1zud - Revision history

OCA at 07:14, 23 August 2023

OCA — Wed, 23 Aug 2023 07:14:59 GMT

←Older revision		Revision as of 07:14, 23 August 2023
Line 3:		Line 3:
	<StructureSection load='1zud' size='340' side='right'caption='[[1zud]], [[Resolution\|resolution]] 1.98Å' scene=''>		<StructureSection load='1zud' size='340' side='right'caption='[[1zud]], [[Resolution\|resolution]] 1.98Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1zud]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Ecoli Ecoli~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZUD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1ZUD FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1zud]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZUD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1ZUD FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.98Å</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1zud FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1zud OCA], [https://pdbe.org/1zud PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1zud RCSB], [https://www.ebi.ac.uk/pdbsum/1zud PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1zud ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1zud FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1zud OCA], [https://pdbe.org/1zud PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1zud RCSB], [https://www.ebi.ac.uk/pdbsum/1zud PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1zud ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[https://www.uniprot.org/uniprot/THIF_ECOLI THIF_ECOLI]] Catalyzes the adenylation by ATP of the carboxyl group of the C-terminal glycine of sulfur carrier protein ThiS. ~~[[https://www.uniprot.org/uniprot/THIS_ECOLI THIS_ECOLI]] Is the sulfur donor in the synthesis of the thiazole phosphate moiety of thiamine phosphate.<ref>PMID:9632726</ref>~~	+	[https://www.uniprot.org/uniprot/THIF_ECOLI THIF_ECOLI] Catalyzes the adenylation by ATP of the carboxyl group of the C-terminal glycine of sulfur carrier protein ThiS.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 32:		Line 33:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Ecoli~~]]	+	[[Category: Escherichia coli K-12]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Ealick~~, S E~~]]	+	[[Category: Ealick SE]]
-	[[Category: Lehmann, C]]	+	[[Category: Lehmann C]]
-	~~[[Category: Protein-protein complex]]~~	+
-	~~[[Category: These]]~~	+
-	~~[[Category: Thiamin]]~~	+
-	~~[[Category: Thiazole]]~~	+
-	~~[[Category: Thif]]~~	+
-	~~[[Category: Transferase-biosynthetic protein complex~~]]	+

OCA at 08:24, 10 November 2021

OCA — Wed, 10 Nov 2021 08:24:51 GMT

←Older revision		Revision as of 08:24, 10 November 2021
Line 3:		Line 3:
	<StructureSection load='1zud' size='340' side='right'caption='[[1zud]], [[Resolution\|resolution]] 1.98Å' scene=''>		<StructureSection load='1zud' size='340' side='right'caption='[[1zud]], [[Resolution\|resolution]] 1.98Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1zud]] is a 4 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Ecoli Ecoli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZUD OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1ZUD FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1zud]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Ecoli Ecoli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZUD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1ZUD FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1zud FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1zud OCA], [~~http~~://pdbe.org/1zud PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=1zud RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/1zud PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=1zud ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1zud FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1zud OCA], [https://pdbe.org/1zud PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1zud RCSB], [https://www.ebi.ac.uk/pdbsum/1zud PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1zud ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[~~http~~://www.uniprot.org/uniprot/THIF_ECOLI THIF_ECOLI]] Catalyzes the adenylation by ATP of the carboxyl group of the C-terminal glycine of sulfur carrier protein ThiS. [[~~http~~://www.uniprot.org/uniprot/THIS_ECOLI THIS_ECOLI]] Is the sulfur donor in the synthesis of the thiazole phosphate moiety of thiamine phosphate.<ref>PMID:9632726</ref>	+	[[https://www.uniprot.org/uniprot/THIF_ECOLI THIF_ECOLI]] Catalyzes the adenylation by ATP of the carboxyl group of the C-terminal glycine of sulfur carrier protein ThiS. [[https://www.uniprot.org/uniprot/THIS_ECOLI THIS_ECOLI]] Is the sulfur donor in the synthesis of the thiazole phosphate moiety of thiamine phosphate.<ref>PMID:9632726</ref>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]

OCA at 09:37, 5 February 2020

OCA — Wed, 05 Feb 2020 09:37:43 GMT

←Older revision		Revision as of 09:37, 5 February 2020
Line 1:		Line 1:

	==Structure of ThiS-ThiF protein complex==		==Structure of ThiS-ThiF protein complex==
-	<StructureSection load='1zud' size='340' side='right' caption='[[1zud]], [[Resolution\|resolution]] 1.98Å' scene=''>	+	<StructureSection load='1zud' size='340' side='right'caption='[[1zud]], [[Resolution\|resolution]] 1.98Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1zud]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Ecoli Ecoli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZUD OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ZUD FirstGlance]. <br>		<table><tr><td colspan='2'>[[1zud]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Ecoli Ecoli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZUD OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ZUD FirstGlance]. <br>
Line 33:		Line 33:
	</StructureSection>		</StructureSection>
	[[Category: Ecoli]]		[[Category: Ecoli]]
		+	[[Category: Large Structures]]
	[[Category: Ealick, S E]]		[[Category: Ealick, S E]]
	[[Category: Lehmann, C]]		[[Category: Lehmann, C]]

