[[Category: Viola~~, R E]]~~	+	[[Category: Scolnick LR]]
-	~~[[Category: Chemically modified enzyme]]~~	+	[[Category: Viola RE]]
-	~~[[Category: Hydrolase~~]]	+

OCA at 08:14, 27 January 2021

OCA — Wed, 27 Jan 2021 08:14:31 GMT

←Older revision		Revision as of 08:14, 27 January 2021
Line 1:		Line 1:

	==Arginase I covalently modified with propylamine at Q19C==		==Arginase I covalently modified with propylamine at Q19C==
-	<StructureSection load='1zpg' size='340' side='right' caption='[[1zpg]], [[Resolution\|resolution]] 1.90Å' scene=''>	+	<StructureSection load='1zpg' size='340' side='right'caption='[[1zpg]], [[Resolution\|resolution]] 1.90Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1zpg]] is a 3 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Buffalo_rat Buffalo rat]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZPG OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1ZPG FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1zpg]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Buffalo_rat Buffalo rat]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZPG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1ZPG FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr>
	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=BPE:(2S)-2-AMINO-3-[(3-AMINOPROPYL)SULFANYL]PROPAN-1-OL'>BPE</scene></td></tr>		<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=BPE:(2S)-2-AMINO-3-[(3-AMINOPROPYL)SULFANYL]PROPAN-1-OL'>BPE</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1zpe\|1zpe]], [[1tbj\|1tbj]], [[1ta1\|1ta1]], [[1tbh\|1tbh]], [[1tbl\|1tbl]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1zpe\|1zpe]], [[1tbj\|1tbj]], [[1ta1\|1ta1]], [[1tbh\|1tbh]], [[1tbl\|1tbl]]</div></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">Arg1 ([~~http~~://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10116 Buffalo rat])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">Arg1 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10116 Buffalo rat])</td></tr>
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://en.wikipedia.org/wiki/Arginase Arginase], with EC number [~~http~~://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.3.1 3.5.3.1] </span></td></tr>	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Arginase Arginase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.3.1 3.5.3.1] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1zpg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1zpg OCA], [~~http~~://pdbe.org/1zpg PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=1zpg RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/1zpg PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=1zpg ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1zpg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1zpg OCA], [https://pdbe.org/1zpg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1zpg RCSB], [https://www.ebi.ac.uk/pdbsum/1zpg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1zpg ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 30:		Line 30:
	</div>		</div>
	<div class="pdbe-citations 1zpg" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 1zpg" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[Arginase 3D structures\|Arginase 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
Line 36:		Line 39:
	[[Category: Arginase]]		[[Category: Arginase]]
	[[Category: Buffalo rat]]		[[Category: Buffalo rat]]
		+	[[Category: Large Structures]]
	[[Category: Ash, D E]]		[[Category: Ash, D E]]
	[[Category: Cama, E]]		[[Category: Cama, E]]

OCA at 08:55, 2 May 2018

OCA — Wed, 02 May 2018 08:55:55 GMT

←Older revision		Revision as of 08:55, 2 May 2018
Line 1:		Line 1:
		+
	==Arginase I covalently modified with propylamine at Q19C==		==Arginase I covalently modified with propylamine at Q19C==
	<StructureSection load='1zpg' size='340' side='right' caption='[[1zpg]], [[Resolution\|resolution]] 1.90Å' scene=''>		<StructureSection load='1zpg' size='340' side='right' caption='[[1zpg]], [[Resolution\|resolution]] 1.90Å' scene=''>
Line 8:		Line 9:
	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">Arg1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10116 Buffalo rat])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">Arg1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10116 Buffalo rat])</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Arginase Arginase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.3.1 3.5.3.1] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Arginase Arginase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.3.1 3.5.3.1] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1zpg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1zpg OCA], [http://pdbe.org/1zpg PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1zpg RCSB], [http://www.ebi.ac.uk/pdbsum/1zpg PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1zpg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1zpg OCA], [http://pdbe.org/1zpg PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1zpg RCSB], [http://www.ebi.ac.uk/pdbsum/1zpg PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1zpg ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 14:		Line 15:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/zp/1zpg_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/zp/1zpg_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
Line 29:		Line 30:
	</div>		</div>
	<div class="pdbe-citations 1zpg" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 1zpg" style="background-color:#fffaf0;"></div>
-
-	==See Also==
-	*[[Arginase\|Arginase]]
	== References ==		== References ==
	<references/>		<references/>

