2alw - Revision history

OCA at 07:26, 23 August 2023

OCA — Wed, 23 Aug 2023 07:26:13 GMT

←Older revision		Revision as of 07:26, 23 August 2023
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	==Golgi alpha-mannosidase II complex with Noeuromycin==		==Golgi alpha-mannosidase II complex with Noeuromycin==
-	<StructureSection load='2alw' size='340' side='right'caption='[[2alw]]' scene=''>	+	<StructureSection load='2alw' size='340' side='right'caption='[[2alw]], [[Resolution\|resolution]] 1.86Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ALW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2ALW FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2alw]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ALW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2ALW FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2alw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2alw OCA], [https://pdbe.org/2alw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2alw RCSB], [https://www.ebi.ac.uk/pdbsum/2alw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2alw ProSAT]</span></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.86Å</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MNM:(2S,3S,4R,5R)-2,3,4-TRIHYDROXY-5-HYDROXYMETHYL-PIPERIDINE'>MNM</scene>, <scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2alw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2alw OCA], [https://pdbe.org/2alw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2alw RCSB], [https://www.ebi.ac.uk/pdbsum/2alw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2alw ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/MAN2_DROME MAN2_DROME] Catalyzes the first committed step in the biosynthesis of complex N-glycans. It controls conversion of high mannose to complex N-glycans; the final hydrolytic step in the N-glycan maturation pathway (By similarity).
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 21:		Line 25:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Drosophila melanogaster]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
	[[Category: Bols MB]]		[[Category: Bols MB]]

OCA at 11:32, 3 February 2021

OCA — Wed, 03 Feb 2021 11:32:02 GMT

←Older revision		Revision as of 11:32, 3 February 2021
Line 1:		Line 1:

	==Golgi alpha-mannosidase II complex with Noeuromycin==		==Golgi alpha-mannosidase II complex with Noeuromycin==
-	<StructureSection load='2alw' size='340' side='right' caption='[[2alw]]~~, [[Resolution\|resolution]] 1.86Å~~' scene=''>	+	<StructureSection load='2alw' size='340' side='right'caption='[[2alw]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>~~[[2alw]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Drome Drome].~~ Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ALW OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2ALW FirstGlance]. <br>	+	<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ALW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2ALW FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MNM:(2S,3S,4R,5R)-2,3,4-TRIHYDROXY-5-HYDROXYMETHYL-PIPERIDINE'>MNM</scene>, <scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2alw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2alw OCA], [https://pdbe.org/2alw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2alw RCSB], [https://www.ebi.ac.uk/pdbsum/2alw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2alw ProSAT]</span></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1hty\|1hty]], [[1hww\|1hww]], [[1hxk\|1hxk]], [[1ps2\|1ps2]], [[1qwn\|1qwn]], [[1qx1\|1qx1]], [[1r33\|1r33]], [[1r34\|1r34]], [[1tqs\|1tqs]], [[1tqt\|1tqt]], [[1tqu\|1tqu]], [[1tqw\|1tqw]]</td></tr>	+
-	~~<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">GmII ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=7227 DROME])</td></tr>~~	+
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Mannosyl-oligosaccharide_1,3-1,6-alpha-mannosidase Mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.114 3.2.1.114] </span></td></tr>	+
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2alw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2alw OCA], [~~http~~://pdbe.org/2alw PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=2alw RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/2alw PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=2alw ProSAT]</span></td></tr>	+
	</table>		</table>
-	== Function ==
-	[[http://www.uniprot.org/uniprot/MAN2_DROME MAN2_DROME]] Catalyzes the first committed step in the biosynthesis of complex N-glycans. It controls conversion of high mannose to complex N-glycans; the final hydrolytic step in the N-glycan maturation pathway (By similarity).
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 24:		Line 18:

	==See Also==		==See Also==
-	*[[Mannosidase\|Mannosidase]]	+	*[[Mannosidase 3D structures\|Mannosidase 3D structures]]
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Drome]]~~	+	[[Category: Large Structures]]
-	~~[[Category: Mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase~~]]	+	[[Category: Bols MB]]
-	[[Category: Bols~~, M B~~]]	+	[[Category: Kuntz DA]]
-	[[Category: Kuntz~~, D A~~]]	+	[[Category: Liu H]]
-	[[Category: Liu, H]]	+	[[Category: Rose DR]]
-	[[Category: Rose~~, D R]]~~	+
-	~~[[Category: Glycosyl hydrolase family 38]]~~	+
-	~~[[Category: Hydrolase~~]]	+

