1zpq - Revision history

OCA at 09:06, 14 February 2024

OCA — Wed, 14 Feb 2024 09:06:26 GMT

←Older revision		Revision as of 09:06, 14 February 2024
Line 3:		Line 3:
	<StructureSection load='1zpq' size='340' side='right'caption='[[1zpq]], [[Resolution\|resolution]] 2.80Å' scene=''>		<StructureSection load='1zpq' size='340' side='right'caption='[[1zpq]], [[Resolution\|resolution]] 2.80Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1zpq]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Bacteriophage_lambda Bacteriophage lambda~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZPQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1ZPQ FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1zpq]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_virus_Lambda Escherichia virus Lambda]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZPQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1ZPQ FirstGlance]. <br>
-	</td></tr><tr id='~~gene~~'><td class="sblockLbl"><b>[[~~Gene~~\|~~Gene~~:]]</b></td><td class="sblockDat">~~CII (~~[~~https://www~~.~~ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info~~&~~srchmode=5&id=10710 Bacteriophage lambda])~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.8Å</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1zpq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1zpq OCA], [https://pdbe.org/1zpq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1zpq RCSB], [https://www.ebi.ac.uk/pdbsum/1zpq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1zpq ProSAT], [https://www.topsan.org/Proteins/MCSG/1zpq TOPSAN]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1zpq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1zpq OCA], [https://pdbe.org/1zpq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1zpq RCSB], [https://www.ebi.ac.uk/pdbsum/1zpq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1zpq ProSAT], [https://www.topsan.org/Proteins/MCSG/1zpq TOPSAN]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[https://www.uniprot.org/uniprot/RPC2_LAMBD RPC2_LAMBD]] This protein and protein CIII form a complex that is involved in the initiation of lysogeny. The complex binds at either of the cy regulatory sites preceding the CI repressor protein and integrase coding regions and induces transcription of these genes.	+	[https://www.uniprot.org/uniprot/RPC2_LAMBD RPC2_LAMBD] This protein and protein CIII form a complex that is involved in the initiation of lysogeny. The complex binds at either of the cy regulatory sites preceding the CI repressor protein and integrase coding regions and induces transcription of these genes.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 19:		Line 19:
	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1zpq ConSurf].		</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1zpq ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
-	<div style="background-color:#fffaf0;">
-	== Publication Abstract from PubMed ==
-	The tetrameric cII protein from bacteriophage lambda activates transcription from the phage promoters P(RE), P(I), and P(AQ) by binding to two direct repeats that flank the promoter -35 element. Here, we present the X-ray crystal structure of cII alone (2.8 A resolution) and in complex with its DNA operator from P(RE) (1.7 A resolution). The structures provide a basis for modeling of the activation complex with the RNA polymerase holoenzyme, and point to the key role for the RNA polymerase alpha subunit C-terminal domain (alphaCTD) in cII-dependent activation, which forms a bridge of protein/protein interactions between cII and the RNA polymerase sigma subunit. The model makes specific predictions for protein/protein interactions between cII and alphaCTD, and between alphaCTD and sigma, which are supported by previous genetic studies.
-
-	Crystal structure of bacteriophage lambda cII and its DNA complex.,Jain D, Kim Y, Maxwell KL, Beasley S, Zhang R, Gussin GN, Edwards AM, Darst SA Mol Cell. 2005 Jul 22;19(2):259-69. PMID:16039594<ref>PMID:16039594</ref>
-
-	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	</div>
-	<div class="pdbe-citations 1zpq" style="background-color:#fffaf0;"></div>
-	== References ==
-	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Bacteriophage lambda~~]]	+	[[Category: Escherichia virus Lambda]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Beasley, S]]	+	[[Category: Beasley S]]
-	[[Category: Darst~~, S A~~]]	+	[[Category: Darst SA]]
-	[[Category: Edwards~~, A M~~]]	+	[[Category: Edwards AM]]
-	[[Category: Gussin~~, G N~~]]	+	[[Category: Gussin GN]]
-	[[Category: Jain, D]]	+	[[Category: Jain D]]
-	[[Category: Joachimiak, A]]	+	[[Category: Joachimiak A]]
-	[[Category: Kim, Y]]	+	[[Category: Kim Y]]
-	~~[[Category: Structural genomic~~]]	+	[[Category: Maxwell KL]]
-	[[Category: Maxwell~~, K L]]~~	+
-	~~[[Category: Helix-turn-helix]]~~	+
-	~~[[Category: Mcsg]]~~	+
-	~~[[Category: PSI, Protein structure initiative]]~~	+
-	~~[[Category: Transcription activation]]~~	+
-	~~[[Category: Transcription activator~~]]	+

