1zr7 - Revision history

OCA at 08:12, 15 May 2024

OCA — Wed, 15 May 2024 08:12:25 GMT

←Older revision		Revision as of 08:12, 15 May 2024
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	==Solution structure of the first WW domain of FBP11==		==Solution structure of the first WW domain of FBP11==
-	<StructureSection load='1zr7' size='340' side='right'caption='[[1zr7~~]], [[NMR_Ensembles_of_Models \| 20 NMR models~~]]' scene=''>	+	<StructureSection load='1zr7' size='340' side='right'caption='[[1zr7]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1zr7]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Human Human~~]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZR7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1ZR7 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1zr7]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZR7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1ZR7 FirstGlance]. <br>
-	</td></tr><tr id='~~gene~~'><td class="sblockLbl"><b>[[~~Gene~~\|~~Gene~~:]]</b></td><td class="sblockDat"~~>FBP11 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&~~id=~~9606 HUMAN])~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1zr7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1zr7 OCA], [https://pdbe.org/1zr7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1zr7 RCSB], [https://www.ebi.ac.uk/pdbsum/1zr7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1zr7 ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1zr7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1zr7 OCA], [https://pdbe.org/1zr7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1zr7 RCSB], [https://www.ebi.ac.uk/pdbsum/1zr7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1zr7 ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/PR40A_HUMAN PR40A_HUMAN] Binds to WASL/N-WASP and suppresses its translocation from the nucleus to the cytoplasm, thereby inhibiting its cytoplasmic function (By similarity). Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the control of cell shape and migration. May play a role in cytokinesis. May be involved in pre-mRNA splicing.<ref>PMID:21834987</ref>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 30:		Line 32:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Human~~]]	+	[[Category: Homo sapiens]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Hino, Y]]	+	[[Category: Hino Y]]
-	[[Category: Kato, Y]]	+	[[Category: Kato Y]]
-	~~[[Category: Structural genomic~~]]	+	[[Category: Tanokura M]]
-	[[Category: Tanokura, M]]	+
-	~~[[Category: Beta sheet]]~~	+
-	~~[[Category: National project on protein structural and functional analyse]]~~	+
-	~~[[Category: Nppsfa]]~~	+
-	~~[[Category: Rsgi]]~~	+
-	~~[[Category: Signaling protein~~]]	+

OCA at 08:15, 27 January 2021

OCA — Wed, 27 Jan 2021 08:15:10 GMT

←Older revision		Revision as of 08:15, 27 January 2021
Line 1:		Line 1:

	==Solution structure of the first WW domain of FBP11==		==Solution structure of the first WW domain of FBP11==
-	<StructureSection load='1zr7' size='340' side='right' caption='[[1zr7]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>	+	<StructureSection load='1zr7' size='340' side='right'caption='[[1zr7]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1zr7]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Human Human]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZR7 OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1ZR7 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1zr7]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZR7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1ZR7 FirstGlance]. <br>
-	</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">FBP11 ([~~http~~://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>	+	</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">FBP11 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1zr7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1zr7 OCA], [~~http~~://pdbe.org/1zr7 PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=1zr7 RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/1zr7 PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=1zr7 ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1zr7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1zr7 OCA], [https://pdbe.org/1zr7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1zr7 RCSB], [https://www.ebi.ac.uk/pdbsum/1zr7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1zr7 ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 31:		Line 31:
	</StructureSection>		</StructureSection>
	[[Category: Human]]		[[Category: Human]]
		+	[[Category: Large Structures]]
	[[Category: Hino, Y]]		[[Category: Hino, Y]]
	[[Category: Kato, Y]]		[[Category: Kato, Y]]

OCA at 08:58, 2 May 2018

OCA — Wed, 02 May 2018 08:58:58 GMT

←Older revision		Revision as of 08:58, 2 May 2018
Line 1:		Line 1:
		+
	==Solution structure of the first WW domain of FBP11==		==Solution structure of the first WW domain of FBP11==
	<StructureSection load='1zr7' size='340' side='right' caption='[[1zr7]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>		<StructureSection load='1zr7' size='340' side='right' caption='[[1zr7]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>
Line 4:		Line 5:
	<table><tr><td colspan='2'>[[1zr7]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZR7 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ZR7 FirstGlance]. <br>		<table><tr><td colspan='2'>[[1zr7]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZR7 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ZR7 FirstGlance]. <br>
	</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">FBP11 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>		</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">FBP11 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1zr7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1zr7 OCA], [http://pdbe.org/1zr7 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1zr7 RCSB], [http://www.ebi.ac.uk/pdbsum/1zr7 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1zr7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1zr7 OCA], [http://pdbe.org/1zr7 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1zr7 RCSB], [http://www.ebi.ac.uk/pdbsum/1zr7 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1zr7 ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 10:		Line 11:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/zr/1zr7_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/zr/1zr7_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>