OCA at 06:52, 9 May 2018

OCA — Wed, 09 May 2018 06:52:23 GMT

←Older revision		Revision as of 06:52, 9 May 2018
Line 1:		Line 1:
		+
	==Golgi alpha-mannosidase II complex with Noeuromycin==		==Golgi alpha-mannosidase II complex with Noeuromycin==
	<StructureSection load='2alw' size='340' side='right' caption='[[2alw]], [[Resolution\|resolution]] 1.86Å' scene=''>		<StructureSection load='2alw' size='340' side='right' caption='[[2alw]], [[Resolution\|resolution]] 1.86Å' scene=''>
Line 7:		Line 8:
	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">GmII ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=7227 DROME])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">GmII ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=7227 DROME])</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Mannosyl-oligosaccharide_1,3-1,6-alpha-mannosidase Mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.114 3.2.1.114] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Mannosyl-oligosaccharide_1,3-1,6-alpha-mannosidase Mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.114 3.2.1.114] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2alw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2alw OCA], [http://pdbe.org/2alw PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2alw RCSB], [http://www.ebi.ac.uk/pdbsum/2alw PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2alw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2alw OCA], [http://pdbe.org/2alw PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2alw RCSB], [http://www.ebi.ac.uk/pdbsum/2alw PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2alw ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 15:		Line 16:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/al/2alw_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/al/2alw_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2alw ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>

OCA at 22:54, 11 September 2015

OCA — Fri, 11 Sep 2015 22:54:47 GMT

←Older revision		Revision as of 22:54, 11 September 2015
Line 2:		Line 2:
	<StructureSection load='2alw' size='340' side='right' caption='[[2alw]], [[Resolution\|resolution]] 1.86Å' scene=''>		<StructureSection load='2alw' size='340' side='right' caption='[[2alw]], [[Resolution\|resolution]] 1.86Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2alw]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Drosophila_melanogaster Drosophila melanogaster~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ALW OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ALW FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2alw]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Drome Drome]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ALW OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ALW FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MNM:(2S,3S,4R,5R)-2,3,4-TRIHYDROXY-5-HYDROXYMETHYL-PIPERIDINE'>MNM</scene>, <scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MNM:(2S,3S,4R,5R)-2,3,4-TRIHYDROXY-5-HYDROXYMETHYL-PIPERIDINE'>MNM</scene>, <scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1hty\|1hty]], [[1hww\|1hww]], [[1hxk\|1hxk]], [[1ps2\|1ps2]], [[1qwn\|1qwn]], [[1qx1\|1qx1]], [[1r33\|1r33]], [[1r34\|1r34]], [[1tqs\|1tqs]], [[1tqt\|1tqt]], [[1tqu\|1tqu]], [[1tqw\|1tqw]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1hty\|1hty]], [[1hww\|1hww]], [[1hxk\|1hxk]], [[1ps2\|1ps2]], [[1qwn\|1qwn]], [[1qx1\|1qx1]], [[1r33\|1r33]], [[1r34\|1r34]], [[1tqs\|1tqs]], [[1tqt\|1tqt]], [[1tqu\|1tqu]], [[1tqw\|1tqw]]</td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">GmII ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=7227 ~~Drosophila melanogaster~~])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">GmII ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=7227 DROME])</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Mannosyl-oligosaccharide_1,3-1,6-alpha-mannosidase Mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.114 3.2.1.114] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Mannosyl-oligosaccharide_1,3-1,6-alpha-mannosidase Mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.114 3.2.1.114] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2alw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2alw OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2alw RCSB], [http://www.ebi.ac.uk/pdbsum/2alw PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2alw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2alw OCA], [http://pdbe.org/2alw PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2alw RCSB], [http://www.ebi.ac.uk/pdbsum/2alw PDBsum]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 26:		Line 26:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Drosophila melanogaster~~]]	+	[[Category: Drome]]
	[[Category: Mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase]]		[[Category: Mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase]]
	[[Category: Bols, M B]]		[[Category: Bols, M B]]