OCA at 08:14, 27 January 2021

OCA — Wed, 27 Jan 2021 08:14:36 GMT

←Older revision		Revision as of 08:14, 27 January 2021
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	==STRUCTURE OF BACTERIOPHAGE LAMBDA CII protein==		==STRUCTURE OF BACTERIOPHAGE LAMBDA CII protein==
-	<StructureSection load='1zpq' size='340' side='right' caption='[[1zpq]], [[Resolution\|resolution]] 2.80Å' scene=''>	+	<StructureSection load='1zpq' size='340' side='right'caption='[[1zpq]], [[Resolution\|resolution]] 2.80Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1zpq]] is a 4 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Bacteriophage_lambda Bacteriophage lambda]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZPQ OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1ZPQ FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1zpq]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacteriophage_lambda Bacteriophage lambda]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZPQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1ZPQ FirstGlance]. <br>
-	</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">CII ([~~http~~://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10710 Bacteriophage lambda])</td></tr>	+	</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">CII ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10710 Bacteriophage lambda])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1zpq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1zpq OCA], [~~http~~://pdbe.org/1zpq PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=1zpq RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/1zpq PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=1zpq ProSAT], [~~http~~://www.topsan.org/Proteins/MCSG/1zpq TOPSAN]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1zpq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1zpq OCA], [https://pdbe.org/1zpq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1zpq RCSB], [https://www.ebi.ac.uk/pdbsum/1zpq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1zpq ProSAT], [https://www.topsan.org/Proteins/MCSG/1zpq TOPSAN]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[~~http~~://www.uniprot.org/uniprot/RPC2_LAMBD RPC2_LAMBD]] This protein and protein CIII form a complex that is involved in the initiation of lysogeny. The complex binds at either of the cy regulatory sites preceding the CI repressor protein and integrase coding regions and induces transcription of these genes.	+	[[https://www.uniprot.org/uniprot/RPC2_LAMBD RPC2_LAMBD]] This protein and protein CIII form a complex that is involved in the initiation of lysogeny. The complex binds at either of the cy regulatory sites preceding the CI repressor protein and integrase coding regions and induces transcription of these genes.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 33:		Line 33:
	</StructureSection>		</StructureSection>
	[[Category: Bacteriophage lambda]]		[[Category: Bacteriophage lambda]]
		+	[[Category: Large Structures]]
	[[Category: Beasley, S]]		[[Category: Beasley, S]]
	[[Category: Darst, S A]]		[[Category: Darst, S A]]

OCA at 09:28, 2 May 2018

OCA — Wed, 02 May 2018 09:28:22 GMT

←Older revision		Revision as of 09:28, 2 May 2018
Line 1:		Line 1:
		+
	==STRUCTURE OF BACTERIOPHAGE LAMBDA CII protein==		==STRUCTURE OF BACTERIOPHAGE LAMBDA CII protein==
	<StructureSection load='1zpq' size='340' side='right' caption='[[1zpq]], [[Resolution\|resolution]] 2.80Å' scene=''>		<StructureSection load='1zpq' size='340' side='right' caption='[[1zpq]], [[Resolution\|resolution]] 2.80Å' scene=''>
Line 4:		Line 5:
	<table><tr><td colspan='2'>[[1zpq]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacteriophage_lambda Bacteriophage lambda]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZPQ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ZPQ FirstGlance]. <br>		<table><tr><td colspan='2'>[[1zpq]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacteriophage_lambda Bacteriophage lambda]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZPQ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ZPQ FirstGlance]. <br>
	</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">CII ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10710 Bacteriophage lambda])</td></tr>		</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">CII ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10710 Bacteriophage lambda])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1zpq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1zpq OCA], [http://pdbe.org/1zpq PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1zpq RCSB], [http://www.ebi.ac.uk/pdbsum/1zpq PDBsum], [http://www.topsan.org/Proteins/MCSG/1zpq TOPSAN]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1zpq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1zpq OCA], [http://pdbe.org/1zpq PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1zpq RCSB], [http://www.ebi.ac.uk/pdbsum/1zpq PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1zpq ProSAT], [http://www.topsan.org/Proteins/MCSG/1zpq TOPSAN]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 12:		Line 13:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/zp/1zpq_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/zp/1zpq_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>

