2aa1 - Revision history

OCA at 08:16, 25 October 2023

OCA — Wed, 25 Oct 2023 08:16:52 GMT

←Older revision		Revision as of 08:16, 25 October 2023
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	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2aa1]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Trematomus_newnesi Trematomus newnesi]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2AA1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2AA1 FirstGlance]. <br>		<table><tr><td colspan='2'>[[2aa1]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Trematomus_newnesi Trematomus newnesi]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2AA1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2AA1 FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.8Å</td></tr>
-	<tr id='~~NonStdRes~~'><td class="sblockLbl"><b>[[~~Non-Standard_Residue~~\|~~NonStd Res~~:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACE:ACETYL+GROUP'>ACE</scene></td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACE:ACETYL+GROUP'>ACE</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2aa1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2aa1 OCA], [https://pdbe.org/2aa1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2aa1 RCSB], [https://www.ebi.ac.uk/pdbsum/2aa1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2aa1 ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2aa1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2aa1 OCA], [https://pdbe.org/2aa1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2aa1 RCSB], [https://www.ebi.ac.uk/pdbsum/2aa1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2aa1 ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/HBA1_TRENE HBA1_TRENE]
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 36:		Line 38:
	[[Category: Large Structures]]		[[Category: Large Structures]]
	[[Category: Trematomus newnesi]]		[[Category: Trematomus newnesi]]
-	[[Category: Bonomi, G]]	+	[[Category: Bonomi G]]
-	[[Category: ~~Lubrano, M C~~]]	+	[[Category: Di Prisco G]]
-	[[Category: ~~Mazzarella, L~~]]	+	[[Category: Lubrano MC]]
-	[[Category: ~~Merlino, A~~]]	+	[[Category: Mazzarella L]]
-	[[Category: ~~Prisco, G Di~~]]	+	[[Category: Merlino A]]
-	[[Category: Riccio, A]]	+	[[Category: Riccio A]]
-	[[Category: Verde, C]]	+	[[Category: Verde C]]
-	[[Category: Vergara, A]]	+	[[Category: Vergara A]]
-	[[Category: Vitagliano, L]]	+	[[Category: Vitagliano L]]
-	~~[[Category: Antarctic fish]]~~	+
-	~~[[Category: Cooperativity]]~~	+
-	~~[[Category: Hemoglobin]]~~	+
-	~~[[Category: Oxygen storage-transport complex]]~~	+
-	~~[[Category: Root effect~~]]	+

OCA at 14:38, 17 November 2021

OCA — Wed, 17 Nov 2021 14:38:23 GMT

←Older revision		Revision as of 14:38, 17 November 2021
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	<StructureSection load='2aa1' size='340' side='right'caption='[[2aa1]], [[Resolution\|resolution]] 1.80Å' scene=''>		<StructureSection load='2aa1' size='340' side='right'caption='[[2aa1]], [[Resolution\|resolution]] 1.80Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2aa1]] is a 4 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Trematomus_newnesi Trematomus newnesi]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2AA1 OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2AA1 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2aa1]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Trematomus_newnesi Trematomus newnesi]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2AA1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2AA1 FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene></td></tr>
	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACE:ACETYL+GROUP'>ACE</scene></td></tr>		<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACE:ACETYL+GROUP'>ACE</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2aa1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2aa1 OCA], [~~http~~://pdbe.org/2aa1 PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=2aa1 RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/2aa1 PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=2aa1 ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2aa1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2aa1 OCA], [https://pdbe.org/2aa1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2aa1 RCSB], [https://www.ebi.ac.uk/pdbsum/2aa1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2aa1 ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==

OCA at 05:19, 13 February 2020

OCA — Thu, 13 Feb 2020 05:19:11 GMT

←Older revision		Revision as of 05:19, 13 February 2020
Line 1:		Line 1:

	==Crystal structure of the cathodic hemoglobin isolated from the Antarctic fish Trematomus Newnesi==		==Crystal structure of the cathodic hemoglobin isolated from the Antarctic fish Trematomus Newnesi==
-	<StructureSection load='2aa1' size='340' side='right' caption='[[2aa1]], [[Resolution\|resolution]] 1.80Å' scene=''>	+	<StructureSection load='2aa1' size='340' side='right'caption='[[2aa1]], [[Resolution\|resolution]] 1.80Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2aa1]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Trematomus_newnesi Trematomus newnesi]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2AA1 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2AA1 FirstGlance]. <br>		<table><tr><td colspan='2'>[[2aa1]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Trematomus_newnesi Trematomus newnesi]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2AA1 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2AA1 FirstGlance]. <br>
Line 34:		Line 34:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Large Structures]]
	[[Category: Trematomus newnesi]]		[[Category: Trematomus newnesi]]
	[[Category: Bonomi, G]]		[[Category: Bonomi, G]]