OCA at 19:57, 8 February 2016

OCA — Mon, 08 Feb 2016 19:57:12 GMT

←Older revision		Revision as of 19:57, 8 February 2016
Line 14:		Line 14:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1zr7 ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 14:53, 10 September 2015

OCA — Thu, 10 Sep 2015 14:53:06 GMT

←Older revision		Revision as of 14:53, 10 September 2015
Line 2:		Line 2:
	<StructureSection load='1zr7' size='340' side='right' caption='[[1zr7]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>		<StructureSection load='1zr7' size='340' side='right' caption='[[1zr7]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1zr7]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Homo_sapiens Homo sapiens~~]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZR7 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ZR7 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1zr7]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZR7 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ZR7 FirstGlance]. <br>
-	</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">FBP11 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 ~~Homo sapiens~~])</td></tr>	+	</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">FBP11 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1zr7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1zr7 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1zr7 RCSB], [http://www.ebi.ac.uk/pdbsum/1zr7 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1zr7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1zr7 OCA], [http://pdbe.org/1zr7 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1zr7 RCSB], [http://www.ebi.ac.uk/pdbsum/1zr7 PDBsum]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
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	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 1zr7" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Homo sapiens~~]]	+	[[Category: Human]]
	[[Category: Hino, Y]]		[[Category: Hino, Y]]
	[[Category: Kato, Y]]		[[Category: Kato, Y]]

OCA at 09:14, 8 January 2015

OCA — Thu, 08 Jan 2015 09:14:12 GMT

←Older revision		Revision as of 09:14, 8 January 2015
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1zr7]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZR7 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ZR7 FirstGlance]. <br>		<table><tr><td colspan='2'>[[1zr7]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZR7 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ZR7 FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">FBP11 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>	+	</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">FBP11 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1zr7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1zr7 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1zr7 RCSB], [http://www.ebi.ac.uk/pdbsum/1zr7 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1zr7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1zr7 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1zr7 RCSB], [http://www.ebi.ac.uk/pdbsum/1zr7 PDBsum]</span></td></tr>
-	<table>	+	</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 29:		Line 29:
	</StructureSection>		</StructureSection>
	[[Category: Homo sapiens]]		[[Category: Homo sapiens]]
-	[[Category: Hino, Y.]]	+	[[Category: Hino, Y]]
-	[[Category: Kato, Y.]]	+	[[Category: Kato, Y]]
-	[[Category: ~~RSGI, RIKEN~~ Structural ~~Genomics/Proteomics Initiative.~~]]	+	[[Category: Structural genomic]]
-	[[Category: Tanokura, M.]]	+	[[Category: Tanokura, M]]
	[[Category: Beta sheet]]		[[Category: Beta sheet]]
	[[Category: National project on protein structural and functional analyse]]		[[Category: National project on protein structural and functional analyse]]
	[[Category: Nppsfa]]		[[Category: Nppsfa]]
-	[[Category: Riken structural genomics/proteomics initiative]]
	[[Category: Rsgi]]		[[Category: Rsgi]]
	[[Category: Signaling protein]]		[[Category: Signaling protein]]
-	[[Category: Structural genomic]]

OCA at 01:46, 30 September 2014

OCA — Tue, 30 Sep 2014 01:46:21 GMT

←Older revision		Revision as of 01:46, 30 September 2014
Line 1:		Line 1:
-	[[~~Image~~:1zr7.~~png\|left~~\|200px]]	+	==Solution structure of the first WW domain of FBP11==
		+	<StructureSection load='1zr7' size='340' side='right' caption='[[1zr7]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[1zr7]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZR7 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ZR7 FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">FBP11 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1zr7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1zr7 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1zr7 RCSB], [http://www.ebi.ac.uk/pdbsum/1zr7 PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/zr/1zr7_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	The Group-II/III WW domains bind Pro-rich sequences, the most frequent protein motif found in eucaryotic genomes. We have proposed that the Group-II and -III WW domains be merged into a larger group because the members of each group have relatively wide specificity and bind to the common ligands [Kato et al., J Biol Chem 2004;279:31833-31841]. We have also proposed that Group-II/III has a common surface patch, the XP2 groove, to bind the ligands. The first WW domain of FBP11/HYPA is one of the Group-II/III WW domains. The solution structure of the 26 residue-long converged region exhibits an antiparallel triple stranded beta-sheet with a small hydrophobic core. The WW domain of FBP11/HYPA has both XP and XP2 grooves on its surface. Ligand titration by 1H-15N HSQC NMR spectra revealed that the WW domain of FBP11/HYPA binds all the peptides with the PL, PP, and PR motifs. The profile patterns of chemical shift perturbation were quite similar among the spectra titrated with all three ligands. In addition, the titration significantly shifts the signals of the residues that compose the XP2 groove. All these findings suggest the functional importance of the XP2 groove and group definition of Group-II/III of the WW domains.