OCA at 21:52, 7 February 2016

OCA — Sun, 07 Feb 2016 21:52:43 GMT

←Older revision		Revision as of 21:52, 7 February 2016
Line 16:		Line 16:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1zpq ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 05:16, 10 September 2015

OCA — Thu, 10 Sep 2015 05:16:54 GMT

←Older revision		Revision as of 05:16, 10 September 2015
Line 2:		Line 2:
	<StructureSection load='1zpq' size='340' side='right' caption='[[1zpq]], [[Resolution\|resolution]] 2.80Å' scene=''>		<StructureSection load='1zpq' size='340' side='right' caption='[[1zpq]], [[Resolution\|resolution]] 2.80Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1zpq]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Enterobacteria_phage_lambda Enterobacteria phage~~ lambda]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZPQ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ZPQ FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1zpq]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacteriophage_lambda Bacteriophage lambda]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZPQ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ZPQ FirstGlance]. <br>
-	</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">CII ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10710 ~~Enterobacteria phage~~ lambda])</td></tr>	+	</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">CII ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10710 Bacteriophage lambda])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1zpq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1zpq OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1zpq RCSB], [http://www.ebi.ac.uk/pdbsum/1zpq PDBsum], [http://www.topsan.org/Proteins/MCSG/1zpq TOPSAN]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1zpq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1zpq OCA], [http://pdbe.org/1zpq PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1zpq RCSB], [http://www.ebi.ac.uk/pdbsum/1zpq PDBsum], [http://www.topsan.org/Proteins/MCSG/1zpq TOPSAN]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 26:		Line 26:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 1zpq" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Enterobacteria phage~~ lambda]]	+	[[Category: Bacteriophage lambda]]
	[[Category: Beasley, S]]		[[Category: Beasley, S]]
	[[Category: Darst, S A]]		[[Category: Darst, S A]]

OCA at 18:28, 24 December 2014

OCA — Wed, 24 Dec 2014 18:28:51 GMT

←Older revision		Revision as of 18:28, 24 December 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1zpq]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Enterobacteria_phage_lambda Enterobacteria phage lambda]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZPQ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ZPQ FirstGlance]. <br>		<table><tr><td colspan='2'>[[1zpq]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Enterobacteria_phage_lambda Enterobacteria phage lambda]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZPQ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ZPQ FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">CII ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10710 Enterobacteria phage lambda])</td></tr>	+	</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">CII ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10710 Enterobacteria phage lambda])</td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1zpq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1zpq OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1zpq RCSB], [http://www.ebi.ac.uk/pdbsum/1zpq PDBsum], [http://www.topsan.org/Proteins/MCSG/1zpq TOPSAN]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1zpq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1zpq OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1zpq RCSB], [http://www.ebi.ac.uk/pdbsum/1zpq PDBsum], [http://www.topsan.org/Proteins/MCSG/1zpq TOPSAN]</span></td></tr>
-	<table>	+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/RPC2_LAMBD RPC2_LAMBD]] This protein and protein CIII form a complex that is involved in the initiation of lysogeny. The complex binds at either of the cy regulatory sites preceding the CI repressor protein and integrase coding regions and induces transcription of these genes.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 29:		Line 31:
	</StructureSection>		</StructureSection>
	[[Category: Enterobacteria phage lambda]]		[[Category: Enterobacteria phage lambda]]
-	[[Category: Beasley, S.]]	+	[[Category: Beasley, S]]
-	[[Category: Darst, S A.]]	+	[[Category: Darst, S A]]
-	[[Category: Edwards, A M.]]	+	[[Category: Edwards, A M]]
-	[[Category: Gussin, G N.]]	+	[[Category: Gussin, G N]]
-	[[Category: Jain, D.]]	+	[[Category: Jain, D]]
-	[[Category: Joachimiak, A.]]	+	[[Category: Joachimiak, A]]
-	[[Category: Kim, Y.]]	+	[[Category: Kim, Y]]
-	[[Category: ~~MCSG, Midwest Center for~~ Structural ~~Genomics.~~]]	+	[[Category: Structural genomic]]
-	[[Category: Maxwell, K L.]]	+	[[Category: Maxwell, K L]]
	[[Category: Helix-turn-helix]]		[[Category: Helix-turn-helix]]
	[[Category: Mcsg]]		[[Category: Mcsg]]
-	[[Category: ~~Midwest center for structural genomic]]~~	+	[[Category: PSI, Protein structure initiative]]
-	~~[[Category:~~ Protein structure initiative]]	+
-	~~[[Category: Psi]]~~	+
-	~~[[Category: Structural genomic~~]]	+
	[[Category: Transcription activation]]		[[Category: Transcription activation]]
	[[Category: Transcription activator]]		[[Category: Transcription activator]]