OCA at 09:03, 2 May 2018

OCA — Wed, 02 May 2018 09:03:18 GMT

←Older revision		Revision as of 09:03, 2 May 2018
Line 1:		Line 1:
		+
	==Structure of ThiS-ThiF protein complex==		==Structure of ThiS-ThiF protein complex==
	<StructureSection load='1zud' size='340' side='right' caption='[[1zud]], [[Resolution\|resolution]] 1.98Å' scene=''>		<StructureSection load='1zud' size='340' side='right' caption='[[1zud]], [[Resolution\|resolution]] 1.98Å' scene=''>
Line 4:		Line 5:
	<table><tr><td colspan='2'>[[1zud]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Ecoli Ecoli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZUD OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ZUD FirstGlance]. <br>		<table><tr><td colspan='2'>[[1zud]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Ecoli Ecoli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZUD OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ZUD FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1zud FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1zud OCA], [http://pdbe.org/1zud PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1zud RCSB], [http://www.ebi.ac.uk/pdbsum/1zud PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1zud FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1zud OCA], [http://pdbe.org/1zud PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1zud RCSB], [http://www.ebi.ac.uk/pdbsum/1zud PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1zud ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 12:		Line 13:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/zu/1zud_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/zu/1zud_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
Line 35:		Line 36:
	[[Category: Lehmann, C]]		[[Category: Lehmann, C]]
	[[Category: Protein-protein complex]]		[[Category: Protein-protein complex]]
		+	[[Category: These]]
	[[Category: Thiamin]]		[[Category: Thiamin]]
	[[Category: Thiazole]]		[[Category: Thiazole]]
	[[Category: Thif]]		[[Category: Thif]]
-	[[Category: These]]
	[[Category: Transferase-biosynthetic protein complex]]		[[Category: Transferase-biosynthetic protein complex]]

OCA at 14:53, 8 February 2016

OCA — Mon, 08 Feb 2016 14:53:14 GMT

←Older revision		Revision as of 14:53, 8 February 2016
Line 16:		Line 16:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1zud ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 12:40, 10 September 2015

OCA — Thu, 10 Sep 2015 12:40:39 GMT

←Older revision		Revision as of 12:40, 10 September 2015
Line 2:		Line 2:
	<StructureSection load='1zud' size='340' side='right' caption='[[1zud]], [[Resolution\|resolution]] 1.98Å' scene=''>		<StructureSection load='1zud' size='340' side='right' caption='[[1zud]], [[Resolution\|resolution]] 1.98Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1zud]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Escherichia_coli Escherichia coli~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZUD OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ZUD FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1zud]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Ecoli Ecoli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZUD OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ZUD FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1zud FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1zud OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1zud RCSB], [http://www.ebi.ac.uk/pdbsum/1zud PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1zud FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1zud OCA], [http://pdbe.org/1zud PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1zud RCSB], [http://www.ebi.ac.uk/pdbsum/1zud PDBsum]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 26:		Line 26:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 1zud" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Escherichia coli~~]]	+	[[Category: Ecoli]]
	[[Category: Ealick, S E]]		[[Category: Ealick, S E]]
	[[Category: Lehmann, C]]		[[Category: Lehmann, C]]

OCA at 00:09, 25 December 2014

OCA — Thu, 25 Dec 2014 00:09:23 GMT

←Older revision		Revision as of 00:09, 25 December 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1zud]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZUD OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ZUD FirstGlance]. <br>		<table><tr><td colspan='2'>[[1zud]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZUD OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ZUD FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene><br>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1zud FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1zud OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1zud RCSB], [http://www.ebi.ac.uk/pdbsum/1zud PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1zud FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1zud OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1zud RCSB], [http://www.ebi.ac.uk/pdbsum/1zud PDBsum]</span></td></tr>
-	<table>	+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/THIF_ECOLI THIF_ECOLI]] Catalyzes the adenylation by ATP of the carboxyl group of the C-terminal glycine of sulfur carrier protein ThiS. [[http://www.uniprot.org/uniprot/THIS_ECOLI THIS_ECOLI]] Is the sulfur donor in the synthesis of the thiazole phosphate moiety of thiamine phosphate.<ref>PMID:9632726</ref>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 29:		Line 31:
	</StructureSection>		</StructureSection>
	[[Category: Escherichia coli]]		[[Category: Escherichia coli]]
-	[[Category: Ealick, S E.]]	+	[[Category: Ealick, S E]]
-	[[Category: Lehmann, C.]]	+	[[Category: Lehmann, C]]
	[[Category: Protein-protein complex]]		[[Category: Protein-protein complex]]
	[[Category: Thiamin]]		[[Category: Thiamin]]