OCA at 07:10, 9 May 2018

OCA — Wed, 09 May 2018 07:10:15 GMT

←Older revision		Revision as of 07:10, 9 May 2018
Line 1:		Line 1:
		+
	==Crystal structure of the cathodic hemoglobin isolated from the Antarctic fish Trematomus Newnesi==		==Crystal structure of the cathodic hemoglobin isolated from the Antarctic fish Trematomus Newnesi==
	<StructureSection load='2aa1' size='340' side='right' caption='[[2aa1]], [[Resolution\|resolution]] 1.80Å' scene=''>		<StructureSection load='2aa1' size='340' side='right' caption='[[2aa1]], [[Resolution\|resolution]] 1.80Å' scene=''>
Line 5:		Line 6:
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene></td></tr>
	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACE:ACETYL+GROUP'>ACE</scene></td></tr>		<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACE:ACETYL+GROUP'>ACE</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2aa1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2aa1 OCA], [http://pdbe.org/2aa1 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2aa1 RCSB], [http://www.ebi.ac.uk/pdbsum/2aa1 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2aa1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2aa1 OCA], [http://pdbe.org/2aa1 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2aa1 RCSB], [http://www.ebi.ac.uk/pdbsum/2aa1 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2aa1 ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 11:		Line 12:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/aa/2aa1_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/aa/2aa1_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2aa1 ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 23:13, 11 September 2015

OCA — Fri, 11 Sep 2015 23:13:08 GMT

←Older revision		Revision as of 23:13, 11 September 2015
Line 5:		Line 5:
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene></td></tr>
	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACE:ACETYL+GROUP'>ACE</scene></td></tr>		<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACE:ACETYL+GROUP'>ACE</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2aa1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2aa1 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2aa1 RCSB], [http://www.ebi.ac.uk/pdbsum/2aa1 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2aa1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2aa1 OCA], [http://pdbe.org/2aa1 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2aa1 RCSB], [http://www.ebi.ac.uk/pdbsum/2aa1 PDBsum]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 25:		Line 25:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 2aa1" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==

OCA at 20:41, 25 December 2014

OCA — Thu, 25 Dec 2014 20:41:58 GMT

←Older revision		Revision as of 20:41, 25 December 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2aa1]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Trematomus_newnesi Trematomus newnesi]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2AA1 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2AA1 FirstGlance]. <br>		<table><tr><td colspan='2'>[[2aa1]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Trematomus_newnesi Trematomus newnesi]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2AA1 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2AA1 FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene><br>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene></td></tr>
-	<tr><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACE:ACETYL+GROUP'>ACE</scene></td></tr>	+	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACE:ACETYL+GROUP'>ACE</scene></td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2aa1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2aa1 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2aa1 RCSB], [http://www.ebi.ac.uk/pdbsum/2aa1 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2aa1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2aa1 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2aa1 RCSB], [http://www.ebi.ac.uk/pdbsum/2aa1 PDBsum]</span></td></tr>
-	<table>	+	</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 33:		Line 33:
	</StructureSection>		</StructureSection>
	[[Category: Trematomus newnesi]]		[[Category: Trematomus newnesi]]
-	[[Category: Bonomi, G.]]	+	[[Category: Bonomi, G]]
-	[[Category: Lubrano, M C.]]	+	[[Category: Lubrano, M C]]
-	[[Category: Mazzarella, L.]]	+	[[Category: Mazzarella, L]]
-	[[Category: Merlino, A.]]	+	[[Category: Merlino, A]]
-	[[Category: Prisco, G Di.]]	+	[[Category: Prisco, G Di]]
-	[[Category: Riccio, A.]]	+	[[Category: Riccio, A]]
-	[[Category: Verde, C.]]	+	[[Category: Verde, C]]
-	[[Category: Vergara, A.]]	+	[[Category: Vergara, A]]
-	[[Category: Vitagliano, L.]]	+	[[Category: Vitagliano, L]]
	[[Category: Antarctic fish]]		[[Category: Antarctic fish]]
	[[Category: Cooperativity]]		[[Category: Cooperativity]]

OCA at 04:07, 29 September 2014

OCA — Mon, 29 Sep 2014 04:07:43 GMT

←Older revision		Revision as of 04:07, 29 September 2014
Line 1:		Line 1:
-	[[~~Image:~~2aa1.~~png~~\|~~left~~\|200px]]	+	==Crystal structure of the cathodic hemoglobin isolated from the Antarctic fish Trematomus Newnesi==
		+	<StructureSection load='2aa1' size='340' side='right' caption='[[2aa1]], [[Resolution\|resolution]] 1.80Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[2aa1]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Trematomus_newnesi Trematomus newnesi]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2AA1 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2AA1 FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene><br>
		+	<tr><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACE:ACETYL+GROUP'>ACE</scene></td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2aa1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2aa1 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2aa1 RCSB], [http://www.ebi.ac.uk/pdbsum/2aa1 PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/aa/2aa1_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	The cathodic hemoglobin component of the Antarctic fish Trematomus newnesi (HbCTn) is a Root-effect protein. The interpretation of its functional properties in relation to its sequence is puzzling. Indeed, HbCTn sequence is characterized by an extremely low histidyl content, and in particular by the lack of His146beta and His69beta, which are believed to be important in Bohr and Root effects, respectively. Furthermore, previous analyses suggested that the local environment of Asp95alpha, Asp99beta, and Asp101beta should not be appropriate for the formation of Asp-Asp interactions, which are important for the Root effect. Here, we report the high-resolution crystal structure of the deoxy form of HbCTn. Our data provide a structural interpretation for the very low oxygen affinity of the protein and insights into the structural determinants of the Root effect protein. The structure demonstrates that the presence of Ile41alpha and Ser97alpha at the alpha1beta2 interface does not prevent the formation of the inter-Asp interactions in HbCTn, as previous studies had suggested. The present data indicate that the hydrogen bond formed between Asp95alpha and Asp101beta, which is stabilized by Asp99beta, is per se sufficient to generate the Root effect, and it is the minimal structural requirement needed for the design of Root-effect Hbs.