OCA at 09:10, 3 October 2014

OCA — Fri, 03 Oct 2014 09:10:23 GMT

←Older revision		Revision as of 09:10, 3 October 2014
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-	~~{{STRUCTURE_1zpq\| PDB~~=1zpq \| ~~SCENE~~= }}	+	==STRUCTURE OF BACTERIOPHAGE LAMBDA CII protein==
-	===~~STRUCTURE OF BACTERIOPHAGE LAMBDA~~ CII protein===	+	<StructureSection load='1zpq' size='340' side='right' caption='[[1zpq]], [[Resolution\|resolution]] 2.80Å' scene=''>
-	~~{{ABSTRACT_PUBMED_16039594}}~~	+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[1zpq]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Enterobacteria_phage_lambda Enterobacteria phage lambda]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZPQ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ZPQ FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">CII ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10710 Enterobacteria phage lambda])</td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1zpq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1zpq OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1zpq RCSB], [http://www.ebi.ac.uk/pdbsum/1zpq PDBsum], [http://www.topsan.org/Proteins/MCSG/1zpq TOPSAN]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/zp/1zpq_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	The tetrameric cII protein from bacteriophage lambda activates transcription from the phage promoters P(RE), P(I), and P(AQ) by binding to two direct repeats that flank the promoter -35 element. Here, we present the X-ray crystal structure of cII alone (2.8 A resolution) and in complex with its DNA operator from P(RE) (1.7 A resolution). The structures provide a basis for modeling of the activation complex with the RNA polymerase holoenzyme, and point to the key role for the RNA polymerase alpha subunit C-terminal domain (alphaCTD) in cII-dependent activation, which forms a bridge of protein/protein interactions between cII and the RNA polymerase sigma subunit. The model makes specific predictions for protein/protein interactions between cII and alphaCTD, and between alphaCTD and sigma, which are supported by previous genetic studies.

-	~~==Function==~~	+	Crystal structure of bacteriophage lambda cII and its DNA complex.,Jain D, Kim Y, Maxwell KL, Beasley S, Zhang R, Gussin GN, Edwards AM, Darst SA Mol Cell. 2005 Jul 22;19(2):259-69. PMID:16039594<ref>PMID:16039594</ref>
-	~~[[http://www.uniprot.org/uniprot/RPC2_LAMBD RPC2_LAMBD]] This protein~~ and ~~protein CIII form a~~ complex ~~that is involved in the initiation of lysogeny~~. ~~The complex binds at either of the cy regulatory sites preceding the CI repressor protein and integrase coding regions and induces transcription of these genes~~.	+

-	~~==About this Structure==~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	~~[[1zpq]] is~~ a ~~4 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Enterobacteria_phage_lambda Enterobacteria phage lambda]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=1ZPQ OCA].~~	+	</div>
-		+	== References ==
-	==~~Reference~~==	+	<references/>
-	~~<ref group="xtra">PMID:016039594</ref>~~<references ~~group="xtra"~~/><~~references~~/>	+	__TOC__
		+	</StructureSection>
	[[Category: Enterobacteria phage lambda]]		[[Category: Enterobacteria phage lambda]]
	[[Category: Beasley, S.]]		[[Category: Beasley, S.]]