OCA at 02:40, 30 September 2014

OCA — Tue, 30 Sep 2014 02:40:00 GMT

←Older revision		Revision as of 02:40, 30 September 2014
Line 1:		Line 1:
-	[[~~Image~~:1zud.~~png\|left~~\|200px]]	+	==Structure of ThiS-ThiF protein complex==
		+	<StructureSection load='1zud' size='340' side='right' caption='[[1zud]], [[Resolution\|resolution]] 1.98Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[1zud]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZUD OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ZUD FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene><br>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1zud FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1zud OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1zud RCSB], [http://www.ebi.ac.uk/pdbsum/1zud PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/zu/1zud_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	We have determined the crystal structure of the Escherichia coli ThiS-ThiF protein complex at 2.0 A resolution. ThiS and ThiF are bacterial proteins involved in the synthesis of the thiazole moiety of thiamin. ThiF catalyzes the adenylation of the carboxy terminus of ThiS and the subsequent displacement of AMP catalyzed by ThiI-persulfide to give a ThiS-ThiI acyl disulfide. Disulfide interchange, involving Cys184 on ThiF, then generates the ThiS-ThiF acyl disulfide, which functions as the sulfur donor for thiazole formation. ThiS is a small 7.2 kDa protein that structurally resembles ubiquitin and the molybdopterin biosynthetic protein MoaD. ThiF is a 27 kDa protein with distinct sequence and structural similarity to the ubiquitin activating enzyme E1 and the molybdopterin biosynthetic protein MoeB. The ThiF-ThiS structure clarifies the mechanism of the sulfur transfer chemistry involved in thiazole biosynthesis.

-	~~{{STRUCTURE_1zud\| PDB=1zud \| SCENE= }}~~	+	Structure of the Escherichia coli ThiS-ThiF complex, a key component of the sulfur transfer system in thiamin biosynthesis.,Lehmann C, Begley TP, Ealick SE Biochemistry. 2006 Jan 10;45(1):11-9. PMID:16388576<ref>PMID:16388576</ref>

-	~~===Structure~~ of ~~ThiS-ThiF protein complex===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_16388576}}~~	+	== References ==
-		+	<references/>
-	~~==About this Structure==~~	+	__TOC__
-	~~[[1zud]] is a 4 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Escherichia_coli Escherichia coli]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=1ZUD OCA].~~	+	</StructureSection>
-		+
-	==~~Reference~~==	+
-	<~~ref group="xtra">PMID:016388576<~~/~~ref~~><~~references group="xtra"~~/>	+
	[[Category: Escherichia coli]]		[[Category: Escherichia coli]]
	[[Category: Ealick, S E.]]		[[Category: Ealick, S E.]]

OCA: Protected "1zud" [edit=sysop:move=sysop]

OCA — Sat, 05 Jan 2013 17:21:30 GMT

Protected "1zud" [edit=sysop:move=sysop]

←Older revision

Revision as of 17:21, 5 January 2013

OCA at 17:21, 5 January 2013

OCA — Sat, 05 Jan 2013 17:21:28 GMT

←Older revision		Revision as of 17:21, 5 January 2013
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-	{{Seed}}
	[[Image:1zud.png\|left\|200px]]		[[Image:1zud.png\|left\|200px]]

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	{{STRUCTURE_1zud\| PDB=1zud \| SCENE= }}		{{STRUCTURE_1zud\| PDB=1zud \| SCENE= }}

	===Structure of ThiS-ThiF protein complex===		===Structure of ThiS-ThiF protein complex===

-
-	<!--
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	{{ABSTRACT_PUBMED_16388576}}		{{ABSTRACT_PUBMED_16388576}}

	==About this Structure==		==About this Structure==
-	~~1ZUD~~ is a 4 ~~chains~~ structure ~~of sequences~~ from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZUD OCA].	+	[[1zud]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZUD OCA].

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~16388576~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:016388576</ref><references group="xtra"/>
	[[Category: Escherichia coli]]		[[Category: Escherichia coli]]
	[[Category: Ealick, S E.]]		[[Category: Ealick, S E.]]
Line 32:		Line 20:
	[[Category: Thif]]		[[Category: Thif]]
	[[Category: These]]		[[Category: These]]
-		+	[[Category: Transferase-biosynthetic protein complex]]
-	~~''Page seeded by~~ [~~http~~:~~//oca.weizmann.ac.il/oca OCA~~ ] ~~on Mon Feb 16 23:48:18 2009''~~	+