OCA at 04:29, 10 February 2016

OCA — Wed, 10 Feb 2016 04:29:10 GMT

←Older revision		Revision as of 04:29, 10 February 2016
Line 18:		Line 18:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1zpg ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 05:23, 11 September 2015

OCA — Fri, 11 Sep 2015 05:23:14 GMT

←Older revision		Revision as of 05:23, 11 September 2015
Line 2:		Line 2:
	<StructureSection load='1zpg' size='340' side='right' caption='[[1zpg]], [[Resolution\|resolution]] 1.90Å' scene=''>		<StructureSection load='1zpg' size='340' side='right' caption='[[1zpg]], [[Resolution\|resolution]] 1.90Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1zpg]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Rattus_norvegicus Rattus norvegicus~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZPG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ZPG FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1zpg]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Buffalo_rat Buffalo rat]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZPG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ZPG FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr>
	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=BPE:(2S)-2-AMINO-3-[(3-AMINOPROPYL)SULFANYL]PROPAN-1-OL'>BPE</scene></td></tr>		<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=BPE:(2S)-2-AMINO-3-[(3-AMINOPROPYL)SULFANYL]PROPAN-1-OL'>BPE</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1zpe\|1zpe]], [[1tbj\|1tbj]], [[1ta1\|1ta1]], [[1tbh\|1tbh]], [[1tbl\|1tbl]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1zpe\|1zpe]], [[1tbj\|1tbj]], [[1ta1\|1ta1]], [[1tbh\|1tbh]], [[1tbl\|1tbl]]</td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">Arg1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10116 ~~Rattus norvegicus~~])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">Arg1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10116 Buffalo rat])</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Arginase Arginase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.3.1 3.5.3.1] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Arginase Arginase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.3.1 3.5.3.1] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1zpg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1zpg OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1zpg RCSB], [http://www.ebi.ac.uk/pdbsum/1zpg PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1zpg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1zpg OCA], [http://pdbe.org/1zpg PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1zpg RCSB], [http://www.ebi.ac.uk/pdbsum/1zpg PDBsum]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 28:		Line 28:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 1zpg" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
Line 36:		Line 37:
	</StructureSection>		</StructureSection>
	[[Category: Arginase]]		[[Category: Arginase]]
-	[[Category: ~~Rattus norvegicus~~]]	+	[[Category: Buffalo rat]]
	[[Category: Ash, D E]]		[[Category: Ash, D E]]
	[[Category: Cama, E]]		[[Category: Cama, E]]