-	~~{{STRUCTURE_1zr7\| PDB=1zr7 \| SCENE= }}~~	+	Solution structure and binding specificity of FBP11/HYPA WW domain as Group-II/III.,Kato Y, Hino Y, Nagata K, Tanokura M Proteins. 2006 Apr 1;63(1):227-34. PMID:16463264<ref>PMID:16463264</ref>

-	~~===Solution structure~~ of the ~~first WW domain of FBP11===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_16463264}}~~	+	== References ==
-		+	<references/>
-	~~==About this Structure==~~	+	__TOC__
-	~~[[1zr7]] is a 1 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Homo_sapiens Homo sapiens]~~. ~~Full experimental information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=1ZR7 OCA].~~	+	</StructureSection>
-		+
-	==~~Reference~~==	+
-	<~~ref group="xtra">PMID:016463264<~~/~~ref~~><~~references group="xtra"~~/>	+
	[[Category: Homo sapiens]]		[[Category: Homo sapiens]]
	[[Category: Hino, Y.]]		[[Category: Hino, Y.]]

OCA: Protected "1zr7" [edit=sysop:move=sysop]

OCA — Sat, 05 Jan 2013 17:15:23 GMT

Protected "1zr7" [edit=sysop:move=sysop]

←Older revision

Revision as of 17:15, 5 January 2013

OCA at 17:15, 5 January 2013

OCA — Sat, 05 Jan 2013 17:15:21 GMT

←Older revision		Revision as of 17:15, 5 January 2013
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-	{{Seed}}
	[[Image:1zr7.png\|left\|200px]]		[[Image:1zr7.png\|left\|200px]]

-	<!--
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	{{STRUCTURE_1zr7\| PDB=1zr7 \| SCENE= }}		{{STRUCTURE_1zr7\| PDB=1zr7 \| SCENE= }}

	===Solution structure of the first WW domain of FBP11===		===Solution structure of the first WW domain of FBP11===

-
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	{{ABSTRACT_PUBMED_16463264}}		{{ABSTRACT_PUBMED_16463264}}

	==About this Structure==		==About this Structure==
-	~~1ZR7~~ is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZR7 OCA].	+	[[1zr7]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZR7 OCA].

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~16463264~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:016463264</ref><references group="xtra"/>
	[[Category: Homo sapiens]]		[[Category: Homo sapiens]]
	[[Category: Hino, Y.]]		[[Category: Hino, Y.]]
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	[[Category: Riken structural genomics/proteomics initiative]]		[[Category: Riken structural genomics/proteomics initiative]]
	[[Category: Rsgi]]		[[Category: Rsgi]]
		+	[[Category: Signaling protein]]
	[[Category: Structural genomic]]		[[Category: Structural genomic]]
-
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 02:38:37 2009''

OCA at 00:38, 17 February 2009

OCA — Tue, 17 Feb 2009 00:38:38 GMT

←Older revision		Revision as of 00:38, 17 February 2009
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	==About this Structure==		==About this Structure==
-	1ZR7 is a ~~[[Single protein]]~~ structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZR7 OCA].	+	1ZR7 is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZR7 OCA].

	==Reference==		==Reference==
-	~~Solution structure and binding specificity of FBP11/HYPA WW domain as Group-II/III., Kato Y, Hino Y, Nagata K, Tanokura M, Proteins. 2006 Apr 1;63(1):227-34.~~ PMID:~~[http:~~//~~www.ncbi.nlm.nih.gov/pubmed/16463264 16463264]~~	+	<ref group="xtra">PMID:16463264</ref><references group="xtra"/>
	[[Category: Homo sapiens]]		[[Category: Homo sapiens]]
-	[[Category: Single protein]]
	[[Category: Hino, Y.]]		[[Category: Hino, Y.]]
	[[Category: Kato, Y.]]		[[Category: Kato, Y.]]
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	[[Category: Structural genomic]]		[[Category: Structural genomic]]

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on ~~Mon Jul 28 06~~:19:~~57 2008~~''	+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 02:38:37 2009''