OCA at 20:32, 25 December 2014

OCA — Thu, 25 Dec 2014 20:32:20 GMT

←Older revision		Revision as of 20:32, 25 December 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2alw]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ALW OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ALW FirstGlance]. <br>		<table><tr><td colspan='2'>[[2alw]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ALW OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ALW FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MNM:(2S,3S,4R,5R)-2,3,4-TRIHYDROXY-5-HYDROXYMETHYL-PIPERIDINE'>MNM</scene>, <scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene><br>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MNM:(2S,3S,4R,5R)-2,3,4-TRIHYDROXY-5-HYDROXYMETHYL-PIPERIDINE'>MNM</scene>, <scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
-	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1hty\|1hty]], [[1hww\|1hww]], [[1hxk\|1hxk]], [[1ps2\|1ps2]], [[1qwn\|1qwn]], [[1qx1\|1qx1]], [[1r33\|1r33]], [[1r34\|1r34]], [[1tqs\|1tqs]], [[1tqt\|1tqt]], [[1tqu\|1tqu]], [[1tqw\|1tqw]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1hty\|1hty]], [[1hww\|1hww]], [[1hxk\|1hxk]], [[1ps2\|1ps2]], [[1qwn\|1qwn]], [[1qx1\|1qx1]], [[1r33\|1r33]], [[1r34\|1r34]], [[1tqs\|1tqs]], [[1tqt\|1tqt]], [[1tqu\|1tqu]], [[1tqw\|1tqw]]</td></tr>
-	<tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">GmII ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=7227 Drosophila melanogaster])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">GmII ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=7227 Drosophila melanogaster])</td></tr>
-	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Mannosyl-oligosaccharide_1,3-1,6-alpha-mannosidase Mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.114 3.2.1.114] </span></td></tr>	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Mannosyl-oligosaccharide_1,3-1,6-alpha-mannosidase Mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.114 3.2.1.114] </span></td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2alw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2alw OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2alw RCSB], [http://www.ebi.ac.uk/pdbsum/2alw PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2alw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2alw OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2alw RCSB], [http://www.ebi.ac.uk/pdbsum/2alw PDBsum]</span></td></tr>
-	<table>	+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/MAN2_DROME MAN2_DROME]] Catalyzes the first committed step in the biosynthesis of complex N-glycans. It controls conversion of high mannose to complex N-glycans; the final hydrolytic step in the N-glycan maturation pathway (By similarity).
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 26:		Line 28:
	[[Category: Drosophila melanogaster]]		[[Category: Drosophila melanogaster]]
	[[Category: Mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase]]		[[Category: Mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase]]
-	[[Category: Bols, M B.]]	+	[[Category: Bols, M B]]
-	[[Category: Kuntz, D A.]]	+	[[Category: Kuntz, D A]]
-	[[Category: Liu, H.]]	+	[[Category: Liu, H]]
-	[[Category: Rose, D R.]]	+	[[Category: Rose, D R]]
	[[Category: Glycosyl hydrolase family 38]]		[[Category: Glycosyl hydrolase family 38]]
	[[Category: Hydrolase]]		[[Category: Hydrolase]]

OCA at 03:55, 29 September 2014

OCA — Mon, 29 Sep 2014 03:55:28 GMT

←Older revision		Revision as of 03:55, 29 September 2014
Line 1:		Line 1:
-	~~[[Image:2alw.png\|left\|200px]]~~	+	==Golgi alpha-mannosidase II complex with Noeuromycin==
-		+	<StructureSection load='2alw' size='340' side='right' caption='[[2alw]], [[Resolution\|resolution]] 1.86Å' scene=''>
-	~~{{STRUCTURE_2alw\| PDB=2alw \| SCENE= }}~~	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[2alw]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ALW OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ALW FirstGlance]. <br>
-	===Golgi alpha-mannosidase II complex with Noeuromycin===	+	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MNM:(2S,3S,4R,5R)-2,3,4-TRIHYDROXY-5-HYDROXYMETHYL-PIPERIDINE'>MNM</scene>, <scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene><br>
-		+	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1hty\|1hty]], [[1hww\|1hww]], [[1hxk\|1hxk]], [[1ps2\|1ps2]], [[1qwn\|1qwn]], [[1qx1\|1qx1]], [[1r33\|1r33]], [[1r34\|1r34]], [[1tqs\|1tqs]], [[1tqt\|1tqt]], [[1tqu\|1tqu]], [[1tqw\|1tqw]]</td></tr>
-		+	<tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">GmII ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=7227 Drosophila melanogaster])</td></tr>
-	==~~About this Structure~~==	+	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Mannosyl-oligosaccharide_1,3-1,6-alpha-mannosidase Mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.114 3.2.1.114] </span></td></tr>
-	[[2alw]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ALW OCA].	+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2alw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2alw OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2alw RCSB], [http://www.ebi.ac.uk/pdbsum/2alw PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/al/2alw_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>