-	~~{{STRUCTURE_2aa1\| PDB=2aa1 \| SCENE= }}~~	+	Minimal structural requirements for root effect: crystal structure of the cathodic hemoglobin isolated from the antarctic fish Trematomus newnesi.,Mazzarella L, Bonomi G, Lubrano MC, Merlino A, Riccio A, Vergara A, Vitagliano L, Verde C, di Prisco G Proteins. 2006 Feb 1;62(2):316-21. PMID:16299734<ref>PMID:16299734</ref>

-	~~===Crystal structure~~ of the ~~cathodic hemoglobin isolated from the Antarctic fish Trematomus Newnesi===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_16299734}}~~	+
-		+
-	~~==About this Structure==~~	+
-	~~[[2aa1]] is a 4 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Trematomus_newnesi Trematomus newnesi]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=2AA1 OCA].~~	+

	==See Also==		==See Also==
-	*[[Hemoglobin\|Hemoglobin]]	+	*[[Hemoglobin 3D structures\|Hemoglobin 3D structures]]
-		+	== References ==
-	==~~Reference~~==	+	<references/>
-	<~~ref group="xtra">PMID:016299734<~~/~~ref~~><~~ref group="xtra">PMID:010222199</ref><references group="xtra"~~/>	+	__TOC__
		+	</StructureSection>
	[[Category: Trematomus newnesi]]		[[Category: Trematomus newnesi]]
	[[Category: Bonomi, G.]]		[[Category: Bonomi, G.]]

OCA at 21:23, 20 October 2012

OCA — Sat, 20 Oct 2012 21:23:13 GMT

←Older revision		Revision as of 21:23, 20 October 2012
Line 8:		Line 8:

	==About this Structure==		==About this Structure==
-	[[2aa1]] is a 4 chain structure ~~of [[Hemoglobin]]~~ with sequence from [http://en.wikipedia.org/wiki/Trematomus_newnesi Trematomus newnesi]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2AA1 OCA].	+	[[2aa1]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Trematomus_newnesi Trematomus newnesi]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2AA1 OCA].

	==See Also==		==See Also==

OCA at 13:05, 27 July 2012

OCA — Fri, 27 Jul 2012 13:05:47 GMT

←Older revision		Revision as of 13:05, 27 July 2012
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	[[Image:2aa1.png\|left\|200px]]		[[Image:2aa1.png\|left\|200px]]

-	<!--
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-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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	{{STRUCTURE_2aa1\| PDB=2aa1 \| SCENE= }}		{{STRUCTURE_2aa1\| PDB=2aa1 \| SCENE= }}

	===Crystal structure of the cathodic hemoglobin isolated from the Antarctic fish Trematomus Newnesi===		===Crystal structure of the cathodic hemoglobin isolated from the Antarctic fish Trematomus Newnesi===

-
-	<!--
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-	(as it appears on PubMed at http://www.pubmed.gov), where 16299734 is the PubMed ID number.
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	{{ABSTRACT_PUBMED_16299734}}		{{ABSTRACT_PUBMED_16299734}}

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	==See Also==		==See Also==
-	*[[Hemoglobin]]	+	*[[Hemoglobin\|Hemoglobin]]

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~16299734~~</ref><ref group="xtra">PMID:~~10222199~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:016299734</ref><ref group="xtra">PMID:010222199</ref><references group="xtra"/>
	[[Category: Trematomus newnesi]]		[[Category: Trematomus newnesi]]
	[[Category: Bonomi, G.]]		[[Category: Bonomi, G.]]
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	[[Category: Cooperativity]]		[[Category: Cooperativity]]
	[[Category: Hemoglobin]]		[[Category: Hemoglobin]]
-	[[Category: Oxygen storage/transport complex]]	+	[[Category: Oxygen storage-transport complex]]
	[[Category: Root effect]]		[[Category: Root effect]]

OCA: Protected "2aa1" [edit=sysop:move=sysop]

OCA — Tue, 15 Mar 2011 00:00:39 GMT

Protected "2aa1" [edit=sysop:move=sysop]

←Older revision

Revision as of 00:00, 15 March 2011