OCA at 08:52, 23 April 2014

OCA — Wed, 23 Apr 2014 08:52:34 GMT

←Older revision		Revision as of 08:52, 23 April 2014
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-	[[Image:1zpq.png\|left\|200px]]
-
-	<!--
-	The line below this paragraph, containing "STRUCTURE_1zpq", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_1zpq\| PDB=1zpq \| SCENE= }}		{{STRUCTURE_1zpq\| PDB=1zpq \| SCENE= }}
-
	===STRUCTURE OF BACTERIOPHAGE LAMBDA CII protein===		===STRUCTURE OF BACTERIOPHAGE LAMBDA CII protein===
		+	{{ABSTRACT_PUBMED_16039594}}

-		+	==Function==
-	~~<!--~~	+	[[http://www.uniprot.org/uniprot/RPC2_LAMBD RPC2_LAMBD]] This protein and protein CIII form a complex that is involved in the initiation of lysogeny. The complex binds at either of the cy regulatory sites preceding the CI repressor protein and integrase coding regions and induces transcription of these genes.
-	~~The line below this paragraph, {{ABSTRACT_PUBMED_16039594}}, adds the Publication Abstract to the page~~	+
-	~~(as it appears on PubMed at~~ http://www.~~pubmed~~.~~gov), where 16039594~~ is the ~~PubMed ID number~~.	+
-	~~-->~~	+
-	~~{{ABSTRACT_PUBMED_16039594}}~~	+

	==About this Structure==		==About this Structure==
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	==Reference==		==Reference==
-	<ref group="xtra">PMID:016039594</ref><references group="xtra"/>	+	<ref group="xtra">PMID:016039594</ref><references group="xtra"/><references/>
	[[Category: Enterobacteria phage lambda]]		[[Category: Enterobacteria phage lambda]]
	[[Category: Beasley, S.]]		[[Category: Beasley, S.]]

OCA: Protected "1zpq" [edit=sysop:move=sysop]

OCA — Wed, 05 Oct 2011 05:54:20 GMT

Protected "1zpq" [edit=sysop:move=sysop]

←Older revision

Revision as of 05:54, 5 October 2011

OCA at 05:54, 5 October 2011

OCA — Wed, 05 Oct 2011 05:54:18 GMT

←Older revision		Revision as of 05:54, 5 October 2011
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-	{{Seed}}
	[[Image:1zpq.png\|left\|200px]]		[[Image:1zpq.png\|left\|200px]]

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	==About this Structure==		==About this Structure==
-	~~1ZPQ~~ is a 4 ~~chains~~ structure ~~of sequences~~ from [http://en.wikipedia.org/wiki/Enterobacteria_phage_lambda Enterobacteria phage lambda]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZPQ OCA].	+	[[1zpq]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Enterobacteria_phage_lambda Enterobacteria phage lambda]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZPQ OCA].

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~16039594~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:016039594</ref><references group="xtra"/>
	[[Category: Enterobacteria phage lambda]]		[[Category: Enterobacteria phage lambda]]
	[[Category: Beasley, S.]]		[[Category: Beasley, S.]]
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	[[Category: Gussin, G N.]]		[[Category: Gussin, G N.]]
	[[Category: Jain, D.]]		[[Category: Jain, D.]]
		+	[[Category: Joachimiak, A.]]
	[[Category: Kim, Y.]]		[[Category: Kim, Y.]]
	[[Category: MCSG, Midwest Center for Structural Genomics.]]		[[Category: MCSG, Midwest Center for Structural Genomics.]]
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	[[Category: Structural genomic]]		[[Category: Structural genomic]]
	[[Category: Transcription activation]]		[[Category: Transcription activation]]
-		+	[[Category: Transcription activator]]
-	~~''Page seeded by~~ [~~http~~:~~//oca.weizmann.ac.il/oca OCA~~ ] ~~on Mon Feb 16 16:44:51 2009''~~	+