OCA at 10:08, 8 January 2015

OCA — Thu, 08 Jan 2015 10:08:27 GMT

←Older revision		Revision as of 10:08, 8 January 2015
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1zpg]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZPG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ZPG FirstGlance]. <br>		<table><tr><td colspan='2'>[[1zpg]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZPG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ZPG FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene><br>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr>
-	<tr><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=BPE:(2S)-2-AMINO-3-[(3-AMINOPROPYL)SULFANYL]PROPAN-1-OL'>BPE</scene></td></tr>	+	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=BPE:(2S)-2-AMINO-3-[(3-AMINOPROPYL)SULFANYL]PROPAN-1-OL'>BPE</scene></td></tr>
-	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1zpe\|1zpe]], [[1tbj\|1tbj]], [[1ta1\|1ta1]], [[1tbh\|1tbh]], [[1tbl\|1tbl]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1zpe\|1zpe]], [[1tbj\|1tbj]], [[1ta1\|1ta1]], [[1tbh\|1tbh]], [[1tbl\|1tbl]]</td></tr>
-	<tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">Arg1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10116 Rattus norvegicus])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">Arg1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10116 Rattus norvegicus])</td></tr>
-	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Arginase Arginase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.3.1 3.5.3.1] </span></td></tr>	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Arginase Arginase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.3.1 3.5.3.1] </span></td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1zpg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1zpg OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1zpg RCSB], [http://www.ebi.ac.uk/pdbsum/1zpg PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1zpg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1zpg OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1zpg RCSB], [http://www.ebi.ac.uk/pdbsum/1zpg PDBsum]</span></td></tr>
-	<table>	+	</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 37:		Line 37:
	[[Category: Arginase]]		[[Category: Arginase]]
	[[Category: Rattus norvegicus]]		[[Category: Rattus norvegicus]]
-	[[Category: Ash, D E.]]	+	[[Category: Ash, D E]]
-	[[Category: Cama, E.]]	+	[[Category: Cama, E]]
-	[[Category: Christianson, D W.]]	+	[[Category: Christianson, D W]]
-	[[Category: Colleluori, D M.]]	+	[[Category: Colleluori, D M]]
-	[[Category: Compher, K.]]	+	[[Category: Compher, K]]
-	[[Category: Cox, J D.]]	+	[[Category: Cox, J D]]
-	[[Category: Emig, F A.]]	+	[[Category: Emig, F A]]
-	[[Category: Han, S.]]	+	[[Category: Han, S]]
-	[[Category: Jude, K.]]	+	[[Category: Jude, K]]
-	[[Category: Reczkowski, R S.]]	+	[[Category: Reczkowski, R S]]
-	[[Category: Scolnick, L R.]]	+	[[Category: Scolnick, L R]]
-	[[Category: Viola, R E.]]	+	[[Category: Viola, R E]]
	[[Category: Chemically modified enzyme]]		[[Category: Chemically modified enzyme]]
	[[Category: Hydrolase]]		[[Category: Hydrolase]]

OCA at 00:53, 30 September 2014

OCA — Tue, 30 Sep 2014 00:53:06 GMT

←Older revision		Revision as of 00:53, 30 September 2014
Line 1:		Line 1:
-	[[~~Image:~~1zpg.~~png~~\|~~left~~\|200px]]	+	==Arginase I covalently modified with propylamine at Q19C==
		+	<StructureSection load='1zpg' size='340' side='right' caption='[[1zpg]], [[Resolution\|resolution]] 1.90Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[1zpg]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZPG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ZPG FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene><br>
		+	<tr><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=BPE:(2S)-2-AMINO-3-[(3-AMINOPROPYL)SULFANYL]PROPAN-1-OL'>BPE</scene></td></tr>
		+	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1zpe\|1zpe]], [[1tbj\|1tbj]], [[1ta1\|1ta1]], [[1tbh\|1tbh]], [[1tbl\|1tbl]]</td></tr>
		+	<tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">Arg1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10116 Rattus norvegicus])</td></tr>
		+	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Arginase Arginase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.3.1 3.5.3.1] </span></td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1zpg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1zpg OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1zpg RCSB], [http://www.ebi.ac.uk/pdbsum/1zpg PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/zp/1zpg_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Rat liver arginase (arginase I) is potently inactivated by diethyl pyrocarbonate, with a second-order rate constant of 113M(-1)s(-1) for the inactivation process at pH 7.0, 25 degrees C. Partial protection from inactivation is provided by the product of the reaction, l-ornithine, while nearly complete protection is afforded by the inhibitor pair, l-ornithine and borate. The role of H141 has been probed by mutagenesis, chemical modulation, and X-ray diffraction. The hyper-reactivity of H141 towards diethyl pyrocarbonate can be explained by its proximity to E277. A proton shuttling role for H141 is supported by its conformational mobility observed among the known arginase structures. H141 is proposed to serve as an acid/base catalyst, deprotonating the metal-bridging water molecule to generate the metal-bridging hydroxide nucleophile, and by protonating the amino group of the product to facilitate its departure.