	==See Also==		==See Also==
	*[[Mannosidase\|Mannosidase]]		*[[Mannosidase\|Mannosidase]]
		+	__TOC__
		+	</StructureSection>
	[[Category: Drosophila melanogaster]]		[[Category: Drosophila melanogaster]]
	[[Category: Mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase]]		[[Category: Mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase]]

OCA at 21:09, 20 October 2012

OCA — Sat, 20 Oct 2012 21:09:45 GMT

←Older revision		Revision as of 21:09, 20 October 2012
Line 7:		Line 7:

	==About this Structure==		==About this Structure==
-	[[2alw]] is a 1 chain structure ~~of [[Mannosidase]]~~ with sequence from [http://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ALW OCA].	+	[[2alw]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ALW OCA].

	==See Also==		==See Also==

OCA: Protected "2alw" [edit=sysop:move=sysop]

OCA — Fri, 27 Jul 2012 12:44:49 GMT

Protected "2alw" [edit=sysop:move=sysop]

←Older revision

Revision as of 12:44, 27 July 2012

OCA at 12:44, 27 July 2012

OCA — Fri, 27 Jul 2012 12:44:47 GMT

←Older revision		Revision as of 12:44, 27 July 2012
Line 1:		Line 1:
-	{{Seed}}
	[[Image:2alw.png\|left\|200px]]		[[Image:2alw.png\|left\|200px]]

-	<!--
-	The line below this paragraph, containing "STRUCTURE_2alw", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_2alw\| PDB=2alw \| SCENE= }}		{{STRUCTURE_2alw\| PDB=2alw \| SCENE= }}

Line 14:		Line 7:

	==About this Structure==		==About this Structure==
-	~~2ALW~~ is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ALW OCA].	+	[[2alw]] is a 1 chain structure of [[Mannosidase]] with sequence from [http://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ALW OCA].
		+
		+	==See Also==
		+	*[[Mannosidase\|Mannosidase]]
	[[Category: Drosophila melanogaster]]		[[Category: Drosophila melanogaster]]
	[[Category: Mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase]]		[[Category: Mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase]]
Line 22:		Line 18:
	[[Category: Rose, D R.]]		[[Category: Rose, D R.]]
	[[Category: Glycosyl hydrolase family 38]]		[[Category: Glycosyl hydrolase family 38]]
-		+	[[Category: Hydrolase]]
-	~~''Page seeded by~~ [~~http~~:~~//oca.weizmann.ac.il/oca OCA~~ ] ~~on Wed Feb 18 06:21:35 2009''~~	+

OCA at 04:21, 18 February 2009

OCA — Wed, 18 Feb 2009 04:21:36 GMT

←Older revision		Revision as of 04:21, 18 February 2009
Line 1:		Line 1:
-	[[Image:2alw.~~gif~~\|left\|200px]]	+	{{Seed}}
		+	[[Image:2alw.png\|left\|200px]]

	<!--		<!--
Line 9:		Line 10:
	{{STRUCTURE_2alw\| PDB=2alw \| SCENE= }}		{{STRUCTURE_2alw\| PDB=2alw \| SCENE= }}

-	~~'''~~Golgi alpha-mannosidase II complex with Noeuromycin~~'''~~	+	===Golgi alpha-mannosidase II complex with Noeuromycin===


	==About this Structure==		==About this Structure==
-	2ALW is a ~~[[Single protein]]~~ structure of sequence from [http://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ALW OCA].	+	2ALW is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ALW OCA].
	[[Category: Drosophila melanogaster]]		[[Category: Drosophila melanogaster]]
	[[Category: Mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase]]		[[Category: Mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase]]
-	[[Category: Single protein]]
	[[Category: Bols, M B.]]		[[Category: Bols, M B.]]
	[[Category: Kuntz, D A.]]		[[Category: Kuntz, D A.]]
Line 22:		Line 22:
	[[Category: Rose, D R.]]		[[Category: Rose, D R.]]
	[[Category: Glycosyl hydrolase family 38]]		[[Category: Glycosyl hydrolase family 38]]
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on ~~Sat May 3 19~~:12:~~06 2008~~''	+
		+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 18 06:21:35 2009''