-	~~{{STRUCTURE_1zpg\| PDB=1zpg \| SCENE= }}~~	+	Probing the role of the hyper-reactive histidine residue of arginase.,Colleluori DM, Reczkowski RS, Emig FA, Cama E, Cox JD, Scolnick LR, Compher K, Jude K, Han S, Viola RE, Christianson DW, Ash DE Arch Biochem Biophys. 2005 Dec 1;444(1):15-26. Epub 2005 Oct 13. PMID:16266687<ref>PMID:16266687</ref>

-	~~===Arginase I covalently modified with propylamine at Q19C===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>

-	~~{{ABSTRACT_PUBMED_16266687}}~~	+	==See Also==
-		+	*[[Arginase\|Arginase]]
-	==~~About this Structure~~==	+	== References ==
-	[[~~1zpg~~]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZPG OCA].	+	<references/>
-		+	__TOC__
-	==~~Reference~~==	+	</StructureSection>
-	<~~ref group="xtra">PMID:016266687<~~/~~ref~~><~~references group="xtra"~~/>	+
	[[Category: Arginase]]		[[Category: Arginase]]
	[[Category: Rattus norvegicus]]		[[Category: Rattus norvegicus]]

OCA: Protected "1zpg" [edit=sysop:move=sysop]

OCA — Sat, 05 Jan 2013 17:12:13 GMT

Protected "1zpg" [edit=sysop:move=sysop]

←Older revision

Revision as of 17:12, 5 January 2013

OCA at 17:12, 5 January 2013

OCA — Sat, 05 Jan 2013 17:12:10 GMT

←Older revision		Revision as of 17:12, 5 January 2013
Line 1:		Line 1:
-	{{Seed}}
	[[Image:1zpg.png\|left\|200px]]		[[Image:1zpg.png\|left\|200px]]

-	<!--
-	The line below this paragraph, containing "STRUCTURE_1zpg", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_1zpg\| PDB=1zpg \| SCENE= }}		{{STRUCTURE_1zpg\| PDB=1zpg \| SCENE= }}

	===Arginase I covalently modified with propylamine at Q19C===		===Arginase I covalently modified with propylamine at Q19C===

-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_16266687}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where 16266687 is the PubMed ID number.
-	-->
	{{ABSTRACT_PUBMED_16266687}}		{{ABSTRACT_PUBMED_16266687}}

	==About this Structure==		==About this Structure==
-	~~1ZPG~~ is a 3 ~~chains~~ structure ~~of sequences~~ from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZPG OCA].	+	[[1zpg]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZPG OCA].

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~16266687~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:016266687</ref><references group="xtra"/>
	[[Category: Arginase]]		[[Category: Arginase]]
	[[Category: Rattus norvegicus]]		[[Category: Rattus norvegicus]]
Line 39:		Line 27:
	[[Category: Viola, R E.]]		[[Category: Viola, R E.]]
	[[Category: Chemically modified enzyme]]		[[Category: Chemically modified enzyme]]
-		+	[[Category: Hydrolase]]
-	~~''Page seeded by~~ [~~http~~:~~//oca.weizmann.ac.il/oca OCA~~ ] ~~on Tue Feb 17 15:26:18 2009''~~	+

OCA at 13:26, 17 February 2009

OCA — Tue, 17 Feb 2009 13:26:19 GMT

←Older revision		Revision as of 13:26, 17 February 2009
Line 20:		Line 20:

	==About this Structure==		==About this Structure==
-	1ZPG is a ~~[[Single protein]]~~ structure of ~~sequence~~ from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZPG OCA].	+	1ZPG is a 3 chains structure of sequences from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZPG OCA].

	==Reference==		==Reference==
-	Probing the role of the hyper-reactive histidine residue of arginase., Colleluori DM, Reczkowski RS, Emig FA, Cama E, Cox JD, Scolnick LR, Compher K, Jude K, Han S, Viola RE, Christianson DW, Ash DE, Arch Biochem Biophys. 2005 Dec 1;444(1):15-26. Epub 2005 Oct 13. PMID:~~[http:~~//~~www.ncbi.nlm.nih.gov/pubmed/16266687 16266687]~~	+	<ref group="xtra">PMID:16266687</ref><references group="xtra"/>
	[[Category: Arginase]]		[[Category: Arginase]]
	[[Category: Rattus norvegicus]]		[[Category: Rattus norvegicus]]
-	[[Category: Single protein]]
	[[Category: Ash, D E.]]		[[Category: Ash, D E.]]
	[[Category: Cama, E.]]		[[Category: Cama, E.]]
Line 41:		Line 40:
	[[Category: Chemically modified enzyme]]		[[Category: Chemically modified enzyme]]

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on ~~Mon Jul 28 21~~:04:~~59 2008~~''	+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 15:26:18 2009''